ATE197058T1 - Matrizen auf basis von kollagen und synthetischem polymer hergestellt unter verwendung einer mehrstufigen reaktion - Google Patents
Matrizen auf basis von kollagen und synthetischem polymer hergestellt unter verwendung einer mehrstufigen reaktionInfo
- Publication number
- ATE197058T1 ATE197058T1 AT95103895T AT95103895T ATE197058T1 AT E197058 T1 ATE197058 T1 AT E197058T1 AT 95103895 T AT95103895 T AT 95103895T AT 95103895 T AT95103895 T AT 95103895T AT E197058 T1 ATE197058 T1 AT E197058T1
- Authority
- AT
- Austria
- Prior art keywords
- matrix
- collagen
- synthetic polymer
- synthetic
- activated
- Prior art date
Links
- 229920001059 synthetic polymer Polymers 0.000 title abstract 8
- 102000008186 Collagen Human genes 0.000 title abstract 4
- 108010035532 Collagen Proteins 0.000 title abstract 4
- 229920001436 collagen Polymers 0.000 title abstract 4
- 238000003541 multi-stage reaction Methods 0.000 title 1
- 239000011159 matrix material Substances 0.000 abstract 10
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 3
- 229920002683 Glycosaminoglycan Polymers 0.000 abstract 2
- 238000004132 cross linking Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000010382 chemical cross-linking Methods 0.000 abstract 1
- 230000001268 conjugating effect Effects 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 239000003431 cross linking reagent Substances 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
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- C08L2666/00—Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
- C08L2666/02—Organic macromolecular compounds, natural resins, waxes or and bituminous materials
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
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- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
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- Materials Engineering (AREA)
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- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/236,769 US5475052A (en) | 1988-11-21 | 1994-05-02 | Collagen-synthetic polymer matrices prepared using a multiple step reaction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE197058T1 true ATE197058T1 (de) | 2000-11-15 |
Family
ID=22890882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95103895T ATE197058T1 (de) | 1994-05-02 | 1995-03-16 | Matrizen auf basis von kollagen und synthetischem polymer hergestellt unter verwendung einer mehrstufigen reaktion |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5475052A (de) |
| EP (1) | EP0680990B1 (de) |
| JP (4) | JPH0853548A (de) |
| AT (1) | ATE197058T1 (de) |
| AU (1) | AU698233B2 (de) |
| CA (1) | CA2143923A1 (de) |
| DE (1) | DE69519124T2 (de) |
Families Citing this family (136)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5614587A (en) * | 1988-11-21 | 1997-03-25 | Collagen Corporation | Collagen-based bioadhesive compositions |
| US5936035A (en) * | 1988-11-21 | 1999-08-10 | Cohesion Technologies, Inc. | Biocompatible adhesive compositions |
| US5475052A (en) * | 1988-11-21 | 1995-12-12 | Collagen Corporation | Collagen-synthetic polymer matrices prepared using a multiple step reaction |
| US5843089A (en) | 1990-12-28 | 1998-12-01 | Boston Scientific Corporation | Stent lining |
| USRE38827E1 (en) | 1994-07-27 | 2005-10-11 | 3M Innovative Properties Company | Adhesive sealant composition |
| US5583114A (en) | 1994-07-27 | 1996-12-10 | Minnesota Mining And Manufacturing Company | Adhesive sealant composition |
| EP0713707A1 (de) * | 1994-11-23 | 1996-05-29 | Collagen Corporation | Injizierbare, in Situ vernetzbare Kollagenszusammensetzung für die Weichgewebevermehrung |
| DE19514087A1 (de) * | 1995-04-13 | 1996-10-17 | Deutsches Krebsforsch | Konjugat aus einem Wirkstoff, einem Polyether und ggfs. einem nicht als körperfremd angesehenen, nativen Protein |
| BR9609393A (pt) * | 1995-06-07 | 1999-12-21 | Organogenesis Inc | Composição injetável de colágeno; segmentos de fibra de colágeno reconstituìdos. |
| DK2111876T3 (da) | 1995-12-18 | 2011-12-12 | Angiodevice Internat Gmbh | Tværbundne polymerpræparater og fremgangsmåder til anvendelse deraf |
| US7883693B2 (en) | 1995-12-18 | 2011-02-08 | Angiodevice International Gmbh | Compositions and systems for forming crosslinked biomaterials and methods of preparation of use |
| US6458889B1 (en) | 1995-12-18 | 2002-10-01 | Cohesion Technologies, Inc. | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use |
| US5752974A (en) * | 1995-12-18 | 1998-05-19 | Collagen Corporation | Injectable or implantable biomaterials for filling or blocking lumens and voids of the body |
| US6833408B2 (en) | 1995-12-18 | 2004-12-21 | Cohesion Technologies, Inc. | Methods for tissue repair using adhesive materials |
| IL118848A0 (en) * | 1996-07-14 | 1996-10-31 | Univ Bar Ilan | Method for preparing bioactive polymers |
| US8003705B2 (en) | 1996-09-23 | 2011-08-23 | Incept Llc | Biocompatible hydrogels made with small molecule precursors |
| WO1998012274A1 (en) * | 1996-09-23 | 1998-03-26 | Chandrashekar Pathak | Methods and devices for preparing protein concentrates |
| US6566406B1 (en) | 1998-12-04 | 2003-05-20 | Incept, Llc | Biocompatible crosslinked polymers |
| US5856308A (en) * | 1996-09-27 | 1999-01-05 | Haemacure Corporation | Artificial collagen |
| AU4981897A (en) | 1996-10-15 | 1998-05-11 | Navix, Inc. | Stabilized conjugates of uncomplexed subunits of multimeric proteins |
| US6083522A (en) * | 1997-01-09 | 2000-07-04 | Neucoll, Inc. | Devices for tissue repair and methods for preparation and use thereof |
| US6679918B1 (en) | 1997-02-13 | 2004-01-20 | Centerpulse Biologics Inc. | Implantable putty material |
| EP1019027A4 (de) * | 1997-02-13 | 2004-05-12 | Sulzer Biolog Inc | Implantierbares kollagenhaltiges kittmaterial |
| EP1844798A1 (de) * | 1997-02-13 | 2007-10-17 | Zimmer Orthobiologics, Inc. | Implantierbares Kittmaterial |
| US6117979A (en) * | 1997-08-18 | 2000-09-12 | Medtronic, Inc. | Process for making a bioprosthetic device and implants produced therefrom |
| US6166184A (en) * | 1997-08-18 | 2000-12-26 | Medtronic Inc. | Process for making a bioprosthetic device |
| US7637948B2 (en) | 1997-10-10 | 2009-12-29 | Senorx, Inc. | Tissue marking implant |
| US8668737B2 (en) | 1997-10-10 | 2014-03-11 | Senorx, Inc. | Tissue marking implant |
| US20040081704A1 (en) | 1998-02-13 | 2004-04-29 | Centerpulse Biologics Inc. | Implantable putty material |
| MXPA00010110A (es) * | 1998-04-17 | 2002-08-06 | Angiogenix Inc | Factores angiogenicos terapeuticos y metodos para su uso. |
| DE19831699C1 (de) * | 1998-07-15 | 2000-04-27 | Caremed Medical Produkte Ag | Implantathalter |
| US6514534B1 (en) | 1998-08-14 | 2003-02-04 | Incept Llc | Methods for forming regional tissue adherent barriers and drug delivery systems |
| US20090216118A1 (en) | 2007-07-26 | 2009-08-27 | Senorx, Inc. | Polysaccharide markers |
| US8361082B2 (en) | 1999-02-02 | 2013-01-29 | Senorx, Inc. | Marker delivery device with releasable plug |
| US9820824B2 (en) | 1999-02-02 | 2017-11-21 | Senorx, Inc. | Deployment of polysaccharide markers for treating a site within a patent |
| US7983734B2 (en) | 2003-05-23 | 2011-07-19 | Senorx, Inc. | Fibrous marker and intracorporeal delivery thereof |
| US6862470B2 (en) | 1999-02-02 | 2005-03-01 | Senorx, Inc. | Cavity-filling biopsy site markers |
| US8498693B2 (en) | 1999-02-02 | 2013-07-30 | Senorx, Inc. | Intracorporeal marker and marker delivery device |
| US7651505B2 (en) | 2002-06-17 | 2010-01-26 | Senorx, Inc. | Plugged tip delivery for marker placement |
| US6725083B1 (en) | 1999-02-02 | 2004-04-20 | Senorx, Inc. | Tissue site markers for in VIVO imaging |
| AU2984700A (en) * | 1999-02-12 | 2000-08-29 | Collagenesis, Inc. | Injectable collagen-based delivery system for bone morphogenic proteins |
| US6726712B1 (en) | 1999-05-14 | 2004-04-27 | Boston Scientific Scimed | Prosthesis deployment device with translucent distal end |
| EP1203784B1 (de) * | 1999-05-19 | 2008-12-10 | Nof Corporation | Polymer, in vivo abbaubares material und dessen verwendung |
| US6576246B1 (en) * | 1999-05-24 | 2003-06-10 | Seefar Technologies, Inc. | Degradable animal chewing article possessing enhanced safety, durability and mouth-feel |
| EP1185309B1 (de) | 1999-06-11 | 2006-10-04 | Cytyc Corporation | Flüssige gelformulierung zum detektieren von milchkanälen in der brust vor einer chirurgischen ablation des brustgewebes |
| US6575991B1 (en) | 1999-06-17 | 2003-06-10 | Inrad, Inc. | Apparatus for the percutaneous marking of a lesion |
| US6592794B1 (en) | 1999-09-28 | 2003-07-15 | Organogenesis Inc. | Process of making bioengineered collagen fibrils |
| US6689161B2 (en) | 2000-04-28 | 2004-02-10 | Baylor College Of Medicine | Decellularized vascular prostheses resistant to thrombus occlusion and immunologic rejection |
| JP2004508884A (ja) * | 2000-09-25 | 2004-03-25 | コヒージョン テクノロジーズ, インコーポレイテッド | 再吸収可能な吻合ステントおよびプラグ |
| AU2002239290A1 (en) | 2000-11-20 | 2002-06-03 | Senorx, Inc. | Tissue site markers for in vivo imaging |
| US6407169B1 (en) * | 2000-12-13 | 2002-06-18 | The University Of Waterloo | Method for synthesis of graft polymers |
| US20020114795A1 (en) | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
| JP4230135B2 (ja) * | 2001-08-21 | 2009-02-25 | 独立行政法人科学技術振興機構 | 多官能性架橋剤によって架橋したグリコサミノグリカン−コラーゲン複合体の製造法 |
| DE60238422D1 (de) | 2001-09-24 | 2011-01-05 | Boston Scient Ltd | Optimierte dosierung bei paclitaxelhaltigen stents |
| US7879107B2 (en) * | 2002-02-20 | 2011-02-01 | The Cleveland Clinic Foundation | Composition and method for inducing bone growth and healing |
| WO2003071986A2 (en) * | 2002-02-22 | 2003-09-04 | Control Delivery Systems, Inc. | Method for treating otic disorders |
| JP5070442B2 (ja) | 2002-02-28 | 2012-11-14 | 株式会社Phg | 新規なポリペプチドおよびその製造方法 |
| US7468192B2 (en) * | 2002-03-22 | 2008-12-23 | Histogenics Corporation | Method for repair of cartilage lesions |
| US7537780B2 (en) * | 2002-03-22 | 2009-05-26 | Histogenics Corporation | Method for preparing and implanting a cartilage construct to treat cartilage lesions |
| EP1364663A1 (de) * | 2002-05-21 | 2003-11-26 | Commonwealth Scientific And Industrial Research Organisation | Okulare Vorrichtungen mit funktionalisierter Oberfläche mit adhäsiven Eigenschaften |
| US7166133B2 (en) | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
| US7622562B2 (en) | 2002-06-26 | 2009-11-24 | Zimmer Orthobiologics, Inc. | Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue |
| JP5156890B2 (ja) | 2002-09-11 | 2013-03-06 | 独立行政法人物質・材料研究機構 | 高分子架橋体及びその製造方法 |
| WO2004024035A1 (en) * | 2002-09-13 | 2004-03-25 | Ocular Sciences, Inc. | Devices and methods for improving vision |
| US20060036158A1 (en) * | 2003-11-17 | 2006-02-16 | Inrad, Inc. | Self-contained, self-piercing, side-expelling marking apparatus |
| JP2004173941A (ja) * | 2002-11-27 | 2004-06-24 | Olympus Corp | カルシウム傾斜材料とその製造方法 |
| ATE457716T1 (de) | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
| FR2850282B1 (fr) * | 2003-01-27 | 2007-04-06 | Jerome Asius | Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation |
| US7877133B2 (en) | 2003-05-23 | 2011-01-25 | Senorx, Inc. | Marker or filler forming fluid |
| CA2536041A1 (en) * | 2003-11-10 | 2005-05-26 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
| US20050273002A1 (en) | 2004-06-04 | 2005-12-08 | Goosen Ryan L | Multi-mode imaging marker |
| ES2404682T3 (es) | 2003-12-11 | 2013-05-28 | Isto Technologies Inc. | Sistema de cartílago particulado |
| US7842667B2 (en) | 2003-12-22 | 2010-11-30 | Regentis Biomaterials Ltd. | Matrix composed of a naturally-occurring protein backbone cross linked by a synthetic polymer and methods of generating and using same |
| DK1722834T3 (da) | 2003-12-22 | 2012-10-22 | Regentis Biomaterials Ltd | Matrix, som omfatter naturligt forekommende tværbundet proteinskelet |
| US20050142161A1 (en) * | 2003-12-30 | 2005-06-30 | Freeman Lynetta J. | Collagen matrix for soft tissue augmentation |
| CN104174071A (zh) | 2004-04-28 | 2014-12-03 | 安希奥设备国际有限责任公司 | 用于形成交联生物材料的组合物和系统及关联的制备方法与用途 |
| CA2566961A1 (en) | 2004-05-20 | 2005-12-08 | Coopervision, Inc. | Corneal onlays and wavefront aberration correction to enhance vision |
| US9561309B2 (en) | 2004-05-27 | 2017-02-07 | Advanced Cardiovascular Systems, Inc. | Antifouling heparin coatings |
| US8512730B2 (en) | 2004-07-12 | 2013-08-20 | Isto Technologies, Inc. | Methods of tissue repair and compositions therefor |
| CA2577025C (en) * | 2004-08-13 | 2014-01-28 | Ottawa Health Research Institute | Vision enhancing ophthalmic devices and related methods and compositions |
| CA2581093C (en) | 2004-09-17 | 2014-11-18 | Angiotech Biomaterials Corporation | Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use |
| EA016776B9 (ru) | 2004-09-30 | 2012-11-30 | Ковалон Текнолоджиз Инк. | Неадгезивные эластичные желатиновые матрицы |
| US8419656B2 (en) * | 2004-11-22 | 2013-04-16 | Bard Peripheral Vascular, Inc. | Post decompression marker introducer system |
| EP1846505B1 (de) | 2005-02-09 | 2015-11-11 | Covidien LP | Synthetische dichtungsmittel |
| US10357328B2 (en) | 2005-04-20 | 2019-07-23 | Bard Peripheral Vascular, Inc. and Bard Shannon Limited | Marking device with retractable cannula |
| WO2007010623A1 (ja) | 2005-07-22 | 2007-01-25 | Phg Corporation | 新規なポリペプチド及びその製造方法 |
| AU2006282754A1 (en) | 2005-08-26 | 2007-03-01 | Zimmer, Inc. | Implants and methods for repair, replacement and treatment of joint disease |
| US8921109B2 (en) | 2005-09-19 | 2014-12-30 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
| CA2562580C (en) | 2005-10-07 | 2014-04-29 | Inrad, Inc. | Drug-eluting tissue marker |
| US7943764B2 (en) * | 2005-10-27 | 2011-05-17 | Dimitry Alekseevich Savaschuk | Method for producing sulphated glycosaminoglycans from biological tissues |
| US7883520B2 (en) | 2006-04-10 | 2011-02-08 | Forsight Labs, Llc | Corneal epithelial pocket formation systems, components and methods |
| WO2007127198A2 (en) * | 2006-04-24 | 2007-11-08 | Incept, Llc | Protein crosslinkers, crosslinking methods and applications thereof |
| WO2008051749A2 (en) * | 2006-10-23 | 2008-05-02 | C. R. Bard, Inc. | Breast marker |
| US9579077B2 (en) | 2006-12-12 | 2017-02-28 | C.R. Bard, Inc. | Multiple imaging mode tissue marker |
| US8401622B2 (en) | 2006-12-18 | 2013-03-19 | C. R. Bard, Inc. | Biopsy marker with in situ-generated imaging properties |
| US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
| US7718616B2 (en) | 2006-12-21 | 2010-05-18 | Zimmer Orthobiologics, Inc. | Bone growth particles and osteoinductive composition thereof |
| AU2008240191B2 (en) | 2007-04-12 | 2013-09-19 | Zimmer, Inc. | Compositions and methods for tissue repair |
| PL2136850T3 (pl) * | 2007-04-13 | 2012-07-31 | Kuros Biosurgery Ag | Polimeryczny uszczelniacz tkankowy |
| EP2152743A2 (de) * | 2007-05-23 | 2010-02-17 | Allergan, Inc. | Quervernetztes collagen und anwendungen davon |
| US9125807B2 (en) | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery |
| US20100184886A1 (en) * | 2007-07-12 | 2010-07-22 | Huiguang Kou | Nitrocellulose based dispersant |
| US8318695B2 (en) * | 2007-07-30 | 2012-11-27 | Allergan, Inc. | Tunably crosslinked polysaccharide compositions |
| US8067028B2 (en) | 2007-08-13 | 2011-11-29 | Confluent Surgical Inc. | Drug delivery device |
| US8311610B2 (en) | 2008-01-31 | 2012-11-13 | C. R. Bard, Inc. | Biopsy tissue marker |
| US8293813B2 (en) * | 2008-03-05 | 2012-10-23 | Biomet Manufacturing Corporation | Cohesive and compression resistant demineralized bone carrier matrix |
| US9327061B2 (en) | 2008-09-23 | 2016-05-03 | Senorx, Inc. | Porous bioabsorbable implant |
| JP5281358B2 (ja) * | 2008-10-27 | 2013-09-04 | 学校法人常翔学園 | 高分子、経上皮吸収促進剤、及び医薬用製剤 |
| WO2010053918A1 (en) | 2008-11-05 | 2010-05-14 | Hancock Jaffe Laboratories, Inc. | Composite containing collagen and elastin as a dermal expander and tissue filler |
| JP5453453B2 (ja) | 2008-12-30 | 2014-03-26 | シー・アール・バード・インコーポレーテッド | 組織マーカの配置のためのマーカ伝送装置 |
| US20100204570A1 (en) * | 2009-02-06 | 2010-08-12 | Paul Lubock | Anchor markers |
| CN102395401B (zh) | 2009-02-12 | 2015-08-19 | 因赛普特有限责任公司 | 经由水凝胶塞的药物递送 |
| WO2012068135A1 (en) | 2010-11-15 | 2012-05-24 | Zimmer Orthobiologics, Inc. | Bone void fillers |
| US8722854B2 (en) | 2010-12-23 | 2014-05-13 | Medskin Solutions Dr. Suwelack Ag | Degradation-stabilised, biocompatible collagen matrices |
| JP5840054B2 (ja) * | 2011-03-28 | 2016-01-06 | 地方独立行政法人東京都立産業技術研究センター | 複合材料、培養容器及び細胞培養器用仕切り部材 |
| ES2561094T3 (es) | 2011-07-28 | 2016-02-24 | Harbor Medtech, Inc. | Productos de tejidos reticulados humanos o animales y sus métodos de fabricación y uso |
| US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
| CN109200013A (zh) | 2011-12-05 | 2019-01-15 | 因赛普特有限责任公司 | 医用有机凝胶方法和组合物 |
| US10245306B2 (en) | 2012-11-16 | 2019-04-02 | Isto Technologies Ii, Llc | Flexible tissue matrix and methods for joint repair |
| US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
| WO2014121303A1 (en) | 2013-02-04 | 2014-08-07 | Northeastern University | Mechanochemical collagen assembly |
| EP2964184B1 (de) | 2013-03-04 | 2018-05-09 | Dermelle, Llc D/b/a Eternogen, LLC | Injizierbare in-situ polymerisierbare kollagenzusammensetzung |
| US9511119B2 (en) * | 2013-03-15 | 2016-12-06 | NuTech Spine, Inc. | Preparations containing hepatocyte growth factor and hyaluronic acid and methods of making and using same |
| EP2994484A4 (de) * | 2013-05-09 | 2016-11-16 | Agency Science Tech & Res | Modifizierte kollagenmoleküle |
| USD715942S1 (en) | 2013-09-24 | 2014-10-21 | C. R. Bard, Inc. | Tissue marker for intracorporeal site identification |
| USD715442S1 (en) | 2013-09-24 | 2014-10-14 | C. R. Bard, Inc. | Tissue marker for intracorporeal site identification |
| USD716450S1 (en) | 2013-09-24 | 2014-10-28 | C. R. Bard, Inc. | Tissue marker for intracorporeal site identification |
| USD716451S1 (en) | 2013-09-24 | 2014-10-28 | C. R. Bard, Inc. | Tissue marker for intracorporeal site identification |
| CN106714856B (zh) * | 2014-09-18 | 2020-03-03 | 尚卓耐斯特公司 | 含有糖胺聚糖和蛋白质的组合物 |
| US10179191B2 (en) | 2014-10-09 | 2019-01-15 | Isto Technologies Ii, Llc | Flexible tissue matrix and methods for joint repair |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| JP6560166B2 (ja) * | 2015-07-13 | 2019-08-14 | コスメディ製薬株式会社 | 薬物徐放性担体及びその製造方法 |
| WO2017103914A1 (en) * | 2015-12-17 | 2017-06-22 | Regentis Biomaterials Ltd. | Ready for use organic solvent free compositions comprising protein-polymer conjugates and uses thereof |
| EP4142647A1 (de) | 2020-05-01 | 2023-03-08 | Harbor Medtech, Inc. | Multidirektionale verstärkte minimal invasive kollagenvorrichtung mit portzugang zur weichgewebereparatur |
| EP4395796A4 (de) | 2021-09-01 | 2024-12-25 | Shanghai Qisheng Biological Preparation Co., Ltd. | Knorpelregeneration mit injizierbaren, in situ polymerisierbaren collagenzusammensetzungen mit chondrozyten oder stammzellen |
| WO2023125689A1 (en) | 2021-12-28 | 2023-07-06 | Shanghai Qisheng Biological Preparation Co., Ltd. | Hyaluronic acid-collagen copolymer compositions and medical applications thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US3949073A (en) * | 1974-11-18 | 1976-04-06 | The Board Of Trustees Of Leland Stanford Junior University | Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution |
| US4488911A (en) * | 1975-10-22 | 1984-12-18 | Luck Edward E | Non-antigenic collagen and articles of manufacture |
| US4164559A (en) * | 1977-09-21 | 1979-08-14 | Cornell Research Foundation, Inc. | Collagen drug delivery device |
| US4557764A (en) * | 1984-09-05 | 1985-12-10 | Collagen Corporation | Process for preparing malleable collagen and the product thereof |
| US4600533A (en) * | 1984-12-24 | 1986-07-15 | Collagen Corporation | Collagen membranes for medical use |
| US4642117A (en) * | 1985-03-22 | 1987-02-10 | Collagen Corporation | Mechanically sheared collagen implant material and method |
| JPH0679616B2 (ja) * | 1985-07-25 | 1994-10-12 | 株式会社高研 | 架橋化医用品 |
| JPS63502354A (ja) * | 1986-01-06 | 1988-09-08 | ザ ユニヴァーシティ オブ メルボルン | コラ−ゲン生産物 |
| US5162430A (en) * | 1988-11-21 | 1992-11-10 | Collagen Corporation | Collagen-polymer conjugates |
| US5475052A (en) * | 1988-11-21 | 1995-12-12 | Collagen Corporation | Collagen-synthetic polymer matrices prepared using a multiple step reaction |
| US5141747A (en) * | 1989-05-23 | 1992-08-25 | Minnesota Mining And Manufacturing Company | Denatured collagen membrane |
| JP3008034B2 (ja) * | 1990-04-23 | 2000-02-14 | 株式会社高研 | 体内注入可能な高濃度架橋化アテロコラ−ゲン移植用組成物 |
| AU677789B2 (en) * | 1992-07-02 | 1997-05-08 | Collagen Corporation | Biocompatible polymer conjugates |
| US5514379A (en) * | 1992-08-07 | 1996-05-07 | The General Hospital Corporation | Hydrogel compositions and methods of use |
-
1994
- 1994-05-02 US US08/236,769 patent/US5475052A/en not_active Expired - Lifetime
-
1995
- 1995-03-03 CA CA002143923A patent/CA2143923A1/en not_active Abandoned
- 1995-03-16 EP EP95103895A patent/EP0680990B1/de not_active Expired - Lifetime
- 1995-03-16 DE DE69519124T patent/DE69519124T2/de not_active Expired - Lifetime
- 1995-03-16 AT AT95103895T patent/ATE197058T1/de not_active IP Right Cessation
- 1995-03-24 AU AU15075/95A patent/AU698233B2/en not_active Expired
- 1995-04-27 JP JP7104476A patent/JPH0853548A/ja not_active Withdrawn
-
2005
- 2005-07-19 JP JP2005209324A patent/JP2005320552A/ja not_active Withdrawn
-
2006
- 2006-03-22 JP JP2006079819A patent/JP4213723B2/ja not_active Expired - Lifetime
-
2007
- 2007-12-27 JP JP2007338229A patent/JP2008110229A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0680990B1 (de) | 2000-10-18 |
| JP2008110229A (ja) | 2008-05-15 |
| AU698233B2 (en) | 1998-10-29 |
| EP0680990A1 (de) | 1995-11-08 |
| DE69519124T2 (de) | 2001-05-17 |
| CA2143923A1 (en) | 1995-11-03 |
| JP2006257428A (ja) | 2006-09-28 |
| JP2005320552A (ja) | 2005-11-17 |
| JP4213723B2 (ja) | 2009-01-21 |
| AU1507595A (en) | 1995-11-09 |
| US5475052A (en) | 1995-12-12 |
| JPH0853548A (ja) | 1996-02-27 |
| DE69519124D1 (de) | 2000-11-23 |
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