ATE111521T1 - Polypeptid und dessen herstellung. - Google Patents

Polypeptid und dessen herstellung.

Info

Publication number
ATE111521T1
ATE111521T1 AT90104419T AT90104419T ATE111521T1 AT E111521 T1 ATE111521 T1 AT E111521T1 AT 90104419 T AT90104419 T AT 90104419T AT 90104419 T AT90104419 T AT 90104419T AT E111521 T1 ATE111521 T1 AT E111521T1
Authority
AT
Austria
Prior art keywords
polypeptide
useful
vector
transformant
dna
Prior art date
Application number
AT90104419T
Other languages
English (en)
Inventor
Kazuo Nakahama
Yoshihiko Kaisho
Koji Yoshimura
Reiko Sasada
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27463714&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE111521(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE111521T1 publication Critical patent/ATE111521T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/48Nerve growth factor [NGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT90104419T 1989-03-10 1990-03-08 Polypeptid und dessen herstellung. ATE111521T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP5898389 1989-03-10
JP12771089 1989-05-19
JP19365489 1989-07-26
JP26361389 1989-10-09

Publications (1)

Publication Number Publication Date
ATE111521T1 true ATE111521T1 (de) 1994-09-15

Family

ID=27463714

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90104419T ATE111521T1 (de) 1989-03-10 1990-03-08 Polypeptid und dessen herstellung.

Country Status (11)

Country Link
US (1) US6709837B1 (de)
EP (1) EP0386752B1 (de)
JP (1) JPH0780904B2 (de)
KR (1) KR0132425B1 (de)
AT (1) ATE111521T1 (de)
CA (1) CA2011833C (de)
DE (1) DE69012377T2 (de)
DK (1) DK0386752T3 (de)
ES (1) ES2059854T3 (de)
HK (1) HK34896A (de)
IE (1) IE65361B1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656435A (en) * 1989-08-28 1997-08-12 Takeda Chemical Industries, Ltd. Antibodies to peptides having NGF-like activity, said antibodies having no substantial cross-reactivity with NGF, and use thereof
US5180820A (en) * 1989-08-30 1993-01-19 Barde Yves Alain Brain-derived neurotrophic factor
GR1000980B (el) * 1989-08-30 1993-03-31 Max Planck Gesellschaft Νευροτροφινη-3,ενας νεος neυροτροφικος παραγοντας που σχετιζεται με τον παραγοντα αναπτυξης νευρων και τον νευροτροφικο παραγοντα που προερχεται απο τον εγκεφαλο.
US6933276B1 (en) 1989-08-30 2005-08-23 Regeneron Pharmaceuticals, Inc. Methods of treating peripheral neuropathies using neurotrophin-3
US5235043A (en) * 1990-04-06 1993-08-10 Synergen, Inc. Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins
US6511823B1 (en) * 1990-08-20 2003-01-28 American Cyanamid Corporation Heparin binding neurotrophic factor gene sequence
ATE154389T1 (de) * 1991-02-18 1997-06-15 Takeda Chemical Industries Ltd Verfahren zur herstellung von menschlichem ngf-2
US5389529A (en) * 1991-06-12 1995-02-14 Regeneron Pharmaceuticals, Inc. Modified lamβ signal sequence and processes for producing recombinant neurotrophins
EP0573904B1 (de) * 1992-06-08 2001-09-26 Takeda Chemical Industries, Ltd. Therapeutisches Agens für Neutropenie
WO1994012637A2 (en) * 1992-12-02 1994-06-09 Zymogenetics, Inc. Novel human amyloid protein precursor homologue and kunitz-type inhibitors
JP2732005B2 (ja) * 1992-12-14 1998-03-25 眞一 富永 ヒトst2をコードするdna、該dnaの発現産物、該dnaを発現させることによる発現産物の製造方法
JPH07246040A (ja) * 1993-07-06 1995-09-26 Takeda Chem Ind Ltd ニューロトロフィン−3遺伝子が不活性化された胚幹細胞および該遺伝子発現不全動物
US5877016A (en) * 1994-03-18 1999-03-02 Genentech, Inc. Human trk receptors and neurotrophic factor inhibitors
US5681931A (en) * 1995-03-15 1997-10-28 Becton, Dickinson And Company Human restrictin
US5864018A (en) * 1996-04-16 1999-01-26 Schering Aktiengesellschaft Antibodies to advanced glycosylation end-product receptor polypeptides and uses therefor
WO1998022575A2 (en) * 1996-11-22 1998-05-28 Human Genome Sciences, Inc. Nucleotide sequence of escherichia coli pathogenicity islands

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161152C (da) 1983-03-03 1991-11-11 Genentech Inc Polypeptid med egenskaber som human beta-nervevaekstfaktor og fremgangsmaade til fremstilling deraf, dna-isolat omfattende en sekvens som koder for polypeptidet, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farmaceutisk praeparat indeholdende polypeptidet og fremg. der omfatter anvendelsen af polypeptidet til fremst. af et farmaceutisk praeparat
US5180820A (en) * 1989-08-30 1993-01-19 Barde Yves Alain Brain-derived neurotrophic factor

Also Published As

Publication number Publication date
DE69012377T2 (de) 1995-05-04
KR900014428A (ko) 1990-10-23
JPH0780904B2 (ja) 1995-08-30
EP0386752B1 (de) 1994-09-14
KR0132425B1 (ko) 1998-04-14
CA2011833C (en) 2002-11-05
CA2011833A1 (en) 1990-09-10
DE69012377D1 (de) 1994-10-20
US6709837B1 (en) 2004-03-23
IE900785L (en) 1990-09-10
DK0386752T3 (da) 1994-12-05
ES2059854T3 (es) 1994-11-16
EP0386752A1 (de) 1990-09-12
IE65361B1 (en) 1995-10-18
JPH03204897A (ja) 1991-09-06
HK34896A (en) 1996-03-08

Similar Documents

Publication Publication Date Title
DE69012377D1 (de) Polypeptid und dessen Herstellung.
DE69229572D1 (de) Gliazellen-aktivierender Faktor und dessen Herstellung
AU704515C (en) Novel protein and process for producing the same
DE68922869D1 (de) Rezeptor-Proteine für humanen B-Zellen stimulierenden Faktor 2.
DE69019609D1 (de) Proteine und deren Herstellung.
DE3650788D1 (de) Produktion des pluripotenten Granulozyten-Koloniestimulierungsfaktors
ATE135712T1 (de) Polypeptid, dessen verfahren zur herstellung und dieses enthaltende pharmazeutische zusammensetzung und deren benutzung
DE69334350D1 (de) P- Selectin Ligandenprotein
MX26714A (es) Procedimiento para la preparacion de albumina de SUERO HUMANO VECTOR Y PLASMIDO USADOS ASI COMO LEVADURA METILOTROFICA TRANSFORMADA OBTENIDA
NZ211827A (en) Production of polypeptides having interferon activity, polypeptide compositions and dna
CA2066618A1 (en) Plasmids containing dna encoding the amino acid sequence of tcf-ii, transformed cells with the plasmids, and production method of biologically active substance using the transformed cells
ATE127844T1 (de) Dns und ihre verwendung.
ATE70302T1 (de) Verfahren zur expression von alpha-1-antitrypsin in bakterien und dessen verwendung in therapeutischen zusammensetzungen sowie vektoren und bakterien fuer ein solches verfahren und deren herstellung.
DE3856240D1 (de) Herstellung der p1 proteine und impfstoffe gegen gonorrhöe
ATE89317T1 (de) Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.
ES2088911T3 (es) Gen de la proteasa i de achromobacter y el producto de este gen.
DE69017793D1 (de) Produktion von menschlichen Nervenwachstumsfaktoren.
DE69115270D1 (de) Protein mit fibroblasten-wachstumsfaktor-rezeptoraktivität.
JPS6420083A (en) Preparation of human iga secretory cell

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time