ATE188251T1 - T-zellenrezeptor, spezifisch für antigenpolypeptide und verwandte polynukleotide - Google Patents

T-zellenrezeptor, spezifisch für antigenpolypeptide und verwandte polynukleotide

Info

Publication number
ATE188251T1
ATE188251T1 AT93112159T AT93112159T ATE188251T1 AT E188251 T1 ATE188251 T1 AT E188251T1 AT 93112159 T AT93112159 T AT 93112159T AT 93112159 T AT93112159 T AT 93112159T AT E188251 T1 ATE188251 T1 AT E188251T1
Authority
AT
Austria
Prior art keywords
cell receptor
related polynucleotides
receptor specific
antigen polypeptides
antibodies
Prior art date
Application number
AT93112159T
Other languages
English (en)
Inventor
Mark M Davis
Stephen M Dr Hedrick
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27079355&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE188251(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Application granted granted Critical
Publication of ATE188251T1 publication Critical patent/ATE188251T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT93112159T 1984-03-01 1985-02-28 T-zellenrezeptor, spezifisch für antigenpolypeptide und verwandte polynukleotide ATE188251T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58533384A 1984-03-01 1984-03-01
US66380984A 1984-10-22 1984-10-22

Publications (1)

Publication Number Publication Date
ATE188251T1 true ATE188251T1 (de) 2000-01-15

Family

ID=27079355

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93112159T ATE188251T1 (de) 1984-03-01 1985-02-28 T-zellenrezeptor, spezifisch für antigenpolypeptide und verwandte polynukleotide

Country Status (7)

Country Link
US (3) US5316925A (de)
EP (3) EP0570027B1 (de)
JP (7) JPH06225765A (de)
AT (1) ATE188251T1 (de)
DE (3) DE3584209T2 (de)
SG (1) SG70553A1 (de)
WO (1) WO1985003947A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713332A (en) * 1984-01-13 1987-12-15 The Ontario Cancer Institute T cell specific CDNA clone
DE3584209T2 (de) 1984-03-01 1995-05-04 Univ Leland Stanford Junior T-zellenrezeptor, spezifisch für antigenpolypeptide und verwandte polynukleotide.
US4873190A (en) * 1984-06-13 1989-10-10 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor
US4874845A (en) * 1984-06-13 1989-10-17 Massachusetts Institute Of Technology T lymphocyte receptor subunit
US5189147A (en) * 1984-06-13 1993-02-23 Massachusetts Institute Of Technology Meterodimeric T lymphocyte receptor antibody
EP0296786B1 (de) * 1987-06-23 1996-10-30 The Board Of Trustees Of The Leland Stanford Junior University Innerhalb des alpha-Locus gelegenes T-Zell-Rezeptor-Gen und DNA-Konstruktionen
US5336603A (en) * 1987-10-02 1994-08-09 Genentech, Inc. CD4 adheson variants
US6710169B2 (en) 1987-10-02 2004-03-23 Genentech, Inc. Adheson variants
US6413516B1 (en) * 1989-03-21 2002-07-02 The Immune Response Corporation Peptides and methods against psoriasis
US6464978B1 (en) 1989-03-21 2002-10-15 The Immune Response Corporation Vaccination and methods against multiple sclerosis resulting from pathogenic responses by specific T cell populations
US5776459A (en) * 1989-07-19 1998-07-07 Connetics Corporation TCR V beta 5 peptides
US5614192A (en) * 1989-07-19 1997-03-25 Connective Therapeutics, Inc. T cell receptor peptides as therapeutics for immune-related disease
US6416971B1 (en) * 1990-05-15 2002-07-09 E.R. Squibb & Sons, Inc. Soluble single chain T cell receptors
US7294712B2 (en) * 1990-06-04 2007-11-13 Aventis Pharma S.A. Nucleotide sequences coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
IE920447A1 (en) * 1991-02-12 1992-08-12 Roussel Uclaf NUCLEOTIDE SEQUENCES CODING FOR ß-CHAIN VARIABLE REGIONS OF¹HUMAN T-LYMPHOCYTE RECEPTORS, CORRESPONDING PEPTIDE SEGMENTS¹AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
US5552300A (en) * 1994-01-13 1996-09-03 T Cell Sciences, Inc. T cell antigen receptor V region proteins and methods of preparation thereof
US6451571B1 (en) 1994-05-02 2002-09-17 University Of Washington Thymidine kinase mutants
US5688690A (en) * 1994-09-16 1997-11-18 The Wistar Institute Of Anatomy And Biology Human cytotoxic lymphocyte signal transduction surface protein (P38) and monoclonal antibodies thereto
US6087096A (en) * 1995-11-13 2000-07-11 Dau; Peter C. Method of intrafamily fragment analysis of the T cell receptor α and β chain CDR3 regions
AU9186598A (en) * 1997-09-26 1999-04-23 Kyowa Hakko Kogyo Co. Ltd. Killer t cell receptor recognizing human immunodeficiency virus
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
DE19816129A1 (de) * 1998-04-09 1999-10-14 Dolores Schendel T-Zellrezeptor-Expressionskassette
AU2002220275A1 (en) * 2000-12-08 2002-06-18 The Board Of Trustees Of The University Of Illinois Mutated class ii major histocompatibility proteins
DE10109855A1 (de) * 2001-03-01 2002-09-12 Stanislawski Thomas Polypeptide eines p53-Protein-spezifischen murinen alpha/beta T-Zell Rezeptors, diese kodierende Nukleinsäuren und deren Verwendung
US20030199092A1 (en) * 2002-01-11 2003-10-23 The Regents Of The University Of California Methods for increasing mRNA half-life in eukaryotic cells
KR20130105885A (ko) 2005-01-05 2013-09-26 에프-스타 비오테크놀로기쉐 포르슝스 운드 엔트비클룽스게스.엠.베.하. 상보성 결정부위와 다른 분자의 부위에서 처리된 결합성을 갖는 합성 면역글로불린 영역
US20080064631A1 (en) * 2006-01-13 2008-03-13 Jeffrey Molldrem T-cell receptors for use in diagnosis and therapy of cancers and autoimmune disease
AT503861B1 (de) * 2006-07-05 2008-06-15 F Star Biotech Forsch & Entw Verfahren zur manipulation von t-zell-rezeptoren
AT503889B1 (de) 2006-07-05 2011-12-15 Star Biotechnologische Forschungs Und Entwicklungsges M B H F Multivalente immunglobuline
US10155038B2 (en) 2007-02-02 2018-12-18 Yale University Cells prepared by transient transfection and methods of use thereof
US8859229B2 (en) * 2007-02-02 2014-10-14 Yale University Transient transfection with RNA
US9249423B2 (en) 2007-02-02 2016-02-02 Yale University Method of de-differentiating and re-differentiating somatic cells using RNA
WO2009045898A2 (en) * 2007-09-28 2009-04-09 Mayo Foundation For Medical Education And Research Assessing t cell repertoires
EP2098536A1 (de) 2008-03-05 2009-09-09 4-Antibody AG Isolation und Identifikation antigen- oder ligandenspezifischer Bindungsproteine
EP2113255A1 (de) 2008-05-02 2009-11-04 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Zytotoxisches Immunglobulin
JP5829606B2 (ja) * 2009-06-29 2015-12-09 カリフォルニア・インスティテュート・オブ・テクノロジーＣａｌｉｆｏｒｎｉａ Ｉｎｓｔｉｔｕｔｅ Ｏｆｔｅｃｈｎｏｌｏｇｙ 単一細胞からの未知の再配列されたｔ細胞受容体の単離
WO2016014725A1 (en) 2014-07-22 2016-01-28 The University Of Notre Dame Du Lac Molecular constructs and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468464A (en) * 1974-11-04 1984-08-28 The Board Of Trustees Of The Leland Stanford Junior University Biologically functional molecular chimeras
US4363877B1 (en) * 1977-09-23 1998-05-26 Univ California Recombinant dna transfer vectors
US4356270A (en) * 1977-11-08 1982-10-26 Genentech, Inc. Recombinant DNA cloning vehicle
US4394443A (en) * 1980-12-18 1983-07-19 Yale University Method for cloning genes
US4446235A (en) * 1982-03-22 1984-05-01 Genentech, Inc. Method for cloning human growth hormone varient genes
US4550086A (en) * 1983-02-16 1985-10-29 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies that recognize human T cells
US4713332A (en) * 1984-01-13 1987-12-15 The Ontario Cancer Institute T cell specific CDNA clone
US4923799A (en) * 1984-02-06 1990-05-08 The Ontario Cancer Institute T cell specific cDNA clone
DE3584209T2 (de) * 1984-03-01 1995-05-04 Univ Leland Stanford Junior T-zellenrezeptor, spezifisch für antigenpolypeptide und verwandte polynukleotide.
US4874845A (en) * 1984-06-13 1989-10-17 Massachusetts Institute Of Technology T lymphocyte receptor subunit
US4873190A (en) * 1984-06-13 1989-10-10 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor

Also Published As

Publication number Publication date
JPH10210992A (ja) 1998-08-11
EP0570027A1 (de) 1993-11-18
JPH1067675A (ja) 1998-03-10
EP0174366A1 (de) 1986-03-19
JPH09121871A (ja) 1997-05-13
DE570027T1 (de) 1994-11-17
DE3588219T2 (de) 2000-05-18
HK1006855A1 (en) 1999-03-19
EP0174366A4 (de) 1987-03-26
US6180104B1 (en) 2001-01-30
US5840304A (en) 1998-11-24
SG70553A1 (en) 2000-02-22
EP0609901A1 (de) 1994-08-10
WO1985003947A1 (en) 1985-09-12
DE3584209D1 (de) 1994-12-01
EP0570027B1 (de) 1999-12-29
JPH06225765A (ja) 1994-08-16
JPH10114672A (ja) 1998-05-06
JPH07274976A (ja) 1995-10-24
EP0174366B1 (de) 1994-10-26
DE3584209T2 (de) 1995-05-04
HK1013844A1 (en) 1999-09-10
US5316925A (en) 1994-05-31
JPH1146779A (ja) 1999-02-23
DE3588219D1 (de) 2000-02-03

Similar Documents

Publication Publication Date Title
DE3588219D1 (de) T-Zellenrezeptor, spezifisch für Antigenpolypeptide und verwandte Polynukleotide
ATE177147T1 (de) Säugetier-rezeptoren für interleukin 10 (il-10)
ATE200150T1 (de) Auf einmaligen sequenzen innerhalb des veränderlichen gebiets des t-zellrezeptors basierte diagnosemittel und deren verwendung
DE69841170D1 (de) Menschliche Toll-ähliche Rezeptorproteine, zugehörige Reagenzien und Verfahren
GB2209757A (en) Altered antibodies
DE3855536D1 (de) Rezeptoren für wachstumshormone
DE68925226D1 (de) Monoklonale Antikörper
IL96043A0 (en) Polypeptides complementary to peptides or proteins having an amino acid sequence or nucleotide coding sequence at least partially known
NO913186L (no) Fremgangsmaate for anvendelse og syntese av peptider.
DE3688246D1 (de) Kunstpolypeptide zum nachweis mykobakterieller infektionen.
BR9810907A (pt) Anticorpos monoclonais e policlonais, peptìdeo suscetìvel de gerar um anticorpo, agente imunogênico, sequência de nucleotìdeos, composição farmacêutica, uso de pelo menos um anticorpo, kit de diagnóstico, e, processo para preparar um agente imunogênico
MX9705172A (es) Polipeptido asociado a il-2r y moleculas de adn que codifican el mismo.
ES2150495T3 (es) Ligandos de flt3 purificados de mamifero y agonistas y antagonistas de los mismos.
DK1181366T3 (da) Mammale receptorproteiner, beslægtede reagenser og fremgangsmåder
DE69033128D1 (de) Für leberzellkarzinom spezifisches onkogen
DE3886545D1 (de) Monoklonale human-antikörper, spezifisch für rh(d).
DK414386A (da) Monoklonalt antistof, cellelinje til fremstilling deraf og antistoffets anvendelse
NO177536C (no) HIV-1-relaterte polypeptider, preparat som omfatter en blanding med minst to polypeptider, samt diagnostisk system og anvendelse av et polypeptid for måling av anti-HIV-1-antistoffer

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
RZN Patent revoked