ATE179801T1 - Verfahren zur trennung von high density lipoprotein aus blutproben - Google Patents
Verfahren zur trennung von high density lipoprotein aus blutprobenInfo
- Publication number
- ATE179801T1 ATE179801T1 AT93119355T AT93119355T ATE179801T1 AT E179801 T1 ATE179801 T1 AT E179801T1 AT 93119355 T AT93119355 T AT 93119355T AT 93119355 T AT93119355 T AT 93119355T AT E179801 T1 ATE179801 T1 AT E179801T1
- Authority
- AT
- Austria
- Prior art keywords
- hdl
- silica
- blood sample
- high density
- density lipoprotein
- Prior art date
Links
- 108010010234 HDL Lipoproteins Proteins 0.000 title abstract 6
- 102000015779 HDL Lipoproteins Human genes 0.000 title abstract 6
- 239000008280 blood Substances 0.000 title abstract 4
- 210000004369 blood Anatomy 0.000 title abstract 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 7
- 239000002250 absorbent Substances 0.000 abstract 3
- 230000002745 absorbent Effects 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 3
- 239000000377 silicon dioxide Substances 0.000 abstract 3
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 abstract 2
- 239000011148 porous material Substances 0.000 abstract 2
- 108010004103 Chylomicrons Proteins 0.000 abstract 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000005289 controlled pore glass Substances 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229920000447 polyanionic polymer Polymers 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/405—Concentrating samples by adsorption or absorption
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Ecology (AREA)
- Endocrinology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/990,592 US5290703A (en) | 1992-12-14 | 1992-12-14 | Method for the separation of high density lipoprotein from blood samples |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE179801T1 true ATE179801T1 (de) | 1999-05-15 |
Family
ID=25536307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93119355T ATE179801T1 (de) | 1992-12-14 | 1993-12-01 | Verfahren zur trennung von high density lipoprotein aus blutproben |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5290703A (de) |
| EP (1) | EP0602455B1 (de) |
| JP (1) | JPH06213901A (de) |
| AT (1) | ATE179801T1 (de) |
| AU (1) | AU667984B2 (de) |
| CA (1) | CA2111350C (de) |
| DE (1) | DE69324777T2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5401466A (en) * | 1993-06-01 | 1995-03-28 | Miles Inc. | Device for the direct measurement of low density lipoprotein cholesterol |
| US5409840A (en) * | 1993-10-12 | 1995-04-25 | Miles Inc. | Purification and recovery of lipoprotein cholesterol |
| WO1996010177A1 (en) * | 1994-09-28 | 1996-04-04 | Spectral Diagnostics Inc. | Method and device for determination of proteins |
| DE19505894A1 (de) * | 1995-02-21 | 1996-08-22 | Boehringer Mannheim Gmbh | Verfahren und Reagenz zur spezifischen Bestimmung von LDL in Serumproben |
| IL129456A0 (en) * | 1996-12-12 | 2000-02-29 | Siegel Gunter | Molecular model for arteriosclerosis |
| JP3441993B2 (ja) | 1999-01-27 | 2003-09-02 | 松下電器産業株式会社 | コレステロールセンサ |
| US7118921B1 (en) * | 1999-06-24 | 2006-10-10 | Mcmaster University | Incorporation and applications of biomolecular interactions within a carrier |
| CA2356364C (en) * | 1999-11-22 | 2003-12-09 | Matsushita Electric Industrial Co., Ltd. | Cholesterol sensor and method for determining cholesterol |
| JP3989223B2 (ja) * | 2001-11-05 | 2007-10-10 | 協和メデックス株式会社 | 循環器系疾患の診断方法 |
| WO2004022540A2 (en) * | 2002-09-06 | 2004-03-18 | Fujisawa Pharmaceutical Co., Ltd. | Pyridazinone and pyridone derivatives as adenosine antagonists |
| US20050054003A1 (en) * | 2003-09-10 | 2005-03-10 | Stenland Christopher J. | Prion clearance using particulate metal oxides |
| JP5355674B2 (ja) * | 2011-01-11 | 2013-11-27 | 富士フイルム株式会社 | 血液中の高密度リポタンパク質の除去方法 |
| WO2017100798A1 (en) | 2015-12-11 | 2017-06-15 | Siemens Healthcare Diagnostics Inc. | Specimen container and method for separating serum or plasma from whole blood |
| EP3538865A4 (de) | 2016-11-14 | 2019-12-25 | Siemens Healthcare Diagnostics Inc. | Vorrichtung zur probenvorbereitung |
| CN111718404A (zh) * | 2020-06-10 | 2020-09-29 | 光景生物科技(苏州)有限公司 | 一种分离血清中高密度脂蛋白的装置、其制备方法及分离血清中高密度脂蛋白的方法 |
| US12050052B1 (en) | 2021-08-06 | 2024-07-30 | Babson Diagnostics, Inc. | Refrigerated carrier device for biological samples |
| EP4505185A1 (de) | 2022-04-06 | 2025-02-12 | Babson Diagnostics, Inc. | Automatisierte zentrifugenbeschickungsvorrichtung |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55159158A (en) * | 1979-05-31 | 1980-12-11 | Wako Pure Chem Ind Ltd | Novel reagent for separation of lipoprotein |
| EP0180720B1 (de) * | 1981-09-10 | 1990-06-13 | B. Braun-SSC AG | Vorrichtung zur selektiven extrakorporalen Präzipation von Low Density Lipoprotenen aus Vollserum oder Plasma |
| FR2533704B1 (fr) * | 1982-09-27 | 1986-03-21 | Spiral | Dosage immunologique dans le serum de l'apolipoproteine b des lipoproteines de basse densite |
| CA1221307A (en) * | 1982-12-02 | 1987-05-05 | Nobutaka Tani | Adsorbent and process for preparing the same |
| DE3338836A1 (de) * | 1983-10-26 | 1985-05-09 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung der low density lipoproteine (ldl) und reagenz zu seiner durchfuehrung |
| JPS62186940A (ja) * | 1986-02-10 | 1987-08-15 | Kanegafuchi Chem Ind Co Ltd | リポ蛋白用吸着体 |
| IL79945A (en) * | 1986-09-04 | 1991-06-10 | I D L International Diagnostic | Method for the quantitative determination of total cholesterol in blood |
| IL89123A (en) * | 1989-01-31 | 1993-08-18 | Ilana Tamir | Method for determination of ldl-cholesterol |
| US5118613A (en) * | 1989-11-17 | 1992-06-02 | Abbott Laboratories | Determination of hdl whole blood |
| US5034332A (en) * | 1990-08-06 | 1991-07-23 | Wisconsin Alumni Research Foundation | Assay for high density lipoprotein cholesterol |
| US5286626A (en) * | 1991-12-13 | 1994-02-15 | Actimed Laboratories, Inc. | Process and apparatus for direct determination of low density lipoprotein |
| US5460974A (en) * | 1992-10-13 | 1995-10-24 | Miles Inc. | Method of assaying whole blood for HDL cholesterol |
-
1992
- 1992-12-14 US US07/990,592 patent/US5290703A/en not_active Expired - Fee Related
-
1993
- 1993-12-01 DE DE69324777T patent/DE69324777T2/de not_active Expired - Fee Related
- 1993-12-01 AT AT93119355T patent/ATE179801T1/de not_active IP Right Cessation
- 1993-12-01 EP EP93119355A patent/EP0602455B1/de not_active Expired - Lifetime
- 1993-12-13 CA CA002111350A patent/CA2111350C/en not_active Expired - Fee Related
- 1993-12-13 JP JP5311543A patent/JPH06213901A/ja active Pending
- 1993-12-13 AU AU52357/93A patent/AU667984B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06213901A (ja) | 1994-08-05 |
| EP0602455A2 (de) | 1994-06-22 |
| CA2111350C (en) | 2001-07-17 |
| DE69324777T2 (de) | 1999-12-02 |
| EP0602455B1 (de) | 1999-05-06 |
| AU667984B2 (en) | 1996-04-18 |
| AU5235793A (en) | 1994-06-23 |
| DE69324777D1 (de) | 1999-06-10 |
| US5290703A (en) | 1994-03-01 |
| EP0602455A3 (de) | 1995-08-16 |
| CA2111350A1 (en) | 1994-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |