ATE182883T1 - Therapeutische benzonitrile - Google Patents
Therapeutische benzonitrileInfo
- Publication number
- ATE182883T1 ATE182883T1 AT95909036T AT95909036T ATE182883T1 AT E182883 T1 ATE182883 T1 AT E182883T1 AT 95909036 T AT95909036 T AT 95909036T AT 95909036 T AT95909036 T AT 95909036T AT E182883 T1 ATE182883 T1 AT E182883T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- benzonitriles
- therapeutic
- hydrogen
- arylthiobenzonitrile
- Prior art date
Links
- 150000008359 benzonitriles Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical group [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/63—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9403449A GB9403449D0 (en) | 1994-02-23 | 1994-02-23 | Therapeutic benzonitriles |
| GB9416103A GB9416103D0 (en) | 1994-08-10 | 1994-08-10 | Therapeutic benzonitriles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE182883T1 true ATE182883T1 (de) | 1999-08-15 |
Family
ID=26304380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95909036T ATE182883T1 (de) | 1994-02-23 | 1995-02-23 | Therapeutische benzonitrile |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0748311B1 (de) |
| JP (1) | JPH10500104A (de) |
| AT (1) | ATE182883T1 (de) |
| AU (1) | AU1714095A (de) |
| DE (1) | DE69511247T2 (de) |
| ES (1) | ES2134441T3 (de) |
| IL (1) | IL112739A0 (de) |
| WO (1) | WO1995023133A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2151074C (en) * | 1994-07-05 | 2005-08-02 | Hirokazu Kagano | Method for producing 1,2-benzisothiazol-3-ones |
| US5691019A (en) * | 1995-05-01 | 1997-11-25 | General Electric Company | Foul release system |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4254144A (en) * | 1980-01-25 | 1981-03-03 | The Dow Chemical Company | Substituted benzonitriles having antiviral activity |
| IE75693B1 (en) * | 1990-07-10 | 1997-09-10 | Janssen Pharmaceutica Nv | HIV-inhibiting benzeneacetamide derivatives |
| AU8937491A (en) * | 1990-10-22 | 1992-05-20 | Research Corporation Technologies, Inc. | Aryl and heteroaryl compounds having anti-retrovirus activity |
| EP0507488A1 (de) * | 1991-03-27 | 1992-10-07 | Merck & Co. Inc. | Inhibitoren der HIV-1 reversen Transkriptase |
-
1995
- 1995-02-22 IL IL11273995A patent/IL112739A0/xx unknown
- 1995-02-23 WO PCT/GB1995/000375 patent/WO1995023133A1/en not_active Ceased
- 1995-02-23 DE DE69511247T patent/DE69511247T2/de not_active Expired - Fee Related
- 1995-02-23 ES ES95909036T patent/ES2134441T3/es not_active Expired - Lifetime
- 1995-02-23 AT AT95909036T patent/ATE182883T1/de active
- 1995-02-23 EP EP95909036A patent/EP0748311B1/de not_active Expired - Lifetime
- 1995-02-23 JP JP7522197A patent/JPH10500104A/ja active Pending
- 1995-02-23 AU AU17140/95A patent/AU1714095A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10500104A (ja) | 1998-01-06 |
| IL112739A0 (en) | 1995-05-26 |
| EP0748311B1 (de) | 1999-08-04 |
| EP0748311A1 (de) | 1996-12-18 |
| AU1714095A (en) | 1995-09-11 |
| DE69511247D1 (de) | 1999-09-09 |
| WO1995023133A1 (en) | 1995-08-31 |
| ES2134441T3 (es) | 1999-10-01 |
| DE69511247T2 (de) | 1999-12-09 |
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