ATE180669T1 - Verwendung von pregnanderivaten zur behandlung von tumoren - Google Patents

Verwendung von pregnanderivaten zur behandlung von tumoren

Info

Publication number
ATE180669T1
ATE180669T1 AT94200523T AT94200523T ATE180669T1 AT E180669 T1 ATE180669 T1 AT E180669T1 AT 94200523 T AT94200523 T AT 94200523T AT 94200523 T AT94200523 T AT 94200523T AT E180669 T1 ATE180669 T1 AT E180669T1
Authority
AT
Austria
Prior art keywords
derivatives
pregnander
treat tumors
alpha
tumors
Prior art date
Application number
AT94200523T
Other languages
English (en)
Inventor
Godefridus Hermanus Jo Deckers
Helenius Jan Kloosterboer
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE180669T1 publication Critical patent/ATE180669T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Fats And Perfumes (AREA)
AT94200523T 1993-03-05 1994-03-02 Verwendung von pregnanderivaten zur behandlung von tumoren ATE180669T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93200631 1993-03-05

Publications (1)

Publication Number Publication Date
ATE180669T1 true ATE180669T1 (de) 1999-06-15

Family

ID=8213673

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94200523T ATE180669T1 (de) 1993-03-05 1994-03-02 Verwendung von pregnanderivaten zur behandlung von tumoren

Country Status (14)

Country Link
US (1) US5512556A (de)
EP (1) EP0613687B1 (de)
JP (1) JP3391539B2 (de)
KR (1) KR100312061B1 (de)
AT (1) ATE180669T1 (de)
AU (1) AU671706B2 (de)
CA (1) CA2116829C (de)
DE (1) DE69418744T2 (de)
DK (1) DK0613687T3 (de)
ES (1) ES2134313T3 (de)
GR (1) GR3031114T3 (de)
NO (1) NO307447B1 (de)
NZ (1) NZ260017A (de)
ZA (1) ZA941464B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4334616B2 (ja) * 1994-09-22 2009-09-30 ナームローゼ・フエンノートチヤツプ・オルガノン 湿式粒状化による投与単位体を製造する方法
IL123984A (en) 1997-04-22 2004-09-27 Akzo Nobel Nv Pharmacological dosage units containing tibolone and carrier pharmacy are acceptable
EP1121375B1 (de) * 1998-10-16 2003-05-02 Akzo Nobel N.V. (7alpha,17alpha)-17-hydroxy-7-methyl-19-nor-17-pregn-5-(10)-en-20-yn-3-on als reine verbindung
ATE246703T1 (de) * 1999-04-06 2003-08-15 Akzo Nobel Nv Oral wirksame 7-alpha-alkyl androgene
US6677329B1 (en) 1999-09-06 2004-01-13 Akzo Nobel N V. Non-aromatic estrogenic steroids with a hydrocarbon substituent in position 11
AU8201601A (en) 2000-07-28 2002-02-13 Akzo Nobel Nv 16alpha-methyl or ethyl substituted estrogens
WO2003032924A2 (en) * 2001-10-18 2003-04-24 Ivax Corporation Novel tibolone formulations
GB0125061D0 (en) * 2001-10-18 2001-12-12 Norton Healthcare Ltd Pharmaceutical composition
JP2005518412A (ja) * 2002-01-22 2005-06-23 アクゾ・ノベル・エヌ・ベー 内因性エストロゲンの合成を阻害する薬物の投与に伴う愁訴の治療におけるチボロン
HRP20050430A2 (en) * 2002-11-20 2005-06-30 Akzo Nobel N.V. Pharmaceutical tablets containing tibolone and a coating
UA89964C2 (ru) 2004-09-08 2010-03-25 Н.В. Органон 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
US20060211667A1 (en) * 2005-03-21 2006-09-21 Eric Marchewitz Use of pregnane steroid derivatives for enhancing physical performance
CN116987680A (zh) * 2022-04-25 2023-11-03 复旦大学 支链氨基酸转氨酶1的功能获得性突变体及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3515719A (en) 1967-03-15 1970-06-02 Upjohn Co 7-methyl-6,19-epoxy steroids of the androstane series
US4701450A (en) * 1984-03-21 1987-10-20 Akzo N.V. Steroids for use as immunomodulators
IE63051B1 (en) * 1989-03-18 1995-03-22 Akzo Nv Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn- 3-one
FR2706454B1 (fr) * 1993-06-17 1995-09-15 Roussel Uclaf Nouveaux 19-Nor stéroïdes, procédé et intermédiaires de préparation, application comme médicaments et compositions pharmaceutiques les contenant.

Also Published As

Publication number Publication date
JPH072673A (ja) 1995-01-06
US5512556A (en) 1996-04-30
EP0613687B1 (de) 1999-06-02
EP0613687A1 (de) 1994-09-07
JP3391539B2 (ja) 2003-03-31
DK0613687T3 (da) 1999-12-06
GR3031114T3 (en) 1999-12-31
NO940777L (no) 1994-09-06
ZA941464B (en) 1994-09-27
DE69418744D1 (de) 1999-07-08
CA2116829A1 (en) 1994-09-06
KR100312061B1 (ko) 2001-12-28
DE69418744T2 (de) 1999-11-11
NO307447B1 (no) 2000-04-10
NZ260017A (en) 1997-06-24
CA2116829C (en) 2004-09-14
AU5754294A (en) 1994-09-08
NO940777D0 (no) 1994-03-04
ES2134313T3 (es) 1999-10-01
AU671706B2 (en) 1996-09-05
KR940021064A (ko) 1994-10-17

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee