ATE184010T1 - Makrozyklische verbindungen und ihre verwendung als pharmazeutika - Google Patents

Makrozyklische verbindungen und ihre verwendung als pharmazeutika

Info

Publication number: ATE184010T1
Authority: AT; Austria
Prior art keywords: group; optionally substituted; pharmaceuticals; macrocyclic compounds; alkoxy
Prior art date: 1993-12-03

Application number

AT94308803T

Other languages

English (en)

Inventor

Barry Peter Clark

John Richard Harris

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-03

Filing date

1994-11-29

Publication date

1999-09-15

1994-11-29 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1999-09-15 Application granted granted Critical

1999-09-15 Publication of ATE184010T1 publication Critical patent/ATE184010T1/de

Links

239000003814 drug Substances 0.000 title 1
150000002678 macrocyclic compounds Chemical class 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000004953 trihalomethyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT94308803T 1993-12-03 1994-11-29 Makrozyklische verbindungen und ihre verwendung als pharmazeutika ATE184010T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB939324871A GB9324871D0 (en)	1993-12-03	1993-12-03	Novel compounds

Publications (1)

Publication Number	Publication Date
ATE184010T1 true ATE184010T1 (de)	1999-09-15

Family

ID=10746120

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94308803T ATE184010T1 (de)	1993-12-03	1994-11-29	Makrozyklische verbindungen und ihre verwendung als pharmazeutika

Country Status (10)

Country	Link
US (2)	US5580900A (de)
EP (1)	EP0656362B1 (de)
JP (1)	JPH07196664A (de)
AT (1)	ATE184010T1 (de)
CA (1)	CA2137029A1 (de)
DE (1)	DE69420362T2 (de)
DK (1)	DK0656362T3 (de)
ES (1)	ES2134909T3 (de)
GB (1)	GB9324871D0 (de)
GR (1)	GR3031960T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997004797A1 (en) *	1995-07-26	1997-02-13	Warner-Lambert Company	Use of neuronal calcium channel blockers for the manufacture of a medicament for the treatment of psychoses, schizophrenia and cocaine or amphetamine addiction
WO1997009976A2 (en) *	1995-09-01	1997-03-20	Washington University	Method of reducing neurotoxic injury with zinc chelators
CN106749328A (zh) *	2016-11-21	2017-05-31	新乡学院	一种穴醚及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3847949A (en) *	1970-05-12	1974-11-12	Du Pont	Macrocyclic hetero imine complexing agents
FR2155926B1 (de) *	1971-10-15	1973-11-30	Cetrane Laboratoire
US4031111A (en) *	1973-01-08	1977-06-21	E. I. Du Pont De Nemours And Company	Macrocyclic hetero imine complexing agents
GB8528804D0 (en) *	1985-11-22	1985-12-24	Amersham Int Plc	Compounds
US5114688A (en) *	1990-01-23	1992-05-19	L'air Liquide, Societe Anonyme Pour L'etude Et Exploitation Des Procedes Georges Claude	Binuclear metal macrocyclic and macrobicyclic complexes for oxygen separation and transport
US5187103A (en) *	1991-01-31	1993-02-16	Miles Inc.	Colorimetric method and reagent for the assay of lithium in a test sample

1993
- 1993-12-03 GB GB939324871A patent/GB9324871D0/en active Pending
1994
- 1994-11-29 DK DK94308803T patent/DK0656362T3/da active
- 1994-11-29 ES ES94308803T patent/ES2134909T3/es not_active Expired - Lifetime
- 1994-11-29 AT AT94308803T patent/ATE184010T1/de not_active IP Right Cessation
- 1994-11-29 EP EP94308803A patent/EP0656362B1/de not_active Expired - Lifetime
- 1994-11-29 DE DE69420362T patent/DE69420362T2/de not_active Expired - Fee Related
- 1994-11-30 US US08/347,546 patent/US5580900A/en not_active Expired - Fee Related
- 1994-11-30 CA CA002137029A patent/CA2137029A1/en not_active Abandoned
- 1994-12-02 JP JP6298730A patent/JPH07196664A/ja active Pending
1996
- 1996-02-20 US US08/603,829 patent/US5574158A/en not_active Expired - Fee Related
1999
- 1999-11-25 GR GR990403053T patent/GR3031960T3/el unknown

Also Published As

Publication number	Publication date
JPH07196664A (ja)	1995-08-01
DK0656362T3 (da)	1999-12-13
DE69420362D1 (de)	1999-10-07
ES2134909T3 (es)	1999-10-16
US5580900A (en)	1996-12-03
EP0656362A1 (de)	1995-06-07
CA2137029A1 (en)	1995-06-04
US5574158A (en)	1996-11-12
GR3031960T3 (en)	2000-03-31
EP0656362B1 (de)	1999-09-01
DE69420362T2 (de)	2000-01-13
GB9324871D0 (en)	1994-01-19

Legal Events

Date	Code	Title	Description
2000-03-15	UEP	Publication of translation of european patent specification
2003-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69319380D1 (de)	1998-08-06	Azolverbindungen, deren Herstellung und Verwendung
FI905215A0 (fi)	1990-10-23	Bensimidazolderivat, deras framstaellning och anvaendning.
NO953305D0 (no)	1995-08-23	Antranilsyrederivat
DE69520545D1 (de)	2001-05-10	Chinolincarbonsäure-derivate
ID23891A (id)	2000-05-25	Senyawa heterosiklik tersubstitusi tergabung
GB9324872D0 (en)	1994-01-19	Pharmaceutical compounds
DE69432542D1 (de)	2003-05-28	Tetraderivate, ihre Herstellung und Verwendung
EP1306369A4 (de)	2007-02-14	Neue schwefelverbindungen und intermolekulare verbindungen, die diese als komponente enthalten
ATE184010T1 (de)	1999-09-15	Makrozyklische verbindungen und ihre verwendung als pharmazeutika
NO885313L (no)	1989-05-31	Nye forbindelser.
DK37580A (da)	1980-01-29	4,5-dihydro-4-oxofuran-2-carboxylsyrederivater samt deres fremstilling og anvendelse
ES2120498T3 (es)	1998-11-01	Nuevo compuesto tetraciclico.
DE3579682D1 (de)	1990-10-18	Tetrazolylderivate und ihre pharmazeutische verwendung.
NO912963D0 (no)	1991-07-30	Farmasoeytiske forbindelser.
ATE110375T1 (de)	1994-09-15	1-phenylalkyl-3-phenylharnstoff-derivate.
ES2142817T3 (es)	2000-05-01	Compuestos triciclicos como antagonistas de la angiotensina ii.
PT78498B (en)	1986-06-02	Chemical compounds
ES2183804T3 (es)	2003-04-01	Nuevo proceso para la produccion de cefalosporinas y nuevos intermedios en este proceso.
ES2158896T3 (es)	2001-09-16	Nuevo compuesto intermedio para uso en sintesis y procedimiento para producir un derivado de aminopiperazina.
ATE35982T1 (de)	1988-08-15	Azetidinderivate.
DE60132920D1 (de)	2008-04-03	Biphenylderivate
DE68912865D1 (de)	1994-03-17	Organische Verbindungen und ihre Verwendung als Pharmazeutika.