ATE184289T1 - Ribosomen-inaktivierende proteine, inaktive vorläuferformen derselben, verfahren zur herstellung und eine methode zur nutzung - Google Patents
Ribosomen-inaktivierende proteine, inaktive vorläuferformen derselben, verfahren zur herstellung und eine methode zur nutzungInfo
- Publication number
- ATE184289T1 ATE184289T1 AT91201436T AT91201436T ATE184289T1 AT E184289 T1 ATE184289 T1 AT E184289T1 AT 91201436 T AT91201436 T AT 91201436T AT 91201436 T AT91201436 T AT 91201436T AT E184289 T1 ATE184289 T1 AT E184289T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- ribosome
- inactivative
- production
- precursor forms
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 239000002243 precursor Substances 0.000 title 1
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 108090000829 Ribosome Inactivating Proteins Proteins 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/535,636 US5248606A (en) | 1990-06-11 | 1990-06-11 | Dna encoding inactive precursor and active forms of maize ribosome inactivating protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE184289T1 true ATE184289T1 (de) | 1999-09-15 |
Family
ID=24135102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91201436T ATE184289T1 (de) | 1990-06-11 | 1991-06-10 | Ribosomen-inaktivierende proteine, inaktive vorläuferformen derselben, verfahren zur herstellung und eine methode zur nutzung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5248606A (de) |
| EP (1) | EP0466222B1 (de) |
| JP (1) | JPH04279599A (de) |
| CN (1) | CN1062172A (de) |
| AT (1) | ATE184289T1 (de) |
| AU (1) | AU638133B2 (de) |
| BR (1) | BR9102418A (de) |
| CA (1) | CA2044201A1 (de) |
| DE (1) | DE69131589T2 (de) |
| HU (1) | HUT58800A (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5672683A (en) * | 1989-09-07 | 1997-09-30 | Alkermes, Inc. | Transferrin neuropharmaceutical agent fusion protein |
| US5635384A (en) * | 1990-06-11 | 1997-06-03 | Dowelanco | Ribosome-inactivating proteins, inactive precursor forms thereof, a process for making and a method of using |
| DE4040954C2 (de) * | 1990-12-20 | 2001-05-17 | Max Planck Gesellschaft | Verfahren zur Erzeugung von pathogen-resistenten Pflanzen |
| JPH07504654A (ja) * | 1992-03-11 | 1995-05-25 | ナルヘックス リミテッド | オキソ及びヒドロキシ置換炭化水素のアミン誘導体 |
| US5888992A (en) * | 1992-03-11 | 1999-03-30 | Narhex Limited | Polar substituted hydrocarbons |
| MXPA93002392A (es) | 1992-03-11 | 2005-02-04 | Narhex Ltd | Derivados amino de hidrocarburos-oxo e hidroxi-substituidos. |
| US6071895A (en) * | 1992-03-11 | 2000-06-06 | Narhex Limited | Polar-substituted hydrocarbons |
| GB9304905D0 (en) * | 1992-03-16 | 1993-04-28 | Zeneca Ltd | Processes |
| JPH07507926A (ja) * | 1992-06-16 | 1995-09-07 | ホイツテイアー・インステイテユート・フオー・ダイアビテイーズ・アンド・エンドクリノロジー | サポリン含有タンパク質の組換え産生 |
| US5332808A (en) * | 1992-09-08 | 1994-07-26 | North Carolina State University | DNA encoding a ribosome inactivating protein |
| KR970001565B1 (ko) * | 1993-08-28 | 1997-02-11 | 장기하 | 섬자리공 항바이러스성 단백질(pip) 유전자 및 이를 발현하는 미생물 |
| EG23907A (en) * | 1994-08-01 | 2007-12-30 | Delta & Pine Land Co | Control of plant gene expression |
| JPH0856655A (ja) * | 1994-08-16 | 1996-03-05 | Frontier:Kk | 細胞致死剤および細胞死抑制剤 |
| US6333303B1 (en) * | 1996-04-30 | 2001-12-25 | Twinstrand Therapeutics Inc. | Antiviral ricin-like proteins |
| US6593132B1 (en) | 1997-04-30 | 2003-07-15 | Twinstrand Therapeutics Inc. | Ricin-like toxin variants for treatment of cancer, viral or parasitic infections |
| US7247715B2 (en) | 1997-04-30 | 2007-07-24 | Twinstrand Therapeutics Inc. | Ricin-like toxin variants for treatment of cancer, viral or parasitic infections |
| EP0948347A4 (de) * | 1997-07-16 | 2000-08-30 | Sophie Chen | Anti-virale und anti-tumor wirkstoffe |
| WO2000039291A1 (en) * | 1998-12-31 | 2000-07-06 | Rutgers, The State University | Virus-resistant transgenic plants expressing l3 |
| US6531125B1 (en) | 1999-03-02 | 2003-03-11 | Twinstrand Therapeutics Inc. | Antiviral ricin-like proteins |
| AU7636800A (en) | 1999-10-04 | 2001-05-10 | Twinstrand Therapeutics Inc. | Improved ricin-like toxins for treatment of cancer |
| GB0025225D0 (en) * | 2000-10-14 | 2000-11-29 | Cambridge Advanced Tech | Plant cell death system |
| AU2006201828B2 (en) * | 2000-10-14 | 2009-07-16 | British American Tobacco (Investments) Limited | Plant cell death system |
| GB0025217D0 (en) * | 2000-10-14 | 2000-11-29 | Cambridge Advanced Tech | Plant cell death system |
| US7560424B2 (en) | 2001-04-30 | 2009-07-14 | Zystor Therapeutics, Inc. | Targeted therapeutic proteins |
| US7629309B2 (en) | 2002-05-29 | 2009-12-08 | Zystor Therapeutics, Inc. | Targeted therapeutic proteins |
| EP1394250A1 (de) * | 2001-05-11 | 2004-03-03 | Kazunari Taira | Verfahren zur bildung eines stabilen komplexes des transkriptionsprodukts einer ein willkürliches peptid codierenden dna mit dem translationsprodukt, in dem verfahren eingesetztes nukleinsäurekonstrukt, durch das verfahren gebildeter komplex sowie screening auf funktionelles protein und das protein codierende mrna oder dna unter verwendung des verfahrens |
| US20030072761A1 (en) | 2001-10-16 | 2003-04-17 | Lebowitz Jonathan | Methods and compositions for targeting proteins across the blood brain barrier |
| CN1922313B (zh) | 2004-02-10 | 2011-10-26 | 生物马林医药公司 | 酸性α-糖苷酶及其片段 |
| HRP20170698T1 (hr) | 2008-05-07 | 2017-09-22 | Biomarin Pharmaceutical Inc. | Lizosomski usmjereni peptidi i njihove uporabe |
| EP2475376B1 (de) | 2009-06-17 | 2016-03-30 | BioMarin Pharmaceutical Inc. | Formulierungen für lysosomale enzyme |
| CN102234638B (zh) * | 2010-04-27 | 2013-03-27 | 香港中文大学 | 修饰的玉米核糖体失活蛋白前体及其应用和蛋白纯化方法 |
| US10347262B2 (en) | 2017-10-18 | 2019-07-09 | The Nielsen Company (Us), Llc | Systems and methods to improve timestamp transition resolution |
| EP3758686B1 (de) * | 2018-02-26 | 2024-11-06 | R.P. Scherer Technologies, LLC | Pharmazeutische darreichungsform für eine emulsion aus simethicon und loperamid |
| CN110455903A (zh) * | 2018-05-07 | 2019-11-15 | 天士力生物医药股份有限公司 | 一种注射用重组人尿激酶原杂质分析的梯度电泳检测方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE68703T1 (de) * | 1984-02-08 | 1991-11-15 | Cetus Corp | Toxinkonjugate. |
| ATE87318T1 (de) * | 1985-11-29 | 1993-04-15 | Consolidated Pharmaceuticals L | Ricin-antikoerper-konjugate. |
| FR2601679B1 (fr) * | 1986-07-15 | 1990-05-25 | Sanofi Sa | Immunotoxines, procede de preparation et compositions pharmaceutiques en contenant |
| DE3724323C2 (de) * | 1986-07-29 | 1995-07-20 | Erba Farmitalia | Ein neuer Inhibitor für die Proteinsynthese |
| US4869903A (en) * | 1987-05-29 | 1989-09-26 | Genelabs Incorporated | Method of selectively inhibiting HIV |
| GB8801877D0 (en) * | 1988-01-28 | 1988-02-24 | Erba Carlo Spa | Nucleotide sequence encoding plant ribosome inactivating protein |
| IT1229216B (it) * | 1989-03-31 | 1991-07-25 | Italfarmaco Spa | Proteine inibenti i ribosomi e loro derivati. |
| AU654563B2 (en) * | 1991-07-24 | 1994-11-10 | Imperial Chemical Industries Plc | Proteins |
-
1990
- 1990-06-11 US US07/535,636 patent/US5248606A/en not_active Expired - Fee Related
-
1991
- 1991-06-10 CA CA002044201A patent/CA2044201A1/en not_active Abandoned
- 1991-06-10 DE DE69131589T patent/DE69131589T2/de not_active Expired - Lifetime
- 1991-06-10 AT AT91201436T patent/ATE184289T1/de not_active IP Right Cessation
- 1991-06-10 EP EP91201436A patent/EP0466222B1/de not_active Expired - Lifetime
- 1991-06-11 JP JP3139171A patent/JPH04279599A/ja active Pending
- 1991-06-11 HU HU911944A patent/HUT58800A/hu unknown
- 1991-06-11 CN CN91104857A patent/CN1062172A/zh active Pending
- 1991-06-11 BR BR919102418A patent/BR9102418A/pt unknown
- 1991-06-11 AU AU78329/91A patent/AU638133B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN1062172A (zh) | 1992-06-24 |
| EP0466222B1 (de) | 1999-09-08 |
| BR9102418A (pt) | 1992-01-14 |
| HU911944D0 (en) | 1991-12-30 |
| AU7832991A (en) | 1991-12-12 |
| DE69131589D1 (de) | 1999-10-14 |
| EP0466222A1 (de) | 1992-01-15 |
| US5248606A (en) | 1993-09-28 |
| HUT58800A (en) | 1992-03-30 |
| JPH04279599A (ja) | 1992-10-05 |
| DE69131589T2 (de) | 2000-05-04 |
| AU638133B2 (en) | 1993-06-17 |
| CA2044201A1 (en) | 1991-12-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE184289T1 (de) | Ribosomen-inaktivierende proteine, inaktive vorläuferformen derselben, verfahren zur herstellung und eine methode zur nutzung | |
| DE3888274D1 (de) | Vorrichtung zur intensiven und kontrollierten Herstellung von Mikroorganismen durch Photosynthese. | |
| DE60133802D1 (de) | Verwendung von säurestabilen proteasen in tierfutter | |
| DE60029566D1 (de) | In-vitro herstellung von transplantierbarem knorpelgewebe | |
| DE68911299D1 (de) | Enzymelektrode und verfahren zur herstellung. | |
| DE3789881D1 (de) | Verfahren zur Herstellung von Photomasken und Photomaske. | |
| DE3863170D1 (de) | Mesophasenpech zur herstellung von kohlenstoffkoerpern und verfahren zur herstellung derselben. | |
| DE60114865D1 (de) | Heterologe herstellung von polyketiden | |
| DE69406559D1 (de) | Integriertes Verfahren zur Herstellung von Brenngas und Sauerstoff enthaltenden organischen Produkten | |
| DE3888393D1 (de) | BICMOS-Verfahren zur Herstellung selbstausrichtender NPN-Emitter und -Basen sowie MOSFET-Sources und -Drains. | |
| ATE89349T1 (de) | Enzymatische behandlung von wolle. | |
| DE3883408D1 (de) | Verfahren zur Herstellung von Avermectinen und die verwendeten Kulturen. | |
| DE3680632D1 (de) | Verfahren zur herstellung von kohlenstoffasern und diese kohlenstoffasern. | |
| ATE283241T1 (de) | Mittel zur herstellung von aquarien- und gartenteichwasser und verwendung davon | |
| ATE71658T1 (de) | Verfahren zur herstellung von humanlysozym. | |
| DE68902893D1 (de) | Gefrorenes produkt und herstellungsverfahren. | |
| DE3777367D1 (de) | Hirudin-variante, deren verwendung und herstellung. | |
| DE68916266D1 (de) | Methode zur Herstellung und Stabilisierung von Halosilanen mit Acrylfunktionen. | |
| DE59207095D1 (de) | Verfahren zur Herstellung von aktiviertem Protein C | |
| DE69902714D1 (de) | Verfahren zur Herstellung von Naturkautschuk und damit erhaltener Naturkautschuk | |
| ATE83480T1 (de) | Cyclisches peptid, seine herstellung und seine verwendung zur behandlung von cardiovasculaeren stoerungen. | |
| DE68919282D1 (de) | Verfahren zur Herstellung von Cephalosporin und Zwischenverbindungen. | |
| DK0384303T3 (da) | Fremgangsmåde til fremstilling af proteinhydrolysater med lavt indhold af bitterstoffer | |
| DE69313297D1 (de) | Benzofuranone, benzodifurantrione und verfahren zur herstellung von benzodifurandionen | |
| DE59106876D1 (de) | Verfahren zur enzymatischen Herstellung optisch aktiver Cyanhydrine. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |