ATE176470T1 - Xanthinderivate - Google Patents
XanthinderivateInfo
- Publication number
- ATE176470T1 ATE176470T1 AT91917824T AT91917824T ATE176470T1 AT E176470 T1 ATE176470 T1 AT E176470T1 AT 91917824 T AT91917824 T AT 91917824T AT 91917824 T AT91917824 T AT 91917824T AT E176470 T1 ATE176470 T1 AT E176470T1
- Authority
- AT
- Austria
- Prior art keywords
- represents hydrogen
- different
- same
- xanthine derivatives
- formula
- Prior art date
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title abstract 2
- 229940083747 low-ceiling diuretics xanthine derivative Drugs 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 102000009346 Adenosine receptors Human genes 0.000 abstract 1
- 108050000203 Adenosine receptors Proteins 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Led Devices (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28017190 | 1990-10-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE176470T1 true ATE176470T1 (de) | 1999-02-15 |
Family
ID=17621294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91917824T ATE176470T1 (de) | 1990-10-18 | 1991-10-17 | Xanthinderivate |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0559893B1 (de) |
| AT (1) | ATE176470T1 (de) |
| CA (1) | CA2094270C (de) |
| DE (1) | DE69130869T2 (de) |
| ES (1) | ES2130138T3 (de) |
| WO (1) | WO1992006976A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5484920A (en) * | 1992-04-08 | 1996-01-16 | Kyowa Hakko Kogyo Co., Ltd. | Therapeutic agent for Parkinson's disease |
| CA2093403C (en) * | 1992-04-08 | 1999-08-10 | Fumio Suzuki | Therapeutic agent for parkinson's disease |
| CA2116967C (en) * | 1992-07-08 | 2003-08-19 | Fumio Suzuki | Antidepressants |
| TW252044B (de) * | 1992-08-10 | 1995-07-21 | Boehringer Ingelheim Kg | |
| JP2613355B2 (ja) * | 1992-09-28 | 1997-05-28 | 協和醗酵工業株式会社 | パーキンソン氏病治療剤 |
| CA2112031A1 (en) * | 1992-12-24 | 1994-06-25 | Fumio Suzuki | Xanthine derivatives |
| AU6781194A (en) * | 1993-05-03 | 1994-11-21 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists |
| ES2070087B1 (es) * | 1993-08-13 | 1996-02-16 | Pfizer | Derivados de indol |
| DE69526822T2 (de) * | 1994-02-23 | 2003-01-23 | Kyowa Hakko Kogyo K.K., Tokio/Tokyo | Xanthin-derivate |
| DE69834500T2 (de) | 1997-09-05 | 2007-05-03 | Kyowa Hakko Kogyo Co., Ltd. | Xanthinderivative zur behandlung von hirnischämie |
| CA2315736A1 (en) | 1998-01-05 | 1999-07-15 | Eisai Co., Ltd. | Purine compounds and adenosine a2 receptor antagonist as preventive or therapeutic for diabetes mellitus |
| ATE319452T1 (de) * | 1999-10-29 | 2006-03-15 | Kyowa Hakko Kogyo Kk | Arzneimittel gegen essstörungen |
| FR2804958B1 (fr) * | 2000-02-15 | 2005-07-08 | Hoechst Marion Roussel Inc | Derives de xanthine, leur procede de preparation et les intermediaires de ce procede, leur application comme medicament et les compositions pharmaceutiques les renfermant |
| ES2686123T3 (es) | 2002-01-28 | 2018-10-16 | Kyowa Hakko Kogyo Co., Ltd | Antagonistas del receptor A2A para su uso en el tratamiento de trastornos del movimiento |
| US20060122198A1 (en) * | 2003-06-27 | 2006-06-08 | Kyowa Hakko Kogyo Co., Ltd. | Antiepileptic agent |
| CA2554426C (en) | 2004-01-28 | 2012-10-16 | Kyowa Kirin Co., Ltd. | Agents for treating migraine |
| ES2273599B1 (es) | 2005-10-14 | 2008-06-01 | Universidad De Barcelona | Compuestos para el tratamiento de la fibrilacion auricular. |
| CA2670788A1 (en) * | 2006-12-01 | 2008-06-12 | Cv Therapeutics, Inc. | A2a adenosine receptor antagonists |
| MX2009006346A (es) * | 2006-12-22 | 2010-03-03 | Sanol Arznei Schwarz Gmbh | Derivados de 8-etinilxantina como antagonistas de receptores de a2a selectivos. |
| RU2477726C1 (ru) * | 2011-10-18 | 2013-03-20 | Общество С Ограниченной Ответственностью "Ньювак" (Ооо "Ньювак") | Замещенные феноксиуксусные кислоты, их эфиры и амиды, включающие 2,6-диоксо-2,3,6,7-тетрагидро-1н-пурин-8-иловый фрагмент, - антагонисты аденозинового a2a рецептора и их применение |
| CN110981876B (zh) * | 2018-12-21 | 2021-10-01 | 广东东阳光药业有限公司 | 8-取代的苯乙烯基黄嘌呤衍生物及其用途 |
| CN111072663B (zh) * | 2019-12-12 | 2021-10-01 | 广东东阳光药业有限公司 | 8-取代的苯乙烯基黄嘌呤衍生物及其用途 |
| CN111018856B (zh) * | 2019-12-12 | 2021-10-01 | 广东东阳光药业有限公司 | 8-取代的苯乙烯基黄嘌呤衍生物及其用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2988711B2 (ja) * | 1989-10-20 | 1999-12-13 | 協和醗酵工業株式会社 | 縮合プリン誘導体 |
-
1991
- 1991-10-17 WO PCT/JP1991/001420 patent/WO1992006976A1/ja not_active Ceased
- 1991-10-17 CA CA002094270A patent/CA2094270C/en not_active Expired - Fee Related
- 1991-10-17 AT AT91917824T patent/ATE176470T1/de not_active IP Right Cessation
- 1991-10-17 EP EP91917824A patent/EP0559893B1/de not_active Expired - Lifetime
- 1991-10-17 DE DE69130869T patent/DE69130869T2/de not_active Expired - Fee Related
- 1991-10-17 ES ES91917824T patent/ES2130138T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992006976A1 (en) | 1992-04-30 |
| ES2130138T3 (es) | 1999-07-01 |
| CA2094270A1 (en) | 1992-04-19 |
| DE69130869T2 (de) | 1999-06-10 |
| CA2094270C (en) | 1997-01-21 |
| EP0559893A4 (en) | 1994-07-06 |
| DE69130869D1 (en) | 1999-03-18 |
| EP0559893B1 (de) | 1999-02-03 |
| EP0559893A1 (de) | 1993-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |