ATE176661T1 - Verfahren zur herstellung der enantiomere der 2- (2-fluor-4-biphenyl)-propionsäure - Google Patents

Verfahren zur herstellung der enantiomere der 2- (2-fluor-4-biphenyl)-propionsäure

Info

Publication number: ATE176661T1
Authority: AT; Austria
Prior art keywords: biphenyl; fluoro; propionic acid; enantiomers; preparing
Prior art date: 1994-12-27

Application number

AT95120200T

Other languages

English (en)

Inventor

Claudio Pozzoli

Graziano Castaldi

Original Assignee

Zambon Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-27

Filing date

1995-12-20

Publication date

1999-02-15

1995-12-20 Application filed by Zambon Spa filed Critical Zambon Spa

1999-02-15 Application granted granted Critical

1999-02-15 Publication of ATE176661T1 publication Critical patent/ATE176661T1/de

Links

HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical compound C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
XBDQKXXYIPTUBI-UHFFFAOYSA-N Propionic acid Substances CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 2
229910052799 carbon Inorganic materials 0.000 abstract 1
IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical class O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT95120200T 1994-12-27 1995-12-20 Verfahren zur herstellung der enantiomere der 2- (2-fluor-4-biphenyl)-propionsäure ATE176661T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITMI942647A IT1271800B (it)	1994-12-27	1994-12-27	Processo di preparazione degli enantiomeri dell'acido 2- (2-fluoro- 4-bifenil) propionico

Publications (1)

Publication Number	Publication Date
ATE176661T1 true ATE176661T1 (de)	1999-02-15

Family

ID=11370084

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95120200T ATE176661T1 (de)	1994-12-27	1995-12-20	Verfahren zur herstellung der enantiomere der 2- (2-fluor-4-biphenyl)-propionsäure

Country Status (11)

Country	Link
US (1)	US5840964A (de)
EP (1)	EP0719755B1 (de)
JP (1)	JP3766463B2 (de)
AT (1)	ATE176661T1 (de)
CA (1)	CA2165043C (de)
CZ (1)	CZ342695A3 (de)
DE (1)	DE69507791T2 (de)
ES (1)	ES2129746T3 (de)
IL (1)	IL116342A (de)
IT (1)	IT1271800B (de)
NO (1)	NO304425B1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1705636A (zh) *	2002-11-12	2005-12-07	辉瑞产品公司	将取代的苄叉胺的顺式－反式混合物转化成纯顺式异构体的方法
JP2006028154A (ja) *	2004-06-14	2006-02-02	Sumitomo Chemical Co Ltd	光学活性化合物の製造方法
US20070185346A1 (en) *	2006-02-03	2007-08-09	Vaidya Niteen A	Kit for automated resolving agent selection and method thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4209638A (en) *	1977-03-08	1980-06-24	The Boots Company Limited	Preparation of therapeutic agents
IT1208109B (it) *	1983-11-23	1989-06-06	Alfa Chem Ital	Procedimento per la risoluzione ottica di acidi arilpropionici
IT1196332B (it) *	1984-11-20	1988-11-16	Secifarma Spa	Procedimento per la risoluzione dell'acido (+)-6-metossi-alfa-metil-2-naftalen acetico nei corrispondenti antipodi ottici
IT1196334B (it) *	1984-11-22	1988-11-16	Alfa Chem Ital	Processo per la risoluzione ottica di miscugli racemi di acidi alfanaftil-propionici
DE3814887C1 (de) *	1988-05-02	1989-09-21	Medice Chem.-Pharm. Fabrik Puetter Gmbh & Co Kg, 5860 Iserlohn, De
DE3824353A1 (de) *	1988-07-19	1990-01-25	Paz Arzneimittelentwicklung	Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren
IT1237798B (it) *	1989-10-20	1993-06-17	Zambon Spa	Processo per l'inversione stereochimica di (2s,3s)-2-ammino-3-fenil-1 ,3-propandioli nei corrispondenti enantiomeri (2r,3r).
DE4028906A1 (de) *	1990-09-12	1992-03-19	Paz Arzneimittelentwicklung	Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen

1994
- 1994-12-27 IT ITMI942647A patent/IT1271800B/it active IP Right Grant
1995
- 1995-12-12 CA CA002165043A patent/CA2165043C/en not_active Expired - Fee Related
- 1995-12-12 IL IL11634295A patent/IL116342A/xx not_active IP Right Cessation
- 1995-12-20 AT AT95120200T patent/ATE176661T1/de not_active IP Right Cessation
- 1995-12-20 DE DE69507791T patent/DE69507791T2/de not_active Expired - Lifetime
- 1995-12-20 EP EP95120200A patent/EP0719755B1/de not_active Expired - Lifetime
- 1995-12-20 ES ES95120200T patent/ES2129746T3/es not_active Expired - Lifetime
- 1995-12-21 CZ CZ953426A patent/CZ342695A3/cs unknown
- 1995-12-22 NO NO955259A patent/NO304425B1/no not_active IP Right Cessation
- 1995-12-22 US US08/577,377 patent/US5840964A/en not_active Expired - Lifetime
- 1995-12-27 JP JP34101095A patent/JP3766463B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ITMI942647A1 (it)	1996-06-27
ES2129746T3 (es)	1999-06-16
DE69507791T2 (de)	1999-10-14
JPH08253440A (ja)	1996-10-01
IL116342A (en)	1999-06-20
JP3766463B2 (ja)	2006-04-12
IL116342A0 (en)	1996-03-31
ITMI942647A0 (it)	1994-12-27
NO955259L (no)	1996-06-28
NO955259D0 (no)	1995-12-22
DE69507791D1 (de)	1999-03-25
IT1271800B (it)	1997-06-09
CA2165043A1 (en)	1996-06-28
EP0719755A1 (de)	1996-07-03
CA2165043C (en)	2007-01-30
NO304425B1 (no)	1998-12-14
CZ342695A3 (en)	1996-07-17
US5840964A (en)	1998-11-24
EP0719755B1 (de)	1999-02-10

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Legal Events

Date	Code	Title	Description
1999-10-15	UEP	Publication of translation of european patent specification
2002-09-15	REN	Ceased due to non-payment of the annual fee