ATE176156T1 - Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff - Google Patents

Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff

Info

Publication number
ATE176156T1
ATE176156T1 AT90904479T AT90904479T ATE176156T1 AT E176156 T1 ATE176156 T1 AT E176156T1 AT 90904479 T AT90904479 T AT 90904479T AT 90904479 T AT90904479 T AT 90904479T AT E176156 T1 ATE176156 T1 AT E176156T1
Authority
AT
Austria
Prior art keywords
antigen
disclosed
methods
acrosomal
contraceptive vaccine
Prior art date
Application number
AT90904479T
Other languages
English (en)
Inventor
John C Herr
Richard M Wright
Original Assignee
Univ Virginia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Virginia filed Critical Univ Virginia
Application granted granted Critical
Publication of ATE176156T1 publication Critical patent/ATE176156T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/811—Drug, bio-affecting and body treating compositions involving sex selection or contraception
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y10S530/852—Sperm

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT90904479T 1989-03-03 1990-03-02 Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff ATE176156T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31855189A 1989-03-03 1989-03-03
US07/481,491 US5436157A (en) 1989-03-03 1990-02-16 Human intra-acrosomal sperm antigen

Publications (1)

Publication Number Publication Date
ATE176156T1 true ATE176156T1 (de) 1999-02-15

Family

ID=26981546

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90904479T ATE176156T1 (de) 1989-03-03 1990-03-02 Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff

Country Status (11)

Country Link
US (1) US5436157A (de)
EP (1) EP0461177B1 (de)
JP (1) JPH04505008A (de)
AT (1) ATE176156T1 (de)
AU (1) AU649609B2 (de)
CA (1) CA2050910C (de)
DE (1) DE69032922T2 (de)
DK (1) DK0461177T3 (de)
ES (1) ES2130121T3 (de)
NO (1) NO312594B1 (de)
WO (1) WO1990009802A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5346990A (en) * 1987-04-08 1994-09-13 Cytogam, Inc. Sex-associated membrane proteins and methods for increasing the probability that offspring will be of a desired sex
US5605803A (en) * 1989-03-03 1997-02-25 University Of Virginia Alumni Patents Foundation Human sperm diagnostic
JP2651249B2 (ja) * 1989-09-27 1997-09-10 扶桑薬品工業 株式会社 精子の受精能試験具および試験法
FR2660069B1 (fr) * 1990-03-20 1994-03-04 Recherche Developpement Activ Co Procede pour la mise en evidence de la capacite d'un spermatozouide a subir la reaction acrosomale.
US5721348A (en) * 1990-12-14 1998-02-24 University Of Connecticut DNA encoding PH-20 proteins
EP0691851A1 (de) * 1994-01-03 1996-01-17 Mauno Sakari Reiala Ein verfahren zur herstellung einer substanz zur vermeidung der zellpenetration, und ein kontrazeptivum zur vermeidung der betrachtung, und ein impfstoff und medikament gegen thrombose, prostatitis und aids
WO1997027218A1 (en) * 1996-01-29 1997-07-31 U.S. Environmental Protection Agency Method for evaluating and affecting male fertility
US7211255B2 (en) 1996-01-29 2007-05-01 United States Of America The U.S. Environmental Protection Agency Contraceptives based on SP22 and SP22 antibodies
US5830472A (en) * 1996-06-28 1998-11-03 The University Of Virginia Patent Foundation Purified sperm surface antigen, monoclonal antibody therefor and applications therefor
US6258364B1 (en) 1996-06-28 2001-07-10 University Of Virginia Patent Foundation Purified sperm surface antigen, monoclonal antibody therefor and application therefor
GB9812534D0 (en) * 1998-06-10 1998-08-05 Medical Res Council Sperm protein
WO2000029443A1 (en) * 1998-11-13 2000-05-25 Euro-Celtique, S.A. Contraceptive antibody vaccines
GB9913556D0 (en) * 1999-06-11 1999-08-11 Zeneca Ltd Assays
WO2001030853A1 (en) * 1999-10-26 2001-05-03 Fuso Pharmaceutical Industries, Ltd. Antibody against rat postacrosome reaction sperm and utilization thereof
US20020081592A1 (en) * 2000-03-07 2002-06-27 Whitehead Institute For Biomedical Research Reproduction-specific genes
US6801270B2 (en) * 2000-06-26 2004-10-05 Reveo, Inc. Backlight for a liquid crystal display having high light-recycling efficiency
GB0114922D0 (en) * 2001-06-19 2001-08-08 Sec Dep Of The Home Department Improvements in and relating to identification and analysis
WO2005079243A2 (en) * 2004-02-06 2005-09-01 University Of Virginia Patent Foundation Compositions and methods for identifying sperm for forensic applications
FR2877575B1 (fr) * 2004-11-05 2012-11-16 Union Nationale Des Cooperatives Agricoles D Elevage Et D Insemination Animale Milieu protecteur pour semence
EP1991874A4 (de) 2006-02-13 2009-06-03 Us Environment Diagnostische kits zum nachweis von sp22 und sp22-antikörpern
US20100247552A1 (en) 2006-11-10 2010-09-30 Massachusetts Institute Of Technology Pak modulators
JP2010538645A (ja) * 2007-09-11 2010-12-16 アリックス インク 対象物を選別するための結合方法および装置
WO2009035621A1 (en) * 2007-09-13 2009-03-19 Arryx, Inc. Methods and apparatuses for sorting objects in forensic dna analysis and medical diagnostics
WO2014093417A1 (en) 2012-12-12 2014-06-19 University Of Virginia Patent Foundation Compositions and methods for regulating erythropoiesis
US9957548B2 (en) 2015-03-30 2018-05-01 General Electric Company Methods of capturing sperm nucleic acids
US10030241B2 (en) 2015-03-30 2018-07-24 General Electric Company Methods and kits for capturing sperm nucleic acids
US10384207B2 (en) 2015-07-21 2019-08-20 Neuro Probe Incorporated Assay apparatus and methods
US20210355199A1 (en) 2018-06-28 2021-11-18 University Of Virginia Patent Foundation Compositions and methods for detecting and regulating fibronectin-integrin interaction and signaling

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1239346A (en) * 1985-06-04 1988-07-19 National Institute Of Immunology Birth control vaccine
US4741998A (en) * 1985-06-05 1988-05-03 The University Of Virginia Alumni Patents Foundation Monoclonal antibody to MHS-5: a new probe for sexual assault analyses
US5047508A (en) * 1985-06-05 1991-09-10 The University Of Virginia Alumni Patents Foundation Monoclonal antibody to MHS-5; a new probe for sexual assault analysis
US4782136A (en) * 1986-12-01 1988-11-01 Northwestern University Synthetic peptide compounds producing anitbodies binding to human LDH-C.sub.
US5232834A (en) * 1989-03-15 1993-08-03 Fuso Pharmaceutical Industries, Ltd. Anti-human sperm antibody, and its production and use

Also Published As

Publication number Publication date
DK0461177T3 (da) 1999-09-13
EP0461177A1 (de) 1991-12-18
AU649609B2 (en) 1994-06-02
NO913428L (no) 1991-10-18
WO1990009802A1 (en) 1990-09-07
NO312594B1 (no) 2002-06-03
CA2050910C (en) 2002-12-03
AU5186290A (en) 1990-09-26
ES2130121T3 (es) 1999-07-01
JPH04505008A (ja) 1992-09-03
CA2050910A1 (en) 1990-09-04
EP0461177A4 (en) 1993-01-07
DE69032922D1 (de) 1999-03-11
EP0461177B1 (de) 1999-01-27
DE69032922T2 (de) 1999-09-30
US5436157A (en) 1995-07-25
NO913428D0 (no) 1991-09-02

Similar Documents

Publication Publication Date Title
DE69032922D1 (de) Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff
DE69733960D1 (de) Verwendung von antikörpen gegen cd45ro leukozytenantigen zur immunmodulation
DE69521794D1 (de) Zellen mit mehreren geänderten epitopen auf einem oberflächeantigen zur verwendung in transplantation
DK0612250T3 (da) Fremgangsmåder og præparater med relation til nyttige Moraxella catarrhalis-antigener
EP0350690A3 (de) Neutralisation der in vitro- und in vivo-toxischen Eigenschaften von TNF-alfa durch monoklonale Antikörper und die davon abgeleiteten Fragmente
ATE166230T1 (de) Verwendung von anti-icam antikörpern zur herstellung eines präparats für die behandlung von endotoxinschock
EA199900067A1 (ru) Очищенный поверхностный антиген сперматозоидов, моноклональное антитело для него и их применения
Ohmori et al. Prostaglandin E2 as a selective stimulator of antigen‐specific IgE response in murine lymphocytes
DK0476226T3 (da) Monoklonalt antistof mod humant IgE
DE3584872D1 (de) Verfahren zur herstellung von monoklonalen antikoerpern gegen hbsag.
Franko et al. Monoclonal antibody analysis of keratin expression in the central nervous system.
DE69015230D1 (de) Antikörper gegen menschliches Sperma, ihre Herstellung und Anwendung.
KR890016165A (ko) 수도모나스 아에루기노사(Pseudomonas aeruginosa)에 대한 모노클로날 항체, 이의 제조방법 및 용도
WO2002012535B1 (en) Use of anti-ceacam antibodies for stimulating b cells in the production of monoclonal antibodies or in immunotherapy
Bradley Immunoglobulins
JPS6445398A (en) Antithrombin-binding substance monoclonal antibody, hybridoma producing said antibody and method for purifying and measuring thrombin-binding substance utilizing said monoclonal antibody
FR2571146B1 (fr) Antigenes carcino-foetaux du pancreas humain et un procede de purification, antiserum contre ces antigenes et son procede de preparation et compositions diagnostiques les contenant
Liu et al. Cytotoxic effect of nephrotoxic serum on rat tissue culture.
JPS6287090A (ja) 培養株化細胞株
Gratecos et al. A new approach to monoclonal antibody production In vitro immunization with antigens on nitrocellulose using Drosphila myosin heavy chain as an example
Herr et al. Human intra-acrosomal sperm antigen
KR880001806A (ko) γ-인터페론의 제조방법과 그 용도
Castell Cytoskeletal autoantibodies
Shiraishi et al. Immunology: Diagnostic relevance of abortion-associated human embryonic antigen expressed on the cell surface of tumour promoter-treated Bloom syndrome cells
Imami et al. K21‐Antigen: A Molecule Shared by the Microenvironments of the Human Thymus and Germinal Centers

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee