ATE184008T1 - Pyrrolopyridinderivate als dopaminrezeptor liganden - Google Patents

Pyrrolopyridinderivate als dopaminrezeptor liganden

Info

Publication number
ATE184008T1
ATE184008T1 AT94906978T AT94906978T ATE184008T1 AT E184008 T1 ATE184008 T1 AT E184008T1 AT 94906978 T AT94906978 T AT 94906978T AT 94906978 T AT94906978 T AT 94906978T AT E184008 T1 ATE184008 T1 AT E184008T1
Authority
AT
Austria
Prior art keywords
pct
dopamine receptor
image
receptor ligands
pyrrolopyridine derivatives
Prior art date
Application number
AT94906978T
Other languages
English (en)
Inventor
Raymond Baker
Neil Roy Curtis
Janusz Jozef Kulagowski
Paul David Leeson
Adrian Leonard Smith
Mark Peter Ridgill
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939304110A external-priority patent/GB9304110D0/en
Priority claimed from GB939316260A external-priority patent/GB9316260D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE184008T1 publication Critical patent/ATE184008T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT94906978T 1993-03-01 1994-02-25 Pyrrolopyridinderivate als dopaminrezeptor liganden ATE184008T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939304110A GB9304110D0 (en) 1993-03-01 1993-03-01 Therapeutic agents
GB939316260A GB9316260D0 (en) 1993-08-05 1993-08-05 Therapeutic agents

Publications (1)

Publication Number Publication Date
ATE184008T1 true ATE184008T1 (de) 1999-09-15

Family

ID=26302518

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94906978T ATE184008T1 (de) 1993-03-01 1994-02-25 Pyrrolopyridinderivate als dopaminrezeptor liganden

Country Status (4)

Country Link
US (1) US5700809A (de)
AT (1) ATE184008T1 (de)
DE (1) DE69420394T2 (de)
ES (1) ES2134929T3 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9605065D0 (en) * 1996-03-11 1996-05-08 Merck Sharp & Dohme Therapeutic agents
US20070066641A1 (en) * 2003-12-19 2007-03-22 Prabha Ibrahim Compounds and methods for development of RET modulators
CN1925855B (zh) * 2003-12-19 2010-06-16 普莱希科公司 开发Ret调节剂的化合物和方法
JP2008503473A (ja) * 2004-06-17 2008-02-07 プレキシコン，インコーポレーテッド Ｃ−ｋｉｔ活性を調節する化合物
US7498342B2 (en) * 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
DE102004060659A1 (de) * 2004-12-15 2006-07-06 Lanxess Deutschland Gmbh Neue substituierte 1H-Pyrrolo[2,3-b]pyridine und deren Herstellung
US7846941B2 (en) * 2005-05-17 2010-12-07 Plexxikon, Inc. Compounds modulating c-kit and c-fms activity and uses therefor
US7935821B2 (en) * 2005-06-09 2011-05-03 Mallinckrodt Inc. Method for separation and purification of naltrexone by preparative chromatography
UA95244C2 (ru) 2005-06-22 2011-07-25 Плексикон, Инк. Соединения и способ модулирования активности киназ, и показания для их применения
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
PE20121126A1 (es) * 2006-12-21 2012-08-24 Plexxikon Inc Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
WO2008079909A1 (en) 2006-12-21 2008-07-03 Plexxikon, Inc. Pyrrolo [2,3-b] pyridines as kinase modulators
JP2010514695A (ja) 2006-12-21 2010-05-06 プレキシコン，インコーポレーテッド キナーゼ調節のための化合物および方法およびそのための適応症
WO2009012283A1 (en) 2007-07-17 2009-01-22 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
MY172424A (en) 2009-04-03 2019-11-25 Hoffmann La Roche Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
CN106220623A (zh) 2009-11-06 2016-12-14 普莱希科公司 用于激酶调节的化合物和方法及其适应症
US9624213B2 (en) 2011-02-07 2017-04-18 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
AR085279A1 (es) 2011-02-21 2013-09-18 Plexxikon Inc Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
ES3029867T3 (en) 2019-12-18 2025-06-25 Chdi Foundation Inc Compounds and probes for imaging huntingtin protein

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2044254B (en) * 1979-01-26 1983-01-26 Wyeth John & Brother Ltd Piperidine derivatives
US5124335A (en) * 1991-01-30 1992-06-23 Merck & Co., Inc. Substituted pyrollo-fused 6 membered heterocycles as angiotensin ii antagonists
BR9406128A (pt) * 1993-03-01 1996-02-27 Merck Sharp & Dohme Uso de um composto processo para o tratamento e/ou prevençao de distúrbios psicóticos composto composiçao farmacêutica processos para a preparaçao de um composto e de uma composiçao farmacêutica
US5576319A (en) * 1993-03-01 1996-11-19 Merck, Sharp & Dohme Ltd. Pyrrolo-pyridine derivatives
US5622950A (en) * 1993-03-01 1997-04-22 Merck, Sharp & Dohme Ltd. Pyrrolo-pyridine derivatives
GB9416162D0 (en) * 1994-08-10 1994-09-28 Merck Sharp & Dohme Therapeutic agents
GB9416189D0 (en) * 1994-08-10 1994-09-28 Merck Sharp & Dohme Therapeutic agents
DE69515177T2 (de) * 1994-08-10 2000-10-05 Merck Sharp & Dohme Ltd., Hoddesdon Tetrahydropyridinylmethylderivate von pyrrolo[2,3-b]pyridine

Also Published As

Publication number Publication date
DE69420394D1 (de) 1999-10-07
ES2134929T3 (es) 1999-10-16
DE69420394T2 (de) 2000-04-13
US5700809A (en) 1997-12-23

Similar Documents

Publication Publication Date Title
ATE184008T1 (de) Pyrrolopyridinderivate als dopaminrezeptor liganden
MX9401408A (es) Nuevos derivados heterociclicos.
ES2121193T3 (es) Derivados de bencimidazoles.
BR9606547A (pt) Novos derivados de pirimidona com atividade fungicida
PL310171A1 (en) Novel imidazopyridines
WO1994020459A3 (en) Pyrrolo-pyridine derivatives as dopamine receptor ligands
GB9305641D0 (en) Therapeutic agents
ES2145289T3 (es) Derivados tetrahidropiridinilmetilo de pirrolo(2,3-b)piridina.
DE69322250D1 (de) 3-hydroxypyridin-4-on-derivate als chelatbildner
ATE160773T1 (de) Kondensierte tricyclische heteroaromatische verbindungen als dopamin-rezeptor-subtyp-liganden
ATE330958T1 (de) Pyrazino 1'2':1,6öpyrido 3,4-böindolderivate
DE69431471D1 (de) Amide derivate als 5-ht1a liganden
ES2104509A1 (es) Nuevos compuestos derivados de 2-(3,4-disustituido-1-piperazinil)-5-fluoropirimidina.
ATE168855T1 (de) Halogenierte 4'-methoxyacetophenone als mikrobizide und konservierungsmittel
ATE155791T1 (de) Etoposid-derivate, ihre herstellung, ihre verwendung als medikament und ihre verwendung zur herstellung eines antikrebsmittels
TW282458B (de)
DK0691846T3 (da) Imidazoquinoxalinoner til behandling af sygdomme i centralnervesystemet
ES2101644A1 (es) Nuevo compuesto derivado del cromeno
ES2088320T3 (es) Derivados de carboestirilo.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties