ATE196763T1 - Zusammenstellungen, um den haarausfall zu hemmen und um haarwuchs zu induzieren und zu stimulieren auf basis von 2,4-diamino-pyrimidin-3- oxydderivaten - Google Patents

Zusammenstellungen, um den haarausfall zu hemmen und um haarwuchs zu induzieren und zu stimulieren auf basis von 2,4-diamino-pyrimidin-3- oxydderivaten

Info

Publication number
ATE196763T1
ATE196763T1 AT92401980T AT92401980T ATE196763T1 AT E196763 T1 ATE196763 T1 AT E196763T1 AT 92401980 T AT92401980 T AT 92401980T AT 92401980 T AT92401980 T AT 92401980T AT E196763 T1 ATE196763 T1 AT E196763T1
Authority
AT
Austria
Prior art keywords
denotes
oxyde
diamino
pyrimidine
induce
Prior art date
Application number
AT92401980T
Other languages
English (en)
Inventor
Eric Terranova
Jean-Baptiste Galey
Michel Hocquaux
Jean Maignan
Remy Tuloup
Original Assignee
Oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oreal filed Critical Oreal
Application granted granted Critical
Publication of ATE196763T1 publication Critical patent/ATE196763T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/01—Aerosol hair preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT92401980T 1991-07-11 1992-07-09 Zusammenstellungen, um den haarausfall zu hemmen und um haarwuchs zu induzieren und zu stimulieren auf basis von 2,4-diamino-pyrimidin-3- oxydderivaten ATE196763T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9108764A FR2678929A1 (fr) 1991-07-11 1991-07-11 Compositions pour freiner la chute des cheveux et pour induire et stimuler leur croissance a base de derives de 2,4-diamino pyrimidine 3-oxyde, nouveaux derives 2,4-diamino pyrimidine 3-oxyde.

Publications (1)

Publication Number Publication Date
ATE196763T1 true ATE196763T1 (de) 2000-10-15

Family

ID=9415004

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92401980T ATE196763T1 (de) 1991-07-11 1992-07-09 Zusammenstellungen, um den haarausfall zu hemmen und um haarwuchs zu induzieren und zu stimulieren auf basis von 2,4-diamino-pyrimidin-3- oxydderivaten

Country Status (8)

Country Link
US (1) US5466694A (de)
EP (1) EP0522964B1 (de)
JP (1) JPH05194230A (de)
AT (1) ATE196763T1 (de)
CA (1) CA2073755A1 (de)
DE (1) DE69231488T2 (de)
ES (1) ES2150911T3 (de)
FR (1) FR2678929A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679378A (en) * 1995-12-18 1997-10-21 Olim Industries Of Israel, North America, Ltd. Method and material for hair therapy
FR2781481B1 (fr) 1998-07-24 2000-09-15 Oreal Nouveaux 2-amino, 4-alkylamino pyrimidine 3-oxydes et composition les comprenant
DE19845202A1 (de) * 1998-10-01 2000-04-06 Wella Ag Haarwuchsmittel
US6159950A (en) * 1998-10-16 2000-12-12 Cornell Research Foundation, Inc. Method of modulating hair growth
FR2785802B1 (fr) * 1998-11-12 2002-10-31 Oreal 2-amino, 4-alkylamino pyrimidine 3-oxydes comme anti-inflammatoires
FR2791671B1 (fr) 1999-04-01 2001-05-11 Oreal Nouveaux composes derives d'esters d'acide benzoique, composition les comprenant et utilisation
EP2260845A3 (de) 2002-06-21 2012-08-22 L'Oréal Verwendung von Polyphenolen zur Behandlung der Alopezie
US7326717B2 (en) 2003-05-06 2008-02-05 L'oreal Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof
FR2854630B1 (fr) * 2003-05-06 2005-06-10 Oreal Composition capilaire contenant un derive de pyrimidine n-oxydase, son utilisation pour stimuler la pousse des fibres keratiniques et/ou freiner leur chute
EP1653975A4 (de) * 2003-07-31 2006-10-25 Univ Texas Zusammensetzungen und verfahren zur behandlung, prävention und/oder linderung von krebs, dem einsetzen von krebs oder der symptome von krebs
US20060193804A1 (en) * 2005-02-24 2006-08-31 L'oreal Haircare use of cyclic amine derivatives
FR2920309B1 (fr) 2007-08-28 2010-05-28 Galderma Res & Dev Utilisation de travoprost pour traiter la chute des cheveux
FR2949052B1 (fr) 2009-08-13 2015-03-27 Oreal Procede de traitement cosmetique du cuir chevelu.
FR2953722B1 (fr) 2009-12-16 2012-03-09 Expanscience Lab Composition comprenant au moins un sucre en c7 pour le traitement de l'alopecie, pour le traitement cosmetique des phaneres, et pour le soin des cheveux, cils ou ongles
CA2870666A1 (en) 2012-04-16 2013-10-24 Case Western Reserve University Compositions and methods of modulating 15-pgdh activity
CA2927730A1 (en) 2013-10-15 2015-05-07 Case Western Reserve University Compositions and methods of modulating short-chain dehydrogenase activity
WO2015085373A1 (en) 2013-12-12 2015-06-18 Cellmid Limited Method of treatment of alopecia with monoterpenoids
EP3226859B1 (de) 2014-12-05 2025-03-26 Case Western Reserve University Akr1a1-inhibitoren zur verwendung zur senkung des cholesterinspiegels und zur modulation der s-nitrosylierung
EP3548035A4 (de) 2016-11-30 2020-07-22 Case Western Reserve University Kombinationen von 15-pgdh-inhibitoren mit corticosteroiden und/oder tnf-inhibitoren und verwendungen davon
CN110573154A (zh) 2017-02-06 2019-12-13 卡斯西部储备大学 调节短链脱氢酶活性的组合物和方法
WO2020106998A1 (en) 2018-11-21 2020-05-28 Case Western Reserve University Compositions and methods of modulating short-chain dehydrogenase activity
FR3089413B1 (fr) 2018-12-06 2021-02-19 Fabre Pierre Dermo Cosmetique Extrait de Garcinia mangostana pour promouvoir la croissance capillaire
FR3099699B1 (fr) 2019-08-06 2025-09-26 Fabre Pierre Dermo Cosmetique Extrait d’akènes de Silybum marianum (L.) Gaertn. pour promouvoir la croissance capillaire
AU2021224268A1 (en) 2020-02-21 2022-09-15 Case Western Reserve University Compositions and methods for treating renal injury
EP3895685A1 (de) 2020-04-14 2021-10-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Natürliche zusammensetzung zur haarwachstumsstimulation und haarverlustverhinderung und behandlung ohne konservierungsmittel
EP3895686B1 (de) 2020-04-14 2025-04-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Natürliche zusammensetzung zur stimulierung des haarwuchses und zur vorbeugung und behandlung von haarausfall
CR20220654A (es) 2020-05-20 2023-08-24 Rodeo Therapeutics Corp Composiciones y métodos para modular la actividad de deshidrogenasas de cadena corta
CN116789606B (zh) * 2023-06-20 2025-12-09 上药康丽（常州）药业有限公司 2,4－二氨基-5,6－二氯嘧啶的合成与精制方法
FR3156660A1 (fr) 2023-12-13 2025-06-20 Pierre Fabre Dermo-Cosmetique Extrait de Verbena officinalis pour la prévention et/ou le traitement de la chute des cheveux

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3382248A (en) * 1965-11-01 1968-05-07 Upjohn Co 6-amino-4, 5-di(substituted amino)-1, 2-dihydro-1-hydroxy-2-iminopyrimidines
US3637697A (en) * 1965-11-01 1972-01-25 Upjohn Co 6-amino-1 2-dihydro-1-hydroxy-2-iminopyrimidines
US4139619A (en) * 1976-05-24 1979-02-13 The Upjohn Company 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth
LU86548A1 (fr) * 1986-08-07 1988-03-02 Oreal Composition sous forme de gel pour induire et stimuler la croissance des cheveux et diminuer leur chute a base de derives de piperidino-pyrimidine
LU87308A1 (fr) * 1988-08-01 1990-03-13 Oreal Nouveaux derives de diamino-2,4 pyrimidine oxyde-3 et leur utilisation pour le traitement et la prevention de la chute des cheveux
ATE110718T1 (de) * 1989-07-12 1994-09-15 Oreal Halogenierte pyrimidin-3-oxid-derivate, deren verwendung für die behandlung und die verhütung von haarausfall und für die wachstumsförderung von haaren.

Also Published As

Publication number Publication date
EP0522964B1 (de) 2000-10-04
EP0522964A1 (de) 1993-01-13
ES2150911T3 (es) 2000-12-16
US5466694A (en) 1995-11-14
DE69231488T2 (de) 2001-02-08
JPH05194230A (ja) 1993-08-03
FR2678929B1 (de) 1995-02-24
DE69231488D1 (de) 2000-11-09
FR2678929A1 (fr) 1993-01-15
CA2073755A1 (fr) 1993-01-12

Similar Documents

Publication Publication Date Title
DE69231488D1 (de) Zusammenstellungen, um den Haarausfall zu hemmen und um Haarwuchs zu induzieren und zu stimulieren auf Basis von 2,4-Diamino-pyrimidin-3-Oxydderivaten
SE8504291L (sv) Aromatiska heterocykliska derivat och deras anvendning inom det terapeutiska och kosmetiska omradet
FR2651122B1 (fr) Compositions destinees a etre utilisees pour freiner la chute des cheveux et pour induire et stimuler leur croissance, contenant des derives de l'amino-2 pyrimidine oxyde-3 et nouveaux composes derives de l'amino-2 pyrimidine oxyde-3.
ES2075648T3 (es) Composicion para frenar la caida de los cabellos, y para inducir y estimular su crecimiento, a base de derivados de pirimidinas-n-oxido trisustituidas en las posiciones 2, 4 y 6 por una funcion amina, y nuevos compuestos de pirimidina-n-oxido.
DK0756595T3 (da) Substituerede 1,3-oxathiolaner med antivirale egenskaber
DK114088A (da) 5-alkoxy-2,4-diamino-alkylbenzener samt haarfarvningsmiddel med 5-alkoxy-2,4-diamino-alkyl-benzener
ES2147223T3 (es) Derivados de indol como agonistas de tipo 5-ht1.
JPS568361A (en) Pyroglutamic acid derivative and analogue
ATE134366T1 (de) Amid derivate von vitamin d
ES8802152A1 (es) Procedimiento para preparar un derivado de 1,3-oxazolidina-2-ona.
MY113427A (en) Anti-neurodegeneratively active 10-aminoaliphatyl- dibenz [b,f] oxepines
IL66835A0 (en) Triazoloquinazolone derivatives and their salts,their preparation,their use as medicaments and the compositions containing them
DK415789D0 (da) Tetracykliske antidepressive midler
GR3030234T3 (en) 4-Phenylcarbamoyl-3-isoxazolecarboxylic acid derivatives with antiinflammatory activity
DE3062614D1 (en) Derivatives of tetrahydropyridinyl-indol and their salts, their preparation, their application as medicines, and compositions containing them
DE68921719D1 (de) Amphotericin B Derivate.
SE8703068L (sv) Komposition for att inducera och stimulera hartillvext och minska haravfall baserad pa pyrimidinderivat
GR78774B (de)
DK96086A (da) 8-thiotetrahydroquinolinderivater, deres fremstilling og anvendelse som laegemidler
ATE144900T1 (de) Verwendung von xanthinderivaten gegen magengeschwüre
ATE19629T1 (de) N-substituierte derivate des tetrahydroisophthalimids.
ES8604512A1 (es) Procedimiento para la obtencion de fenilhidrazonpirrolidinas substituidas

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee