ATE179607T1 - Verwendung von polyisoprenyl pyrophosphate analogen zur hemmung des proteinisoprenylations - Google Patents

Verwendung von polyisoprenyl pyrophosphate analogen zur hemmung des proteinisoprenylations

Info

Publication number
ATE179607T1
ATE179607T1 AT91202616T AT91202616T ATE179607T1 AT E179607 T1 ATE179607 T1 AT E179607T1 AT 91202616 T AT91202616 T AT 91202616T AT 91202616 T AT91202616 T AT 91202616T AT E179607 T1 ATE179607 T1 AT E179607T1
Authority
AT
Austria
Prior art keywords
independently represent
isoprenylation
pyrophosphate analogue
polyisoprenyl
polyisoprenyl pyrophosphate
Prior art date
Application number
AT91202616T
Other languages
English (en)
Inventor
Louis H Cohen
Boom Jacobus H Van
Der Marel Gijsbert A Van
Adrianus P R M Valentijn
Original Assignee
Tno
Univ Leiden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno, Univ Leiden filed Critical Tno
Application granted granted Critical
Publication of ATE179607T1 publication Critical patent/ATE179607T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT91202616T 1991-10-07 1991-10-07 Verwendung von polyisoprenyl pyrophosphate analogen zur hemmung des proteinisoprenylations ATE179607T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91202616A EP0540782B1 (de) 1991-10-07 1991-10-07 Verwendung von Polyisoprenyl pyrophosphate Analogen zur Hemmung des Proteinisoprenylations

Publications (1)

Publication Number Publication Date
ATE179607T1 true ATE179607T1 (de) 1999-05-15

Family

ID=8207934

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91202616T ATE179607T1 (de) 1991-10-07 1991-10-07 Verwendung von polyisoprenyl pyrophosphate analogen zur hemmung des proteinisoprenylations

Country Status (7)

Country Link
EP (1) EP0540782B1 (de)
JP (1) JP3518611B2 (de)
AT (1) ATE179607T1 (de)
DE (1) DE69131199T2 (de)
DK (1) DK0540782T3 (de)
ES (1) ES2133278T3 (de)
GR (1) GR3030795T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2267494B (en) * 1992-06-02 1995-09-20 Ciba Geigy Ag Trisamidodithionodiphosphates
US5883066A (en) * 1993-06-28 1999-03-16 The Procter & Gamble Company Liquid detergent compositions containing cellulase and amine
HUT77406A (hu) * 1994-03-15 1998-04-28 Eisai Co., Ltd., 1-(4-Amino-5-tio-pent-2-en)-il oldalláncot tartalmazó peptidomimetikumok és az ezeket tartalmazó gyógyszerkészítmények
US5574025A (en) * 1994-10-26 1996-11-12 Merck & Co., Inc. Inhibitors of prenyl-protein transferases
US6624147B1 (en) 1999-09-28 2003-09-23 Rijksuniversiteit Leiden Inhibitors of prenylated pyrophosphate consuming enzymes
EP1090909A1 (de) * 1999-09-28 2001-04-11 Rijksuniversiteit Leiden Hemmer für Enzyme, die Prenylpyrophosphate umsetzen
AU1226001A (en) * 1999-11-09 2001-06-06 Alcon Universal Limited Phospholipids of hydroxyeicosatetraenoic acid-like derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871721A (en) * 1988-01-11 1989-10-03 E. R. Squibb & Sons, Inc. Phosphorus-containing squalene synthetase inhibitors
JP2714402B2 (ja) * 1988-07-13 1998-02-16 日清製粉株式会社 癌転移抑制剤
EP0356866A3 (de) * 1988-08-29 1991-03-27 E.R. SQUIBB & SONS, INC. Phosphor enthaltende Squalen-Synthetase-Inhibitoren und Verfahren
US5025003A (en) * 1989-09-18 1991-06-18 E. R. Squibb & Sons, Inc. Isoprenoid phosphinylformic acid squalene synthetase inhibitors

Also Published As

Publication number Publication date
EP0540782B1 (de) 1999-05-06
DE69131199D1 (de) 1999-06-10
DK0540782T3 (da) 1999-11-01
JP3518611B2 (ja) 2004-04-12
ES2133278T3 (es) 1999-09-16
GR3030795T3 (en) 1999-11-30
DE69131199T2 (de) 1999-08-26
JPH07188028A (ja) 1995-07-25
EP0540782A1 (de) 1993-05-12

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ATE179607T1 (de) Verwendung von polyisoprenyl pyrophosphate analogen zur hemmung des proteinisoprenylations
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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee