ATE172975T1 - Benzimidezolderivate mit antidiabetischer und anti-plättchenklumpungswirkung - Google Patents

Benzimidezolderivate mit antidiabetischer und anti-plättchenklumpungswirkung

Info

Publication number
ATE172975T1
ATE172975T1 AT93401239T AT93401239T ATE172975T1 AT E172975 T1 ATE172975 T1 AT E172975T1 AT 93401239 T AT93401239 T AT 93401239T AT 93401239 T AT93401239 T AT 93401239T AT E172975 T1 ATE172975 T1 AT E172975T1
Authority
AT
Austria
Prior art keywords
derivatives
clugging
benzimidezole
platele
antidiabetic
Prior art date
Application number
AT93401239T
Other languages
English (en)
Inventor
Vera Alekseevna Anisimova
Margarita Valentinov Levchenko
Tatyana Borisovna Korochina
Alexander Alexeyevich Spasov
Sergei Gennadyevich Kovalev
Galina Petrovna Dudchenko
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9206036A external-priority patent/FR2691462B1/fr
Priority claimed from FR9209488A external-priority patent/FR2694293B1/fr
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE172975T1 publication Critical patent/ATE172975T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT93401239T 1992-05-19 1993-05-14 Benzimidezolderivate mit antidiabetischer und anti-plättchenklumpungswirkung ATE172975T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9206036A FR2691462B1 (fr) 1992-05-19 1992-05-19 Nouveaux derives du benzimidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR9209488A FR2694293B1 (fr) 1992-07-31 1992-07-31 Nouveau dérivé du benzimidazole, son procédé de préparation et les compositions pharmaceutiques qui le contiennent.

Publications (1)

Publication Number Publication Date
ATE172975T1 true ATE172975T1 (de) 1998-11-15

Family

ID=26229468

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93401239T ATE172975T1 (de) 1992-05-19 1993-05-14 Benzimidezolderivate mit antidiabetischer und anti-plättchenklumpungswirkung

Country Status (10)

Country Link
US (2) US5623073A (de)
EP (1) EP0571253B1 (de)
JP (1) JP2506263B2 (de)
AT (1) ATE172975T1 (de)
AU (1) AU656466B2 (de)
CA (1) CA2096475A1 (de)
DE (1) DE69321875T2 (de)
DK (1) DK0571253T3 (de)
ES (1) ES2126636T3 (de)
NZ (1) NZ247643A (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6147216A (en) * 1993-06-25 2000-11-14 Merrell Pharmaceuticals Inc. Intermediates useful for the preparation of antihistaminic piperidine derivatives
CA2362337C (en) 1993-06-25 2005-08-02 Merrell Pharmaceuticals Inc. Novel intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives
AUPN236595A0 (en) 1995-04-11 1995-05-11 Rescare Limited Monitoring of apneic arousals
FR2765223B1 (fr) * 1997-06-25 1999-08-27 Adir Nouveaux derives tricycliques du benzimidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6683094B2 (en) 1998-07-02 2004-01-27 Aventis Pharmaceuticals Inc. Antihistaminic piperidine derivatives and intermediates for the preparation thereof
US6730791B2 (en) 1998-07-02 2004-05-04 Aventis Pharmaceuticals Inc. Antihistaminic piperidine derivatives and intermediates for the preparation thereof
US6888004B2 (en) * 2001-01-26 2005-05-03 Bristol-Myers Squibb Company Imidazolyl derivatives as corticotropin releasing factor inhibitors
EP1753422B1 (de) * 2004-05-14 2008-05-28 The Cleveland Clinic Foundation Kleinmolekülige hemmer für mrp1 und andere multiarzneimitteltransporter
KR101449057B1 (ko) 2006-03-17 2014-10-10 암비트 바이오사이언시즈 코포레이션 질환 치료용 이미다졸로티아졸 화합물
BRPI0816904B8 (pt) 2007-09-19 2021-12-07 Ambit Biosciences Corp Forma cristalna b da forma sólida do sal de bis-hcl, composição farmacêutica, e, uso de uma forma sólida
RU2386634C2 (ru) * 2007-12-27 2010-04-20 Вера Алексеевна Анисимова Средство гемореологическое, снижающее инсулинорезистентность и восстанавливающее толерантность организма к глюкозе, и фармацевтическая композиция на его основе
WO2009120874A2 (en) * 2008-03-27 2009-10-01 Burnham Institute For Medical Research INHIBITORS OF ANTIGEN RECEPTOR-INDUCED NF-кB ACTIVATION
GB0808968D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substitute quinazolines
GB0808967D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substitute quinazolines
GB0808952D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
GB0808947D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
RU2391345C2 (ru) * 2008-07-23 2010-06-10 Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Южный Федеральный Университет" ДИГИДРОХЛОРИД 1-(3-МОРФОЛИНОПРОПИЛ)-2-ФЕНИЛИМИДАЗО[1,2-a]-БЕНЗИМИДАЗОЛА, ПРОЯВЛЯЮЩИЙ СВОЙСТВА АНТАГОНИСТА ПУРИНОВЫХ P2Y1-РЕЦЕПТОРОВ, АНТИАГРЕГАНТНУЮ И АНТИТРОМБОТИЧЕСКУЮ АКТИВНОСТЬ
CN103874702B (zh) * 2011-07-15 2015-12-09 杨森制药公司 作为γ分泌酶调节剂的经取代的吲哚衍生物
CA2995847C (en) * 2015-08-28 2024-05-28 Chdi Foundation, Inc. Probes for imaging huntingtin protein
CN108250202B (zh) * 2018-01-15 2019-10-25 陕西师范大学 2,3-二取代苯并咪唑并[1,2-a]嘧啶类化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732243A (en) * 1970-06-23 1973-05-08 Sankyo Co 2-(p-bromophenyl)-9-dimethyl-amino-propyl-9h-imidazo(1,2-a)benzimidazole
GB1476949A (en) * 1974-11-20 1977-06-16 Wyeth John & Brother Ltd Imidazo-1,2-a-benzimidazole and pyrimido-1,2-a-benzimidazole derivatives their preparation and their pharmaceutical compositions
US5008282A (en) * 1988-12-28 1991-04-16 Kotobuki Seiyaku Co. Ltd. Cyclic guanidine derivatives, anti-ulceratives and methods of manufacturing the same

Also Published As

Publication number Publication date
DK0571253T3 (da) 1999-07-19
EP0571253A1 (de) 1993-11-24
US5623073A (en) 1997-04-22
JP2506263B2 (ja) 1996-06-12
US5639756A (en) 1997-06-17
DE69321875T2 (de) 1999-06-17
EP0571253B1 (de) 1998-11-04
AU3860893A (en) 1993-11-25
NZ247643A (en) 1995-07-26
ES2126636T3 (es) 1999-04-01
CA2096475A1 (fr) 1993-11-20
DE69321875D1 (de) 1998-12-10
JPH0687859A (ja) 1994-03-29
AU656466B2 (en) 1995-02-02

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