ATE183189T1 - Antifungale sordaridinderivate - Google Patents

Antifungale sordaridinderivate

Info

Publication number
ATE183189T1
ATE183189T1 AT95938407T AT95938407T ATE183189T1 AT E183189 T1 ATE183189 T1 AT E183189T1 AT 95938407 T AT95938407 T AT 95938407T AT 95938407 T AT95938407 T AT 95938407T AT E183189 T1 ATE183189 T1 AT E183189T1
Authority
AT
Austria
Prior art keywords
derivatives
antifungal
sordaridine
chem
formula
Prior art date
Application number
AT95938407T
Other languages
English (en)
Inventor
Jose Julio Martin
Gonzalo Jesus Chicharro
Jose Ramon Ruiz Gomez
De Las Heras Federico Gomez
Michael Victor Hayes
Michael John Dawson
Howard Geoffrey Wildman
Richard Hall
Original Assignee
Glaxo Wellcome Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Sa filed Critical Glaxo Wellcome Sa
Application granted granted Critical
Publication of ATE183189T1 publication Critical patent/ATE183189T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT95938407T 1994-11-08 1995-11-06 Antifungale sordaridinderivate ATE183189T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94500174A EP0711783A1 (de) 1994-11-08 1994-11-08 Antifungale Sordarinderivate

Publications (1)

Publication Number Publication Date
ATE183189T1 true ATE183189T1 (de) 1999-08-15

Family

ID=8218171

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95938407T ATE183189T1 (de) 1994-11-08 1995-11-06 Antifungale sordaridinderivate

Country Status (11)

Country Link
US (1) US6054478A (de)
EP (2) EP0711783A1 (de)
JP (1) JPH11502188A (de)
AT (1) ATE183189T1 (de)
AU (1) AU3981095A (de)
DE (1) DE69511424T2 (de)
DK (1) DK0791007T3 (de)
ES (1) ES2136887T3 (de)
GR (1) GR3031781T3 (de)
SI (1) SI0791007T1 (de)
WO (1) WO1996014327A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998011891A1 (en) * 1996-09-18 1998-03-26 Merck & Co., Inc. Sordarin and derivatives thereof for use as crop antifungal agents
US6436395B1 (en) 1996-09-18 2002-08-20 Merck & Co., Inc. Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control
US6040463A (en) * 1996-10-07 2000-03-21 Merck & Co., Inc. Sordarin derivatives
US6096511A (en) * 1997-06-10 2000-08-01 Merck & Co., Inc. Protein elongation factor 2 as a target for antifungal and antiparasitic agents
DE69813833T2 (de) * 1997-08-22 2004-01-15 Merck & Co Inc 4-cyano-4-deformylsordarizin-derivate
US5972996A (en) * 1997-08-22 1999-10-26 Merck & Co., Inc. 4-cyano-4-deformylsordarin derivatives
US5965612A (en) * 1997-08-22 1999-10-12 Merck & Co., Inc. 4-cyano-4-deformylsordaricin derivatives
NZ502763A (en) * 1997-08-22 2002-03-28 Merck & Co Inc 4-cyano-4-deformylsordarin derivatives
US6136853A (en) * 1997-10-03 2000-10-24 Merck & Co., Inc. Sordarin derivatives
US6410528B1 (en) 1998-05-11 2002-06-25 Glaxo Wellcome S.A. Morpholino ethers
MA26628A1 (fr) * 1998-05-11 2004-12-20 Glaxo Wellcome Sa Morpholino ethers
ATE255572T1 (de) 1998-10-26 2003-12-15 Merck & Co Inc Mikrobielle transformationsprodukte
AUPQ120899A0 (en) * 1999-06-25 1999-07-22 Fujisawa Pharmaceutical Co., Ltd. Novel compound
JP2003513963A (ja) * 1999-11-11 2003-04-15 グラクソ、ウェルカム、ソシエダッド、アノニマ 炭素環式誘導体
EP1228049A1 (de) 1999-11-11 2002-08-07 Glaxo Wellcome S.A. Antifungale sordaricinderivate
AU2001289063A1 (en) * 2000-09-15 2002-03-26 Bristol-Myers Squibb Company Novel thio derivatives of sordarin as antifungal agents
WO2003007878A2 (en) 2001-07-18 2003-01-30 Merck & Co., Inc. Antifungal agents of sordarin derivatives
EP1458725B1 (de) * 2001-12-14 2007-02-21 Merck & Co., Inc. Neues, aus kulturfermentierungen isoliertes sordarinderivat und wirkungen als antipilzmittel
RU2005119172A (ru) * 2002-12-18 2006-01-20 Пфайзер Продактс Инк. (Us) Производные 4-анилинхиназолина для лечения патологического роста клеток
CN108085273B (zh) * 2017-12-11 2022-01-21 暨南大学 一株抗真菌链霉菌及其代谢物、代谢物制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0615555B2 (ja) * 1985-08-14 1994-03-02 三共株式会社 抗生物質ゾフイマリン
JP3189443B2 (ja) * 1992-11-20 2001-07-16 萬有製薬株式会社 抗真菌性物質ｂｅ−３１４０５

Also Published As

Publication number Publication date
AU3981095A (en) 1996-05-31
DK0791007T3 (da) 2000-03-20
WO1996014327A1 (en) 1996-05-17
ES2136887T3 (es) 1999-12-01
US6054478A (en) 2000-04-25
SI0791007T1 (en) 1999-12-31
EP0791007B1 (de) 1999-08-11
DE69511424T2 (de) 1999-12-16
JPH11502188A (ja) 1999-02-23
DE69511424D1 (de) 1999-09-16
GR3031781T3 (en) 2000-02-29
EP0791007A1 (de) 1997-08-27
EP0711783A1 (de) 1996-05-15

Similar Documents

Publication Publication Date Title
DK0791007T3 (da) Antifungale sordaridinderivater
ATE226201T1 (de) Substituierte pyridylpyrazole
DE69319976D1 (de) 7-Substituierte-9-substituierte Glycylamido-6-Demethyl-6-Deoxytetracycline
FI906045A0 (fi) Kvaevehaltiga spirocykliska foereningar.
IT1269176B (it) Eterobicicli ad attivita' fungicida
NO944406D0 (no) Nye 7 se inhibitorer
PT918776E (pt) Sintese total de acilfulvenos antitumorais
NO20002834L (no) S-oksyd og S,S-dioksyd-tetrahydrothiopyran- fenyloksazolidinoner
SE9100920D0 (sv) New active compounds
ES2179254T3 (es) 1-poliarilpirazoles plaguicidas.
ITMI931012A1 (it) Composti spiro-piranici dotati di caratteristiche fotocromatiche
ATE156486T1 (de) Fungizide 3,4-diaryl-(5h)-furan-2-onederivate
ES2106058T3 (es) Derivados de benzamida.
DK0625520T3 (da) Thiazolotriazol- og thiazolodiazolderivater med fungicid aktivitet
FI901277A0 (fi) 2,5,6,7-tetranor-4,8-inter-m-fenylen pg1z-derivativ.
FI910366A0 (fi) Menetelmä deoksimulundokandiinin valmistamiseksi
ES2072936T3 (es) Derivados de pradimicin-amida.
DE69533573D1 (de) Anxiolytischer wirkstoff
ATE158794T1 (de) Thiazolylpyrrols als fungizide
ATE159253T1 (de) 2-thiazolylpyrroleakrylate mit fungizider wirkung

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee