ATE196775T1 - Gereinigte flt3 liganden von saeugentieren, agonisten und antagonisten davon - Google Patents

Gereinigte flt3 liganden von saeugentieren, agonisten und antagonisten davon

Info

Publication number: ATE196775T1
Authority: AT; Austria
Prior art keywords: ligands; agonists; antagonists; mammal; purified
Prior art date: 1993-05-19

Application number

AT94919120T

Other languages

English (en)

Inventor

Charles H Hannum

Frank D Lee

Daniel Birnbaum

Janice A Culpepper

Original Assignee

Schering Corp

Inst Nat Sante Rech Med

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-19

Filing date

1994-05-18

Publication date

2000-10-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27568243&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE196775(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1994-05-18 Application filed by Schering Corp, Inst Nat Sante Rech Med filed Critical Schering Corp

2000-10-15 Application granted granted Critical

2000-10-15 Publication of ATE196775T1 publication Critical patent/ATE196775T1/de

Links

239000003446 ligand Substances 0.000 title abstract 3
101000932478 Homo sapiens Receptor-type tyrosine-protein kinase FLT3 Proteins 0.000 title 1
241000124008 Mammalia Species 0.000 title 1
102100020718 Receptor-type tyrosine-protein kinase FLT3 Human genes 0.000 title 1
239000000556 agonist Substances 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
150000007523 nucleic acids Chemical class 0.000 abstract 2
102000039446 nucleic acids Human genes 0.000 abstract 2
108020004707 nucleic acids Proteins 0.000 abstract 2
102100020715 Fms-related tyrosine kinase 3 ligand protein Human genes 0.000 abstract 1
101710162577 Fms-related tyrosine kinase 3 ligand protein Proteins 0.000 abstract 1
101100335081 Mus musculus Flt3 gene Proteins 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
239000012634 fragment Substances 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
108020003175 receptors Proteins 0.000 abstract 1
239000013598 vector Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Toxicology (AREA)
Zoology (AREA)
Urology & Nephrology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT94919120T 1993-05-19 1994-05-18 Gereinigte flt3 liganden von saeugentieren, agonisten und antagonisten davon ATE196775T1 (de)

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
US6523193A	1993-05-19	1993-05-19
US8926393A	1993-07-07	1993-07-07
US9254993A	1993-07-16	1993-07-16
US10634093A	1993-08-13	1993-08-13
US11239193A	1993-08-24	1993-08-24
US15511193A	1993-11-19	1993-11-19
US16241393A	1993-12-03	1993-12-03
PCT/US1994/005150 WO1994026891A2 (en)	1993-05-19	1994-05-18	Purified mammalian flt3 ligands and agonists and antagonists thereof

Publications (1)

Publication Number	Publication Date
ATE196775T1 true ATE196775T1 (de)	2000-10-15

Family

ID=27568243

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94919120T ATE196775T1 (de)	1993-05-19	1994-05-18	Gereinigte flt3 liganden von saeugentieren, agonisten und antagonisten davon

Country Status (7)

Country	Link
EP (2)	EP0699236B2 (de)
JP (1)	JPH09501822A (de)
AT (1)	ATE196775T1 (de)
AU (1)	AU7017494A (de)
DE (1)	DE69426076T3 (de)
ES (1)	ES2150495T5 (de)
WO (1)	WO1994026891A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ314644A (en) *	1993-05-24	2000-11-24	Immunex Corp	Use of flt3-ligands as a growth stimulator of stem cells in the transplantation of tissue
US7045128B2 (en)	1993-05-24	2006-05-16	Immunex Corporation	Antibodies against flt3-ligand
US7294331B2 (en)	1994-03-07	2007-11-13	Immunex Corporation	Methods of using flt3-ligand in hematopoietic cell transplantation
US5587459A (en) *	1994-08-19	1996-12-24	Regents Of The University Of Minnesota	Immunoconjugates comprising tyrosine kinase inhibitors
US5911995A (en) *	1994-08-19	1999-06-15	Regents Of The University Of Minnesota	EGF-genistein conjugates for the treatment of cancer
US7150992B1 (en)	1995-10-04	2006-12-19	Innunex Corporation	Methods of preparing dendritic cells with flt3-ligand and antigen
US7361330B2 (en)	1995-10-04	2008-04-22	Immunex Corporation	Methods of using flt3-ligand in the treatment of fibrosarcoma
US6660257B1 (en)	1996-10-25	2003-12-09	Pharmacia Corporation	Circular permuteins of flt3 ligand
US6967092B1 (en)	1996-10-25	2005-11-22	Mc Kearn John P	Multi-functional chimeric hematopoietic receptor agonists
US7112409B2 (en)	1999-01-29	2006-09-26	Center For Molecular Medicine And Immunology	Method of determining cytokine dosage for myelosuppressive state
US6649352B1 (en) *	1999-01-29	2003-11-18	Center For Molecular Medicine And Immunology	Method of evaluating myelosuppressive state
JP2014532184A (ja) *	2011-10-12	2014-12-04	ザユニバーシティオブノースカロライナアットチャペルヒルＴｈｅＵｎｉｖｅｒｓｉｔｙＯｆＮｏｒｔｈＣａｒｏｌｉｎａＡｔＣｈａｐｅｌＨｉｌｌ	多重化キナーゼ阻害剤ビーズ及びその使用
US10780121B2 (en)	2018-08-29	2020-09-22	Shattuck Labs, Inc.	FLT3L-based chimeric proteins
AU2019404098A1 (en)	2018-12-18	2021-05-27	Boehringer Ingelheim Io Canada Inc.	FLT3 agonist antibodies and uses thereof
BR112021011730A2 (pt) *	2018-12-21	2021-08-31	Ottawa Hospital Research Institute	Vetores de ortopoxvírus modificados

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0354808B1 (de) *	1988-08-12	1997-12-03	Ligand Pharmaceuticals Incorporated	Polypeptid-induzierte monoklonale Rezeptoren gegen Proteinliganden
RU2212411C2 (ru) *	1989-10-16	2003-09-20	Эмджен Инк.	Полипептид, обладающий гемопоэтической биологической активностью фактора стволовых клеток (варианты), днк (варианты), экспрессирующий вектор (варианты), фармацевтическая композиция для гемопоэтической терапии, способ получения полипептида и способ его использования (варианты)
US5185438A (en) *	1991-04-02	1993-02-09	The Trustees Of Princeton University	Nucleic acids encoding hencatoporetic stem cell receptor flk-2
US5554512A (en) *	1993-05-24	1996-09-10	Immunex Corporation	Ligands for flt3 receptors

1994
- 1994-05-18 AT AT94919120T patent/ATE196775T1/de active
- 1994-05-18 WO PCT/US1994/005150 patent/WO1994026891A2/en not_active Ceased
- 1994-05-18 JP JP6525626A patent/JPH09501822A/ja not_active Ceased
- 1994-05-18 EP EP94919120A patent/EP0699236B2/de not_active Expired - Lifetime
- 1994-05-18 ES ES94919120T patent/ES2150495T5/es not_active Expired - Lifetime
- 1994-05-18 EP EP99116598A patent/EP0992584A3/de not_active Withdrawn
- 1994-05-18 DE DE69426076T patent/DE69426076T3/de not_active Expired - Lifetime
- 1994-05-18 AU AU70174/94A patent/AU7017494A/en not_active Abandoned

Also Published As

Publication number	Publication date
EP0699236B2 (de)	2006-06-14
WO1994026891A3 (en)	1995-01-19
EP0992584A2 (de)	2000-04-12
WO1994026891A2 (en)	1994-11-24
AU7017494A (en)	1994-12-12
ES2150495T3 (es)	2000-12-01
EP0992584A3 (de)	2000-06-07
ES2150495T5 (es)	2007-02-16
DE69426076D1 (de)	2000-11-09
DE69426076T2 (de)	2001-05-10
EP0699236B1 (de)	2000-10-04
DE69426076T3 (de)	2007-01-18
JPH09501822A (ja)	1997-02-25
EP0699236A1 (de)	1996-03-06

Publication	Publication Date	Title
ATE196775T1 (de)	2000-10-15	Gereinigte flt3 liganden von saeugentieren, agonisten und antagonisten davon
DK0758383T3 (da)	2007-05-29	Oplöselige polypeptidfraktioner af LAG-3-proteinet; fremgangsmåde til fremstilling; terapeutisk sammensætning; antiidiotypisk antistof
DE69535641D1 (de)	2007-12-27	Morphogene protein-spezifische zelloberflächenrezeptoren und ihre verwendungen
DK0397633T3 (da)	1996-01-02	Fibronectinbindende protein samt fremstilling deraf
DK0673420T3 (da)	1999-10-04	Mammale receptorer for interleukin 10 (IL-10)
DE68929043D1 (de)	1999-09-09	Für androgen-rezeptor-protein kodierende dna
ATE362982T1 (de)	2007-06-15	ßDEATH-DOMAINß-ENTHALTENDER REZEPTOR 4 (DR4), EIN MITGLIED DER TNF-REZEPTOR SUPERFAMILIE, WELCHER AN TRAIL (APO-2L) BINDET
PT662827E (pt)	2002-09-30	Metodos de diagnostico e composicoes farmaceuticas a base de proteinas notch e acidos nucleicos
DE69841273D1 (de)	2009-12-17	Verfahren zur identifikation von bindestellendomänen, die ihre epitopbindefähigkeit beibehalten
DK1005540T3 (da)	2004-10-18	IKK-beta-proteiner, nukleinsyrer og fremgangsmåder
DE69435038D1 (de)	2007-12-06	Aktivin rezeptor-ähnliche kinase (alk), gehörend zur tgf rezeptorfamilie und/oder zur bmp rezeptorfamilie
NZ236511A (en)	1993-02-25	Polypeptides containing sequences from residues 61 to 82 or 104 to 129 of human il-4 or subsequences thereof; antibodies and pharmaceutical compositions
EP0686161A4 (de)	1997-07-16	Alpha untereinheit des humanen beta-2 integrins
DE69837268D1 (de)	2007-04-19	Neue moleküle aus der familie der tango-77-ähnlichen proteine und ihre verewendungen.
ATE335818T1 (de)	2006-09-15	Ligand polypeptide für hypophyse g-protein gekoppeltes rezeptor-protein, deren herstellung und anwendung
ATE353964T1 (de)	2007-03-15	Crsp-proteine (cystein-reiche, sekretierte proteine), die dafür kodierenden nukleinsäuren und ihre verwendungen
MXPA02008239A (es)	2004-08-12	Gen humano de la esquizofrenia.
DE69735207D1 (de)	2006-04-13	Neuartiges, fibrinogen-bindendes protein, welches von einem koagulase-negativen staphylokokkus abstammt
ATE179712T1 (de)	1999-05-15	Analoge für spezifische oligosaccharid-protein- wechselwirkungen und ihre verwendungen
NO882380L (no)	1988-12-02	Fibfonektin-bindende protein, samt fremstilling derav.
DE69328060D1 (de)	2000-04-20	Angiotensin-II Typ-1 Rezeptor und dessen Herstellung
DE3888031D1 (de)	1994-04-07	Homocyclostatin und Cyclostatin enthaltende Polypeptide als Antihypertensiva.
ATE78513T1 (de)	1992-08-15	Immunoglobulin-a-rezeptor-protein (arp), sowie dessen klonierung und expression.