ATE178204T1 - Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer - Google Patents

Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer

Info

Publication number
ATE178204T1
ATE178204T1 AT95942772T AT95942772T ATE178204T1 AT E178204 T1 ATE178204 T1 AT E178204T1 AT 95942772 T AT95942772 T AT 95942772T AT 95942772 T AT95942772 T AT 95942772T AT E178204 T1 ATE178204 T1 AT E178204T1
Authority
AT
Austria
Prior art keywords
17beta
administration
intravaginal device
oestradiol precursor
oestradiol
Prior art date
Application number
AT95942772T
Other languages
English (en)
Inventor
Allen Mcclay
Original Assignee
Galen Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galen Chemicals Ltd filed Critical Galen Chemicals Ltd
Application granted granted Critical
Publication of ATE178204T1 publication Critical patent/ATE178204T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
AT95942772T 1994-12-19 1995-12-19 Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer ATE178204T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IES940976 1994-12-19
IES950247 1995-04-05

Publications (1)

Publication Number Publication Date
ATE178204T1 true ATE178204T1 (de) 1999-04-15

Family

ID=26319777

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95942772T ATE178204T1 (de) 1994-12-19 1995-12-19 Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer

Country Status (19)

Country Link
US (1) US5855906A (de)
EP (1) EP0799025B1 (de)
JP (1) JPH10510825A (de)
CN (1) CN1138526C (de)
AR (1) AR002010A1 (de)
AT (1) ATE178204T1 (de)
AU (1) AU692659B2 (de)
CA (1) CA2207622C (de)
DE (1) DE69508791T2 (de)
DK (1) DK0799025T3 (de)
ES (1) ES2133841T3 (de)
FI (1) FI119414B (de)
GR (1) GR3030614T3 (de)
IL (1) IL116433A (de)
NO (1) NO316707B1 (de)
NZ (1) NZ298490A (de)
PE (1) PE62796A1 (de)
TR (1) TR199501599A2 (de)
WO (1) WO1996019196A1 (de)

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US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6416780B1 (en) * 1997-05-07 2002-07-09 Galen (Chemicals) Limited Intravaginal drug delivery devices for the administration of testosterone and testosterone precursors
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US20050113351A1 (en) * 2000-03-21 2005-05-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20040176336A1 (en) * 2000-03-21 2004-09-09 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US6811549B2 (en) 2001-02-16 2004-11-02 William H. Fleming Administration of therapeutic or diagnostic agents using interlabial pad
US6962908B2 (en) * 2001-12-21 2005-11-08 Warner Chilcott Company Inc. Oral pharmaceutical products containing 17 β-estradiol-3-lower alkanoate, method of administering the same and process of preparation
WO2003080018A1 (en) * 2002-03-27 2003-10-02 Galen (Chemicals) Limited Intravaginal matrix drug delivery devices
GB0222522D0 (en) * 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
CA2523859C (en) * 2003-04-29 2011-08-02 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
US20060183724A1 (en) * 2005-02-03 2006-08-17 Diliberti Charles E Compositions of unconjugated estrogens and methods for their use
US20060185678A1 (en) * 2005-02-03 2006-08-24 Bronnenkant Lance J Devices for delivering agents to a vaginal tract
EP1933810B1 (de) * 2005-08-11 2012-10-10 Massachusetts Institute of Technology Vorrichtung und verfahren für intravesikale wirkstofffreisetzung
US20070077269A1 (en) * 2005-10-04 2007-04-05 Woodward John R Method of birth control and hormone regulation
AU2006304229A1 (en) 2005-10-13 2007-04-26 Synthes Gmbh Drug-impregnated encasement
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
EP2037938A2 (de) * 2006-07-12 2009-03-25 Controlled Therapeutics (Scotland) Ltd. Arzneiabgabe-polymer mit clindamycin-hydrochloridsalz
GB0620685D0 (en) * 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
EP2170276B1 (de) * 2007-06-26 2018-08-22 Allergan Pharmaceuticals International Limited Intravaginale arzneiabgabevorrichtungen zur abgabe von makromolekülen und wasserlöslichen arzneimitteln
JP5560200B2 (ja) 2007-12-11 2014-07-23 マサチューセッツ インスチテュート オブ テクノロジー 膀胱および他の身体の小嚢又は管腔を治療するための埋め込み型薬物供給デバイス
CN102176931B (zh) * 2008-08-09 2015-03-04 麻省理工学院 治疗男性泌尿生殖组织和外周组织的可植入药物递送设备和方法
AU2010256558B2 (en) 2009-06-03 2013-10-03 Forsight Labs, Llc Anterior segment drug delivery
ES2401008T3 (es) 2009-06-26 2013-04-16 Taris Biomedical, Inc. Comprimidos farmacéuticos sólidos para dispositivos implantables para la administración de fármacos
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
SG191893A1 (en) 2011-01-10 2013-08-30 Taris Biomedical Inc Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding
RU2598057C2 (ru) 2011-02-04 2016-09-20 ТАРИС Биомедикал ЛЛК Имплантируемое устройство для контролируемого высвобождения лекарственного средства с низкой растворимостью
KR102192603B1 (ko) 2011-09-14 2020-12-17 포사이트 비젼5, 인크. 안내 삽입물 장치 및 방법
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
RU2652063C2 (ru) 2012-10-26 2018-04-24 Форсайт Вижн5, Инк. Офтальмологическая система для замедленного высвобождения лекарственного средства в глазу
SG11201507294WA (en) 2013-03-15 2015-10-29 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
CA2916249C (en) 2013-06-21 2021-07-13 DePuy Synthes Products, Inc. Films and methods of manufacture
LT3035991T (lt) 2013-08-19 2020-11-10 Taris Biomedical Llc Daugiablokiai vaistų vartojimo įtaisai
CN104546668B (zh) * 2013-10-23 2019-03-05 国家卫生计生委科学技术研究所 液体硅橡胶为载体的药物缓控释系统的制备及应用
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
PT3125964T (pt) * 2014-04-01 2024-09-09 Poly Med Inc Contracetivo e dispositivo relacionado
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
EP3285850A1 (de) 2015-04-23 2018-02-28 TARIS Biomedical LLC Wirkstoffabgabevorrichtungen mit einer wirkstoffdurchlässigen komponente und verfahren
CN114573654B (zh) * 2020-12-01 2025-09-12 北京奇明达企业管理有限公司 17-O-乙酰-17-β雌二醇的自组装的三聚体、其制备、活性和应用

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US3545439A (en) * 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US4291014A (en) * 1979-01-11 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estradiol diacetate
US4438139A (en) * 1979-08-14 1984-03-20 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estrogens
SE8602666D0 (sv) * 1986-06-16 1986-06-16 Leo Ab Intravaginal devices

Also Published As

Publication number Publication date
GR3030614T3 (en) 1999-10-29
IL116433A0 (en) 1996-03-31
EP0799025A1 (de) 1997-10-08
WO1996019196A1 (en) 1996-06-27
CA2207622C (en) 2006-10-17
JPH10510825A (ja) 1998-10-20
CA2207622A1 (en) 1996-06-27
FI119414B (fi) 2008-11-14
US5855906A (en) 1999-01-05
AU4399196A (en) 1996-07-10
IL116433A (en) 2002-02-10
NO316707B1 (no) 2004-04-13
DK0799025T3 (da) 1999-10-18
AU692659B2 (en) 1998-06-11
DE69508791T2 (de) 1999-12-02
PE62796A1 (es) 1996-12-28
DE69508791D1 (de) 1999-05-06
NZ298490A (en) 1999-11-29
ES2133841T3 (es) 1999-09-16
NO972798D0 (no) 1997-06-17
FI972579L (fi) 1997-06-17
CN1170353A (zh) 1998-01-14
EP0799025B1 (de) 1999-03-31
NO972798L (no) 1997-08-19
FI972579A0 (fi) 1997-06-17
TR199501599A2 (tr) 1996-07-21
AR002010A1 (es) 1998-01-07
CN1138526C (zh) 2004-02-18

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