ATE175965T1 - Amorphe form von aztreonam - Google Patents

Amorphe form von aztreonam

Info

Publication number: ATE175965T1
Authority: AT; Austria
Prior art keywords: amorphous form; aztreonam; methylethoxy; ami; imino
Prior art date: 1987-07-01

Application number

AT88110480T

Other languages

English (en)

Inventor

Sailesh Amilal Varia

George Eugene Reier

James Douglas Pipkin

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-01

Filing date

1988-06-30

Publication date

1999-02-15

1988-06-30 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1999-02-15 Application granted granted Critical

1999-02-15 Publication of ATE175965T1 publication Critical patent/ATE175965T1/de

Links

WZPBZJONDBGPKJ-UHFFFAOYSA-N Antibiotic SQ 26917 Natural products O=C1N(S(O)(=O)=O)C(C)C1NC(=O)C(=NOC(C)(C)C(O)=O)C1=CSC(N)=N1 WZPBZJONDBGPKJ-UHFFFAOYSA-N 0.000 title 1
WZPBZJONDBGPKJ-VEHQQRBSSA-N aztreonam Chemical compound O=C1N(S([O-])(=O)=O)[C@@H](C)[C@@H]1NC(=O)C(=N/OC(C)(C)C(O)=O)\C1=CSC([NH3+])=N1 WZPBZJONDBGPKJ-VEHQQRBSSA-N 0.000 title 1
229960003644 aztreonam Drugs 0.000 title 1
125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Materials For Medical Uses (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT88110480T 1987-07-01 1988-06-30 Amorphe form von aztreonam ATE175965T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US6839287A	1987-07-01	1987-07-01

Publications (1)

Publication Number	Publication Date
ATE175965T1 true ATE175965T1 (de)	1999-02-15

Family

ID=22082279

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88110480T ATE175965T1 (de)	1987-07-01	1988-06-30	Amorphe form von aztreonam

Country Status (9)

Country	Link
EP (1)	EP0297580B1 (de)
JP (1)	JP2701869B2 (de)
KR (1)	KR890002141A (de)
CN (1)	CN1028234C (de)
AT (1)	ATE175965T1 (de)
CA (1)	CA1339136C (de)
DE (1)	DE3856297T2 (de)
ES (1)	ES2127178T3 (de)
GR (1)	GR3029873T3 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN191492B (de) *	1999-05-25	2003-12-06	Ranbaxy Lab Ltd
EP1415987B1 (de)	2000-10-20	2007-02-28	Eisai R&D Management Co., Ltd.	Stickstoff-enthaltende aromatische ringverbindungen zur behandlung von tumorerkrankungen
US7138419B2 (en)	2000-12-27	2006-11-21	Corus Pharma, Inc.	Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
US6660249B2 (en)	2000-12-27	2003-12-09	Salus Pharma, Inc.	Inhalable dry powder aztreonam for treatment and prevention of pulmonary bacterial infections
US7214364B2 (en) *	2000-12-27	2007-05-08	Corus Pharma, Inc.	Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
EP1527072A1 (de)	2002-08-05	2005-05-04	Teva Gyogyszergyar Reszvenytarsasag	Herstellung von aztreonam
WO2004052333A1 (en) *	2002-12-11	2004-06-24	Pari Gmbh	Pharmaceutical compositions for the pulmonary delivery of aztreonam
EP1604665B1 (de)	2003-03-10	2011-05-11	Eisai R&D Management Co., Ltd.	C-kit kinase-hemmer
WO2004103999A1 (en)	2003-05-15	2004-12-02	TEVA Gyógyszergyár Részvénytársaság	AZTREONAM β POLYMORPH WITH VERY LOW RESIDUAL SOLVENT CONTENT
WO2005005424A1 (en) *	2003-07-02	2005-01-20	TEVA Gyógyszergyár Részvénytársaság	Aztreonam l-lysine and methods for the preparation thereof
KR100839554B1 (ko)	2003-12-25	2008-06-20	에자이 알앤드디 매니지먼트 가부시키가이샤	4-(3-클로로-4-(시클로프로필아미노카르보닐)아미노페녹시)-7-메톡시-6-퀴놀린카르복사미드의 염 또는 그 용매화물의결정 및 이들의 제조 방법
ATE428421T1 (de)	2004-09-17	2009-05-15	Eisai R&D Man Co Ltd	Medizinische zusammensetzung mit verbesserter stabilität und reduzierten gelierungseigenschaften
US7601832B2 (en)	2005-05-09	2009-10-13	Sicor, Inc.	Process for making aztreonam
US7550483B2 (en)	2005-06-23	2009-06-23	Eisai R&D Management Co., Ltd.	Amorphous salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide and process for preparing the same
AU2006260148B9 (en) *	2005-06-23	2009-09-17	Eisai R&D Managment Co., Ltd.	Amorphous salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)- 7-methoxy-6-quinolinecarboxamide and process for producing the same
EP1925676A4 (de)	2005-08-02	2010-11-10	Eisai R&D Man Co Ltd	Testverfahren für die wirkung eines vaskularisierungsinhibitors
WO2007136103A1 (ja)	2006-05-18	2007-11-29	Eisai R & D Management Co., Ltd.	甲状腺癌に対する抗腫瘍剤
KR101472600B1 (ko)	2006-08-28	2014-12-15	에자이 알앤드디 매니지먼트 가부시키가이샤	미분화형 위암에 대한 항종양제
EP2119707B1 (de)	2007-01-29	2015-01-14	Eisai R&D Management Co., Ltd.	Zusammensetzung zur behandlung von nicht differenzierten formen von magenkrebsen
CN101848895B (zh)	2007-11-09	2013-10-23	卫材R&D管理有限公司	血管新生抑制物质和抗肿瘤性铂络合物的组合使用
CN101579336B (zh) *	2009-07-07	2010-06-23	重庆市庆余堂制药有限公司	一种注射用氨曲南及其生产方法
BR112012003592B8 (pt)	2009-08-19	2021-05-25	Eisai R&D Man Co Ltd	composição farmacêutica contendo derivado de quinolina
CA2802644C (en)	2010-06-25	2017-02-21	Eisai R & D Management Co., Ltd.	Antitumor agent using compounds having kinase inhibitory effect in combination
CN101912356B (zh) *	2010-08-02	2012-01-11	王明	一种氨曲南/精氨酸药物组合物脂微球注射剂
EP2700403B1 (de)	2011-04-18	2015-11-25	Eisai R&D Management Co., Ltd.	Therapeutikum für tumor
WO2012166899A2 (en)	2011-06-03	2012-12-06	Eisai R&D Management Co., Ltd.	Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
AU2013364953A1 (en) *	2012-12-21	2015-04-30	Eisai R&D Management Co., Ltd.	Amorphous form of quinoline derivative, and method for producing same
CN105264380B (zh)	2013-05-14	2017-09-05	卫材R&D管理有限公司	用于预测和评价子宫内膜癌受试者对乐伐替尼化合物响应性的生物标志
CA2957005C (en)	2014-08-28	2021-10-12	Eisai R&D Management Co., Ltd.	High-purity quinoline derivative and method for manufacturing same
SG11201706630UA (en)	2015-02-25	2017-09-28	Eisai R&D Man Co Ltd	Method for suppressing bitterness of quinoline derivative
WO2016140717A1 (en)	2015-03-04	2016-09-09	Merck Sharp & Dohme Corp.	Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer
BR112017027227B1 (pt)	2015-06-16	2023-12-12	Eisai R&D Management Co., Ltd	Agente anti-câncer
JP6553726B2 (ja)	2015-08-20	2019-07-31	エーザイ・アール・アンド・ディー・マネジメント株式会社	腫瘍治療剤
US12303505B2 (en)	2017-02-08	2025-05-20	Eisai R&D Management Co., Ltd.	Tumor-treating pharmaceutical composition
BR112019023064A2 (pt)	2017-05-16	2020-06-09	Eisai R&D Man Co Ltd	tratamento de carcinoma hepatocelular

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1181075A (en) *	1981-07-13	1985-01-15	David M. Floyd	CRYSTALLINE ANHYDROUS FORM OF [3-S-[3.alpha.(Z),4 .beta.]]-3-[[(2-AMINO-4-THIAZOLYL) [(1-CARBOXY-1-METHYLETHOXY)IMINO]ACETYL] AMINO]-4-METHYL-2-OXO-1-AZETIDINESULFONIC ACID
YU44680B (en) *	1982-07-30	1990-12-31	Glaxo Lab Ltd	Process for obtaining very pure amorphous form of cephuroxim axetile

1988
- 1988-06-28 CA CA000570624A patent/CA1339136C/en not_active Expired - Fee Related
- 1988-06-29 JP JP63162369A patent/JP2701869B2/ja not_active Expired - Lifetime
- 1988-06-29 CN CN88104073A patent/CN1028234C/zh not_active Expired - Fee Related
- 1988-06-30 ES ES88110480T patent/ES2127178T3/es not_active Expired - Lifetime
- 1988-06-30 AT AT88110480T patent/ATE175965T1/de not_active IP Right Cessation
- 1988-06-30 KR KR1019880007972A patent/KR890002141A/ko not_active Ceased
- 1988-06-30 DE DE3856297T patent/DE3856297T2/de not_active Expired - Fee Related
- 1988-06-30 EP EP88110480A patent/EP0297580B1/de not_active Expired - Lifetime
1999
- 1999-04-05 GR GR990400962T patent/GR3029873T3/el unknown

Also Published As

Publication number	Publication date
GR3029873T3 (en)	1999-07-30
JP2701869B2 (ja)	1998-01-21
DE3856297T2 (de)	1999-06-02
EP0297580A1 (de)	1989-01-04
DE3856297D1 (de)	1999-03-04
CN1028234C (zh)	1995-04-19
ES2127178T3 (es)	1999-04-16
CN1030238A (zh)	1989-01-11
KR890002141A (ko)	1989-04-08
EP0297580B1 (de)	1999-01-20
JPS6422874A (en)	1989-01-25
CA1339136C (en)	1997-07-29

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Legal Events

Date	Code	Title	Description
1999-11-15	UEP	Publication of translation of european patent specification
2001-03-15	REN	Ceased due to non-payment of the annual fee