ATE175967T1 - Verfahren zur herstellung von 2-amino-6- halogenopurin und synthese einer zwischenverbindung - Google Patents
Verfahren zur herstellung von 2-amino-6- halogenopurin und synthese einer zwischenverbindungInfo
- Publication number
- ATE175967T1 ATE175967T1 AT92114879T AT92114879T ATE175967T1 AT E175967 T1 ATE175967 T1 AT E175967T1 AT 92114879 T AT92114879 T AT 92114879T AT 92114879 T AT92114879 T AT 92114879T AT E175967 T1 ATE175967 T1 AT E175967T1
- Authority
- AT
- Austria
- Prior art keywords
- halogenopurine
- amino
- producing
- synthesis
- intermediate compound
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 4
- 230000015572 biosynthetic process Effects 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000003786 synthesis reaction Methods 0.000 title abstract 3
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33405391 | 1991-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE175967T1 true ATE175967T1 (de) | 1999-02-15 |
Family
ID=18272987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92114879T ATE175967T1 (de) | 1991-11-22 | 1992-08-31 | Verfahren zur herstellung von 2-amino-6- halogenopurin und synthese einer zwischenverbindung |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US5391733A (de) |
| EP (1) | EP0543095B1 (de) |
| KR (1) | KR0156265B1 (de) |
| AT (1) | ATE175967T1 (de) |
| AU (1) | AU653052B2 (de) |
| CA (1) | CA2076886C (de) |
| DE (1) | DE69228226T2 (de) |
| DK (1) | DK0543095T3 (de) |
| ES (1) | ES2128332T3 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9102127D0 (en) * | 1991-01-31 | 1991-03-13 | Smithkline Beecham Plc | Pharmaceuticals |
| CA2189088C (en) | 1995-11-09 | 2005-09-20 | Masatoshi Sakai | 2-amino-6-chloropurine and method for preparing the same |
| WO1998005663A1 (en) * | 1996-08-01 | 1998-02-12 | Sumika Fine Chemicals Co., Ltd. | Process for producing 2-amino-6-iodopurine |
| CN1161357C (zh) * | 2001-09-07 | 2004-08-11 | 浙江诚意药业有限公司 | 一种制备2,6-二氯嘌呤的方法 |
| US7307167B2 (en) | 2002-04-04 | 2007-12-11 | Sumitomo Chemical Company, Limited | Production method of 2,6-dihalopurine |
| CN108084184A (zh) * | 2017-12-25 | 2018-05-29 | 中山市得高行知识产权中心(有限合伙) | 一种2-氨基-6-氯嘌呤的合成方法 |
| CN108892669B (zh) * | 2018-08-01 | 2020-04-21 | 江苏八巨药业有限公司 | 一种制备2-氨基-6-氯嘌呤的方法 |
| CN114437071A (zh) * | 2022-01-12 | 2022-05-06 | 甘肃欣睿泽医药科技有限公司 | 嘌呤类衍生物的制备工艺 |
| CN114621228B (zh) * | 2022-04-19 | 2023-06-30 | 杭州丰禾生物技术有限公司 | 一种2-氨基-6-氯嘌呤的制备方法 |
| CN117466895A (zh) * | 2023-10-30 | 2024-01-30 | 江苏八巨药业有限公司 | 一种2-氨基-6-氯嘌呤的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB767216A (en) * | 1954-05-27 | 1957-01-30 | Burroughs Wellcome Co | Improvements in and relating to the preparation of purine derivatives |
| JPS5836915A (ja) * | 1981-08-27 | 1983-03-04 | Showa Denko Kk | SiC系物質の連続製造法 |
| EP0141927B1 (de) * | 1983-08-18 | 1991-10-30 | Beecham Group Plc | Antivirale Guanin-Derivate |
| US4621140A (en) * | 1984-02-23 | 1986-11-04 | Syntex (U.S.A.) Inc. | Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxymethyl)-purines and certain derivatives |
| ZA857647B (en) * | 1984-10-12 | 1986-05-28 | Warner Lambert Co | Purine derivatives |
| GB8507606D0 (en) * | 1985-03-23 | 1985-05-01 | Beecham Group Plc | Process |
| GB8817607D0 (en) * | 1988-07-23 | 1988-09-01 | Beecham Group Plc | Novel process |
| DE3941657A1 (de) * | 1989-12-16 | 1991-06-20 | Hoechst Ag | Verfahren zur herstellung von 2-acylamino-6-halogen-purin aus 2,9-diacylguanin |
| GB9102127D0 (en) * | 1991-01-31 | 1991-03-13 | Smithkline Beecham Plc | Pharmaceuticals |
| JP3432021B2 (ja) * | 1994-11-08 | 2003-07-28 | ホシザキ電機株式会社 | 飲料ディスペンサー |
-
1992
- 1992-08-26 CA CA002076886A patent/CA2076886C/en not_active Expired - Lifetime
- 1992-08-28 AU AU21397/92A patent/AU653052B2/en not_active Ceased
- 1992-08-31 AT AT92114879T patent/ATE175967T1/de active
- 1992-08-31 EP EP92114879A patent/EP0543095B1/de not_active Expired - Lifetime
- 1992-08-31 DK DK92114879T patent/DK0543095T3/da active
- 1992-08-31 ES ES92114879T patent/ES2128332T3/es not_active Expired - Lifetime
- 1992-08-31 US US07/937,427 patent/US5391733A/en not_active Expired - Lifetime
- 1992-08-31 DE DE69228226T patent/DE69228226T2/de not_active Expired - Lifetime
- 1992-08-31 KR KR1019920015755A patent/KR0156265B1/ko not_active Expired - Fee Related
-
1993
- 1993-09-02 US US08/115,015 patent/US5389637A/en not_active Expired - Lifetime
-
1994
- 1994-10-26 US US08/329,272 patent/US5440037A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69228226T2 (de) | 1999-07-08 |
| US5389637A (en) | 1995-02-14 |
| CA2076886A1 (en) | 1993-05-23 |
| DE69228226D1 (de) | 1999-03-04 |
| US5391733A (en) | 1995-02-21 |
| KR0156265B1 (ko) | 1998-11-16 |
| KR930010036A (ko) | 1993-06-21 |
| AU2139792A (en) | 1993-05-27 |
| EP0543095A3 (en) | 1993-09-01 |
| EP0543095B1 (de) | 1999-01-20 |
| CA2076886C (en) | 2002-06-11 |
| US5440037A (en) | 1995-08-08 |
| ES2128332T3 (es) | 1999-05-16 |
| DK0543095T3 (da) | 1999-09-13 |
| AU653052B2 (en) | 1994-09-15 |
| EP0543095A2 (de) | 1993-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner |