ATE178881T1 - Asymmetrische hydrierung von beta- oder gamma- ketoestern und von beta- oder gamma-ketoamiden - Google Patents

Asymmetrische hydrierung von beta- oder gamma- ketoestern und von beta- oder gamma-ketoamiden

Info

Publication number
ATE178881T1
ATE178881T1 AT95906761T AT95906761T ATE178881T1 AT E178881 T1 ATE178881 T1 AT E178881T1 AT 95906761 T AT95906761 T AT 95906761T AT 95906761 T AT95906761 T AT 95906761T AT E178881 T1 ATE178881 T1 AT E178881T1
Authority
AT
Austria
Prior art keywords
beta
gamma
ketoamids
asymmetric hydrogenation
keto esters
Prior art date
Application number
AT95906761T
Other languages
English (en)
Inventor
Joseph D Armstrong Iii
Lisa Dimichele
Alan W Douglas
Jennifer L Keller
Steven A King
Andrew S Thompson
Thomas R Verhoeven
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE178881T1 publication Critical patent/ATE178881T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT95906761T 1994-01-05 1995-01-03 Asymmetrische hydrierung von beta- oder gamma- ketoestern und von beta- oder gamma-ketoamiden ATE178881T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/177,481 US5508435A (en) 1992-07-29 1994-01-05 Asymmetric hydrogenation of beta- or gamma-ketoesters and beta- or gamma-ketoamides

Publications (1)

Publication Number Publication Date
ATE178881T1 true ATE178881T1 (de) 1999-04-15

Family

ID=22648777

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95906761T ATE178881T1 (de) 1994-01-05 1995-01-03 Asymmetrische hydrierung von beta- oder gamma- ketoestern und von beta- oder gamma-ketoamiden

Country Status (14)

Country Link
US (2) US5508435A (de)
EP (1) EP0738254B1 (de)
JP (1) JPH09508101A (de)
AT (1) ATE178881T1 (de)
AU (1) AU696140B2 (de)
CA (1) CA2178948A1 (de)
DE (1) DE69509065T2 (de)
DK (1) DK0738254T3 (de)
ES (1) ES2130586T3 (de)
GR (1) GR3029952T3 (de)
HR (1) HRP950002B1 (de)
TW (1) TW333524B (de)
WO (1) WO1995018784A1 (de)
YU (1) YU695A (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU712507B2 (en) * 1994-01-05 1999-11-11 Merck & Co., Inc. Chiral ruthenium (II) BINAP and t-BINAP compounds
JP3251828B2 (ja) * 1995-10-12 2002-01-28 高砂香料工業株式会社 光学活性シクロヘキサノール類の製造方法
JP3184758B2 (ja) * 1996-02-02 2001-07-09 高砂香料工業株式会社 光学活性４−ヒドロキシ−２−ピロリドンの製造方法
JPH1059992A (ja) * 1996-08-15 1998-03-03 Takasago Internatl Corp 新規ルテニウム錯体
JP3445074B2 (ja) * 1996-09-20 2003-09-08 高砂香料工業株式会社 ルテニウム−ホスフィン錯体の製造方法
DE19709069C2 (de) * 1997-03-06 2000-04-06 Asta Medica Ag Enantiomerenreine 3-Hydroxyoctandisäurediester, Verfahren zur Herstellung derselben durch asymmetrische katalytische Hydrierung sowie Verfahren zur Herstellung von R-(+)- und S-(-)-alpha-Liponsäure
JP2001158769A (ja) * 1999-12-02 2001-06-12 Univ Nagoya 触媒的不斉水素化法に基づく光学活性β−ヒドロキシスルホン酸化合物の合成方法
JP4601779B2 (ja) * 2000-07-25 2010-12-22 高砂香料工業株式会社 光学活性アルコールの製造方法
US6998495B2 (en) * 2001-10-24 2006-02-14 Kaneka Corporation Method for producing optically active 3,5-dihydroxycarboxylic acid derivative
GB0211716D0 (en) * 2002-05-22 2002-07-03 Phoenix Chemicals Ltd Process
WO2004089890A2 (en) * 2003-04-04 2004-10-21 Smithkline Beecham Corporation Process and intermediates for preparing benzazepines
GB2401864B (en) * 2003-05-21 2007-11-14 Phoenix Chemicals Ltd Process and catalytic composition
CN1894230A (zh) * 2003-12-15 2007-01-10 国际壳牌研究有限公司 液化木素纤维素材料的方法
CA2591796C (en) * 2004-12-23 2014-02-18 Shell Internationale Research Maatschappij B.V. A process for the hydrogenation of a lactone or of a carboxylic acid or an ester having a gamma-carbonyl group
US20070034345A1 (en) * 2005-06-15 2007-02-15 Leonardus Petrus Process for organosolv pulping and use of a gamma lactone in a solvent for organosolv pulping
EA201000214A1 (ru) 2007-08-28 2010-10-29 Рациофарм Гмбх Способ получения производных пентадикарбоновой кислоты
US8580978B2 (en) * 2009-08-07 2013-11-12 Shell Oil Company Process for preparing a hydroxyacid or hydroxyester
US20110112326A1 (en) * 2009-08-07 2011-05-12 Jean-Paul Lange Process for hydrogenation
US9249378B2 (en) 2013-08-02 2016-02-02 Eastman Chemical Company Aqueous cleaning compositions having enhanced properties
US9255059B2 (en) 2013-08-02 2016-02-09 Eastman Chemical Company Method for producing an alkyl 3-hydroxybutyrate
US9163202B2 (en) 2013-08-02 2015-10-20 Eastman Chemical Company Aqueous cleaning compositions including an alkyl 3-hydroxybutyrate
US9388114B2 (en) 2013-08-02 2016-07-12 Eastman Chemical Company Compositions including an alkyl 3-hydroxybutyrate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52105421A (en) * 1976-03-01 1977-09-03 Shin Meiwa Ind Co Ltd Apparatus for preventing drop of cargo box of dump car or the like
JPS53105421A (en) * 1977-02-28 1978-09-13 Sagami Chem Res Center Preparation of optical active alpha-hydroxycarboxylic acid esters acid esters
JPH0699367B2 (ja) * 1987-06-11 1994-12-07 高砂香料工業株式会社 光学活性アルコ−ルの製法
JPH0667947B2 (ja) * 1987-09-08 1994-08-31 高砂香料工業株式会社 ルテニウム−ホスフイン錯体
EP0484271B1 (de) * 1990-11-02 1994-10-19 Ciba-Geigy Ag Verfahren zur Herstellung von optisch aktiven aliphatischen Hydroxycarbonsäureestern

Also Published As

Publication number Publication date
DE69509065D1 (de) 1999-05-20
GR3029952T3 (en) 1999-07-30
YU695A (sh) 1997-09-30
DE69509065T2 (de) 1999-09-23
US5508435A (en) 1996-04-16
DK0738254T3 (da) 1999-10-25
WO1995018784A1 (en) 1995-07-13
HRP950002B1 (en) 1999-12-31
HRP950002A2 (en) 1997-06-30
AU696140B2 (en) 1998-09-03
JPH09508101A (ja) 1997-08-19
AU1522695A (en) 1995-08-01
EP0738254B1 (de) 1999-04-14
CA2178948A1 (en) 1995-07-13
US5596113A (en) 1997-01-21
EP0738254A1 (de) 1996-10-23
ES2130586T3 (es) 1999-07-01
TW333524B (en) 1998-06-11

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