ATE184289T1 - Ribosomen-inaktivierende proteine, inaktive vorläuferformen derselben, verfahren zur herstellung und eine methode zur nutzung - Google Patents

Ribosomen-inaktivierende proteine, inaktive vorläuferformen derselben, verfahren zur herstellung und eine methode zur nutzung

Info

Publication number
ATE184289T1
ATE184289T1 AT91201436T AT91201436T ATE184289T1 AT E184289 T1 ATE184289 T1 AT E184289T1 AT 91201436 T AT91201436 T AT 91201436T AT 91201436 T AT91201436 T AT 91201436T AT E184289 T1 ATE184289 T1 AT E184289T1
Authority
AT
Austria
Prior art keywords
proteins
ribosome
inactivative
production
precursor forms
Prior art date
Application number
AT91201436T
Other languages
English (en)
Inventor
Terence A Walsh
Timothy D Hey
Alice E R Morgan
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Application granted granted Critical
Publication of ATE184289T1 publication Critical patent/ATE184289T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT91201436T 1990-06-11 1991-06-10 Ribosomen-inaktivierende proteine, inaktive vorläuferformen derselben, verfahren zur herstellung und eine methode zur nutzung ATE184289T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/535,636 US5248606A (en) 1990-06-11 1990-06-11 Dna encoding inactive precursor and active forms of maize ribosome inactivating protein

Publications (1)

Publication Number Publication Date
ATE184289T1 true ATE184289T1 (de) 1999-09-15

Family

ID=24135102

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91201436T ATE184289T1 (de) 1990-06-11 1991-06-10 Ribosomen-inaktivierende proteine, inaktive vorläuferformen derselben, verfahren zur herstellung und eine methode zur nutzung

Country Status (10)

Country Link
US (1) US5248606A (de)
EP (1) EP0466222B1 (de)
JP (1) JPH04279599A (de)
CN (1) CN1062172A (de)
AT (1) ATE184289T1 (de)
AU (1) AU638133B2 (de)
BR (1) BR9102418A (de)
CA (1) CA2044201A1 (de)
DE (1) DE69131589T2 (de)
HU (1) HUT58800A (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672683A (en) * 1989-09-07 1997-09-30 Alkermes, Inc. Transferrin neuropharmaceutical agent fusion protein
US5635384A (en) * 1990-06-11 1997-06-03 Dowelanco Ribosome-inactivating proteins, inactive precursor forms thereof, a process for making and a method of using
DE4040954C2 (de) * 1990-12-20 2001-05-17 Max Planck Gesellschaft Verfahren zur Erzeugung von pathogen-resistenten Pflanzen
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
DE69333270T2 (de) 1992-03-11 2004-08-05 Narhex Ltd. Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
JPH07504654A (ja) * 1992-03-11 1995-05-25 ナルヘックス　リミテッド オキソ及びヒドロキシ置換炭化水素のアミン誘導体
GB9304905D0 (en) * 1992-03-16 1993-04-28 Zeneca Ltd Processes
US5916772A (en) * 1992-06-16 1999-06-29 Whittier Institute For Diabetes And Endocrinology Recombinant production of saporin-containing proteins
US5332808A (en) * 1992-09-08 1994-07-26 North Carolina State University DNA encoding a ribosome inactivating protein
KR970001565B1 (ko) * 1993-08-28 1997-02-11 장기하 섬자리공 항바이러스성 단백질(pip) 유전자 및 이를 발현하는 미생물
EG23907A (en) * 1994-08-01 2007-12-30 Delta & Pine Land Co Control of plant gene expression
JPH0856655A (ja) * 1994-08-16 1996-03-05 Frontier:Kk 細胞致死剤および細胞死抑制剤
DE69734656T2 (de) * 1996-04-30 2006-08-10 Twinstrand Therapeutics Inc., Burnaby Antivirale variante von ricin-proteinen
EP0977862B8 (de) 1997-04-30 2009-09-16 Twinstrand Therapeutics Inc. Ricin-ähnliche toxine zur therapie von kreb, viraler oder parasitärer infektionen
US7247715B2 (en) 1997-04-30 2007-07-24 Twinstrand Therapeutics Inc. Ricin-like toxin variants for treatment of cancer, viral or parasitic infections
WO1999003492A1 (en) * 1997-07-16 1999-01-28 Sophie Chen Antiviral and antitumor agents
WO2000039291A1 (en) * 1998-12-31 2000-07-06 Rutgers, The State University Virus-resistant transgenic plants expressing l3
US6531125B1 (en) 1999-03-02 2003-03-11 Twinstrand Therapeutics Inc. Antiviral ricin-like proteins
CA2386237A1 (en) 1999-10-04 2001-04-12 Twinstrand Therapeutics Inc. Improved ricin-like toxins for treatment of cancer
GB0025217D0 (en) * 2000-10-14 2000-11-29 Cambridge Advanced Tech Plant cell death system
AU2006201828B2 (en) * 2000-10-14 2009-07-16 British American Tobacco (Investments) Limited Plant cell death system
GB0025225D0 (en) * 2000-10-14 2000-11-29 Cambridge Advanced Tech Plant cell death system
US7629309B2 (en) 2002-05-29 2009-12-08 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US20050191626A1 (en) * 2001-05-11 2005-09-01 Kazunari Taira Method for forming a stable complex comprising a transcription product and translation product of a dna encoding a desired polypeptide, a nucleic acid construct used for the method, a complex formed by the method, and screening of a functional protein and mrna or dna encoding the protein using the method
US20030072761A1 (en) 2001-10-16 2003-04-17 Lebowitz Jonathan Methods and compositions for targeting proteins across the blood brain barrier
CA2553955C (en) 2004-02-10 2012-08-28 Zystor Therapeutics, Inc. Acid alpha-glucosidase and fragments thereof
ES2629853T3 (es) 2008-05-07 2017-08-16 Biomarin Pharmaceutical Inc. Péptidos de dirección lisosómica y usos de los mismos
EP2475376B1 (de) 2009-06-17 2016-03-30 BioMarin Pharmaceutical Inc. Formulierungen für lysosomale enzyme
CN102234638B (zh) * 2010-04-27 2013-03-27 香港中文大学 修饰的玉米核糖体失活蛋白前体及其应用和蛋白纯化方法
US10347262B2 (en) 2017-10-18 2019-07-09 The Nielsen Company (Us), Llc Systems and methods to improve timestamp transition resolution
EP3758686B1 (de) * 2018-02-26 2024-11-06 R.P. Scherer Technologies, LLC Pharmazeutische darreichungsform für eine emulsion aus simethicon und loperamid
CN110455903A (zh) * 2018-05-07 2019-11-15 天士力生物医药股份有限公司 一种注射用重组人尿激酶原杂质分析的梯度电泳检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE68703T1 (de) * 1984-02-08 1991-11-15 Cetus Corp Toxinkonjugate.
ATE87318T1 (de) * 1985-11-29 1993-04-15 Consolidated Pharmaceuticals L Ricin-antikoerper-konjugate.
FR2601679B1 (fr) * 1986-07-15 1990-05-25 Sanofi Sa Immunotoxines, procede de preparation et compositions pharmaceutiques en contenant
DE3724323C2 (de) * 1986-07-29 1995-07-20 Erba Farmitalia Ein neuer Inhibitor für die Proteinsynthese
US4869903A (en) * 1987-05-29 1989-09-26 Genelabs Incorporated Method of selectively inhibiting HIV
GB8801877D0 (en) * 1988-01-28 1988-02-24 Erba Carlo Spa Nucleotide sequence encoding plant ribosome inactivating protein
IT1229216B (it) * 1989-03-31 1991-07-25 Italfarmaco Spa Proteine inibenti i ribosomi e loro derivati.
AU654563B2 (en) * 1991-07-24 1994-11-10 Imperial Chemical Industries Plc Proteins

Also Published As

Publication number Publication date
CA2044201A1 (en) 1991-12-12
HUT58800A (en) 1992-03-30
EP0466222A1 (de) 1992-01-15
DE69131589D1 (de) 1999-10-14
AU638133B2 (en) 1993-06-17
BR9102418A (pt) 1992-01-14
US5248606A (en) 1993-09-28
AU7832991A (en) 1991-12-12
CN1062172A (zh) 1992-06-24
EP0466222B1 (de) 1999-09-08
HU911944D0 (en) 1991-12-30
JPH04279599A (ja) 1992-10-05
DE69131589T2 (de) 2000-05-04

Similar Documents

Publication Publication Date Title
DE69131589D1 (de) Ribosomen-inaktivierende Proteine, inaktive Vorläuferformen derselben, Verfahren zur Herstellung und eine Methode zur Nutzung
DE3888274D1 (de) Vorrichtung zur intensiven und kontrollierten Herstellung von Mikroorganismen durch Photosynthese.
ATE309369T1 (de) Heterologe herstellung von polyketiden
DE60133802D1 (de) Verwendung von säurestabilen proteasen in tierfutter
DE60029566D1 (de) In-vitro herstellung von transplantierbarem knorpelgewebe
DK0642580T3 (da) Hepactocytvækstfaktorvarianter
DE3789881D1 (de) Verfahren zur Herstellung von Photomasken und Photomaske.
DE3888393D1 (de) BICMOS-Verfahren zur Herstellung selbstausrichtender NPN-Emitter und -Basen sowie MOSFET-Sources und -Drains.
ATE89349T1 (de) Enzymatische behandlung von wolle.
DE3883408D1 (de) Verfahren zur Herstellung von Avermectinen und die verwendeten Kulturen.
DE3680632D1 (de) Verfahren zur herstellung von kohlenstoffasern und diese kohlenstoffasern.
ATE283241T1 (de) Mittel zur herstellung von aquarien- und gartenteichwasser und verwendung davon
ATE71658T1 (de) Verfahren zur herstellung von humanlysozym.
ATE95836T1 (de) Zum abbau von glycosaminoglycan faehige enzymzusammensetzung und verfahren zur herstellung dieser zusammensetzung.
DE68916266D1 (de) Methode zur Herstellung und Stabilisierung von Halosilanen mit Acrylfunktionen.
DE69007449D1 (de) Verfahren zur Herstellung von Leistungsmos- und Halbleiteranordnungen und damit hergestellten Anordnungen.
DE59207095D1 (de) Verfahren zur Herstellung von aktiviertem Protein C
DE69902714D1 (de) Verfahren zur Herstellung von Naturkautschuk und damit erhaltener Naturkautschuk
ATE96846T1 (de) Verfahren zur herstellung von proteinhydrolysaten mit niedrigem gehalt an bitterstoffen.
ATE83480T1 (de) Cyclisches peptid, seine herstellung und seine verwendung zur behandlung von cardiovasculaeren stoerungen.
DE68919282D1 (de) Verfahren zur Herstellung von Cephalosporin und Zwischenverbindungen.
DE69313297D1 (de) Benzofuranone, benzodifurantrione und verfahren zur herstellung von benzodifurandionen
DE59106876D1 (de) Verfahren zur enzymatischen Herstellung optisch aktiver Cyanhydrine.
ATE86984T1 (de) Verfahren zur herstellung von 5,6-substituierten- 2,4-chinazolindiaminen und zwischenprodukten.
ES2076141T3 (es) 5-aril-3h-1,2,4-triazol-3-onas y su uso como anticonvulsivos.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties