ATE177745T1 - Herstellungungsverfahren von bamifyllin und etamiphyllin - Google Patents

Herstellungungsverfahren von bamifyllin und etamiphyllin

Info

Publication number: ATE177745T1
Authority: AT; Austria
Prior art keywords: pct; etamiphylline; bamifylline; sec; production process
Prior art date: 1993-01-21

Application number

AT94903710T

Other languages

English (en)

Inventor

Fernand Thyrion

Hong Yang

Michel Parmantier

Original Assignee

Nycomed Christiaens Nv Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-01-21

Filing date

1994-01-19

Publication date

1999-04-15

1994-01-19 Application filed by Nycomed Christiaens Nv Sa filed Critical Nycomed Christiaens Nv Sa

1999-04-15 Application granted granted Critical

1999-04-15 Publication of ATE177745T1 publication Critical patent/ATE177745T1/de

Links

229960005176 bamifylline Drugs 0.000 title abstract 2
VVUYEFBRTFASAH-UHFFFAOYSA-N bamifylline Chemical compound N=1C=2N(C)C(=O)N(C)C(=O)C=2N(CCN(CCO)CC)C=1CC1=CC=CC=C1 VVUYEFBRTFASAH-UHFFFAOYSA-N 0.000 title abstract 2
229960000505 etamiphylline Drugs 0.000 title abstract 2
AWKLBIOQCIORSB-UHFFFAOYSA-N etamiphylline Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2CCN(CC)CC AWKLBIOQCIORSB-UHFFFAOYSA-N 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 2
SWKGFZTXWQMFLK-UHFFFAOYSA-N 8-benzyl-1,3-dimethyl-7h-purine-2,6-dione Chemical compound N1C=2C(=O)N(C)C(=O)N(C)C=2N=C1CC1=CC=CC=C1 SWKGFZTXWQMFLK-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229960000278 theophylline Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT94903710T 1993-01-21 1994-01-19 Herstellungungsverfahren von bamifyllin und etamiphyllin ATE177745T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
BE9300059A BE1006613A3 (fr)	1993-01-21	1993-01-21	Procede de conversion de cycle xanthine ou derives de cycle xanthine en derives de type dialkylamino-xanthine.

Publications (1)

Publication Number	Publication Date
ATE177745T1 true ATE177745T1 (de)	1999-04-15

Family

ID=3886800

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94903710T ATE177745T1 (de)	1993-01-21	1994-01-19	Herstellungungsverfahren von bamifyllin und etamiphyllin

Country Status (6)

Country	Link
US (1)	US5739331A (de)
EP (1)	EP0680479B1 (de)
AT (1)	ATE177745T1 (de)
BE (1)	BE1006613A3 (de)
DE (1)	DE69417214D1 (de)
WO (1)	WO1994017064A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2006518390A (ja) *	2003-02-19	2006-08-10	エンダシア，インコーポレイテッド	Ａ１アデノシンレセプターアンタゴニスト
US7247639B2 (en) *	2003-06-06	2007-07-24	Endacea, Inc.	A1 adenosine receptor antagonists
WO2009086077A2 (en)	2007-12-21	2009-07-09	Endacea, Inc.	A1 adenosine receptor antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB947495A (en) *	1960-04-22	1964-01-22	Manuf Prod Pharma	New derivatives of dialkyl xanthines and the preparation thereof
US3309271A (en) *	1963-08-30	1967-03-14	Manuf Prod Pharma	Methods and composition for inducing choleresis
BE883654A (fr) *	1980-06-05	1980-12-05	Christiaens Sa A	Procede de preparation de bamifylline.

1993
- 1993-01-21 BE BE9300059A patent/BE1006613A3/fr not_active IP Right Cessation
1994
- 1994-01-19 EP EP94903710A patent/EP0680479B1/de not_active Expired - Lifetime
- 1994-01-19 AT AT94903710T patent/ATE177745T1/de not_active IP Right Cessation
- 1994-01-19 WO PCT/BE1994/000006 patent/WO1994017064A1/fr not_active Ceased
- 1994-01-19 DE DE69417214T patent/DE69417214D1/de not_active Expired - Lifetime
- 1994-01-19 US US08/492,046 patent/US5739331A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US5739331A (en)	1998-04-14
EP0680479B1 (de)	1999-03-17
DE69417214D1 (de)	1999-04-22
BE1006613A3 (fr)	1994-11-03
EP0680479A1 (de)	1995-11-08
WO1994017064A1 (fr)	1994-08-04

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Legal Events

Date	Code	Title	Description
1999-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties