ATE196147T1 - Wachstumsdifferenzierungsfaktor-12 - Google Patents

Wachstumsdifferenzierungsfaktor-12

Info

Publication number
ATE196147T1
ATE196147T1 AT95928062T AT95928062T ATE196147T1 AT E196147 T1 ATE196147 T1 AT E196147T1 AT 95928062 T AT95928062 T AT 95928062T AT 95928062 T AT95928062 T AT 95928062T AT E196147 T1 ATE196147 T1 AT E196147T1
Authority
AT
Austria
Prior art keywords
pct
differentiation factor
growth differentiation
gdf
sec
Prior art date
Application number
AT95928062T
Other languages
English (en)
Inventor
Se-Jin Lee
Aurora F Esquela
Original Assignee
Univ Johns Hopkins Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/274,215 external-priority patent/US5831054A/en
Application filed by Univ Johns Hopkins Med filed Critical Univ Johns Hopkins Med
Application granted granted Critical
Publication of ATE196147T1 publication Critical patent/ATE196147T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT95928062T 1994-07-13 1995-07-12 Wachstumsdifferenzierungsfaktor-12 ATE196147T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/274,215 US5831054A (en) 1994-07-13 1994-07-13 Polynucleotide encoding growth differentiation factor-12
US31137094A 1994-09-26 1994-09-26
PCT/US1995/008745 WO1996002559A1 (en) 1994-07-13 1995-07-12 Growth differentiation factor-12

Publications (1)

Publication Number Publication Date
ATE196147T1 true ATE196147T1 (de) 2000-09-15

Family

ID=26956672

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95928062T ATE196147T1 (de) 1994-07-13 1995-07-12 Wachstumsdifferenzierungsfaktor-12

Country Status (11)

Country Link
US (1) US5929213A (de)
EP (1) EP0770089B1 (de)
JP (1) JPH10503362A (de)
AT (1) ATE196147T1 (de)
CA (1) CA2195246A1 (de)
DE (1) DE69518760T2 (de)
DK (1) DK0770089T3 (de)
ES (1) ES2151607T3 (de)
GR (1) GR3034772T3 (de)
PT (1) PT770089E (de)
WO (1) WO1996002559A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
AU689184B2 (en) 1993-12-07 1998-03-26 Genetics Institute, Llc BMP-12, BMP-13 and tendon-inducing compositions thereof
US5846770A (en) * 1994-11-22 1998-12-08 Genetics Institute, Inc. DNA molecules encoding human chordin
US5965403A (en) * 1996-09-18 1999-10-12 Genetics Institute, Inc. Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
US20020052026A1 (en) 1997-10-08 2002-05-02 Steven M. Vicik Methods of refolding proteins
US6027917A (en) 1997-12-10 2000-02-22 Genetics Institute, Inc. Bone morphogenetic protein (BMP)-17 and BMP-18 compositions
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
EP2286847A1 (de) 1999-10-15 2011-02-23 Genetics Institute, LLC Hyaluronsäure enthaltende Zusammensetzungen zur Abgabe osteogener Proteine
DE60026592T2 (de) * 1999-12-15 2006-12-14 Research Development Foundation, Carson City Betaglycan als ein inhibin rezeptor und dessen verwendung
US7226587B2 (en) 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
ES2282904T3 (es) 2003-09-12 2007-10-16 Wyeth Barras solidas de fosfato calcico inyectables para el suministro de proteinas osteogenicas.
EP1740609A2 (de) 2004-04-27 2007-01-10 Research Development Foundation Antagonismus des tgf-beta superfamily signal rezeptors
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US8147860B2 (en) 2005-12-06 2012-04-03 Etex Corporation Porous calcium phosphate bone material
ES2427993T3 (es) 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
US9642891B2 (en) 2006-06-30 2017-05-09 Biomimetic Therapeutics, Llc Compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
US8524265B2 (en) 2006-08-17 2013-09-03 Warsaw Orthopedic, Inc. Medical implant sheets useful for tissue regeneration
MX2011002555A (es) 2008-09-09 2011-08-03 Biomimetic Therapeutics Inc Composiciones de factor de crecimiento derivadas de plaquetas y metodo para el tratamiento de lesiones de tendon y ligamentos.
US8609127B2 (en) 2009-04-03 2013-12-17 Warsaw Orthopedic, Inc. Medical implant with bioactive material and method of making the medical implant
WO2010144696A1 (en) 2009-06-11 2010-12-16 Burnham Institute For Medical Research Directed differentiation of stem cells
WO2011103598A1 (en) 2010-02-22 2011-08-25 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of tendinopathies
WO2014012101A1 (en) 2012-07-13 2014-01-16 Trustees Of Tufts College Silk powder compaction for production of constructs with high mechanical strength and stiffness
EP3821880A1 (de) 2015-10-26 2021-05-19 President and Fellows of Harvard College Oxidierte polysaccharide und verfahren zur verwendung davon

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ287715B6 (en) * 1992-02-12 2001-01-17 Bioph Biotech Entw Pharm Gmbh DNA sequence, recombinant DNA molecule containing thereof, process for preparing protein from the group of TGF-beta substances, pharmaceutical preparation containing such protein, antibody or fragment thereof and its use

Also Published As

Publication number Publication date
PT770089E (pt) 2001-02-28
JPH10503362A (ja) 1998-03-31
WO1996002559A1 (en) 1996-02-01
EP0770089A4 (de) 1997-06-18
ES2151607T3 (es) 2001-01-01
DE69518760T2 (de) 2001-05-23
DE69518760D1 (de) 2000-10-12
GR3034772T3 (en) 2001-02-28
EP0770089B1 (de) 2000-09-06
EP0770089A1 (de) 1997-05-02
CA2195246A1 (en) 1996-02-01
US5929213A (en) 1999-07-27
DK0770089T3 (da) 2000-10-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee