ATE174382T1 - Retrovirus aus der hiv-gruppe und dessen verwendung - Google Patents

Retrovirus aus der hiv-gruppe und dessen verwendung

Info

Publication number
ATE174382T1
ATE174382T1 AT93116058T AT93116058T ATE174382T1 AT E174382 T1 ATE174382 T1 AT E174382T1 AT 93116058 T AT93116058 T AT 93116058T AT 93116058 T AT93116058 T AT 93116058T AT E174382 T1 ATE174382 T1 AT E174382T1
Authority
AT
Austria
Prior art keywords
mvp
cdna
retrovirus
hiv
recombinant dna
Prior art date
Application number
AT93116058T
Other languages
German (de)
English (en)
Inventor
Lutz G Prof Dr Guertler
Josef Dr Eberle
V Albrecht Dr Brunn
Stefan Dr Knapp
Hans-Peter Dr Hauser
Original Assignee
Dade Behring Marburg Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27435590&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE174382(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE4233646A external-priority patent/DE4233646C2/de
Priority claimed from DE4235718A external-priority patent/DE4235718A1/de
Priority claimed from DE4244541A external-priority patent/DE4244541A1/de
Priority claimed from DE4318186A external-priority patent/DE4318186C2/de
Application filed by Dade Behring Marburg Gmbh filed Critical Dade Behring Marburg Gmbh
Application granted granted Critical
Publication of ATE174382T1 publication Critical patent/ATE174382T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • G01N33/56988HIV or HTLV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
AT93116058T 1992-10-06 1993-10-05 Retrovirus aus der hiv-gruppe und dessen verwendung ATE174382T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4233646A DE4233646C2 (de) 1992-10-06 1992-10-06 Retrovirus aus der HIV-Gruppe und dessen Verwendung
DE4235718A DE4235718A1 (de) 1992-10-22 1992-10-22 Retrovirus aus der HIV-Gruppe und dessen Verwendung
DE4244541A DE4244541A1 (de) 1992-12-30 1992-12-30 Retrovirus aus der HIV-Gruppe und dessen Verwendung
DE4318186A DE4318186C2 (de) 1993-06-01 1993-06-01 Retrovirus aus der HIV-Gruppe und dessen Verwendung

Publications (1)

Publication Number Publication Date
ATE174382T1 true ATE174382T1 (de) 1998-12-15

Family

ID=27435590

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93116058T ATE174382T1 (de) 1992-10-06 1993-10-05 Retrovirus aus der hiv-gruppe und dessen verwendung

Country Status (9)

Country Link
US (12) US5840480A (da)
EP (2) EP0890642A3 (da)
JP (4) JP3277045B2 (da)
AT (1) ATE174382T1 (da)
AU (1) AU677225B2 (da)
CA (1) CA2107732C (da)
DE (1) DE59309207D1 (da)
DK (1) DK0591914T4 (da)
ES (1) ES2126620T5 (da)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856088A (en) * 1989-07-11 1999-01-05 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
US6589734B1 (en) 1989-07-11 2003-07-08 Gen-Probe Incorporated Detection of HIV
KR100257941B1 (ko) 1992-03-06 2000-06-01 휴버스윗 에이치. 밴 면역학적으로 중요한 에피토프에 상응하는 펩티드의 측정 방법 및 면역학적으로 중요한 에피토프에 상응하는 항체 또는 비오티닐화된 펩티드의 측정 방법에 상기 펩티드를 사용하는 방법, 상기 펩티드의 제조 방법 및 상기 펩티드를 함유하는 조성물
JP3277045B2 (ja) * 1992-10-06 2002-04-22 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング Hiv−グループのレトロウイルスおよびその使用
KR100325554B1 (ko) 1993-03-26 2002-11-02 젠-프로브 인코포레이티드 사람의면역결핍 바이러스타입1의검출
DE4405810A1 (de) 1994-02-23 1995-08-24 Behringwerke Ag Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung
GB9410044D0 (en) * 1994-05-19 1994-07-06 Int Murex Tech Corp Assay
FR2726006B1 (fr) * 1994-10-20 1996-12-27 Pasteur Institut Sequences nucleotidiques codant des antigenes d'un retrovirus du type vih-1 groupe o
ES2293643T5 (es) 1994-10-20 2012-02-02 Institut Pasteur Secuencias nucleotídicas de antígenos retrovíricos vih-1 del grupo (o subgrupo) o.
FR2731225B1 (fr) * 1995-03-03 2003-10-31 Pasteur Institut Peptides de glycoproteine transmembranaire d'enveloppe et de proteine de capside du retrovirus humain du type hiv-1 et peptides presentant avec eux une parente immunologique
DE19505262C2 (de) * 1995-02-16 1998-06-18 Behring Diagnostics Gmbh Retrovirus aus der HIV-Gruppe und dessen Verwendung
US6548635B1 (en) * 1995-02-16 2003-04-15 Dade Behring Marburg Gmbh Retrovirus from the HIV type O and its use (MVP-2901/94)
US5599662A (en) * 1995-02-17 1997-02-04 Hoffmann-La Roche Inc. Oliconucleotide primers and probes for the detection of HIV-1
WO1996027012A1 (en) * 1995-03-02 1996-09-06 Akzo Nobel N.V. Specific hiv-1 group o antigens
CA2222994A1 (en) * 1995-06-07 1996-12-19 Abbott Laboratories Peptides for hiv-1 detection
US5733732A (en) * 1996-01-03 1998-03-31 University Of Iowa Research Foundation Methods for detecting primary adhalinopathy
JPH11502727A (ja) 1996-01-26 1999-03-09 イノジェネティックス・ナムローゼ・フェンノートシャップ 逆転写酵素遺伝子における薬剤により誘発された変異の検出方法
DE19644248A1 (de) * 1996-10-24 1998-04-30 Boehringer Mannheim Gmbh Primer und Probes zum Nachweis von HIV
AU6589698A (en) 1997-03-28 1998-10-22 Epitope, Inc. Simultaneous collection of dna and non-nucleic analytes from oral fluids
CN1215082C (zh) 1997-04-09 2005-08-17 比奥-拉德巴斯德公司 可用于检测o组hiv-1病毒感染的生物试验的合成肽
US6846905B2 (en) 1997-08-15 2005-01-25 Abbott Laboratories Antigen constructs useful in the detection and differentiation of antibodies to HIV
US5922533A (en) * 1997-08-15 1999-07-13 Abbott Laboratories Rapid assay for simultaneous detection and differentiation of antibodies to HIV groups
DE19737442C2 (de) * 1997-08-22 1999-06-24 Olfert Landt Tib Molbiol Synth Proteinumhüllte Polyribonukleinsäuren, ein Verfahren zu ihrer Herstellung und ihre Verwendung
US6228128B1 (en) 1997-11-10 2001-05-08 Charlotte Johansen Antimicrobial activity of laccases
AU2345399A (en) * 1998-01-28 1999-08-16 Universal Health-Watch, Inc. Divergent hiv-1 peptides
CA2288869A1 (en) * 1998-03-04 1999-09-10 Mary Ann Childs Rapid confirmatory test for microbial infections
WO1999062945A2 (en) * 1998-06-05 1999-12-09 Peptide Solutions, Inc. Peptide antigens for detection of hiv, hcv and other microbial infections
CA2290217C (en) * 1998-11-30 2010-01-12 Ortho-Clinical Diagnostics, Inc. Peptides for the detection of hiv-1 group o
US6303293B1 (en) * 1999-02-02 2001-10-16 Ortho-Clinical Diagnostics, Inc. Oligonucleotide reverse transcription primers for efficient detection of HIV-1 and HIV-2 and methods of use thereof
DE60041489D1 (de) * 1999-07-09 2009-03-19 Gen Probe Inc Nachweis von hiv-1 durch amplifizierung von nukleinsäuren
WO2001047955A2 (en) * 1999-12-23 2001-07-05 Medical Research Council Improvements in or relating to immune responses to hiv
AU2001233513A1 (en) * 2000-02-04 2001-08-14 K.U. Leuven Research And Development Hiv-1 resistance assay
US6582920B2 (en) 2000-09-01 2003-06-24 Gen-Probe Incorporated Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations
JP2002125687A (ja) * 2000-10-30 2002-05-08 Tosoh Corp Hiv−1検出のためのオリゴヌクレオチドおよび検出法
CA2547750C (en) * 2003-12-19 2014-04-08 Gen-Probe Incorporated Compositions, methods and kits for detecting the nucleic acids of hiv-1 and hiv-2
US20060292558A1 (en) * 2004-07-19 2006-12-28 Cell Biosciences Inc. Methods and apparatus for protein assay diagnostics
JP5073491B2 (ja) * 2004-07-19 2012-11-14 プロテインシンプル 分析対象物の検出のための方法
US7846676B2 (en) * 2004-07-19 2010-12-07 Cell Biosciences, Inc. Methods and devices for analyte detection
US7935479B2 (en) * 2004-07-19 2011-05-03 Cell Biosciences, Inc. Methods and devices for analyte detection
US8945361B2 (en) 2005-09-20 2015-02-03 ProteinSimple Electrophoresis standards, methods and kits
EP2025762A3 (en) 2006-01-17 2009-09-30 Health Research Inc. Heteroduplex tracking assay
US20080086118A1 (en) * 2006-05-17 2008-04-10 Applied Harmonics Corporation Apparatus and method for diode-pumped laser ablation of soft tissue
US20080017512A1 (en) * 2006-07-24 2008-01-24 Bordunov Andrei V Coatings for capillaries capable of capturing analytes
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
US10107782B2 (en) 2008-01-25 2018-10-23 ProteinSimple Method to perform limited two dimensional separation of proteins and other biologicals
JPWO2009122591A1 (ja) * 2008-04-04 2011-07-28 国立大学法人 琉球大学 ウイルス抗原及びウイルス抗体を一度に検出可能なウイルス抗原及びウイルス抗体の検出キット、並びにウイルス抗原及びウイルス抗体の検出方法
JPWO2009122592A1 (ja) * 2008-04-04 2011-07-28 国立大学法人 琉球大学 常温保存可能な試薬を備えたウイルス抗原及びウイルス抗体の検出キット、並びにウイルス抗原及びウイルス抗体の検出方法
WO2009126517A2 (en) * 2008-04-09 2009-10-15 Intelligent Medical Devices, Inc. Optimized probes and primers and methods of using same for the detection, quantification and grouping of hiv-1
US20120135397A1 (en) * 2009-07-07 2012-05-31 Tan Tock Seng Hospital Human immunodeficiency virus type 1 (hiv-1) detection method and kit therefor
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
JP2013523175A (ja) 2010-04-14 2013-06-17 イーエムディー・ミリポア・コーポレーション 高力価、高純度のウイルスストックの作製方法及びその使用方法
EP2707496A1 (en) 2011-05-11 2014-03-19 Diagon Kft. Procedure for rapid determination of viruses using nucleic acid-based molecular diagnostics, and a kit for this purpose
SMT201800284T1 (it) 2011-06-10 2018-07-17 Univ Oregon Health & Science Glicoproteine cmv e vettori ricombinanti
EP2568289A3 (en) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
EP2586461A1 (en) 2011-10-27 2013-05-01 Christopher L. Parks Viral particles derived from an enveloped virus
EP2839276B1 (en) 2012-04-19 2018-06-27 ProteinSimple Dual wavelength isoelectric focusing for determining drug load in antibody drug conjugates
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
US9766206B2 (en) 2013-09-27 2017-09-19 ProteinSimple Apparatus, systems, and methods for capillary electrophoresis
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP4674985A3 (en) * 2015-04-24 2026-04-01 The Johns Hopkins University Compositions and methods related to characterizing proviral reservoirs
CN116064923A (zh) * 2022-01-27 2023-05-05 圣湘生物科技股份有限公司 检测hiv-1的组合物、试剂盒、方法及其用途

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705612A (en) * 1984-10-18 1998-01-06 Institut Pasteur And Centre National De La Recherche Scientifique NEF peptide encoded by human immunodefiency virus type 1 (HIV-1)
CA1341423C (en) * 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4629783A (en) * 1985-04-29 1986-12-16 Genetic Systems Corporation Synthetic antigen for the detection of AIDS-related disease
US4803156A (en) * 1985-09-11 1989-02-07 New York Blood Center Peptide-beta-lactamase conjugates for enzyme-linked immunoassays
DE3760912D1 (en) * 1986-01-22 1989-12-07 Pasteur Institut Retrovirus of the type hiv-2 capable of inducing aids, and the antigenic and nucleic acid components thereof
US5079342A (en) * 1986-01-22 1992-01-07 Institut Pasteur Cloned DNA sequences related to the entire genomic RNA of human immunodeficiency virus II (HIV-2), polypeptides encoded by these DNA sequences and use of these DNA clones and polypeptides in diagnostic kits
US6265149B1 (en) * 1986-01-22 2001-07-24 Institut Pasteur In vitro diagnostic methods and kits for the detection of HIV-2-specific antibodies
US5030714A (en) * 1986-06-23 1991-07-09 Institut Pasteur Variant of LAV viruses
US5034511A (en) * 1987-04-13 1991-07-23 Institut Pasteur Variant of LAV viruses
US5030449A (en) * 1988-07-21 1991-07-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Synthetic vaccine against AIDS virus
US5141867A (en) * 1987-02-02 1992-08-25 E. I. Du Pont De Nemours And Company Nucleotide sequence encoding a human immunodeficiency virus antigen
DE3887053T4 (de) * 1987-04-16 1994-09-08 Johnson & Johnson Stlv-iii-verwandte polypeptide, diagnosesysteme und testmethoden.
US5013548A (en) * 1987-09-08 1991-05-07 Duke University Production of antibodies to HIV
US5019510A (en) * 1987-10-28 1991-05-28 Institut Pasteur Isolation, molecular cloning and sequencing of an HIV-1 isolate from a Gabonese donor
US5312737A (en) * 1988-03-11 1994-05-17 Abbott Laboratories CKS method of HCV protein synthesis
EP0345375B1 (en) * 1988-06-09 1995-03-22 N.V. Innogenetics S.A. HIV-3 retrovirus and its use
US5223423A (en) * 1989-03-31 1993-06-29 United States Of America Characterization of replication competent human immunodeficiency type 2 proviral clone hiv-2sbl/isy
DE4002636A1 (de) * 1990-01-30 1991-08-01 Boehringer Mannheim Gmbh Expression von hiv1- und 2-polypeptiden und deren verwendung
US5013458A (en) * 1990-04-06 1991-05-07 Rdp Company Process and apparatus for pathogen reduction in waste
ES2115622T5 (es) * 1990-10-17 2003-03-16 Us Health Clones moleculares de hiv-1 y usos de los mismos.
FR2676071B1 (fr) * 1991-05-02 1994-11-18 Transgene Sa Nouveau variant gp160 non-clivable, soluble, de forme hybride.
JP3277045B2 (ja) * 1992-10-06 2002-04-22 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング Hiv−グループのレトロウイルスおよびその使用
US5304046A (en) * 1993-06-14 1994-04-19 Yang Gene Huang Fluid transport device
DE4405810A1 (de) * 1994-02-23 1995-08-24 Behringwerke Ag Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung

Also Published As

Publication number Publication date
US20030003443A1 (en) 2003-01-02
EP0591914B1 (de) 1998-12-09
JPH06225760A (ja) 1994-08-16
JP4029107B2 (ja) 2008-01-09
US20020155428A1 (en) 2002-10-24
JP3277045B2 (ja) 2002-04-22
DE59309207D1 (de) 1999-01-21
US20070105219A1 (en) 2007-05-10
US6277561B1 (en) 2001-08-21
AU677225B2 (en) 1997-04-17
US6773915B2 (en) 2004-08-10
US20030003442A1 (en) 2003-01-02
JP2000312592A (ja) 2000-11-14
US5840480A (en) 1998-11-24
US6528626B2 (en) 2003-03-04
US6551824B2 (en) 2003-04-22
JP3854604B2 (ja) 2006-12-06
US6531587B2 (en) 2003-03-11
US20030166915A1 (en) 2003-09-04
US20070264627A1 (en) 2007-11-15
US6531137B2 (en) 2003-03-11
EP0890642A3 (de) 2000-09-13
EP0591914B2 (de) 2010-02-10
DK0591914T4 (da) 2010-05-25
CA2107732C (en) 2003-04-08
JP4113318B2 (ja) 2008-07-09
ES2126620T3 (es) 1999-04-01
US5759770A (en) 1998-06-02
EP0890642A2 (de) 1999-01-13
AU4880093A (en) 1994-04-21
US5770427A (en) 1998-06-23
EP0591914A2 (de) 1994-04-13
EP0591914A3 (en) 1994-08-10
DK0591914T3 (da) 1999-08-16
ES2126620T5 (es) 2010-05-21
US20020172939A1 (en) 2002-11-21
CA2107732A1 (en) 1994-04-07
US20050053920A1 (en) 2005-03-10
JP2004187686A (ja) 2004-07-08
JP2006201185A (ja) 2006-08-03

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