ATE173935T1 - Verfahren zur isolierung und reinigung von rezeptoren für transferrin und lactoferrin von bakterien und herstellung von impfstoffen, die sie enthalten - Google Patents

Verfahren zur isolierung und reinigung von rezeptoren für transferrin und lactoferrin von bakterien und herstellung von impfstoffen, die sie enthalten

Info

Publication number: ATE173935T1
Authority: AT; Austria
Prior art keywords: lactoferrin; transferrin; receptors; bacteria; isolation
Prior art date: 1989-04-27

Application number

AT90906093T

Other languages

English (en)

Inventor

Anthony Bernard Schryvers

Original Assignee

Univ Technologies Int

Anthony Bernard Schryvers

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-27

Filing date

1990-04-26

Publication date

1998-12-15

1990-04-26 Application filed by Univ Technologies Int, Anthony Bernard Schryvers filed Critical Univ Technologies Int

1998-12-15 Application granted granted Critical

1998-12-15 Publication of ATE173935T1 publication Critical patent/ATE173935T1/de

Links

102000004338 Transferrin Human genes 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
239000012581 transferrin Substances 0.000 title abstract 2
229960005486 vaccine Drugs 0.000 title abstract 2
241000894006 Bacteria Species 0.000 title 1
102000010445 Lactoferrin Human genes 0.000 title 1
108010063045 Lactoferrin Proteins 0.000 title 1
108090000901 Transferrin Proteins 0.000 title 1
238000002955 isolation Methods 0.000 title 1
CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 title 1
229940078795 lactoferrin Drugs 0.000 title 1
235000021242 lactoferrin Nutrition 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
XNSAINXGIQZQOO-SRVKXCTJSA-N protirelin Chemical compound NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H]1NC(=O)CC1)CC1=CN=CN1 XNSAINXGIQZQOO-SRVKXCTJSA-N 0.000 title 1
238000000746 purification Methods 0.000 title 1
108010033576 Transferrin Receptors Proteins 0.000 abstract 1
238000001042 affinity chromatography Methods 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
244000052616 bacterial pathogen Species 0.000 abstract 1
108010071397 lactoferrin receptors Proteins 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
108020003175 receptors Proteins 0.000 abstract 1
102000005962 receptors Human genes 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Microbiology (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Biophysics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT90906093T 1989-04-27 1990-04-26 Verfahren zur isolierung und reinigung von rezeptoren für transferrin und lactoferrin von bakterien und herstellung von impfstoffen, die sie enthalten ATE173935T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US34435689A	1989-04-27	1989-04-27
US07/507,481 US5292869A (en)	1989-04-27	1990-04-09	Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same

Publications (1)

Publication Number	Publication Date
ATE173935T1 true ATE173935T1 (de)	1998-12-15

Family

ID=26993881

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90906093T ATE173935T1 (de)	1989-04-27	1990-04-26	Verfahren zur isolierung und reinigung von rezeptoren für transferrin und lactoferrin von bakterien und herstellung von impfstoffen, die sie enthalten

Country Status (12)

Country	Link
US (1)	US5292869A (de)
EP (1)	EP0528787B1 (de)
KR (1)	KR100240974B1 (de)
AT (1)	ATE173935T1 (de)
AU (1)	AU649950B2 (de)
CA (1)	CA2051808C (de)
DE (1)	DE69032806T2 (de)
DK (1)	DK0528787T3 (de)
ES (1)	ES2127184T3 (de)
IL (2)	IL94228A (de)
NZ (2)	NZ233471A (de)
WO (1)	WO1990012591A1 (de)

Families Citing this family (38)

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ES2329979T3 (es) *	1990-08-23	2009-12-03	The University Of North Carolina At Chapel Hill	Proteinas de union de transferencia de neisseria gonorrhoeae y neisseria meningitis. su uso como vacuna.
FR2682114B1 (fr) *	1991-10-03	1996-02-23	Pasteur Merieux Serums Vacc	Vaccin de sous-unite contre les infections a neisseria meningitidis et sous-unites correspondantes a l'etat purifie.
FR2682041B1 (fr) *	1991-10-03	1994-01-14	Pasteur Merieux Serums Vaccins	Vaccin contre les infections a neisseria meningitidis.
US5417971A (en) *	1991-10-22	1995-05-23	University Of Saskatchewan	Vaccines for Actinobacillus pleuropneumoniae
FR2692592B1 (fr) *	1992-06-19	1995-03-31	Pasteur Merieux Serums Vacc	Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant.
US5534256A (en) *	1992-07-02	1996-07-09	University Of Saskatchewan	Haemophilus somnus outer membrane protein extract enriched with iron-regulated proteins
WO1994005783A1 (en) *	1992-09-07	1994-03-17	Bioproperties (Australia) Pty. Limited	Novel haemophilus organism and vaccines containing the same
DK0749321T3 (da)	1994-02-09	2007-03-12	Epitopix Llc	Aktiv immunisering under anvendelse af et sideroforreceptorprotein
US5830479A (en) *	1994-02-09	1998-11-03	Willmar Poultry Company, Inc.	Active immunization using a siderophore receptor protein
US6121427A (en) *	1994-10-24	2000-09-19	Connaught Laboratories Limited	Major outer membrane protein CD of branhamella
US6440425B1 (en) *	1995-05-01	2002-08-27	Aventis Pasteur Limited	High molecular weight major outer membrane protein of moraxella
US5817789A (en)	1995-06-06	1998-10-06	Transkaryotic Therapies, Inc.	Chimeric proteins for use in transport of a selected substance into cells
US6290970B1 (en)	1995-10-11	2001-09-18	Aventis Pasteur Limited	Transferrin receptor protein of Moraxella
US6048539A (en) *	1995-11-02	2000-04-11	Connaught Laboratories Limited	Lactoferrin receptor protein
US6610506B1 (en)	1995-12-01	2003-08-26	University Technologies International, Inc.	Transferrin binding proteins of Pasteurella haemolytica and vaccines containing same
JP2000502249A (ja) *	1995-12-01	2000-02-29	ロウ、レジー・ワイ・シー	パスツレラ・ヘモリチカのトランスフェリン結合タンパク質およびそれを含有するワクチン
US6090576A (en) *	1996-03-08	2000-07-18	Connaught Laboratories Limited	DNA encoding a transferrin receptor of Moraxella
US6440701B1 (en)	1996-03-08	2002-08-27	Aventis Pasteur Limited	Transferrin receptor genes of Moraxella
ES2271987T3 (es) *	1997-01-31	2007-04-16	Wyeth Holdings Corporation	Proteina de 74 kilodalton de la membrana externa de moraxella catarrhalis.
US5977337A (en)	1997-06-03	1999-11-02	Connaught Laboratories Limited	Lactoferrin receptor genes of Moraxella
AU739129B2 (en) *	1997-06-03	2001-10-04	Connaught Laboratories Limited	Lactoferrin receptor genes of moraxella
FR2767060B1 (fr) *	1997-08-07	2000-02-11	Pasteur Merieux Serums Vacc	Vaccin meningocoque comportant la valence de souche bz83
GB9810084D0 (en)	1998-05-11	1998-07-08	Cortecs Uk Ltd	Proteins
FR2785293B1 (fr)	1998-10-30	2002-07-05	Pasteur Merieux Serums Vacc	Acides nucleiques et polypeptides specifiques des souches pathogenes du genre neisseria
GB9823978D0 (en) *	1998-11-02	1998-12-30	Microbiological Res Authority	Multicomponent meningococcal vaccine
US10967045B2 (en)	1998-11-02	2021-04-06	Secretary of State for Health and Social Care	Multicomponent meningococcal vaccine
US6391316B1 (en) *	1999-03-10	2002-05-21	University Of Saskatchewan	Vaccine compositions comprising Haemophilus somnus transferrin-binding proteins and methods of use
US7241449B1 (en)	1999-04-12	2007-07-10	Aventis Pasteur Limited	Transferrin receptor genes of moraxella
US6682754B2 (en)	1999-11-24	2004-01-27	Willmar Poultry Company, Inc.	Ovo delivery of an immunogen containing implant
MXPA03006038A (es) *	2001-01-03	2005-02-14	Willmar Poultry Co Inc	Composiciones inmunizantes y metodos de uso.
US8129504B2 (en) *	2001-08-30	2012-03-06	Biorexis Technology, Inc.	Oral delivery of modified transferrin fusion proteins
US7759055B2 (en) *	2002-08-28	2010-07-20	Millipore Corporation	Compositions of solution for sequencing reaction clean-up
AU2004274977B2 (en)	2003-09-19	2011-06-23	Epitopix, Llc	Campylobacter polypeptides and methods of use
US8007811B2 (en)	2005-02-14	2011-08-30	Epitopix, Llc	Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use
BRPI1011856A2 (pt)	2009-03-23	2020-11-03	Epitopix, Llc	polipeptídeos e composições de imunização contendo polipeptídeos gram-positivos e métodos de uso
CA2818173C (en)	2010-11-30	2022-05-03	Genentech, Inc.	Low affinity blood brain barrier receptor antibodies and uses therefor
ES2912751T3 (es)	2013-12-02	2022-05-27	Eng Antigens Inc	Composiciones inmunogénicas y vacunas derivadas de proteínas receptoras de superficie bacteriana
US10166280B2 (en)	2016-06-08	2019-01-01	Epitopix, Llc	Polypeptides and immunizing compositions containing Bacillus polypeptides and methods of use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2227861B1 (de) *	1973-05-04	1976-07-02	Anvar
US4220638A (en) *	1978-10-12	1980-09-02	Merck & Co., Inc.	Antigenic complex from N. Gonorrhoeae
US4271147A (en) *	1980-01-10	1981-06-02	Behringwerke Aktiengesellschaft	Process for the isolation of membrane proteins from Neisseria meningitidis and vaccines containing same
US4447547A (en) *	1980-04-09	1984-05-08	University Patents, Inc.	Immunoassay for measurement of reticulocytes, and immunoreactive reagents for use therein
US4434156A (en) *	1981-10-26	1984-02-28	The Salk Institute For Biological Studies	Monoclonal antibodies specific for the human transferrin receptor glycoprotein
US4681761A (en) *	1985-10-24	1987-07-21	State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University	Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine
AU626288B2 (en) *	1988-02-05	1992-07-30	Commonwealth Scientific And Industrial Research Organisation	Gene expression system (particularly for rotavirus vp7 protein) involving a foreign signal peptide and optionally a transmembrane anchor sequence
FR2644346B1 (fr) *	1989-03-20	1994-05-13	Rhone Merieux	Vaccins contre les bacteries septicemiques, preparations d'antigenes de bacteries septicemiques, nouvelles bacteries et vecteurs pour la preparation de ces antigenes ou vaccins

1990
- 1990-04-09 US US07/507,481 patent/US5292869A/en not_active Expired - Fee Related
- 1990-04-26 WO PCT/CA1990/000131 patent/WO1990012591A1/en not_active Ceased
- 1990-04-26 EP EP90906093A patent/EP0528787B1/de not_active Expired - Lifetime
- 1990-04-26 AT AT90906093T patent/ATE173935T1/de not_active IP Right Cessation
- 1990-04-26 CA CA002051808A patent/CA2051808C/en not_active Expired - Fee Related
- 1990-04-26 DK DK90906093T patent/DK0528787T3/da active
- 1990-04-26 AU AU55261/90A patent/AU649950B2/en not_active Ceased
- 1990-04-26 ES ES90906093T patent/ES2127184T3/es not_active Expired - Lifetime
- 1990-04-26 KR KR1019910701442A patent/KR100240974B1/ko not_active Expired - Fee Related
- 1990-04-26 DE DE69032806T patent/DE69032806T2/de not_active Expired - Fee Related
- 1990-04-27 NZ NZ233471A patent/NZ233471A/en unknown
- 1990-04-27 IL IL9422890A patent/IL94228A/en not_active IP Right Cessation
- 1990-04-27 NZ NZ247967A patent/NZ247967A/en unknown
2001
- 2001-08-19 IL IL14497301A patent/IL144973A0/xx unknown

Also Published As

Publication number	Publication date
KR100240974B1 (ko)	2000-08-01
IL94228A (en)	2001-03-19
AU5526190A (en)	1990-11-16
DE69032806D1 (de)	1999-01-14
US5292869A (en)	1994-03-08
CA2051808C (en)	1999-12-14
DK0528787T3 (da)	1999-08-16
ES2127184T3 (es)	1999-04-16
EP0528787A1 (de)	1993-03-03
CA2051808A1 (en)	1990-10-28
NZ247967A (en)	1995-02-24
NZ233471A (en)	1993-11-25
KR920700688A (ko)	1992-08-10
IL144973A0 (en)	2002-06-30
WO1990012591A1 (en)	1990-11-01
IL94228A0 (en)	1991-01-31
AU649950B2 (en)	1994-06-09
EP0528787B1 (de)	1998-12-02
DE69032806T2 (de)	1999-08-05

Legal Events

Date	Code	Title	Description
1999-09-15	UEP	Publication of translation of european patent specification
2005-01-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE173935T1 (de)	1998-12-15	Verfahren zur isolierung und reinigung von rezeptoren für transferrin und lactoferrin von bakterien und herstellung von impfstoffen, die sie enthalten
DE3783191D1 (de)	1993-02-04	Verfahren und mittel zur herstellung eines proteins mit der gleichen igg-spezifizitaet wie protein g.
PL374311A1 (en)	2005-10-03	Methods for purifying protein
DE69032922D1 (de)	1999-03-11	Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff
ATE278785T1 (de)	2004-10-15	Neues verfahren zur gewinnung und reinigung von fusionsproteinen
DE122005000035I1 (de)	2005-10-20	Verfahren zur Reinigung von waessrigen Extrakten, die allergenische Proteine enthalten, so erhalteneExtrakte und ihre Verwendung.
ATE40651T1 (de)	1989-02-15	Verfahren zur reinigung bioaktiver substanzen durch biospezifische adsorption.
PT91750A (pt)	1990-03-30	Processo para a preparacao de factor de crescimento de celulas t auxiliares
DE3686954D1 (de)	1992-11-19	Loeslichkeits-, reinigungs- und charakterisierungsverfahren fuer proteine aus unloeslichen proteinaggregaten oder proteinkomplexen und diesbezuegliche praeparate.
DK0680765T3 (da)	2007-07-02	Vaccine til ikke-typebestemmelig Haemophilus influenzae-stamme
ATE57936T1 (de)	1990-11-15	Material fuer affinitaetschromatographie und dessen anwendung zur trennung und reinigung von proteinischen antigenen von bakterien des genus bordetella.
ATE72829T1 (de)	1992-03-15	In einem serumfreien medium in suspension kultivierte humane monozyten.
DE3686961D1 (de)	1992-11-19	Polydisperse native pseudomonas-flagella(h)-antigene (fag) und verfahren zu ihrer gewinnung.
DK0474645T3 (da)	2000-03-27	Proteinkompleks
ATE91304T1 (de)	1993-07-15	Verfahren zur herstellung des pres 1/s2/shepatitis-b-antigens aus hefe.
ATE155481T1 (de)	1997-08-15	Verfahren zur reinigung von streptolysin 0, intaktes streptolysin 0 erhältlich nach diesem verfahren und seine verwendung
ATE79853T1 (de)	1992-09-15	Verfahren zur teilweisen reinigung eines oxyiodierungsproduktes.
RU2067767C1 (ru)	1996-10-10	Способ получения субъединичной генноинженерной вакцины против гепатита в
DE69026912D1 (de)	1996-06-13	Verfahren zur Herstellung von Nojirimycin-Verbindungen
AU603794C (en)	1994-01-06	Affinity chromatography method for the separation and purification of protein antigens of the bacteria of the bordetella genus
RO94839B1 (ro)	1988-07-31	Procedeu de preparare a peptonei
ATA264687A (de)	1990-12-15	Beta-lactamverbindungen, verfahren zu ihrer herstellung, dieselben enthaltende pharmazeutischepraeparate zur behandlung von durch bakterien verursachte infektionskrankheiten