DK0628548T3 - 1,2,3,4-Tetraydro-acridinamin-derivater - Google Patents

1,2,3,4-Tetraydro-acridinamin-derivater

Info

Publication number
DK0628548T3
DK0628548T3 DK94112223T DK94112223T DK0628548T3 DK 0628548 T3 DK0628548 T3 DK 0628548T3 DK 94112223 T DK94112223 T DK 94112223T DK 94112223 T DK94112223 T DK 94112223T DK 0628548 T3 DK0628548 T3 DK 0628548T3
Authority
DK
Denmark
Prior art keywords
acridinamine
derivatives
tetraydro
agents
cerebral
Prior art date
Application number
DK94112223T
Other languages
English (en)
Inventor
Jeffrey Alan Kester
Colin Granger
Anthony Jerome Thomas
Walter Hamilton Moos
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of DK0628548T3 publication Critical patent/DK0628548T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK94112223T 1989-07-31 1990-07-30 1,2,3,4-Tetraydro-acridinamin-derivater DK0628548T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/387,722 US4999430A (en) 1989-07-31 1989-07-31 Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine

Publications (1)

Publication Number Publication Date
DK0628548T3 true DK0628548T3 (da) 2000-05-08

Family

ID=23531113

Family Applications (2)

Application Number Title Priority Date Filing Date
DK90114586.2T DK0411534T3 (da) 1989-07-31 1990-07-30 Derivater af 1,2,3,4-tetrahydro-9-acridinamin
DK94112223T DK0628548T3 (da) 1989-07-31 1990-07-30 1,2,3,4-Tetraydro-acridinamin-derivater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK90114586.2T DK0411534T3 (da) 1989-07-31 1990-07-30 Derivater af 1,2,3,4-tetrahydro-9-acridinamin

Country Status (17)

Country Link
US (1) US4999430A (da)
EP (2) EP0628548B1 (da)
JP (1) JP2930245B2 (da)
KR (1) KR910002802A (da)
AT (2) ATE186908T1 (da)
AU (1) AU5994590A (da)
CA (1) CA2022297C (da)
DE (2) DE69017789T2 (da)
DK (2) DK0411534T3 (da)
ES (2) ES2068955T3 (da)
FI (1) FI903752A7 (da)
GR (1) GR3032539T3 (da)
IE (1) IE66823B1 (da)
NO (1) NO903359L (da)
NZ (1) NZ234672A (da)
PT (1) PT94849A (da)
ZA (1) ZA905978B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25124A (en) * 1987-03-17 1991-02-19 Hoechst Roussel Pharma Substituted 9-amino-tetrahydro acridines and related compounds
FR2640508B1 (fr) * 1988-12-19 1994-07-01 Dietlin Francois Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire
CA2029497C (en) * 1989-11-08 2002-06-04 Kunihiro Ninomiya (Deceased) 4-acylaminopyridine derivative
JP2546919B2 (ja) * 1989-11-08 1996-10-23 三菱化学株式会社 ９ーアシルアミノテトラヒドロアクリジン誘導体
US5179100A (en) * 1992-03-09 1993-01-12 Hoechst-Roussel Pharmaceuticals Inc. 4,5-dihydropyrazolo[3,4-a]acridines
US5466696A (en) * 1992-09-10 1995-11-14 Warner Lambert Company Tacrine and cytochrome P450 oxidase inhibitors and methods of use
US5422350A (en) * 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
HU213107B (en) * 1994-02-23 1997-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing acetic acid derivatives and pharmaceutical compositions containing them
GB9716879D0 (en) * 1997-08-08 1997-10-15 Shire Int Licensing Bv Treatment of attention deficit disorders
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
ES2168926B1 (es) * 1999-12-14 2003-10-16 Prous Science S A Derivados de ciclopenta- ciclohexa- y ciclohepta (b)quinoleina, procedimiento para su fabricacion, utilizacion y composicion farmaceutica correspondiente.
EP1779867A4 (en) * 2004-07-01 2009-12-02 Eisai R&D Man Co Ltd MEANS FOR PROMOTING NERVE REVENERATION
CN1315810C (zh) * 2004-08-30 2007-05-16 北京理工大学 哌嗪桥联他克林双体衍生物及其合成方法
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
CN103180297A (zh) * 2009-12-11 2013-06-26 基因密码公司 使用gdnf家族配体(gfl)模拟剂或ret信号传导通路活化剂促进神经细胞存活的方法
EA202092673A3 (ru) 2010-02-09 2021-05-31 Дзе Джонс Хопкинс Юниверсити Способы и композиции для улучшения когнитивной функции
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
AU2014228512A1 (en) 2013-03-15 2015-10-01 Agenebio, Inc. Methods and compositions for improving cognitive function
CA2986598C (en) 2015-05-22 2023-09-26 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3889302T2 (de) * 1987-12-03 1994-10-20 Mitsubishi Chem Ind 9-(Acylamino)tetrahydroacridinderivate und wahrnehmungssteigernde Mittel davon als aktiver Wirkstoff.

Also Published As

Publication number Publication date
DE69017789D1 (de) 1995-04-20
EP0628548B1 (en) 1999-11-24
NO903359L (no) 1991-02-01
DE69033369T2 (de) 2000-05-11
IE902751A1 (en) 1991-02-27
JPH0366670A (ja) 1991-03-22
DE69017789T2 (de) 1995-07-13
CA2022297C (en) 2001-09-18
GR3032539T3 (en) 2000-05-31
ATE186908T1 (de) 1999-12-15
DK0411534T3 (da) 1995-07-24
EP0411534A2 (en) 1991-02-06
KR910002802A (ko) 1991-02-26
EP0628548A1 (en) 1994-12-14
US4999430A (en) 1991-03-12
ES2068955T3 (es) 1995-05-01
PT94849A (pt) 1991-04-18
FI903752A7 (fi) 1991-02-01
NO903359D0 (no) 1990-07-30
IE66823B1 (en) 1996-02-07
ATE119885T1 (de) 1995-04-15
ZA905978B (en) 1992-04-29
EP0411534B1 (en) 1995-03-15
ES2141787T3 (es) 2000-04-01
CA2022297A1 (en) 1991-02-01
FI903752A0 (fi) 1990-07-27
AU5994590A (en) 1991-01-31
DE69033369D1 (de) 1999-12-30
NZ234672A (en) 1991-11-26
JP2930245B2 (ja) 1999-08-03
EP0411534A3 (en) 1991-06-05

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