ATE185810T1 - Oligosid-derivate, verfahren zu ihrer herstellung und ihre verwendung - Google Patents

Oligosid-derivate, verfahren zu ihrer herstellung und ihre verwendung

Info

Publication number
ATE185810T1
ATE185810T1 AT95923392T AT95923392T ATE185810T1 AT E185810 T1 ATE185810 T1 AT E185810T1 AT 95923392 T AT95923392 T AT 95923392T AT 95923392 T AT95923392 T AT 95923392T AT E185810 T1 ATE185810 T1 AT E185810T1
Authority
AT
Austria
Prior art keywords
intermediary
molecule
functional groups
production
oligosides
Prior art date
Application number
AT95923392T
Other languages
English (en)
Inventor
Michel Monsigny
Annie-Claude Roche
Nadia Sdiqui
Roger Mayer
Original Assignee
Idm Immuno Designed Molecules
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idm Immuno Designed Molecules filed Critical Idm Immuno Designed Molecules
Application granted granted Critical
Publication of ATE185810T1 publication Critical patent/ATE185810T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044—Pyrrole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT95923392T 1994-06-23 1995-06-15 Oligosid-derivate, verfahren zu ihrer herstellung und ihre verwendung ATE185810T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9407738A FR2721612B1 (fr) 1994-06-23 1994-06-23 Nouveaux dérivés d'oligosides, leur procédé de préparation et leurs applications.

Publications (1)

Publication Number Publication Date
ATE185810T1 true ATE185810T1 (de) 1999-11-15

Family

ID=9464582

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95923392T ATE185810T1 (de) 1994-06-23 1995-06-15 Oligosid-derivate, verfahren zu ihrer herstellung und ihre verwendung

Country Status (8)

Country Link
US (1) US6251858B1 (de)
EP (1) EP0766689B1 (de)
JP (1) JP3553075B2 (de)
AT (1) ATE185810T1 (de)
AU (1) AU705200B2 (de)
DE (1) DE69512912T2 (de)
FR (1) FR2721612B1 (de)
WO (1) WO1996000229A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7001994B2 (en) * 2001-01-18 2006-02-21 Genzyme Corporation Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins
US7723296B2 (en) 2001-01-18 2010-05-25 Genzyme Corporation Methods for introducing mannose-6-phosphate and other oligosaccharides onto glycoproteins and its application thereof
KR100601986B1 (ko) * 2005-02-02 2006-07-18 삼성전자주식회사 유전자를 혼성화하는 방법
WO2008089403A2 (en) 2007-01-18 2008-07-24 Genzyme Corporation Oligosaccharides comprising an aminooxy group and conjugates thereof
CN102369023A (zh) 2008-12-16 2012-03-07 建新公司 寡糖-蛋白缀合物
US20240050582A1 (en) * 2021-03-08 2024-02-15 Universiteit Gent Conjugates including multiple saccharidic chains on a linear protein and uses in mammals feed

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2277823A1 (fr) * 1974-07-08 1976-02-06 Santerre Orsan N-osides de l'acide l pyrrolidone-2 carboxylique-5, derives de ceux-ci et compositions cosmetiques en comportant application
US4478744A (en) * 1982-01-25 1984-10-23 Sherwood Medical Company Method of obtaining antibodies
DE3624376A1 (de) * 1986-07-18 1988-01-28 Horst Prof Dr Kunz Glycosylamine und deren n-alkyliden-derivate
US5028594A (en) * 1988-12-27 1991-07-02 Naxcor Use of photodynamic compositions for cytotoxic effects
EP0666923A1 (de) * 1991-09-05 1995-08-16 The University Of Connecticut Gezielte bereitstellung von poly- oder oligonukleotiden in zellen
AU4993893A (en) * 1992-07-31 1994-03-03 Neose Pharmaceuticals, Inc. Compositions for treating and inhibiting gastric and duodenal ulcers

Also Published As

Publication number Publication date
JP3553075B2 (ja) 2004-08-11
JPH10502068A (ja) 1998-02-24
US6251858B1 (en) 2001-06-26
WO1996000229A1 (fr) 1996-01-04
AU705200B2 (en) 1999-05-20
AU2796295A (en) 1996-01-19
EP0766689A1 (de) 1997-04-09
FR2721612B1 (fr) 1996-08-09
DE69512912T2 (de) 2000-05-11
DE69512912D1 (de) 1999-11-25
EP0766689B1 (de) 1999-10-20
FR2721612A1 (fr) 1995-12-29

Similar Documents

Publication Publication Date Title
DE69031256D1 (de) Gebundene Schleifkörper, sowie Verfahren zu deren Herstellung und Verwendung
DE69821349D1 (de) Photoinitiatoren und sauerstoffaufnehmende zusammensetzungen
DE69410470D1 (de) Modifiziertes konjugiertes diencopolymer, verfahren zu dessen herstellung und zusammensetzung daraus
DE69022478D1 (de) Modifizierte Polyester-Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung.
DE3885440D1 (de) Haftgrundmittel für Proteinsubstrate, Verfahren zu deren Herstellung und Verwendung.
DE68916207D1 (de) Diamantbeschichtetes Werkzeug, Substrate dafür und Verfahren zu dessen Herstellung.
DE59307910D1 (de) Reaktivfarbstoffe, Verfahren zu deren Herstellung und deren Verwendung
ATE73758T1 (de) 2,2-difluorcyclopropylethanderivate, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel.
DE58903791D1 (de) Peptidderivate, verfahren zu ihrer herstellung und ihre verwendung.
DE69000248D1 (de) Verwendung von interzellularen adhaesions-molekuelen und deren bindungsliganden bei der behandlung von asthma.
DE69021341D1 (de) Härtungsmittel, verfahren zu seiner herstellung und damit hergestellte härtbare zusammensetzung.
ATE77817T1 (de) 3-cyan-pyridine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung.
ATE135359T1 (de) Sulfoniumsalze und verfahren zu deren herstellung
DE69512912D1 (de) Oligosid-derivate, verfahren zu ihrer herstellung und ihre verwendung
ATE123274T1 (de) Gesinterter verbundschleifkörper, verfahren zu seiner herstellung sowie dessen verwendung.
YU63696A (sh) Novi fenilamidin-derivati, postupci za njihovo pripremanje i njihova primena kao lekova
DE69510756D1 (de) Kautschukmischung, Verfahren zu deren Herstellung und Verwendung
DE69626251D1 (de) Wasserdispergierbare druckempfindliche klebstoffzusammensetzung, verfahren zu deren herstellung und daraus hergestellte druckempfindliche klebeartikel
DE69227241D1 (de) Blatt aus fasermaterial als informationsträger, verfahren und apparat zu dessen herstellung
ATE79121T1 (de) Iodierte polymere, verfahren zu ihrer herstellung und ihre verwendung als kontrastmittel.
ATE127460T1 (de) Im wesentlichen aus bisoxazolanen bestehende oxazolangemische, ein verfahren zu deren herstellung und ihre verwendung als härter für isocyanatgruppen aufweisende kunststoffvorläufer.
ATE194602T1 (de) Verfahren zur herstellung von 1,4,7,10- tetraazacyclododecan und dessen derivaten
DE59409563D1 (de) Reaktivfarbstoffe, Verfahren zu deren Herstellung und deren Verwendung
DE69414348D1 (de) Fluorenonderivate, verfahren zu ihrer herstellung sowie wiederherstellungs- und schutzmittel für zentrale und periphere nervendegenerationen
DE69630873D1 (de) Propylen-1-penten copolymerisate, verfahren zu deren herstellung und zusammensetzungen diese enthaltend

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties