ATE177114T1 - Polypeptide und daraus hergestellte, gegen hiv wirksame substanzen - Google Patents

Polypeptide und daraus hergestellte, gegen hiv wirksame substanzen

Info

Publication number
ATE177114T1
ATE177114T1 AT94929644T AT94929644T ATE177114T1 AT E177114 T1 ATE177114 T1 AT E177114T1 AT 94929644 T AT94929644 T AT 94929644T AT 94929644 T AT94929644 T AT 94929644T AT E177114 T1 ATE177114 T1 AT E177114T1
Authority
AT
Austria
Prior art keywords
pct
polypeptides
polypeptide
effective against
against hiv
Prior art date
Application number
AT94929644T
Other languages
English (en)
Inventor
Akiyoshi Matsumoto
Michinori Waki
Original Assignee
Seikagaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Co Ltd
Application granted granted Critical
Publication of ATE177114T1 publication Critical patent/ATE177114T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Length Measuring Devices Characterised By Use Of Acoustic Means (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT94929644T 1993-10-14 1994-10-12 Polypeptide und daraus hergestellte, gegen hiv wirksame substanzen ATE177114T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28034693 1993-10-14

Publications (1)

Publication Number Publication Date
ATE177114T1 true ATE177114T1 (de) 1999-03-15

Family

ID=17623732

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94929644T ATE177114T1 (de) 1993-10-14 1994-10-12 Polypeptide und daraus hergestellte, gegen hiv wirksame substanzen

Country Status (17)

Country Link
US (1) US5776899A (de)
EP (1) EP0677061B1 (de)
JP (1) JPH08504837A (de)
KR (1) KR100208873B1 (de)
CN (1) CN1038841C (de)
AT (1) ATE177114T1 (de)
AU (1) AU682405B2 (de)
CA (1) CA2151283A1 (de)
CZ (1) CZ287239B6 (de)
DE (1) DE69416824T2 (de)
FI (1) FI952900A0 (de)
HU (1) HU217442B (de)
NO (1) NO952321L (de)
NZ (1) NZ274560A (de)
RU (1) RU2136696C1 (de)
WO (1) WO1995010534A1 (de)
ZA (1) ZA948005B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5708145A (en) * 1993-07-20 1998-01-13 University Of California Immunglobulins reactive with protegrins
US5693486A (en) * 1993-07-20 1997-12-02 Intrabiotics DNA sequences encoding protegrins and protegrin analogs and their use in recombinant methods of producing protegrins
US5804558A (en) * 1993-07-20 1998-09-08 University Of California Protegrins
US6653442B1 (en) 1993-07-20 2003-11-25 Intrabiotics Pharmaceuticals, Inc. Protegrins
US6025326A (en) * 1995-07-07 2000-02-15 Intrabiotics Pharmaceuticals, Inc. Compositions and methods for the prevention and treatment of oral mucositis
US5994306A (en) * 1995-11-22 1999-11-30 Intrabiotics Pharmaceuticals, Inc. Fine-tuned protegrins
US5916872A (en) * 1996-07-24 1999-06-29 Intrabiotics Pharmaceuticals, Inc. Cyclic peptides having broad spectrum antimicrobial activity
WO1998016555A1 (en) * 1996-10-15 1998-04-23 Seikagaku Corporation Polypeptide transition metal salts and method of enhancing anti-hiv activity of polypeptide
AU6518698A (en) * 1997-03-28 1998-10-22 Seikagaku Corporation Novel anti-hiv complexes and medicinal compositions
IL147970A0 (en) * 1999-08-09 2002-09-12 Tripep Ab Pharmaceutical compositions containing tripeptides
US6337317B1 (en) * 2000-06-27 2002-01-08 The University Of British Columbia Antimicrobial peptides and methods of use thereof
RU2175973C1 (ru) * 2000-08-10 2001-11-20 Гепвитания Лимитед Способ получения тетрадекапептида
US8435939B2 (en) 2000-09-05 2013-05-07 Biokine Therapeutics Ltd. Polypeptide anti-HIV agent containing the same
DE60136373D1 (de) 2000-09-05 2008-12-11 Biokine Therapeutics Ltd Neue polypeptide und anti-hiv-arzneimittel, die diese enthalten
US6593455B2 (en) * 2001-08-24 2003-07-15 Tripep Ab Tripeptide amides that block viral infectivity and methods of use thereof
CN1100564C (zh) * 2001-08-29 2003-02-05 周根发 用于治疗hiv感染的药物、其组合物及其用途
WO2003024995A1 (en) * 2001-09-19 2003-03-27 Tripep Ab Molecules that block viral infectivity and methods of use thereof
KR100932520B1 (ko) * 2002-10-31 2009-12-17 박래옥 항암제 조성물
AU2003261723A1 (en) 2002-08-27 2004-03-19 Takeda Chemical Industries, Ltd. Cxcr4 antagonist and use thereof
JP4781621B2 (ja) * 2002-08-27 2011-09-28 バイオカイン セラピューティックス リミテッド Cxcr4拮抗薬およびその用途
JP4603891B2 (ja) * 2002-10-31 2010-12-22 パク,レ−オク 抗癌剤組成物
US20040132642A1 (en) * 2002-11-12 2004-07-08 Government Of The U.S.A., Represented By The Secretary, Dept. Of Health & Human Services Methods of inhibiting metastasis or growth of a tumor cell
US20050096319A1 (en) * 2003-02-21 2005-05-05 Balzarini Jan M.R. Identification of compounds that inhibit replication of human immunodeficiency virus
KR20050101221A (ko) * 2003-02-21 2005-10-20 트리펩 아베 Hiv 복제의 억제를 위한 글리신아미드 유도체
WO2004096839A1 (en) 2003-05-02 2004-11-11 Polyphor Ag Template-fixed beta-hairpin peptidomimetics with cxcr4 antagonizing activity
ES2616341T3 (es) 2006-03-10 2017-06-12 Peptcell Limited Péptidos de proteínas reguladoras o accesorias de VIH, composiciones y la utilización de las mismas
CN100366633C (zh) * 2006-04-18 2008-02-06 河北师范大学 棕点湍蛙抗病毒多肽及其在制药中的应用
WO2008075371A2 (en) 2006-12-21 2008-06-26 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for immunomodulation
US9271933B2 (en) * 2007-11-27 2016-03-01 Rutgers, The State University Of New Jersey Graft copolymer polyelectrolyte complexes for drug delivery
US9789194B2 (en) 2007-11-27 2017-10-17 Rutgers, The State University Of New Jersey Graft copolymer polyelectrolyte complexes for drug delivery
EP4071169A2 (de) 2008-08-25 2022-10-12 Dana Farber Cancer Institute, Inc. Konserviertes influenza-hemagglutinin-epitop und antikörper dafür
BRPI1009663A2 (pt) 2009-06-14 2016-10-11 Biokine Therapeutics Ltd "método para elevação dos níveis plaquetários em um indivíduo com essa necessidade, método de inibição de hemorragia em um indivíduo que a necessite e composição farmacêutica"
CN103703018B (zh) 2011-06-07 2016-10-26 波利弗尔股份公司 作为CXC4拮抗剂的β-发夹肽模拟物
EP2841084B1 (de) 2012-04-24 2018-05-30 Biokine Therapeutics Ltd. Cxcr4 antagonist peptid zur verwendung in der behandlung von lungenkrebs
CN104072579B (zh) * 2014-06-11 2017-01-25 南方医科大学 具有抗菌抗病毒活性的小分子肽及其活性修饰物
US10786547B2 (en) 2015-07-16 2020-09-29 Biokine Therapeutics Ltd. Compositions, articles of manufacture and methods for treating cancer
KR102033920B1 (ko) 2016-02-23 2019-10-18 바이오라인알엑스 리미티드 급성 골수성 백혈병을 치료하는 방법
RU2658781C1 (ru) * 2017-12-28 2018-06-22 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Пептид, обладающий противоопухолевой активностью
CN110841607B (zh) * 2019-11-22 2020-07-24 中国科学院地质与地球物理研究所 一种超低本底金特效树脂及其制备和应用
CN115490756A (zh) * 2021-06-18 2022-12-20 深圳市健翔生物制药有限公司 一种固液相结合制备依特卡肽的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337781C (en) * 1987-08-21 1995-12-19 Takanori Nakamura Polypeptide from horseshoe crab exhibiting affinity for lipopolysaccharide and method of preparation
JP2641742B2 (ja) * 1988-08-18 1997-08-20 マルハ株式会社 新規ペプチド及び抗菌剤
JP2641744B2 (ja) * 1988-08-18 1997-08-20 マルハ株式会社 新規ペプチド及び抗菌剤
JP2798711B2 (ja) * 1988-09-26 1998-09-17 生化学工業株式会社 ポリペプチド系抗ウィルス剤
FI922044A0 (fi) * 1990-09-11 1992-05-06 Seikagaku Kogyo Co Ltd Ny polypeptid och daerav framstaelld hiv-medicin.
JP3266311B2 (ja) * 1991-05-02 2002-03-18 生化学工業株式会社 新規ポリペプチドおよびこれを用いる抗hiv剤
HUT61036A (en) * 1991-05-02 1992-11-30 Seikagaku Kogyo Co Ltd Process for producing new polypeptides capable of linking to lipopolysaccharides and pharmaceutical compositions comprising same as active ingredients
JP2500194B2 (ja) 1993-08-10 1996-05-29 株式会社ヴァンドームヤマダ 商品発注システム

Also Published As

Publication number Publication date
HU9501719D0 (en) 1995-08-28
DE69416824D1 (de) 1999-04-08
NO952321D0 (no) 1995-06-13
NO952321L (no) 1995-08-09
DE69416824T2 (de) 1999-07-08
AU7862894A (en) 1995-05-04
CA2151283A1 (en) 1995-04-20
AU682405B2 (en) 1997-10-02
US5776899A (en) 1998-07-07
HUT72974A (en) 1996-06-28
WO1995010534A1 (en) 1995-04-20
CZ287239B6 (en) 2000-10-11
FI952900A7 (fi) 1995-06-13
EP0677061A1 (de) 1995-10-18
CN1116427A (zh) 1996-02-07
JPH08504837A (ja) 1996-05-28
CZ153395A3 (en) 1995-12-13
HU217442B (hu) 2000-01-28
NZ274560A (en) 1998-03-25
KR100208873B1 (ko) 1999-07-15
FI952900A0 (fi) 1995-06-13
RU2136696C1 (ru) 1999-09-10
ZA948005B (en) 1996-02-06
RU95112539A (ru) 1997-06-27
CN1038841C (zh) 1998-06-24
EP0677061B1 (de) 1999-03-03

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