ATE191216T1 - Analogen von acronycine, verfahren zu ihrer herstellung und sie enthaltende pharmaceutische zusammensetzungen - Google Patents

Analogen von acronycine, verfahren zu ihrer herstellung und sie enthaltende pharmaceutische zusammensetzungen

Info

Publication number: ATE191216T1
Authority: AT; Austria
Prior art keywords: alkoxy; acronycine; analogues; acyl; production
Prior art date: 1994-02-17

Application number

AT95400314T

Other languages

English (en)

Inventor

Michel Koch

Francois Tillequin

Alexios-Leandros Skaltsounis

Yves Rolland

Alain Pierre

Ghanem Atassi

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-02-17

Filing date

1995-02-15

Publication date

2000-04-15

1995-02-15 Application filed by Adir filed Critical Adir

2000-04-15 Application granted granted Critical

2000-04-15 Publication of ATE191216T1 publication Critical patent/ATE191216T1/de

Links

SMPZPKRDRQOOHT-UHFFFAOYSA-N acronycine Chemical class CN1C2=CC=CC=C2C(=O)C2=C1C(C=CC(C)(C)O1)=C1C=C2OC SMPZPKRDRQOOHT-UHFFFAOYSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
125000003545 alkoxy group Chemical group 0.000 abstract 5
125000002252 acyl group Chemical group 0.000 abstract 4
-1 diastereoisomers Chemical class 0.000 abstract 4
239000004215 Carbon black (E152) Substances 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000001475 halogen functional group Chemical group 0.000 abstract 2
229930195733 hydrocarbon Natural products 0.000 abstract 2
150000002430 hydrocarbons Chemical class 0.000 abstract 2
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
150000001204 N-oxides Chemical class 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Plant Substances (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)

AT95400314T 1994-02-17 1995-02-15 Analogen von acronycine, verfahren zu ihrer herstellung und sie enthaltende pharmaceutische zusammensetzungen ATE191216T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9401806A FR2716197B1 (fr)	1994-02-17	1994-02-17	Nouveaux analogues de l'acronycine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number	Publication Date
ATE191216T1 true ATE191216T1 (de)	2000-04-15

Family

ID=9460176

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95400314T ATE191216T1 (de)	1994-02-17	1995-02-15	Analogen von acronycine, verfahren zu ihrer herstellung und sie enthaltende pharmaceutische zusammensetzungen

Country Status (17)

Country	Link
US (1)	US5567707A (de)
EP (1)	EP0668281B1 (de)
JP (1)	JP2675271B2 (de)
CN (1)	CN1055926C (de)
AT (1)	ATE191216T1 (de)
AU (1)	AU680080B2 (de)
CA (1)	CA2142560C (de)
DE (1)	DE69515922T2 (de)
DK (1)	DK0668281T3 (de)
ES (1)	ES2146722T3 (de)
FI (1)	FI118767B (de)
FR (1)	FR2716197B1 (de)
GR (1)	GR3033003T3 (de)
NO (1)	NO308472B1 (de)
NZ (1)	NZ270509A (de)
PT (1)	PT668281E (de)
ZA (1)	ZA951334B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6130161A (en)	1997-05-30	2000-10-10	International Business Machines Corporation	Method of forming copper interconnections with enhanced electromigration resistance and reduced defect sensitivity
FR2772765B1 (fr) *	1997-12-19	2000-03-17	Adir	Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2856687B1 (fr) *	2003-06-25	2005-09-16	Servier Lab	Nouveaux derives de benzo[a]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2902792A1 (fr) *	2006-06-21	2007-12-28	Servier Lab	Nouveaux derives cinnamates de tetrahydro-7h-pyrano(2,3-c)acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3624087A (en) *	1967-07-17	1971-11-30	Lilly Co Eli	Synthesis of acronycine and related compounds
US3621041A (en) *	1968-07-05	1971-11-16	Lilly Co Eli	Chromans
US3673163A (en) *	1970-06-16	1972-06-27	Lilly Co Eli	Pharmacological preparation containing an acronycine-polyvinylprrolidone coprecipitate
US3657249A (en) *	1970-10-12	1972-04-18	Lilly Co Eli	Synthesis of nordihydroacronycine and related compounds
US3715359A (en) *	1971-07-02	1973-02-06	Lilly Co Eli	Hydroxylated acronycine
US3943137A (en) *	1973-07-09	1976-03-09	University Of Kansas Endowment Association	Acronycine derivatives

1994
- 1994-02-17 FR FR9401806A patent/FR2716197B1/fr not_active Expired - Fee Related
1995
- 1995-02-15 EP EP95400314A patent/EP0668281B1/de not_active Expired - Lifetime
- 1995-02-15 PT PT95400314T patent/PT668281E/pt unknown
- 1995-02-15 ES ES95400314T patent/ES2146722T3/es not_active Expired - Lifetime
- 1995-02-15 DE DE69515922T patent/DE69515922T2/de not_active Expired - Fee Related
- 1995-02-15 JP JP7026866A patent/JP2675271B2/ja not_active Expired - Fee Related
- 1995-02-15 CA CA002142560A patent/CA2142560C/fr not_active Expired - Fee Related
- 1995-02-15 DK DK95400314T patent/DK0668281T3/da active
- 1995-02-15 AT AT95400314T patent/ATE191216T1/de not_active IP Right Cessation
- 1995-02-15 FI FI950681A patent/FI118767B/fi active
- 1995-02-16 US US08/389,798 patent/US5567707A/en not_active Expired - Lifetime
- 1995-02-16 NO NO950574A patent/NO308472B1/no unknown
- 1995-02-16 NZ NZ270509A patent/NZ270509A/en not_active IP Right Cessation
- 1995-02-16 AU AU12287/95A patent/AU680080B2/en not_active Ceased
- 1995-02-17 CN CN95102005A patent/CN1055926C/zh not_active Expired - Fee Related
- 1995-02-17 ZA ZA951334A patent/ZA951334B/xx unknown
2000
- 2000-03-30 GR GR20000400612T patent/GR3033003T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
NZ270509A (en)	1996-03-26
NO950574D0 (no)	1995-02-16
FR2716197A1 (fr)	1995-08-18
FR2716197B1 (fr)	1996-04-19
PT668281E (pt)	2000-07-31
ES2146722T3 (es)	2000-08-16
DE69515922T2 (de)	2000-11-02
EP0668281B1 (de)	2000-03-29
DK0668281T3 (da)	2000-08-14
NO308472B1 (no)	2000-09-18
EP0668281A1 (de)	1995-08-23
GR3033003T3 (en)	2000-07-31
AU1228795A (en)	1995-08-24
CA2142560C (fr)	2002-04-09
FI950681A0 (fi)	1995-02-15
US5567707A (en)	1996-10-22
AU680080B2 (en)	1997-07-17
NO950574L (no)	1995-08-18
JPH07252257A (ja)	1995-10-03
FI118767B (fi)	2008-03-14
FI950681L (fi)	1995-08-18
CA2142560A1 (fr)	1995-08-18
DE69515922D1 (de)	2000-05-04
JP2675271B2 (ja)	1997-11-12
ZA951334B (en)	1995-10-23
CN1055926C (zh)	2000-08-30
CN1113490A (zh)	1995-12-20

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Legal Events

Date	Code	Title	Description
2000-10-15	UEP	Publication of translation of european patent specification
2009-11-15	REN	Ceased due to non-payment of the annual fee