ATE192748T1 - Neue alkaloidderivate, ihre verwendung und diese enthaltende pharmazeutische formulierungen - Google Patents

Neue alkaloidderivate, ihre verwendung und diese enthaltende pharmazeutische formulierungen

Info

Publication number
ATE192748T1
ATE192748T1 AT93304246T AT93304246T ATE192748T1 AT E192748 T1 ATE192748 T1 AT E192748T1 AT 93304246 T AT93304246 T AT 93304246T AT 93304246 T AT93304246 T AT 93304246T AT E192748 T1 ATE192748 T1 AT E192748T1
Authority
AT
Austria
Prior art keywords
alkaloid
pharmaceutical formulations
formulations containing
alkaloid derivatives
salts
Prior art date
Application number
AT93304246T
Other languages
English (en)
Inventor
Ezio Bombardelli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of ATE192748T1 publication Critical patent/ATE192748T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/16Esters of thiophosphoric acids or thiophosphorous acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D461/00Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • C07F9/106Adducts, complexes, salts of phosphatides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07GCOMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G5/00Alkaloids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
AT93304246T 1992-06-02 1993-06-01 Neue alkaloidderivate, ihre verwendung und diese enthaltende pharmazeutische formulierungen ATE192748T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929211659A GB9211659D0 (en) 1992-06-02 1992-06-02 New alkaloid derivatives,their use and pharmaceutical formulations containing them

Publications (1)

Publication Number Publication Date
ATE192748T1 true ATE192748T1 (de) 2000-05-15

Family

ID=10716398

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93304246T ATE192748T1 (de) 1992-06-02 1993-06-01 Neue alkaloidderivate, ihre verwendung und diese enthaltende pharmazeutische formulierungen

Country Status (11)

Country Link
US (1) US5334385A (de)
EP (1) EP0573260B1 (de)
JP (1) JPH06321971A (de)
KR (1) KR100263085B1 (de)
AT (1) ATE192748T1 (de)
DE (1) DE69328585T2 (de)
DK (1) DK0573260T3 (de)
ES (1) ES2145029T3 (de)
GB (1) GB9211659D0 (de)
GR (1) GR3033394T3 (de)
PT (1) PT573260E (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1269634B (it) * 1994-05-06 1997-04-08 Indena Spa Medicamento topico ad attivita' cicatrizzante
ITMI20080284A1 (it) * 2008-02-22 2009-08-23 Indena Spa Agenti antitumorali a struttura benzofenantridinica e formulazioni che li contengono

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2935448A (en) * 1959-02-25 1960-05-03 Royall M Calder Phosphatide therapeutic composition and method of treatment therewith
US4254115A (en) * 1979-06-18 1981-03-03 A. Nattermann & Cie. Gmbh Phospholipid derivative with an antilipemic and antiarteriosclerotic effect
DE3170312D1 (en) * 1980-10-07 1985-06-05 Klaus Keplinger Extract from uncaria tomentosa (willd.) dc. for use in therapy
US4818533A (en) * 1985-07-09 1989-04-04 Vipont Pharmaceutical, Inc. Production of high purity alkaloids
IT1215291B (it) * 1985-07-17 1990-01-31 Inverni Della Beffa Spa Complessi di flavanolignani con fosfolipidi, loro preparazione e relative composizioni farmaceutiche.
DE3613799C1 (de) * 1986-04-24 1987-09-03 Nattermann A & Cie Verwendung von Glycofurol zum Verfluessigen von Arzneimittelzubereitungen fuer das Abfuellen in Weichgelatinekapseln
IT1201149B (it) * 1987-01-14 1989-01-27 Indena Spa Complessi di bioflavonoidi con fosfolipidi,loro preparazione,uso e composizioni farmaceutici e cosmetiche
US4830028A (en) * 1987-02-10 1989-05-16 R. J. Reynolds Tobacco Company Salts provided from nicotine and organic acid as cigarette additives
US5009819A (en) * 1987-11-12 1991-04-23 The Liposome Company, Inc. Taste moderating composition
US4952408A (en) * 1988-05-23 1990-08-28 Georgetown University Liposome-encapsulated vinca alkaloids and their use in combatting tumors

Also Published As

Publication number Publication date
DE69328585D1 (de) 2000-06-15
EP0573260B1 (de) 2000-05-10
PT573260E (pt) 2000-10-31
EP0573260A1 (de) 1993-12-08
ES2145029T3 (es) 2000-07-01
DE69328585T2 (de) 2001-01-04
DK0573260T3 (da) 2000-09-25
GB9211659D0 (en) 1992-07-15
US5334385A (en) 1994-08-02
HK1003942A1 (en) 1998-11-13
JPH06321971A (ja) 1994-11-22
KR100263085B1 (ko) 2000-08-01
KR940000462A (ko) 1994-01-03
GR3033394T3 (en) 2000-09-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee