PT98205A - Processo para a preparacao de novos derivados beta-lactamicos - Google Patents

Processo para a preparacao de novos derivados beta-lactamicos

Info

Publication number
PT98205A
PT98205A PT98205A PT9820591A PT98205A PT 98205 A PT98205 A PT 98205A PT 98205 A PT98205 A PT 98205A PT 9820591 A PT9820591 A PT 9820591A PT 98205 A PT98205 A PT 98205A
Authority
PT
Portugal
Prior art keywords
derivatives
lactamic
beta
preparing new
new beta
Prior art date
Application number
PT98205A
Other languages
English (en)
Other versions
PT98205B (pt
Inventor
Svend Gunnar Kaasgaard
Ulla Veitland
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PT98205A publication Critical patent/PT98205A/pt
Publication of PT98205B publication Critical patent/PT98205B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/04—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT98205A 1990-07-04 1991-07-04 Processo para a preparacao de novos derivados beta-lactamicos PT98205B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90610045 1990-07-04

Publications (2)

Publication Number Publication Date
PT98205A true PT98205A (pt) 1992-05-29
PT98205B PT98205B (pt) 1998-12-31

Family

ID=8205872

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98205A PT98205B (pt) 1990-07-04 1991-07-04 Processo para a preparacao de novos derivados beta-lactamicos

Country Status (17)

Country Link
US (1) US5525483A (pt)
EP (1) EP0537255B1 (pt)
JP (1) JP3115593B2 (pt)
KR (1) KR100222606B1 (pt)
AT (1) ATE317912T1 (pt)
AU (1) AU8208691A (pt)
CA (1) CA2086250C (pt)
CZ (1) CZ381392A3 (pt)
DE (1) DE69133509T2 (pt)
ES (1) ES2258260T3 (pt)
FI (1) FI925988A0 (pt)
NO (1) NO307710B1 (pt)
PT (1) PT98205B (pt)
RU (1) RU2136759C1 (pt)
SK (1) SK381392A3 (pt)
WO (1) WO1992001061A1 (pt)
ZA (1) ZA915142B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3345193A (en) * 1991-12-19 1993-07-19 Novo Nordisk A/S An improved method for the preparation of certain beta-lactam antibiotics
ES2135446T3 (es) * 1992-04-24 1999-11-01 Lilly Co Eli Procedimiento para la preparacion de cefalosporinas.
AU6106794A (en) * 1993-02-15 1994-08-29 Gist-Brocades N.V. An improved beta -lactam antibiotic composition
BE1007296A3 (nl) * 1993-07-19 1995-05-09 Dsm Nv Werkwijze voor de bereiding van een beta-lactamderivaat.
JPH0719083U (ja) * 1993-09-20 1995-04-04 株式会社江崎製作所 自動二輪車のヘッドパイプ
AUPM543894A0 (en) * 1994-05-04 1994-05-26 Commonwealth Scientific And Industrial Research Organisation An adjuvant
WO1995034675A1 (en) * 1994-06-10 1995-12-21 Gist-Brocades B.V. Improved acylation method for penicillins and cephalosporins
ES2139923T3 (es) * 1994-07-18 2000-02-16 Dsm Nv Procedimiento para preparar beta-lactamas a concentraciones de reaccionantes constantemente altas.
BE1009071A3 (nl) * 1995-02-02 1996-11-05 Dsm Nv Werkwijze voor de bereiding van een beta-lactam antibioticum.
EP0730036B1 (en) * 1995-02-28 2000-04-19 ACS DOBFAR S.p.A. Process for the enzymatic synthesis of beta-lactam antibiotics in the presence of an enzyme inhibitor
IT1274658B (it) * 1995-02-28 1997-07-18 Acs Dobfar Spa Procedimento enzimatico migliorato per la produzione di penicilline e cefalosporine
US5916762A (en) * 1995-03-31 1999-06-29 Chemferm V.O.F. Process for the recovery of ampicillin
DE69626842D1 (de) * 1995-12-08 2003-04-24 Dsm Nv Verfahren zur herstellung eines anitibiotkums
TW555855B (en) * 1996-07-26 2003-10-01 Bristol Myers Squibb Co Synthesis of beta-lactam antibacterials using soluble side chain esters and enzyme acylase
NL1006266C2 (nl) * 1997-06-10 1998-12-14 Chemferm Vof Werkwijze voor de bereiding van ampicilline.
NL1007302C2 (nl) * 1997-10-17 1999-04-20 Dsm Nv Werkwijze voor de bereiding van een ß-lactam antibioticum.
NL1010506C2 (nl) * 1998-11-06 2000-05-09 Dsm Nv Werkwijze voor de bereiding van bêta-lactam antibiotica.
EP1394262A1 (en) * 2002-08-30 2004-03-03 Bioferma Murcia, S.A. An enzymatic process for preparing beta-lactams
CN101448842A (zh) 2006-05-19 2009-06-03 帝斯曼知识产权资产管理有限公司 一种用于结晶头孢羟氨苄的方法
JP2010520752A (ja) * 2007-03-09 2010-06-17 ディーエスエム アイピー アセッツ ビー．ブイ． ベータ−ラクタム化合物の調製方法
CN103635586A (zh) 2011-06-23 2014-03-12 中化帝斯曼制药有限公司荷兰公司 结晶头孢氧哌唑中间体、其制备方法及其制药用途
WO2012175585A1 (en) 2011-06-23 2012-12-27 Dsm Sinochem Pharmaceuticals Netherlands B.V. Process for preparing 3'-thiosubstituted cephalosporins employing a penicillin g acylase

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3079305A (en) * 1959-09-24 1963-02-26 Bayer Ag Process for the enzymatic acylation of 6-aminopenicillanic acid
US3152050A (en) * 1962-12-27 1964-10-06 American Home Prod Enzymatic process for preparing penicillins
JPS5417030B2 (pt) * 1972-12-06 1979-06-27
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
DE3507403A1 (de) * 1985-03-02 1986-09-04 Hoechst Ag, 6230 Frankfurt Enzymatische semisynthese von ss-lactamantibiotika
ATE138690T1 (de) * 1988-04-26 1996-06-15 Gist Brocades Nv Verfahren zur enzymatischen herstellung von beta- lactamen
ES2036149A6 (es) * 1989-12-12 1993-05-01 Consejo Superior Investigacion Procedimiento de sintesis de antibioticos semiestaticos en sistemas termodinamicamente controlados agua-cosolventes organicos miscibles apolares con el empleo de penicilina g acilasa.
JP5417030B2 (ja) 2009-04-30 2014-02-12 ニスカ株式会社 シート処理装置及びこれを備えた画像形成システム

Also Published As

Publication number Publication date
FI925988L (fi) 1992-12-31
JP3115593B2 (ja) 2000-12-11
NO930006D0 (no) 1993-01-04
ZA915142B (en) 1992-05-27
CA2086250C (en) 2001-05-29
NO930006L (no) 1993-01-04
FI925988A7 (fi) 1992-12-31
DE69133509D1 (de) 2006-04-20
ATE317912T1 (de) 2006-03-15
AU8208691A (en) 1992-02-04
FI925988A0 (fi) 1992-12-31
RU2136759C1 (ru) 1999-09-10
EP0537255A1 (en) 1993-04-21
US5525483A (en) 1996-06-11
SK381392A3 (en) 1995-11-08
ES2258260T3 (es) 2006-08-16
CZ381392A3 (en) 1993-12-15
CA2086250A1 (en) 1992-01-05
PT98205B (pt) 1998-12-31
EP0537255B1 (en) 2006-02-15
KR100222606B1 (en) 1999-10-01
JPH05507623A (ja) 1993-11-04
DE69133509T2 (de) 2006-08-24
NO307710B1 (no) 2000-05-15
WO1992001061A1 (en) 1992-01-23

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920106

FG3A Patent granted, date of granting

Effective date: 19980928

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20030331