ATE192440T1 - Verfahren zur herstellung von 1-(1,2,4-triazol-1- yl)-propan-2-ol-derivaten - Google Patents

Verfahren zur herstellung von 1-(1,2,4-triazol-1- yl)-propan-2-ol-derivaten

Info

Publication number
ATE192440T1
ATE192440T1 AT94302105T AT94302105T ATE192440T1 AT E192440 T1 ATE192440 T1 AT E192440T1 AT 94302105 T AT94302105 T AT 94302105T AT 94302105 T AT94302105 T AT 94302105T AT E192440 T1 ATE192440 T1 AT E192440T1
Authority
AT
Austria
Prior art keywords
chem
formula
triazole
derivatives
reacting
Prior art date
Application number
AT94302105T
Other languages
English (en)
Inventor
Alexander Veinberg
Alexander Senderichin
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Application granted granted Critical
Publication of ATE192440T1 publication Critical patent/ATE192440T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT94302105T 1993-03-29 1994-03-23 Verfahren zur herstellung von 1-(1,2,4-triazol-1- yl)-propan-2-ol-derivaten ATE192440T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL105200A IL105200A (en) 1993-03-29 1993-03-29 Regiospecific processes for the preparation of 1, 3-bis (1, 2, 4-triazol-1-yl)-propan- 2-ol derivatives

Publications (1)

Publication Number Publication Date
ATE192440T1 true ATE192440T1 (de) 2000-05-15

Family

ID=11064666

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94302105T ATE192440T1 (de) 1993-03-29 1994-03-23 Verfahren zur herstellung von 1-(1,2,4-triazol-1- yl)-propan-2-ol-derivaten

Country Status (15)

Country Link
US (1) US5484936A (de)
EP (1) EP0618198B1 (de)
JP (1) JPH06340637A (de)
KR (1) KR940021536A (de)
AT (1) ATE192440T1 (de)
AU (1) AU683443B2 (de)
CA (1) CA2119995A1 (de)
DE (1) DE69424215T2 (de)
DK (1) DK0618198T3 (de)
ES (1) ES2145097T3 (de)
HU (1) HUT70751A (de)
IL (1) IL105200A (de)
NZ (1) NZ260190A (de)
SK (1) SK281688B6 (de)
ZA (1) ZA942093B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ270418A (en) 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
CA2139079C (en) * 1994-12-23 1996-05-28 K.S. Keshava Murthy Commercial process for the manufacture of fluconazole and intermediates useful in the manufacture thereof
NZ272586A (en) * 1995-07-17 1996-10-28 Apotex Inc Process for preparing fluconazole and triazolylepoxypropane precursors
MXPA04011458A (es) * 2002-06-24 2005-02-14 Basf Ag Procedimiento para la obtencion de 1, 2, 4-triazolilmetil-oxiranos.
GB0900786D0 (en) * 2009-01-19 2009-03-04 Natracine Uk Ltd Therapeutic compositions
BR102013027313B1 (pt) * 2013-10-23 2019-06-18 Iharabras S.A. Indústrias Químicas Processo para a preparação seletiva de (1h-1,2,4-triazol-1-il) alcanóis, composto hidrazinil alcanol obtido por tal processo e seu uso
CN110198707A (zh) * 2016-11-28 2019-09-03 赛力克斯生物私人有限公司 用于治疗口腔感染性疾病的组合物和方法
JP7515684B2 (ja) * 2021-02-22 2024-07-12 株式会社クレハ アゾール誘導体の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU529930B2 (en) * 1979-03-07 1983-06-23 Zeneca Limited Fungicidal triazole derivatives
NZ208705A (en) * 1980-08-18 1985-09-13 Ici Plc Ethers or esters of certain 2-(1,2,4-triazol-1-yl)-1,1-disubstituted-ethanols
GB2099818A (en) * 1981-06-06 1982-12-15 Pfizer Ltd Triazoles
EP0069442B1 (de) * 1981-06-06 1985-02-20 Pfizer Limited Fungizide Mittel, Verfahren zu deren Herstellung, und diese enthaltende pharmazeutische Zusammenstellungen
IT1249211B (it) * 1990-06-08 1995-02-20 Ind Chimica Srl Processo per la preparazione di triazolil isopropanoli in particolare fluconazolo

Also Published As

Publication number Publication date
KR940021536A (ko) 1994-10-19
EP0618198B1 (de) 2000-05-03
HUT70751A (en) 1995-10-30
DE69424215T2 (de) 2000-11-30
DK0618198T3 (da) 2000-08-07
ES2145097T3 (es) 2000-07-01
NZ260190A (en) 1995-03-28
AU5907794A (en) 1994-10-06
CA2119995A1 (en) 1994-09-30
JPH06340637A (ja) 1994-12-13
ZA942093B (en) 1995-01-13
IL105200A (en) 1997-03-18
DE69424215D1 (de) 2000-06-08
US5484936A (en) 1996-01-16
IL105200A0 (en) 1993-07-08
AU683443B2 (en) 1997-11-13
EP0618198A1 (de) 1994-10-05
SK281688B6 (sk) 2001-06-11
SK34994A3 (en) 1995-02-08
HU9400871D0 (en) 1994-06-28

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties