ATE173635T1 - Akzeptabele pharmazeutische zusammensetzung enthaltend einen alkohol und einen hydrophalischen wirkstoff - Google Patents
Akzeptabele pharmazeutische zusammensetzung enthaltend einen alkohol und einen hydrophalischen wirkstoffInfo
- Publication number
- ATE173635T1 ATE173635T1 AT94914284T AT94914284T ATE173635T1 AT E173635 T1 ATE173635 T1 AT E173635T1 AT 94914284 T AT94914284 T AT 94914284T AT 94914284 T AT94914284 T AT 94914284T AT E173635 T1 ATE173635 T1 AT E173635T1
- Authority
- AT
- Austria
- Prior art keywords
- alcohol
- pct
- hydrophalic
- active
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ247516A NZ247516A (en) | 1993-04-28 | 1993-04-28 | Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE173635T1 true ATE173635T1 (de) | 1998-12-15 |
Family
ID=19924336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94914284T ATE173635T1 (de) | 1993-04-28 | 1994-04-22 | Akzeptabele pharmazeutische zusammensetzung enthaltend einen alkohol und einen hydrophalischen wirkstoff |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5843891A (de) |
| EP (1) | EP0696920B1 (de) |
| JP (1) | JPH08509475A (de) |
| CN (1) | CN1124457A (de) |
| AT (1) | ATE173635T1 (de) |
| AU (1) | AU677660B2 (de) |
| BR (1) | BR9406513A (de) |
| CA (1) | CA2160880A1 (de) |
| CZ (1) | CZ276995A3 (de) |
| DE (1) | DE69414840T2 (de) |
| FI (1) | FI955091A7 (de) |
| HU (1) | HUT73664A (de) |
| IL (1) | IL109401A0 (de) |
| MX (1) | MX9402922A (de) |
| NO (1) | NO954329L (de) |
| NZ (1) | NZ247516A (de) |
| PL (1) | PL311294A1 (de) |
| WO (1) | WO1994025068A1 (de) |
| ZA (1) | ZA942803B (de) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5858401A (en) | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
| CZ301382B6 (cs) * | 1997-03-12 | 2010-02-10 | Abbott Laboratories Chad377/Ap6D-2 | Hydrofilní binární systémy pro podávání cyklosporinu |
| US6258783B1 (en) | 1997-04-29 | 2001-07-10 | Bernard Charles Sherman | Emulsion preconcentrate comprising a cyclosporin and acetylated monoglyceride |
| NZ314702A (en) * | 1997-04-29 | 1998-07-28 | Bernard Charles Sherman | Pharmaceutical composition comprising a cyclosporin in a solvent system of acetylated monoglycerides and a surfactant and optionally a hydrophilic solvent |
| FR2764509A1 (fr) * | 1997-06-11 | 1998-12-18 | Debiopharm Sa | Compositions pharmaceutiques contenant du dichlorhydrate de cinchonine |
| KR100587551B1 (ko) | 1997-12-10 | 2006-06-08 | 싸이클로스포린 테라퓨틱스 리미티드 | 오메가-3 지방산 오일을 함유하는 약학 조성물 |
| US20030216303A1 (en) * | 1998-03-06 | 2003-11-20 | Michael Ambuhl | Emulsion preconcentrates containing cyclosporin or a macrolide |
| US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| US7258869B1 (en) * | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
| US20030157170A1 (en) * | 2001-03-13 | 2003-08-21 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
| US20030054036A1 (en) * | 2001-03-13 | 2003-03-20 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
| DK1392254T3 (da) | 2001-04-20 | 2007-07-02 | Univ British Columbia | Micelle-lægemiddelindgivelsessystem for hydrofobe lægemidler |
| US6592899B2 (en) | 2001-10-03 | 2003-07-15 | Macromed Incorporated | PLA/PLGA oligomers combined with block copolymers for enhancing solubility of a drug in water |
| PT1435910E (pt) * | 2001-10-19 | 2009-09-07 | Isotechnika Inc | Novos pré-concentrados de microemulsão de análogos da ciclosporina |
| WO2003053404A1 (en) * | 2001-12-20 | 2003-07-03 | Bernard Charles Sherman | Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
| WO2005053727A2 (en) * | 2003-11-29 | 2005-06-16 | Sangstat Medical Corporation | Pharmaceutical compositions for bioactive peptide agents |
| US7151085B2 (en) * | 2004-11-15 | 2006-12-19 | Allergan, Inc. | Therapeutic methods using cyclosporine components |
| US7135455B2 (en) * | 2004-11-15 | 2006-11-14 | Allergan, Inc | Methods for the therapeutic use of cyclosporine components |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US20080233053A1 (en) * | 2005-02-07 | 2008-09-25 | Pharmalight Inc. | Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients |
| WO2007140416A2 (en) | 2006-05-30 | 2007-12-06 | Intarcia Therapeutics, Inc. | Two-piece, internal-channel osmotic delivery system flow modulator |
| PT2359808E (pt) | 2006-08-09 | 2013-08-28 | Intarcia Therapeutics Inc | Sistemas de entrega osmótica e montagens de pistão |
| TWI394564B (zh) * | 2006-09-21 | 2013-05-01 | Alcon Res Ltd | 自行保存型水性藥學組成物 |
| ES2402172T3 (es) | 2007-04-23 | 2013-04-29 | Intarcia Therapeutics, Inc | Formulación en suspensión de péptidos insulinotrópicos y usos de los mismos |
| WO2009042114A2 (en) | 2007-09-21 | 2009-04-02 | The Johns Hopkins University | Phenazine derivatives and uses thereof |
| AU2008310956B2 (en) | 2007-10-08 | 2014-08-07 | Aurinia Pharmaceuticals Inc. | Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors |
| WO2009102467A2 (en) | 2008-02-13 | 2009-08-20 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
| US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
| US8906414B1 (en) | 2009-04-27 | 2014-12-09 | University Of South Florida | Methods and compositions for improving bioavailability of epigallocatechin gallate (EGCG) |
| MX338355B (es) | 2009-06-09 | 2016-04-13 | Aurinia Pharmaceuticals Inc | Sistemas de suministro de farmaco topico para uso oftalmico. |
| EP3735944A1 (de) | 2009-09-28 | 2020-11-11 | Intarcia Therapeutics, Inc. | Schnelle initiierung und/oder beendigung der verabreichung substantiell stabiler arzneimittel |
| US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| KR101211902B1 (ko) * | 2012-04-30 | 2012-12-13 | 주식회사 휴온스 | 사이클로스포린 함유 무자극성 나노에멀젼 안약 조성물 |
| ES2948387T3 (es) | 2012-08-24 | 2023-09-11 | Sun Pharmaceutical Ind Ltd | Formulación oftálmica de ácidos grasos polioxílicos o lípidos polioxílicos y tratamiento de afecciones oculares |
| US9498485B2 (en) | 2014-08-28 | 2016-11-22 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
| US20170246187A1 (en) | 2014-08-28 | 2017-08-31 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
| US10016363B2 (en) | 2014-09-18 | 2018-07-10 | Virun, Inc. | Pre-spray emulsions and powders containing non-polar compounds |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| KR102650751B1 (ko) | 2015-06-03 | 2024-03-22 | 인타르시아 세라퓨틱스 인코포레이티드 | 임플란트 배치 및 제거 시스템들 |
| US20160361322A1 (en) | 2015-06-15 | 2016-12-15 | Lipocine Inc. | Composition and method for oral delivery of androgen prodrugs |
| DK3373976T3 (da) | 2015-11-10 | 2024-04-02 | Sun Pharmaceutical Ind Ltd | Topiske formuleringer og anvendelser deraf |
| PT3423076T (pt) | 2016-02-29 | 2024-07-01 | Sun Pharmaceutical Ind Ltd | Formulações tópicas contendo ciclosporina e respetivas utilizações |
| CN109310743A (zh) | 2016-05-16 | 2019-02-05 | 因塔西亚制药公司 | 胰高血糖素受体选择性多肽及其使用方法 |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| US11559530B2 (en) | 2016-11-28 | 2023-01-24 | Lipocine Inc. | Oral testosterone undecanoate therapy |
| AU2018206539A1 (en) | 2017-01-03 | 2019-07-18 | Intarcia Therapeutics, Inc. | Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug |
| US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| EP3824296A4 (de) | 2018-07-20 | 2022-04-27 | Lipocine Inc. | Lebererkrankung |
| JP2026027576A (ja) * | 2022-11-22 | 2026-02-19 | 一丸ファルコス株式会社 | Ras阻害ペプチドを含む組成物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS498246B1 (de) * | 1965-07-15 | 1974-02-25 | ||
| JPS5919525B2 (ja) * | 1976-09-03 | 1984-05-07 | 武田薬品工業株式会社 | 注射剤 |
| FI65914C (fi) * | 1978-03-07 | 1984-08-10 | Sandoz Ag | Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a |
| GB8903804D0 (en) * | 1989-02-20 | 1989-04-05 | Sandoz Ltd | Improvements in or relating to organic compounds |
| JPS6226220A (ja) * | 1985-07-29 | 1987-02-04 | Hishiyama Seiyaku Kk | ケトプロフエン注射液 |
| JP2577049B2 (ja) * | 1987-06-04 | 1997-01-29 | 三共株式会社 | シクロスポリン製剤 |
| CH679119A5 (de) * | 1988-05-13 | 1991-12-31 | Sandoz Ag | |
| KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
| HU208491B (en) * | 1990-11-27 | 1993-11-29 | Gyogyszerkutato Intezet | Process for producing oral pharmaceutical composition containing cyclosporin |
| GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
| JPH0558906A (ja) * | 1991-09-06 | 1993-03-09 | Sankyo Co Ltd | シクロスポリン点眼製剤 |
-
1993
- 1993-04-28 NZ NZ247516A patent/NZ247516A/en unknown
-
1994
- 1994-04-22 CN CN94192265A patent/CN1124457A/zh active Pending
- 1994-04-22 CA CA002160880A patent/CA2160880A1/en not_active Abandoned
- 1994-04-22 ZA ZA942803A patent/ZA942803B/xx unknown
- 1994-04-22 EP EP94914284A patent/EP0696920B1/de not_active Expired - Lifetime
- 1994-04-22 PL PL94311294A patent/PL311294A1/xx unknown
- 1994-04-22 CZ CZ952769A patent/CZ276995A3/cs unknown
- 1994-04-22 WO PCT/CA1994/000222 patent/WO1994025068A1/en not_active Ceased
- 1994-04-22 MX MX9402922A patent/MX9402922A/es not_active Application Discontinuation
- 1994-04-22 HU HU9503075A patent/HUT73664A/hu unknown
- 1994-04-22 BR BR9406513A patent/BR9406513A/pt not_active Application Discontinuation
- 1994-04-22 JP JP6523695A patent/JPH08509475A/ja active Pending
- 1994-04-22 AU AU66734/94A patent/AU677660B2/en not_active Ceased
- 1994-04-22 IL IL10940194A patent/IL109401A0/xx unknown
- 1994-04-22 DE DE69414840T patent/DE69414840T2/de not_active Expired - Fee Related
- 1994-04-22 AT AT94914284T patent/ATE173635T1/de not_active IP Right Cessation
- 1994-04-22 FI FI955091A patent/FI955091A7/fi not_active Application Discontinuation
- 1994-04-22 US US08/537,697 patent/US5843891A/en not_active Expired - Fee Related
-
1995
- 1995-10-27 NO NO954329A patent/NO954329L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI955091L (fi) | 1995-12-14 |
| EP0696920B1 (de) | 1998-11-25 |
| MX9402922A (es) | 1997-05-31 |
| HUT73664A (en) | 1996-09-30 |
| HU9503075D0 (en) | 1995-12-28 |
| NO954329L (no) | 1995-12-21 |
| US5843891A (en) | 1998-12-01 |
| CA2160880A1 (en) | 1994-11-10 |
| IL109401A0 (en) | 1994-11-28 |
| WO1994025068A1 (en) | 1994-11-10 |
| AU677660B2 (en) | 1997-05-01 |
| EP0696920A1 (de) | 1996-02-21 |
| AU6673494A (en) | 1994-11-21 |
| PL311294A1 (en) | 1996-02-05 |
| CN1124457A (zh) | 1996-06-12 |
| ZA942803B (en) | 1996-01-22 |
| CZ276995A3 (en) | 1996-03-13 |
| FI955091A7 (fi) | 1995-12-14 |
| FI955091A0 (fi) | 1995-10-25 |
| NO954329D0 (no) | 1995-10-27 |
| BR9406513A (pt) | 1996-01-09 |
| DE69414840D1 (de) | 1999-01-07 |
| NZ247516A (en) | 1995-02-24 |
| JPH08509475A (ja) | 1996-10-08 |
| DE69414840T2 (de) | 1999-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |