ATE176156T1 - Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff - Google Patents

Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff

Info

Publication number
ATE176156T1
ATE176156T1 AT90904479T AT90904479T ATE176156T1 AT E176156 T1 ATE176156 T1 AT E176156T1 AT 90904479 T AT90904479 T AT 90904479T AT 90904479 T AT90904479 T AT 90904479T AT E176156 T1 ATE176156 T1 AT E176156T1
Authority
AT
Austria
Prior art keywords
antigen
disclosed
methods
acrosomal
contraceptive vaccine
Prior art date
Application number
AT90904479T
Other languages
English (en)
Inventor
John C Herr
Richard M Wright
Original Assignee
Univ Virginia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Virginia filed Critical Univ Virginia
Application granted granted Critical
Publication of ATE176156T1 publication Critical patent/ATE176156T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/23Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/811Drug, bio-affecting and body treating compositions involving sex selection or contraception
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/85Reproductive organs or embryos
    • Y10S530/852Sperm

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90904479T 1989-03-03 1990-03-02 Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff ATE176156T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31855189A 1989-03-03 1989-03-03
US07/481,491 US5436157A (en) 1989-03-03 1990-02-16 Human intra-acrosomal sperm antigen

Publications (1)

Publication Number Publication Date
ATE176156T1 true ATE176156T1 (de) 1999-02-15

Family

ID=26981546

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90904479T ATE176156T1 (de) 1989-03-03 1990-03-02 Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff

Country Status (11)

Country Link
US (1) US5436157A (de)
EP (1) EP0461177B1 (de)
JP (1) JPH04505008A (de)
AT (1) ATE176156T1 (de)
AU (1) AU649609B2 (de)
CA (1) CA2050910C (de)
DE (1) DE69032922T2 (de)
DK (1) DK0461177T3 (de)
ES (1) ES2130121T3 (de)
NO (1) NO312594B1 (de)
WO (1) WO1990009802A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5346990A (en) * 1987-04-08 1994-09-13 Cytogam, Inc. Sex-associated membrane proteins and methods for increasing the probability that offspring will be of a desired sex
US5605803A (en) * 1989-03-03 1997-02-25 University Of Virginia Alumni Patents Foundation Human sperm diagnostic
JP2651249B2 (ja) * 1989-09-27 1997-09-10 扶桑薬品工業 株式会社 精子の受精能試験具および試験法
FR2660069B1 (fr) * 1990-03-20 1994-03-04 Recherche Developpement Activ Co Procede pour la mise en evidence de la capacite d'un spermatozouide a subir la reaction acrosomale.
US5721348A (en) * 1990-12-14 1998-02-24 University Of Connecticut DNA encoding PH-20 proteins
AU5817094A (en) * 1994-01-03 1995-08-01 Mauno Sakari Reiala A method to produce a substance to inhibit cell penetration, and a contraceptive to prevent conception, and a thrombus, prostate and aids vaccine and medicine
US7211255B2 (en) 1996-01-29 2007-05-01 United States Of America The U.S. Environmental Protection Agency Contraceptives based on SP22 and SP22 antibodies
AU2005797A (en) * 1996-01-29 1997-08-20 U.S. Environmental Protection Agency Method for evaluating and affecting male fertility
US6258364B1 (en) 1996-06-28 2001-07-10 University Of Virginia Patent Foundation Purified sperm surface antigen, monoclonal antibody therefor and application therefor
US5830472A (en) * 1996-06-28 1998-11-03 The University Of Virginia Patent Foundation Purified sperm surface antigen, monoclonal antibody therefor and applications therefor
GB9812534D0 (en) * 1998-06-10 1998-08-05 Medical Res Council Sperm protein
AU753753B2 (en) * 1998-11-13 2002-10-24 Euro-Celtique S.A. Contraceptive antibody vaccines
GB9913556D0 (en) * 1999-06-11 1999-08-11 Zeneca Ltd Assays
JP4610149B2 (ja) * 1999-10-26 2011-01-12 扶桑薬品工業株式会社 ラット先体反応後精子に対する抗体およびその利用
WO2001066752A2 (en) * 2000-03-07 2001-09-13 Whitehead Institute For Biomedical Research Reproduction-specific genes
US6801270B2 (en) * 2000-06-26 2004-10-05 Reveo, Inc. Backlight for a liquid crystal display having high light-recycling efficiency
GB0114922D0 (en) * 2001-06-19 2001-08-08 Sec Dep Of The Home Department Improvements in and relating to identification and analysis
WO2005079243A2 (en) * 2004-02-06 2005-09-01 University Of Virginia Patent Foundation Compositions and methods for identifying sperm for forensic applications
FR2877575B1 (fr) * 2004-11-05 2012-11-16 Union Nationale Des Cooperatives Agricoles D Elevage Et D Insemination Animale Milieu protecteur pour semence
EP1991874A4 (de) 2006-02-13 2009-06-03 Us Environment Diagnostische kits zum nachweis von sp22 und sp22-antikörpern
US20110294782A1 (en) 2006-11-10 2011-12-01 Massachusetts Institute Of Technology Small molecule pak inhibitors
CN101795744A (zh) * 2007-09-11 2010-08-04 阿尔利克斯公司 用于分选物体的结合方法和仪器
WO2009035621A1 (en) * 2007-09-13 2009-03-19 Arryx, Inc. Methods and apparatuses for sorting objects in forensic dna analysis and medical diagnostics
US20150329639A1 (en) 2012-12-12 2015-11-19 University Of Virginia Patent Foundation Compositions and methods for regulating erythropoiesis
US9957548B2 (en) 2015-03-30 2018-05-01 General Electric Company Methods of capturing sperm nucleic acids
US10030241B2 (en) 2015-03-30 2018-07-24 General Electric Company Methods and kits for capturing sperm nucleic acids
US10384207B2 (en) 2015-07-21 2019-08-20 Neuro Probe Incorporated Assay apparatus and methods
US20210355199A1 (en) 2018-06-28 2021-11-18 University Of Virginia Patent Foundation Compositions and methods for detecting and regulating fibronectin-integrin interaction and signaling

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1239346A (en) * 1985-06-04 1988-07-19 National Institute Of Immunology Birth control vaccine
US5047508A (en) * 1985-06-05 1991-09-10 The University Of Virginia Alumni Patents Foundation Monoclonal antibody to MHS-5; a new probe for sexual assault analysis
US4741998A (en) * 1985-06-05 1988-05-03 The University Of Virginia Alumni Patents Foundation Monoclonal antibody to MHS-5: a new probe for sexual assault analyses
US4782136A (en) * 1986-12-01 1988-11-01 Northwestern University Synthetic peptide compounds producing anitbodies binding to human LDH-C.sub.
US5232834A (en) * 1989-03-15 1993-08-03 Fuso Pharmaceutical Industries, Ltd. Anti-human sperm antibody, and its production and use

Also Published As

Publication number Publication date
NO312594B1 (no) 2002-06-03
AU5186290A (en) 1990-09-26
DK0461177T3 (da) 1999-09-13
WO1990009802A1 (en) 1990-09-07
EP0461177A1 (de) 1991-12-18
NO913428D0 (no) 1991-09-02
NO913428L (no) 1991-10-18
JPH04505008A (ja) 1992-09-03
DE69032922T2 (de) 1999-09-30
EP0461177A4 (en) 1993-01-07
EP0461177B1 (de) 1999-01-27
US5436157A (en) 1995-07-25
CA2050910C (en) 2002-12-03
AU649609B2 (en) 1994-06-02
CA2050910A1 (en) 1990-09-04
ES2130121T3 (es) 1999-07-01
DE69032922D1 (de) 1999-03-11

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Legal Events

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