ATE173732T1 - 8-(1-aminocycloalkyl)-1,3-dialkylxanthinderivat als antagonisten von adenosinrezeptoren - Google Patents

8-(1-aminocycloalkyl)-1,3-dialkylxanthinderivat als antagonisten von adenosinrezeptoren

Info

Publication number
ATE173732T1
ATE173732T1 AT93100723T AT93100723T ATE173732T1 AT E173732 T1 ATE173732 T1 AT E173732T1 AT 93100723 T AT93100723 T AT 93100723T AT 93100723 T AT93100723 T AT 93100723T AT E173732 T1 ATE173732 T1 AT E173732T1
Authority
AT
Austria
Prior art keywords
aminocycloalkyl
dialkylxanthine
antagonists
derivative
adenosine receptors
Prior art date
Application number
AT93100723T
Other languages
English (en)
Inventor
Mario Brufani
Stefano Ceccarelli
Vellis Patrizia De
Patrizia Giannetti
Agnese Paesano
Romolo Scuri
Sergio Zanarella
Original Assignee
Foscama Biomed Chim Farma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foscama Biomed Chim Farma filed Critical Foscama Biomed Chim Farma
Application granted granted Critical
Publication of ATE173732T1 publication Critical patent/ATE173732T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT93100723T 1992-01-24 1993-01-19 8-(1-aminocycloalkyl)-1,3-dialkylxanthinderivat als antagonisten von adenosinrezeptoren ATE173732T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920132A IT1260444B (it) 1992-01-24 1992-01-24 Derivati della 8-(1-amminocicloalchil)1,3-dialchilxantina, procedimenbto di preparazione e loro composizioni farmaceutiche antidepressive, nootropiche e psicostimolanti

Publications (1)

Publication Number Publication Date
ATE173732T1 true ATE173732T1 (de) 1998-12-15

Family

ID=11361662

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93100723T ATE173732T1 (de) 1992-01-24 1993-01-19 8-(1-aminocycloalkyl)-1,3-dialkylxanthinderivat als antagonisten von adenosinrezeptoren

Country Status (10)

Country Link
US (1) US5378844B1 (de)
EP (1) EP0552712B1 (de)
CN (1) CN1035877C (de)
AT (1) ATE173732T1 (de)
CA (1) CA2087922C (de)
DE (1) DE69322177T2 (de)
DK (1) DK0552712T3 (de)
ES (1) ES2125911T3 (de)
GR (1) GR3029476T3 (de)
IT (1) IT1260444B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2176204T3 (es) * 1992-07-08 2002-12-01 Kyowa Hakko Kogyo Kk Antidepresivos que contienen un derivado de xantina.
DE4316576A1 (de) * 1993-05-18 1994-11-24 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 1,3-Dipropyl-8-(3-Oxocyclopentyl)-xanthin
CA2148502A1 (en) * 1993-09-06 1995-03-16 Fumio Suzuki Antidepressants
US6117870A (en) * 1998-11-12 2000-09-12 Fujirebio Kabushiki Kaisha Cyclic amide derivatives
CN1436175A (zh) 2000-04-03 2003-08-13 布里斯托尔-迈尔斯斯奎布药品公司 作为Aβ－蛋白生产抑制剂的环状内酰胺
FR2814077A1 (fr) * 2000-09-20 2002-03-22 Inst Nat Sante Rech Med Utilisation de modulateurs de recepteurs a l'adenosine pour reguler la fonction des netrines et/ou de leurs recepteurs
KR100710453B1 (ko) * 2003-05-13 2007-04-24 에프. 호프만-라 로슈 아게 아데노신 수용체 리간드로서의 2-이미다조-벤조싸이아졸

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2879271A (en) * 1953-07-23 1959-03-24 Knoll Ag Basic derivatives of mono- and dimethyl xanthines, and a process of making same
EP0011399A1 (de) * 1978-11-11 1980-05-28 FISONS plc N-Substituierte Theophylline, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
US4772607A (en) * 1986-05-20 1988-09-20 Warner-Lambert Company Dialkenyl derivatives of xanthine, pharmaceutical compositions and methods of use therefor
DE8817122U1 (de) * 1988-12-22 1993-02-04 Boehringer Ingelheim Kg, 55218 Ingelheim Neue Xanthinderivate mit Adenosinantogenistischer Wirkung
JP2843634B2 (ja) * 1989-03-06 1999-01-06 協和醗酵工業株式会社 キサンチン誘導体
DE4019892A1 (de) * 1990-06-22 1992-01-02 Boehringer Ingelheim Kg Neue xanthinderivate

Also Published As

Publication number Publication date
CN1082047A (zh) 1994-02-16
CN1035877C (zh) 1997-09-17
DK0552712T3 (da) 1999-08-09
DE69322177D1 (de) 1999-01-07
US5378844B1 (en) 1998-12-01
EP0552712A1 (de) 1993-07-28
CA2087922C (en) 2004-11-30
EP0552712B1 (de) 1998-11-25
CA2087922A1 (en) 1993-07-25
IT1260444B (it) 1996-04-09
GR3029476T3 (en) 1999-05-28
DE69322177T2 (de) 1999-06-24
ES2125911T3 (es) 1999-03-16
US5378844A (en) 1995-01-03
ITMI920132A1 (it) 1993-07-24
ITMI920132A0 (it) 1992-01-24

Similar Documents

Publication Publication Date Title
CL2003002756A1 (es) Compuestos derivados de (1-carbamoil-1,1-defenilmetil)-1-[substituido)alquil]purrolidinas; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento del sindrome de intestino irritable o incontinencia.
BG101715A (bg) Тетрациклени спиросъединения,метод за тяхното получаване и приложението им като 5нт долу 1d рецепторни антагонисти
ES2002599A6 (es) Un procedimiento para la preparacion de la sal de besilato de amlodipina
FI944729L (fi) Perhydroisoindolijohdannaiset substanssi P:n antagonisteina
IL119729A0 (en) Heterocyclic compounds having tachykinin receptor antagonist activity pharmaceutical compositions containing the same and processes for the preparation thereof
MX9201356A (es) Derivados de piperidina, procedimiento para su preparacion y composicion farmaceutica que los contiene.
FI944394A7 (fi) Kinuklidiinijohdannaisia P-aineen antagonisteina
EE03177B1 (et) Heterobitsüklilised ühendid, nende saamismeetod ja nimetatud ühendeid sisaldavad farmatseutilised kompositsioonid
SE8602723L (sv) Tiazoler, deras framstellning och farmaceutiska kompositioner innehallande dem
FR2677984B1 (fr) Derives d'imidazoline n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
FR2681067B1 (fr) Derives heterocycliques n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
NO951283D0 (no) Nye taxanderivater, deres fremstilling samt farmasöytiske preparater inneholdende derivatene
ATE173732T1 (de) 8-(1-aminocycloalkyl)-1,3-dialkylxanthinderivat als antagonisten von adenosinrezeptoren
DE3585990D1 (de) Derivate von hydroxy- oder amino-substituierten piperidinylalkylchinazolinen.
ATE33655T1 (de) Triazin-derivat, verfahren zu seiner herstellung und dieses enthaltende pharmazeutische zubereitungen.
PT91203A (pt) Processo para a preparacao de novos derivados de antibioticos bu-3608 e de composicoes farmaceuticas que os contem
SE8302979L (sv) Piperazinderivat, deras framstellning och farmaceutiska kompositioner innehallande dessa
FI951798A0 (fi) Bentsofuraanijohdannaiset 5-HT1-kaltaisina reseptoriantagonisteina
DE69514315D1 (de) AZABICYCLOALKYLDERIVATE VON IMIDAZO[1,5-a]INDOL-3-ONE ALS 5HT3 ANTAGONISTEN
ATE79540T1 (de) Pharmazeutische zusammensetzung.
ATE237619T1 (de) Sesquiterpen-derivate mit antiviraler aktivität
FI895937A7 (fi) Uusia imidatsolidiinijohdannaisia, menetelmiä niiden valmistamiseksi, kuten myös näitä yhdisteitä sisältäviä lääkkeitä
DE69000806D1 (de) Indol-derivate.
DE3783821D1 (de) Tetracyclische indolderivate.
IL95409A0 (en) Substituted n-heterocyclic five-membered ring derivatives,their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee