ATE184605T1 - Methotrexat-derivate - Google Patents

Methotrexat-derivate

Info

Publication number
ATE184605T1
ATE184605T1 AT94903046T AT94903046T ATE184605T1 AT E184605 T1 ATE184605 T1 AT E184605T1 AT 94903046 T AT94903046 T AT 94903046T AT 94903046 T AT94903046 T AT 94903046T AT E184605 T1 ATE184605 T1 AT E184605T1
Authority
AT
Austria
Prior art keywords
methotrexate derivatives
antirheumatic
chem
alkyl
salt
Prior art date
Application number
AT94903046T
Other languages
English (en)
Inventor
Nobuhiro Ohi
Hiroshi Suzuki
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE184605T1 publication Critical patent/ATE184605T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT94903046T 1992-12-25 1993-12-24 Methotrexat-derivate ATE184605T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP36202792 1992-12-25

Publications (1)

Publication Number Publication Date
ATE184605T1 true ATE184605T1 (de) 1999-10-15

Family

ID=18475662

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94903046T ATE184605T1 (de) 1992-12-25 1993-12-24 Methotrexat-derivate

Country Status (13)

Country Link
US (1) US5728692A (de)
EP (1) EP0676399B1 (de)
KR (1) KR100259742B1 (de)
CN (1) CN1037771C (de)
AT (1) ATE184605T1 (de)
AU (1) AU5715894A (de)
CA (1) CA2152485A1 (de)
DE (1) DE69326479T2 (de)
DK (1) DK0676399T3 (de)
ES (1) ES2140524T3 (de)
GR (1) GR3031864T3 (de)
SG (1) SG52733A1 (de)
WO (1) WO1994014810A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100400509B1 (ko) * 1995-03-27 2004-04-03 쥬가이 세이야쿠 가부시키가이샤 메토트렉세이트유도체를함유하는약제
WO1997034606A1 (en) * 1996-03-19 1997-09-25 Chugai Seiyaku Kabushiki Kaisha Uveitis remedy
WO2000000492A1 (en) * 1998-06-26 2000-01-06 Chugai Seiyaku Kabushiki Kaisha FINE POWDER OF L-α-AMINOADIPIC ACID DERIVATIVE, ORAL SOLID PREPARATIONS CONTAINING THE SAME, AND METHOD FOR TREATMENT OF BULK POWDERS
JP3845307B2 (ja) * 1999-08-17 2006-11-15 中外製薬株式会社 心筋梗塞治療薬
US20060039985A1 (en) * 2004-04-27 2006-02-23 Bennett David B Methotrexate compositions
US7741317B2 (en) * 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
WO2009114325A2 (en) 2008-03-03 2009-09-17 Tosk, Incorporated Methotrexate adjuvants to reduce toxicity and methods for using the same
EP2527322A1 (de) 2011-05-24 2012-11-28 Noscira, S.A. Carbamylalkylphenyldisulfidderivate und deren therapeutische Verwendungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2784670B2 (ja) * 1989-08-09 1998-08-06 株式会社シーエスケイ パチンコ景品交換システム
SG49917A1 (en) * 1990-08-14 1998-06-15 Chugai Pharmaceutical Co Ltd Novel methotrexate derivatives
JPH04368385A (ja) * 1991-06-12 1992-12-21 Chugai Pharmaceut Co Ltd 新規メトトレキセート誘導体
CA2128205C (en) * 1992-01-27 2004-03-30 Hiroharu Matsuoka Methotrexate derivatives
JP3281099B2 (ja) * 1992-02-13 2002-05-13 中外製薬株式会社 抗リウマチ剤

Also Published As

Publication number Publication date
EP0676399A1 (de) 1995-10-11
AU5715894A (en) 1994-07-19
CN1037771C (zh) 1998-03-18
SG52733A1 (en) 1998-09-28
DE69326479T2 (de) 2000-03-02
WO1994014810A1 (fr) 1994-07-07
DE69326479D1 (de) 1999-10-21
KR100259742B1 (ko) 2000-07-01
EP0676399A4 (de) 1996-04-17
DK0676399T3 (da) 2000-03-20
GR3031864T3 (en) 2000-02-29
US5728692A (en) 1998-03-17
EP0676399B1 (de) 1999-09-15
CN1093365A (zh) 1994-10-12
ES2140524T3 (es) 2000-03-01
CA2152485A1 (en) 1994-07-07
KR960700245A (ko) 1996-01-19

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee