ATE196508T1 - Enantiomere von cyclopenten-derivaten - Google Patents
Enantiomere von cyclopenten-derivatenInfo
- Publication number
- ATE196508T1 ATE196508T1 AT92908235T AT92908235T ATE196508T1 AT E196508 T1 ATE196508 T1 AT E196508T1 AT 92908235 T AT92908235 T AT 92908235T AT 92908235 T AT92908235 T AT 92908235T AT E196508 T1 ATE196508 T1 AT E196508T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- image
- enantiomers
- iia
- cyclopent
- Prior art date
Links
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical compound C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title abstract 3
- LMKPHJYTFHAGHK-UHFFFAOYSA-N cyclodrine Chemical class C1CCCC1(O)C(C(=O)OCCN(CC)CC)C1=CC=CC=C1 LMKPHJYTFHAGHK-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000036983 biotransformation Effects 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 239000002777 nucleoside Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic
- C07C35/06—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/874—Pseudomonas
- Y10S435/876—Pseudomonas fluorescens
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919108376A GB9108376D0 (en) | 1991-04-19 | 1991-04-19 | Cyclopentenes |
| PCT/GB1992/000730 WO1992018444A2 (en) | 1991-04-19 | 1992-04-21 | Cyclopentenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE196508T1 true ATE196508T1 (de) | 2000-10-15 |
Family
ID=10693560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92908235T ATE196508T1 (de) | 1991-04-19 | 1992-04-21 | Enantiomere von cyclopenten-derivaten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5714351A (de) |
| EP (1) | EP0580667B1 (de) |
| AT (1) | ATE196508T1 (de) |
| AU (1) | AU1548592A (de) |
| DE (1) | DE69231466T2 (de) |
| ES (1) | ES2150913T3 (de) |
| GB (1) | GB9108376D0 (de) |
| WO (1) | WO1992018444A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9108376D0 (en) * | 1991-04-19 | 1991-06-05 | Enzymatix Ltd | Cyclopentenes |
| US5840923A (en) * | 1992-04-21 | 1998-11-24 | Chiroscience Limited | Chiral cyclopentene derivatives and their preparation |
| CA2133959A1 (en) * | 1992-04-21 | 1993-10-28 | Chirotech Technology Limited | Chiral cyclopentene derivatives and their preparation |
| JPH07147994A (ja) * | 1993-11-26 | 1995-06-13 | Kureha Chem Ind Co Ltd | １，２−ジオール誘導体の光学分割 |
| WO2000039324A2 (de) * | 1998-12-23 | 2000-07-06 | Lonza Ag | Verfahren zur herstellung von optisch aktiven 1- amino-4- (hydroxymethyl)- cyclopent-2- en-derivaten |
| HK1042078B (zh) | 1999-01-06 | 2004-01-30 | Lonza Ag | 生产robenidine或其衍生物的方法 |
| ES2209710T3 (es) * | 1999-04-27 | 2004-07-01 | Firmenich Sa | Procedimiento de preparacion de epoxidos quirales. |
| US8236853B1 (en) | 2007-12-03 | 2012-08-07 | University Of South Florida | Formation of cyclopentene nitro-ester and derivatives |
| JP2009232735A (ja) * | 2008-03-26 | 2009-10-15 | Tadakatsu Bandai | （１ｒ，２ｒ）−１−アシロキシ−３−シクロアルケン又は（１ｓ，２ｓ）−３−シクロアルケン−１−オールの製造方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3965118A (en) * | 1972-07-21 | 1976-06-22 | The Upjohn Company | Lactone intermediates |
| US4217284A (en) * | 1976-10-05 | 1980-08-12 | Kowa Company Ltd. | Process for preparation of optically pure lactones from monoesters of cis-cyclopentenediol |
| GB1561314A (en) * | 1976-10-05 | 1980-02-20 | Kowa Co | Monoesters of cis - cyclopentenedio process for preparation thereof and process for preparation of lactones from the monoesters |
| DE3474546D1 (en) * | 1983-02-03 | 1988-11-17 | Sumitomo Chemical Co | Optically active 4-hydroxy-2-cyclopentenones, and their production |
| EP0149674B1 (de) * | 1983-03-18 | 1988-08-10 | Sumitomo Chemical Company, Limited | Verfahren zur optisch-biochemischen auflösung eines cyclopentenolonabkömmlings |
| DE3465185D1 (en) * | 1983-05-25 | 1987-09-10 | Sumitomo Chemical Co | Process for producing optically active cyclopentenolones |
| DE3439598A1 (de) * | 1984-06-01 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von (1s, 4r)-4-hydroxy-2-cyclopentenylestern |
| ES2001094A6 (es) * | 1985-08-16 | 1988-04-16 | Glaxo Group Ltd | Un procedimiento para la preparacion de un derivado de guanina |
| DE3638762A1 (de) * | 1986-11-13 | 1988-05-26 | Schering Ag | Racematspaltung von 7(alpha)-acyloxy-6ss-hydroxy-methyl-2-oxabicyclo (3.3.0)octan-3-onen durch stereospezifische enzymatische acylat-hydrolyse |
| EP0267878A1 (de) * | 1986-11-14 | 1988-05-18 | Ciba-Geigy Ag | N9-Cyclopentylsubstituierte Adeninderivate |
| DE3724721A1 (de) * | 1987-07-25 | 1989-04-13 | Hoechst Ag | Verfahren zur enzymatischen racematspaltung von 1-acyloxy-2-cyclopenten-4-on(2,2- dimethylpropandiol)-ketal |
| DE3743824C2 (de) * | 1987-12-23 | 1997-03-06 | Hoechst Ag | Verfahren zur enzymatischen Racematspaltung von racemischen Alkoholen mit/in Vinylestern durch Umesterung |
| US4916224A (en) * | 1988-01-20 | 1990-04-10 | Regents Of The University Of Minnesota | Dideoxycarbocyclic nucleosides |
| US4950758A (en) * | 1988-01-20 | 1990-08-21 | Regents Of The University Of Minnesota | Optically-active isomers of dideoxycarbocyclic nucleosides |
| CH679152A5 (de) * | 1988-01-20 | 1991-12-31 | Univ Minnesota | |
| LU87593A1 (de) * | 1989-09-25 | 1991-05-07 | Europ Communities | Enantioselektive enzymatische synthese von s(-)-und r(+)-estern des 4-hydroxy-cyclopenten-1-ons und seines 2',2'-dimethylpropan-1',3'-diol-ketals |
| MY104575A (en) * | 1989-12-22 | 1994-04-30 | The Wellcome Foundation Ltd | Therapeutic nucleosides. |
| US5057630A (en) * | 1990-04-06 | 1991-10-15 | Glaxo Inc. | Synthesis of cyclopentene derivatives |
| JP3097145B2 (ja) * | 1991-02-27 | 2000-10-10 | 日産化学工業株式会社 | コーリーラクトンジオールの光学分割方法 |
| GB9108376D0 (en) * | 1991-04-19 | 1991-06-05 | Enzymatix Ltd | Cyclopentenes |
-
1991
- 1991-04-19 GB GB919108376A patent/GB9108376D0/en active Pending
-
1992
- 1992-04-21 WO PCT/GB1992/000730 patent/WO1992018444A2/en not_active Ceased
- 1992-04-21 AU AU15485/92A patent/AU1548592A/en not_active Abandoned
- 1992-04-21 EP EP92908235A patent/EP0580667B1/de not_active Expired - Lifetime
- 1992-04-21 DE DE69231466T patent/DE69231466T2/de not_active Expired - Fee Related
- 1992-04-21 ES ES92908235T patent/ES2150913T3/es not_active Expired - Lifetime
- 1992-04-21 AT AT92908235T patent/ATE196508T1/de not_active IP Right Cessation
- 1992-04-21 US US08/211,623 patent/US5714351A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB9108376D0 (en) | 1991-06-05 |
| EP0580667B1 (de) | 2000-09-20 |
| US5714351A (en) | 1998-02-03 |
| WO1992018444A3 (en) | 1993-03-04 |
| AU1548592A (en) | 1992-11-17 |
| ES2150913T3 (es) | 2000-12-16 |
| EP0580667A1 (de) | 1994-02-02 |
| WO1992018444A2 (en) | 1992-10-29 |
| DE69231466D1 (de) | 2000-10-26 |
| DE69231466T2 (de) | 2001-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |