BRPI0411691A - l-lisina de aztreonam e seus métodos de preparação - Google Patents

l-lisina de aztreonam e seus métodos de preparação

Info

Publication number
BRPI0411691A
BRPI0411691A BRPI0411691-7A BRPI0411691A BRPI0411691A BR PI0411691 A BRPI0411691 A BR PI0411691A BR PI0411691 A BRPI0411691 A BR PI0411691A BR PI0411691 A BRPI0411691 A BR PI0411691A
Authority
BR
Brazil
Prior art keywords
aztreonam
lysine
preparation methods
methods
lysine salt
Prior art date
Application number
BRPI0411691-7A
Other languages
English (en)
Inventor
Viktor Gyollai
Csaba Szabo
Claude Singer
Istvan Bodi
Original Assignee
Teva Gyogyszergyar Reszvenytar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Gyogyszergyar Reszvenytar filed Critical Teva Gyogyszergyar Reszvenytar
Publication of BRPI0411691A publication Critical patent/BRPI0411691A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"L-LISINA DE AZTREONAM E SEUS MéTODOS DE PREPARAçãO". A presente invenção está relacionada ao sal L-lisina de aztreonam e aos métodos para a preparação do sal L-lisina de aztreonam.
BRPI0411691-7A 2003-07-02 2004-07-01 l-lisina de aztreonam e seus métodos de preparação BRPI0411691A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48486103P 2003-07-02 2003-07-02
US55009804P 2004-03-04 2004-03-04
PCT/US2004/021237 WO2005005424A1 (en) 2003-07-02 2004-07-01 Aztreonam l-lysine and methods for the preparation thereof

Publications (1)

Publication Number Publication Date
BRPI0411691A true BRPI0411691A (pt) 2006-12-26

Family

ID=34068199

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0411691-7A BRPI0411691A (pt) 2003-07-02 2004-07-01 l-lisina de aztreonam e seus métodos de preparação

Country Status (10)

Country Link
US (2) US7262293B2 (pt)
JP (1) JP4741487B2 (pt)
AU (1) AU2004256124B2 (pt)
BR (1) BRPI0411691A (pt)
CA (2) CA2531170C (pt)
DE (1) DE112004001191B4 (pt)
ES (1) ES2304078B2 (pt)
IL (1) IL172802A (pt)
NO (1) NO333985B1 (pt)
WO (1) WO2005005424A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7214364B2 (en) 2000-12-27 2007-05-08 Corus Pharma, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
US7138419B2 (en) * 2000-12-27 2006-11-21 Corus Pharma, Inc. Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
DK2301524T3 (da) 2000-12-27 2013-07-15 Gilead Sciences Inc Inhalerbar aztreonam uden arginin til behandling og forebyggelse af bakterielle lungeinfektioner
MXPA05001486A (es) * 2002-08-05 2006-05-25 Teva Gyogyszergyar Reszvenytar Preparacion de aztreonam.
US7452991B2 (en) * 2003-05-15 2008-11-18 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Aztreonam β polymorph with very low residual solvent content
BRPI0411691A (pt) * 2003-07-02 2006-12-26 Teva Gyogyszergyar Reszvenytar l-lisina de aztreonam e seus métodos de preparação
AU2014271333B2 (en) * 2003-07-03 2016-10-27 Gilead Sciences, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
WO2006122253A1 (en) * 2005-05-09 2006-11-16 Sicor, Inc. Process for making aztreonam
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
CN110898040B (zh) * 2018-09-18 2022-05-17 北京盈科瑞创新药物研究有限公司 一种吸入用氨曲南溶液用冻干粉及其制备方法

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US4923998A (en) * 1977-03-14 1990-05-08 Fujisawa Pharmaceutical Company, Ltd. Cephem and cepham compounds and processes for preparation thereof
US4775670A (en) 1980-09-29 1988-10-04 E. R. Squibb & Sons, Inc. 2-oxo-1-azetidinesulfonic acid salts
US4529698A (en) * 1981-01-19 1985-07-16 E. R. Squibb & Sons, Inc. Process for preparing a 2-oxo-1-azetidinesulfonic acid salt
US4946838A (en) * 1981-07-13 1990-08-07 E. R. Squibb & Sons, Inc. Crystalline anhydrous aztreonam
CA1181075A (en) 1981-07-13 1985-01-15 David M. Floyd CRYSTALLINE ANHYDROUS FORM OF [3-S-[3.alpha.(Z),4 .beta.]]-3-[[(2-AMINO-4-THIAZOLYL) [(1-CARBOXY-1-METHYLETHOXY)IMINO]ACETYL] AMINO]-4-METHYL-2-OXO-1-AZETIDINESULFONIC ACID
US4652651A (en) * 1983-05-31 1987-03-24 Hoffmann-La Roche Inc. Process for the manufacture of 1-sulpho-2-oxoazetidine carboxylic acid intermediates via catalytic ester cleavage
US4826973A (en) * 1984-07-20 1989-05-02 E. R. Squibb & Sons, Inc. Delta form of aztreonam and preparation thereof
US4675398A (en) 1985-08-16 1987-06-23 E. R. Squibb & Sons, Inc. Copper-mediated oximation reaction
CA1339136C (en) * 1987-07-01 1997-07-29 Sailesh Amilal Varia Amorphous form of aztreonam
JP2653856B2 (ja) * 1988-11-08 1997-09-17 科学技術振興事業団 アミノ酸過酸化物の測定方法及び測定装置
US5254681A (en) * 1989-08-02 1993-10-19 Consiglio Nazionale Delle Ricerche Process for preparing monobactames and their intermediate product
US5194604A (en) * 1990-06-29 1993-03-16 E. R. Squibb & Sons, Inc. Process and intermediates for beta-lactams having aminothiazole(iminooxyacetic acid)acetic acid sidechains
PL165700B1 (pl) 1991-10-15 1995-01-31 Pan Sposób wytwarzania kwasu 32/2-amtnotiazoiilo-4/-2/1 -t-butoksykarbonylo- 1 -metyloetoksylmino/octowego
DE19652284A1 (de) * 1996-12-16 1998-06-18 Hoechst Schering Agrevo Gmbh Neue Gene codierend für Aminosäure-Deacetylasen mit Spezifität für N-Acetyl-L-Phosphinothricin, ihre Isolierung und Verwendung
AU4143200A (en) * 1999-04-27 2000-11-10 Masayoshi Nanba Human cell line showing stable expression of cytochromes p450
JP4320922B2 (ja) * 1999-06-04 2009-08-26 住友化学株式会社 エステラーゼ遺伝子及びその利用
AU1572101A (en) 1999-11-08 2001-06-06 Pharmacia & Upjohn Company Admixture of linezolid and other antibacterial agents
AUPQ872300A0 (en) * 2000-07-11 2000-08-03 Praxis Pharmaceuticals Pty Ltd Compounds and methods
US7214364B2 (en) * 2000-12-27 2007-05-08 Corus Pharma, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
US7138419B2 (en) * 2000-12-27 2006-11-21 Corus Pharma, Inc. Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
DK2301524T3 (da) * 2000-12-27 2013-07-15 Gilead Sciences Inc Inhalerbar aztreonam uden arginin til behandling og forebyggelse af bakterielle lungeinfektioner
UA75407C2 (en) * 2001-06-29 2006-04-17 Lundbeck & Co As H Heteroaryl derivatives of pyridine and pyrimidine, pharmaceutical composition and use thereof
CN1545514A (zh) 2001-08-27 2004-11-10 阿拉宾度药业有限公司 β型晶体无水氨曲南的生产方法
ATE363278T1 (de) * 2001-09-14 2007-06-15 Novo Nordisk As Neue liganden für die hisb10 zn2+ stellen des insulin-hexamers in der r-konformation
JP4460292B2 (ja) * 2001-10-17 2010-05-12 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト ピリミジン誘導体、これらの化合物を含む医薬組成物、その使用及びその調製方法
JP2005508220A (ja) * 2001-10-24 2005-03-31 パーリ・ゲーエムベーハー 薬用組成物調製用具
RU2004116911A (ru) * 2001-11-03 2005-11-10 Астразенека Аб (Se) Производные хиназолина в качестве противоопухолевых средств
CN1596114A (zh) * 2001-11-13 2005-03-16 三维药物公司 取代的1,4－苯并二氮杂䓬类及其在治疗癌症中的应用
MXPA05001486A (es) * 2002-08-05 2006-05-25 Teva Gyogyszergyar Reszvenytar Preparacion de aztreonam.
EP1413603A1 (en) 2002-10-25 2004-04-28 Titecs Japan Corporation Vibration-damping material composition
EP1417958A1 (en) * 2002-11-08 2004-05-12 Pari GmbH Wet granulation process
WO2004052333A1 (en) * 2002-12-11 2004-06-24 Pari Gmbh Pharmaceutical compositions for the pulmonary delivery of aztreonam
US7452991B2 (en) * 2003-05-15 2008-11-18 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Aztreonam β polymorph with very low residual solvent content
BRPI0411691A (pt) * 2003-07-02 2006-12-26 Teva Gyogyszergyar Reszvenytar l-lisina de aztreonam e seus métodos de preparação

Also Published As

Publication number Publication date
WO2005005424B1 (en) 2005-04-14
CA2531170A1 (en) 2005-01-20
AU2004256124B2 (en) 2011-04-28
JP2007521306A (ja) 2007-08-02
DE112004001191B4 (de) 2017-11-09
US7262293B2 (en) 2007-08-28
NO333985B1 (no) 2013-11-04
JP4741487B2 (ja) 2011-08-03
DE112004001191T5 (de) 2009-04-23
AU2004256124A1 (en) 2005-01-20
ES2304078A1 (es) 2008-09-01
US20050032775A1 (en) 2005-02-10
IL172802A0 (en) 2006-06-11
CA2531170C (en) 2011-05-10
IL172802A (en) 2011-10-31
CA2733145A1 (en) 2005-01-20
NO20060535L (no) 2006-02-01
WO2005005424A1 (en) 2005-01-20
CA2733145C (en) 2012-06-19
US20070167424A1 (en) 2007-07-19
ES2304078B2 (es) 2009-09-16
US7358093B2 (en) 2008-04-15

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]