ATE183389T1 - Triphenylethylene zur vorbeugung und behandlung von osteoporose - Google Patents

Triphenylethylene zur vorbeugung und behandlung von osteoporose

Info

Publication number
ATE183389T1
ATE183389T1 AT95929903T AT95929903T ATE183389T1 AT E183389 T1 ATE183389 T1 AT E183389T1 AT 95929903 T AT95929903 T AT 95929903T AT 95929903 T AT95929903 T AT 95929903T AT E183389 T1 ATE183389 T1 AT E183389T1
Authority
AT
Austria
Prior art keywords
pct
triphenylethylene
preventing
treating osteoporosis
sec
Prior art date
Application number
AT95929903T
Other languages
English (en)
Inventor
Michael Degregorio
Lauri Veikko Matti Kangas
Pirkko Haerkoenen
Kalervo Vaeaenaenen
Aire Laine
Valerie Wiebe
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Application granted granted Critical
Publication of ATE183389T1 publication Critical patent/ATE183389T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Materials For Photolithography (AREA)
AT95929903T 1994-09-07 1995-09-06 Triphenylethylene zur vorbeugung und behandlung von osteoporose ATE183389T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9418067A GB9418067D0 (en) 1994-09-07 1994-09-07 Triphenylethylenes for the prevention and treatment of osteoporosis

Publications (1)

Publication Number Publication Date
ATE183389T1 true ATE183389T1 (de) 1999-09-15

Family

ID=10761007

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95929903T ATE183389T1 (de) 1994-09-07 1995-09-06 Triphenylethylene zur vorbeugung und behandlung von osteoporose

Country Status (17)

Country Link
US (2) US5750576A (de)
EP (1) EP0779808B1 (de)
JP (1) JP3910211B2 (de)
AT (1) ATE183389T1 (de)
CA (1) CA2198389C (de)
DE (1) DE69511566T2 (de)
DK (1) DK0779808T3 (de)
ES (1) ES2135083T3 (de)
FI (1) FI118755B (de)
GB (1) GB9418067D0 (de)
GR (1) GR3031109T3 (de)
IL (1) IL115171A (de)
NO (1) NO315785B1 (de)
NZ (1) NZ291836A (de)
SI (1) SI0779808T1 (de)
WO (1) WO1996007402A1 (de)
ZA (1) ZA957481B (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504074A (en) * 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
GB9609171D0 (en) * 1996-05-02 1996-07-03 Orion Yhtymae Oy Antioxidant compounds
US6117911A (en) 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
GB9803521D0 (en) * 1998-02-19 1998-04-15 Orion Yhtymo Oy New compounds and pharmaceutical compositions thereof
US20040176470A1 (en) * 1998-05-07 2004-09-09 Steiner Mitchell S. Method for treatment and chemoprevention of prostate cancer
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
EP1705169A3 (de) * 1999-11-16 2006-11-15 Hormos Medical Ltd. Triphenylalkenderivate und ihre Anwendung als selektive Modulatoren des Östrogenrezeptors
TW593256B (en) * 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
US6245819B1 (en) * 2000-07-21 2001-06-12 Hormos Medical Oy, Ltd. Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US20080249183A1 (en) * 2001-11-29 2008-10-09 Steiner Mitchell S Treatment of androgen-deprivation induced osteoporosis
US20050080143A1 (en) * 2001-11-29 2005-04-14 Steiner Mitchell S. Treatment of androgen-deprivation induced osteoporosis
US20040214898A1 (en) * 2001-11-29 2004-10-28 Steiner Mitchell S. Methods for treating hot flashes
US20060269611A1 (en) * 2001-11-29 2006-11-30 Steiner Mitchell S Prevention and treatment of androgen-deprivation induced osteoporosis
US20040248989A1 (en) * 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
US8236861B2 (en) 2004-02-13 2012-08-07 Hormos Medical Corporation Method for enhancing the bioavailablity of ospemifene
US8642079B2 (en) * 2004-02-23 2014-02-04 Hormos Medical Corporation Solid formulations of ospemifene
US20050187302A1 (en) * 2004-02-23 2005-08-25 Hormos Medical Corporation Method for treatment or prevention of osteoporosis in individuals with high bone turnover
MXPA06012758A (es) 2004-05-04 2007-01-16 Hormos Medical Ltd Novedosas formulaciones orales de ospemifeno.
US20060293294A1 (en) * 2004-09-03 2006-12-28 Hormos Medical Corporation Method for treatment or prevention of androgen deficiency
US20060270641A1 (en) * 2005-05-31 2006-11-30 Steiner Mitchell S Method for chemoprevention of prostate cancer
US8637706B2 (en) 2005-11-28 2014-01-28 Gtx, Inc. Nuclear receptor binding agents
US8546451B2 (en) 2005-11-28 2013-10-01 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
US9409856B2 (en) 2005-11-28 2016-08-09 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
US8158828B2 (en) 2005-11-28 2012-04-17 Gtx, Inc. Nuclear receptor binding agents
MX2008014825A (es) 2006-05-22 2008-12-01 Hormos Medical Ltd Moduladores selectivos del receptor de estrogeno o inhibidores de aromatasa para tratar prostatitis cronica no bacteriana.
US20080176255A1 (en) * 2007-01-23 2008-07-24 Edward Sobek Mold detection composition and methods
PL2121553T3 (pl) 2007-02-14 2012-11-30 Hormos Medical Ltd Sposób wytwarzania cennych terapeutycznie pochodnych trifenylobutenu
WO2008099060A2 (en) 2007-02-14 2008-08-21 Hormos Medical Ltd Methods for the preparation of fispemifene from ospemifene
WO2008157335A2 (en) * 2007-06-13 2008-12-24 Quatrx Pharmaceuticals Company Methods for the treatment of erectile dysfunction using fispemifene
US9427418B2 (en) 2009-02-23 2016-08-30 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
US9624161B2 (en) 2009-02-23 2017-04-18 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
KR101149529B1 (ko) 2009-09-11 2012-05-25 한국화학연구원 인덴온 유도체 및 이를 포함하는 약학적 조성물
EP2526080B1 (de) * 2010-01-19 2014-03-26 Cambrex Karlskoga AB Neue verfahren zur herstellung von benzophenonderivaten
US9321712B2 (en) 2012-10-19 2016-04-26 Fermion Oy Process for the preparation of ospemifene
WO2014060640A1 (en) 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene
CN103739456A (zh) * 2013-12-03 2014-04-23 镇江圣安医药有限公司 2-（对-（（z-4-氯-1,2-二苯基-1-丁烯基）苯氧基）乙醇的新型衍生物及其应用
US9975832B2 (en) 2014-12-29 2018-05-22 Olon S.P.A. Process for the preparation of ospemifene and fispemifene
US10138190B2 (en) 2015-01-09 2018-11-27 Glenmark Pharmaceuticals Limited Process for preparation of ospemifene
MX2017011469A (es) 2015-03-10 2018-01-23 Shionogi Inc Dispersiones sólidas.
KR102052133B1 (ko) * 2017-08-10 2019-12-05 고려대학교 산학협력단 당 부가된 오스페미펜, 이의 제조방법 및 이를 유효성분으로 함유하는 약학적 조성물
GR1009542B (el) 2018-04-25 2019-06-07 Φαρματεν Α.Β.Ε.Ε. Καψουλα μαλακης γελης που περιλαμβανει εναν εκλεκτικο ρυθμιστη οιστρογονικων υποδοχεων
KR20220115062A (ko) 2021-02-09 2022-08-17 (주)오스티오뉴로젠 크로몬 구조의 화합물을 포함하는 골다공증의 예방 및 치료용 약학적 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9207437D0 (en) * 1992-04-03 1992-05-20 Orion Yhtymae Oy Topical administration of toremifene and its metabolites

Also Published As

Publication number Publication date
DE69511566D1 (de) 1999-09-23
WO1996007402A1 (en) 1996-03-14
JP3910211B2 (ja) 2007-04-25
CA2198389A1 (en) 1996-03-14
IL115171A0 (en) 1995-12-31
NO315785B1 (no) 2003-10-27
FI970920A0 (fi) 1997-03-04
NZ291836A (en) 1998-06-26
FI970920L (fi) 1997-03-04
JPH10505079A (ja) 1998-05-19
IL115171A (en) 2001-08-26
AU3347895A (en) 1996-03-27
GR3031109T3 (en) 1999-12-31
EP0779808A1 (de) 1997-06-25
EP0779808B1 (de) 1999-08-18
SI0779808T1 (en) 1999-10-31
NO971037D0 (no) 1997-03-06
CA2198389C (en) 2007-02-20
GB9418067D0 (en) 1994-10-26
ZA957481B (en) 1996-04-09
FI118755B (fi) 2008-03-14
ES2135083T3 (es) 1999-10-16
US5750576A (en) 1998-05-12
NO971037L (no) 1997-04-29
DK0779808T3 (da) 2000-03-13
AU699845B2 (en) 1998-12-17
DE69511566T2 (de) 2000-04-27
US5912273A (en) 1999-06-15

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