ATE195529T1 - 17beta-(2-oxo-tetrahydrofuran-4-yl)-thio- androstane derivate (17beta-(gamma-buttersäure- lacton)-thio derivate) zur behandlung von entzündungen, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung - Google Patents

17beta-(2-oxo-tetrahydrofuran-4-yl)-thio- androstane derivate (17beta-(gamma-buttersäure- lacton)-thio derivate) zur behandlung von entzündungen, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung

Info

Publication number: ATE195529T1
Authority: AT; Austria
Prior art keywords: 17beta; thio; derivatives; lactone; oxo
Prior art date: 1995-12-29

Application number

AT96942491T

Other languages

English (en)

Inventor

Keith Biggadike

Panayiotis Alexandro Procopiou

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-29

Filing date

1996-12-19

Publication date

2000-09-15

1995-12-29 Priority claimed from GBGB9526677.1A external-priority patent/GB9526677D0/en

1996-06-21 Priority claimed from GBGB9613120.6A external-priority patent/GB9613120D0/en

1996-12-19 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2000-09-15 Application granted granted Critical

2000-09-15 Publication of ATE195529T1 publication Critical patent/ATE195529T1/de

Links

206010061218 Inflammation Diseases 0.000 title 1
230000004054 inflammatory process Effects 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
239000012453 solvate Substances 0.000 abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
150000001441 androstanes Chemical class 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
239000000043 antiallergic agent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT96942491T 1995-12-29 1996-12-19 17beta-(2-oxo-tetrahydrofuran-4-yl)-thio- androstane derivate (17beta-(gamma-buttersäure- lacton)-thio derivate) zur behandlung von entzündungen, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung ATE195529T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9526677.1A GB9526677D0 (en)	1995-12-29	1995-12-29	Compounds
GBGB9613120.6A GB9613120D0 (en)	1996-06-21	1996-06-21	Compounds
PCT/GB1996/003138 WO1997024368A1 (en)	1995-12-29	1996-12-19	17beta-(2-oxo-tetrahydrofuran-4-yl)-thio-androstane derivatives (17beta-(gamma-butyric acid lactone)-thio derivatives) for the treatment of inflammation and pharmaceutical compositions and a process for the production thereof

Publications (1)

Publication Number	Publication Date
ATE195529T1 true ATE195529T1 (de)	2000-09-15

Family

ID=26308405

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96942491T ATE195529T1 (de)	1995-12-29	1996-12-19	17beta-(2-oxo-tetrahydrofuran-4-yl)-thio- androstane derivate (17beta-(gamma-buttersäure- lacton)-thio derivate) zur behandlung von entzündungen, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung

Country Status (11)

Country	Link
US (1)	US6114318A (de)
EP (1)	EP0883628B1 (de)
JP (1)	JP2951000B2 (de)
AT (1)	ATE195529T1 (de)
AU (1)	AU1185197A (de)
DE (1)	DE69609870T2 (de)
DK (1)	DK0883628T3 (de)
ES (1)	ES2150149T3 (de)
GR (1)	GR3034439T3 (de)
PT (1)	PT883628E (de)
WO (1)	WO1997024368A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU8439998A (en) *	1997-06-30	1999-01-25	Glaxo Group Limited	Compounds
JP3847065B2 (ja) *	2000-08-21	2006-11-15	松下電器産業株式会社	地点登録装置
ITRM20020458A1 (it) *	2002-09-13	2004-03-14	Ambiotec S A S Di Ammendola Sergio	Procedimento per la separazione preparativa degli epimeri di steroidi.
CA2764830A1 (en)	2009-06-16	2010-12-23	Schering Corporation	Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4481144A (en) *	1984-02-03	1984-11-06	E. R. Squibb & Sons, Inc.	17-Substituted thia-17-alkyl(or alkenyl or alkynyl)androstenes
US4529548A (en) *	1984-05-07	1985-07-16	E. R. Squibb & Sons, Inc.	17β-(substituted thio)androstenes
CA2149777C (en) *	1992-12-24	2004-05-25	Michael John Ashton	New steroids

1996
- 1996-12-19 ES ES96942491T patent/ES2150149T3/es not_active Expired - Lifetime
- 1996-12-19 US US09/091,747 patent/US6114318A/en not_active Expired - Fee Related
- 1996-12-19 AT AT96942491T patent/ATE195529T1/de not_active IP Right Cessation
- 1996-12-19 AU AU11851/97A patent/AU1185197A/en not_active Abandoned
- 1996-12-19 WO PCT/GB1996/003138 patent/WO1997024368A1/en not_active Ceased
- 1996-12-19 PT PT96942491T patent/PT883628E/pt unknown
- 1996-12-19 EP EP96942491A patent/EP0883628B1/de not_active Expired - Lifetime
- 1996-12-19 DE DE69609870T patent/DE69609870T2/de not_active Expired - Fee Related
- 1996-12-19 JP JP9524094A patent/JP2951000B2/ja not_active Expired - Fee Related
- 1996-12-19 DK DK96942491T patent/DK0883628T3/da active
2000
- 2000-09-20 GR GR20000402131T patent/GR3034439T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO1997024368A1 (en)	1997-07-10
ES2150149T3 (es)	2000-11-16
DE69609870T2 (de)	2001-01-25
DK0883628T3 (da)	2000-11-06
GR3034439T3 (en)	2000-12-29
AU1185197A (en)	1997-07-28
DE69609870D1 (de)	2000-09-21
JP2951000B2 (ja)	1999-09-20
PT883628E (pt)	2001-01-31
EP0883628B1 (de)	2000-08-16
EP0883628A1 (de)	1998-12-16
JPH11501674A (ja)	1999-02-09
US6114318A (en)	2000-09-05

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Legal Events

Date	Code	Title	Description
2001-02-15	UEP	Publication of translation of european patent specification
2005-09-15	REN	Ceased due to non-payment of the annual fee