ATE177745T1 - Herstellungungsverfahren von bamifyllin und etamiphyllin - Google Patents
Herstellungungsverfahren von bamifyllin und etamiphyllinInfo
- Publication number
- ATE177745T1 ATE177745T1 AT94903710T AT94903710T ATE177745T1 AT E177745 T1 ATE177745 T1 AT E177745T1 AT 94903710 T AT94903710 T AT 94903710T AT 94903710 T AT94903710 T AT 94903710T AT E177745 T1 ATE177745 T1 AT E177745T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- etamiphylline
- bamifylline
- sec
- production process
- Prior art date
Links
- 229960005176 bamifylline Drugs 0.000 title abstract 2
- VVUYEFBRTFASAH-UHFFFAOYSA-N bamifylline Chemical compound N=1C=2N(C)C(=O)N(C)C(=O)C=2N(CCN(CCO)CC)C=1CC1=CC=CC=C1 VVUYEFBRTFASAH-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000505 etamiphylline Drugs 0.000 title abstract 2
- AWKLBIOQCIORSB-UHFFFAOYSA-N etamiphylline Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2CCN(CC)CC AWKLBIOQCIORSB-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 2
- SWKGFZTXWQMFLK-UHFFFAOYSA-N 8-benzyl-1,3-dimethyl-7h-purine-2,6-dione Chemical compound N1C=2C(=O)N(C)C(=O)N(C)C=2N=C1CC1=CC=CC=C1 SWKGFZTXWQMFLK-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960000278 theophylline Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE9300059A BE1006613A3 (fr) | 1993-01-21 | 1993-01-21 | Procede de conversion de cycle xanthine ou derives de cycle xanthine en derives de type dialkylamino-xanthine. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE177745T1 true ATE177745T1 (de) | 1999-04-15 |
Family
ID=3886800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94903710T ATE177745T1 (de) | 1993-01-21 | 1994-01-19 | Herstellungungsverfahren von bamifyllin und etamiphyllin |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5739331A (de) |
| EP (1) | EP0680479B1 (de) |
| AT (1) | ATE177745T1 (de) |
| BE (1) | BE1006613A3 (de) |
| DE (1) | DE69417214D1 (de) |
| WO (1) | WO1994017064A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004074247A2 (en) * | 2003-02-19 | 2004-09-02 | Endacea, Inc. | A1 adenosine receptor antagonists |
| EP1636229A4 (de) * | 2003-06-06 | 2008-07-30 | Endacea Inc | A1-adenosinrezeptorantagonisten |
| US9522916B2 (en) | 2007-12-21 | 2016-12-20 | Constance Neely Wilson | A1 adenosine receptor antagonists |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB947495A (en) * | 1960-04-22 | 1964-01-22 | Manuf Prod Pharma | New derivatives of dialkyl xanthines and the preparation thereof |
| US3309271A (en) * | 1963-08-30 | 1967-03-14 | Manuf Prod Pharma | Methods and composition for inducing choleresis |
| BE883654A (fr) * | 1980-06-05 | 1980-12-05 | Christiaens Sa A | Procede de preparation de bamifylline. |
-
1993
- 1993-01-21 BE BE9300059A patent/BE1006613A3/fr not_active IP Right Cessation
-
1994
- 1994-01-19 WO PCT/BE1994/000006 patent/WO1994017064A1/fr not_active Ceased
- 1994-01-19 US US08/492,046 patent/US5739331A/en not_active Expired - Lifetime
- 1994-01-19 EP EP94903710A patent/EP0680479B1/de not_active Expired - Lifetime
- 1994-01-19 DE DE69417214T patent/DE69417214D1/de not_active Expired - Lifetime
- 1994-01-19 AT AT94903710T patent/ATE177745T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69417214D1 (de) | 1999-04-22 |
| US5739331A (en) | 1998-04-14 |
| EP0680479B1 (de) | 1999-03-17 |
| EP0680479A1 (de) | 1995-11-08 |
| WO1994017064A1 (fr) | 1994-08-04 |
| BE1006613A3 (fr) | 1994-11-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |