ATE186908T1 - 1,2,3,4-tetrahydro-9-akridinamine-derivate - Google Patents

1,2,3,4-tetrahydro-9-akridinamine-derivate

Info

Publication number
ATE186908T1
ATE186908T1 AT94112223T AT94112223T ATE186908T1 AT E186908 T1 ATE186908 T1 AT E186908T1 AT 94112223 T AT94112223 T AT 94112223T AT 94112223 T AT94112223 T AT 94112223T AT E186908 T1 ATE186908 T1 AT E186908T1
Authority
AT
Austria
Prior art keywords
tetrahydro
derivatives
acridiminamine
agents
cerebral
Prior art date
Application number
AT94112223T
Other languages
English (en)
Inventor
Colin Granger
Jeffrey Alan Kester
Walter Hamilton Moos
Anthony Jerome Thomas
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE186908T1 publication Critical patent/ATE186908T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)
AT94112223T 1989-07-31 1990-07-30 1,2,3,4-tetrahydro-9-akridinamine-derivate ATE186908T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/387,722 US4999430A (en) 1989-07-31 1989-07-31 Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine

Publications (1)

Publication Number Publication Date
ATE186908T1 true ATE186908T1 (de) 1999-12-15

Family

ID=23531113

Family Applications (2)

Application Number Title Priority Date Filing Date
AT90114586T ATE119885T1 (de) 1989-07-31 1990-07-30 1,2,3,4-tetrahydro-9-akridinaminderivate.
AT94112223T ATE186908T1 (de) 1989-07-31 1990-07-30 1,2,3,4-tetrahydro-9-akridinamine-derivate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT90114586T ATE119885T1 (de) 1989-07-31 1990-07-30 1,2,3,4-tetrahydro-9-akridinaminderivate.

Country Status (17)

Country Link
US (1) US4999430A (de)
EP (2) EP0411534B1 (de)
JP (1) JP2930245B2 (de)
KR (1) KR910002802A (de)
AT (2) ATE119885T1 (de)
AU (1) AU5994590A (de)
CA (1) CA2022297C (de)
DE (2) DE69033369T2 (de)
DK (2) DK0411534T3 (de)
ES (2) ES2068955T3 (de)
FI (1) FI903752A7 (de)
GR (1) GR3032539T3 (de)
IE (1) IE66823B1 (de)
NO (1) NO903359L (de)
NZ (1) NZ234672A (de)
PT (1) PT94849A (de)
ZA (1) ZA905978B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85741A (en) * 1987-03-17 1996-05-14 Hoechst Roussel Pharma Substituted tetrahydroacridines a process for their preparation and pharmaceutical compositions containing substituted alpha-amino-tetrahydroacridines
FR2640508B1 (fr) * 1988-12-19 1994-07-01 Dietlin Francois Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire
CA2029497C (en) * 1989-11-08 2002-06-04 Kunihiro Ninomiya (Deceased) 4-acylaminopyridine derivative
JP2546919B2 (ja) * 1989-11-08 1996-10-23 三菱化学株式会社 ９ーアシルアミノテトラヒドロアクリジン誘導体
US5179100A (en) * 1992-03-09 1993-01-12 Hoechst-Roussel Pharmaceuticals Inc. 4,5-dihydropyrazolo[3,4-a]acridines
US5466696A (en) * 1992-09-10 1995-11-14 Warner Lambert Company Tacrine and cytochrome P450 oxidase inhibitors and methods of use
US5422350A (en) * 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
HU213107B (en) * 1994-02-23 1997-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing acetic acid derivatives and pharmaceutical compositions containing them
GB9716879D0 (en) * 1997-08-08 1997-10-15 Shire Int Licensing Bv Treatment of attention deficit disorders
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
ES2168926B1 (es) * 1999-12-14 2003-10-16 Prous Science S A Derivados de ciclopenta- ciclohexa- y ciclohepta (b)quinoleina, procedimiento para su fabricacion, utilizacion y composicion farmaceutica correspondiente.
EP1779867A4 (de) * 2004-07-01 2009-12-02 Eisai R&D Man Co Ltd Mittel zur förderung der nervenreveneration
CN1315810C (zh) * 2004-08-30 2007-05-16 北京理工大学 哌嗪桥联他克林双体衍生物及其合成方法
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
US8901129B2 (en) 2009-12-11 2014-12-02 Genecode As Methods of facilitating neural cell survival using GDNF family ligand (GFL) mimetics or RET signaling pathway activators
AU2011215870B2 (en) 2010-02-09 2016-01-28 The Johns Hopkins University Methods and compositions for improving cognitive function
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
JP6433482B2 (ja) 2013-03-15 2018-12-05 エージンバイオ， インコーポレイテッド 認知機能を改善するための方法および組成物
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
WO2016191288A1 (en) 2015-05-22 2016-12-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4985430A (en) * 1987-12-03 1991-01-15 Mitsubishi Kasei Corporation 9-acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient

Also Published As

Publication number Publication date
DE69017789D1 (de) 1995-04-20
IE902751A1 (en) 1991-02-27
EP0628548A1 (de) 1994-12-14
DK0411534T3 (da) 1995-07-24
EP0411534B1 (de) 1995-03-15
NO903359D0 (no) 1990-07-30
ES2068955T3 (es) 1995-05-01
AU5994590A (en) 1991-01-31
ATE119885T1 (de) 1995-04-15
FI903752A7 (fi) 1991-02-01
DE69017789T2 (de) 1995-07-13
DE69033369D1 (de) 1999-12-30
NO903359L (no) 1991-02-01
JPH0366670A (ja) 1991-03-22
FI903752A0 (fi) 1990-07-27
ES2141787T3 (es) 2000-04-01
DK0628548T3 (da) 2000-05-08
EP0411534A3 (en) 1991-06-05
NZ234672A (en) 1991-11-26
IE66823B1 (en) 1996-02-07
CA2022297A1 (en) 1991-02-01
EP0411534A2 (de) 1991-02-06
EP0628548B1 (de) 1999-11-24
US4999430A (en) 1991-03-12
DE69033369T2 (de) 2000-05-11
GR3032539T3 (en) 2000-05-31
CA2022297C (en) 2001-09-18
PT94849A (pt) 1991-04-18
JP2930245B2 (ja) 1999-08-03
KR910002802A (ko) 1991-02-26
ZA905978B (en) 1992-04-29

Similar Documents

Publication Publication Date Title
ATE119885T1 (de) 1,2,3,4-tetrahydro-9-akridinaminderivate.
IT1229203B (it) Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
FI904204A0 (fi) Foerfarande foer framstaellning av cykliska aminosyraderivat och mellanprodukter.
ZA906057B (en) 4-(n-substituted amino)-2-butynyl-1-ureas and thioureas and derivatives thereof as centrally acting muscarinic agents
FI885560A0 (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten bisfenyylialkyylipiperatsiinijohdannaisten valmistamiseksi
FI900365A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten 3-fenyyli-5,6-dihydrobents/C/akridiini-7-karboksyylihappojohdannnaisten valmistamiseksi
AU653802B2 (en) Condensed diazepinones
ES2009689A6 (es) Procedimiento para preparar derivados de 3-piperidina-carbaldehido-oxima.
NO177145C (no) Analogifremgangsmåte for fremstilling av 4,5,6,7-tetrahydroisotiazolo[4,5-cÅ-pyridinderivater og isomere
CS53688A2 (en) Method of new substituted 3-phenyl-7h-thiazolo/3,2-b//1,2,4/triazine -7-ons production
ES2008421A6 (es) Procedimiento para la obtencion de derivados de la pilocarpina.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee