ATE198145T1 - Mukoadhäsive polymeren - Google Patents

Mukoadhäsive polymeren

Info

Publication number
ATE198145T1
ATE198145T1 AT93115758T AT93115758T ATE198145T1 AT E198145 T1 ATE198145 T1 AT E198145T1 AT 93115758 T AT93115758 T AT 93115758T AT 93115758 T AT93115758 T AT 93115758T AT E198145 T1 ATE198145 T1 AT E198145T1
Authority
AT
Austria
Prior art keywords
mucoadhesive polymers
anionic
delivery
substantive
found
Prior art date
Application number
AT93115758T
Other languages
English (en)
Inventor
Lawrence Nmn Marlin
Ronald Kenichi Yamamoto
Original Assignee
Union Carbide Chem Plastic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Union Carbide Chem Plastic filed Critical Union Carbide Chem Plastic
Application granted granted Critical
Publication of ATE198145T1 publication Critical patent/ATE198145T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Adhesive Tapes (AREA)
AT93115758T 1992-09-30 1993-09-29 Mukoadhäsive polymeren ATE198145T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/954,753 US5358706A (en) 1992-09-30 1992-09-30 Muco-adhesive polymers

Publications (1)

Publication Number Publication Date
ATE198145T1 true ATE198145T1 (de) 2001-01-15

Family

ID=25495879

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93115758T ATE198145T1 (de) 1992-09-30 1993-09-29 Mukoadhäsive polymeren

Country Status (6)

Country Link
US (1) US5358706A (de)
EP (1) EP0590655B1 (de)
JP (1) JP2969584B2 (de)
AT (1) ATE198145T1 (de)
CA (1) CA2107301C (de)
DE (1) DE69329767T2 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5099145A (en) * 1989-04-06 1992-03-24 Fuji Electric Co., Ltd. System disconnection detection circuit for a distributed location power source
US5827835A (en) * 1994-08-30 1998-10-27 Alcon Laboratories, Inc. Thermally-gelling emulsions
DK0725628T3 (da) * 1994-08-30 2001-12-27 Alcon Lab Inc Termisk geldannende lægemiddelindgivelsesvehikler indeholdende celluloseethere
US5788959A (en) * 1995-04-24 1998-08-04 University Of Maryland, Baltimore County Drug delivery device and method for employing the same
DE19539532C2 (de) * 1995-10-24 1999-02-25 Mann Gerhard Chem Pharm Fab Ophthalmisches Cromoglicat-Gelpräparat
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
CA2193149C (en) * 1995-12-22 2002-04-23 David H. Donabedian Cationic therapuetic agents and delivery systems
EP0888770A1 (de) * 1997-07-04 1999-01-07 Union Carbide Chemicals & Plastics Technology Corporation Arzneizubereitungen enthaltend kationische Polysaccharide und kationische Arzneimittel
US6277365B1 (en) 1997-09-18 2001-08-21 Bausch & Lomb Incorporated Ophthalmic composition including a cationic glycoside and an anionic therapeutic agent
US6919076B1 (en) 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
US6958148B1 (en) 1998-01-20 2005-10-25 Pericor Science, Inc. Linkage of agents to body tissue using microparticles and transglutaminase
US7691829B2 (en) * 1998-03-24 2010-04-06 Petito George D Composition and method for healing tissues
PT1228030E (pt) 1999-11-09 2005-08-31 Alcon Inc Derivados benzenoidicos do acido 15-hidroxieicosatetraenoico e metodos para a sua utilizacao no tratamento das perturbacoes do olho seco
CA2386632A1 (en) 1999-11-09 2001-05-17 Alcon, Inc. Omega chain modified 15-hydroxyeicosatetraenoic acid derivatives and methods of their use for the treatment of dry eye
DK1228027T3 (da) 1999-11-09 2004-07-19 Alcon Inc 3-heteroatomsubstituerede og to carbonhomologe af 15-HETE og fremgangsmåder til anvendelse
PT1228032E (pt) 1999-11-09 2004-10-29 Alcon Inc Composicoes contendo derivados do acido hidroxieicosatetraenoico e metodos de utilizacao para o tratamento de desordens do olho seco
WO2001034550A2 (en) 1999-11-09 2001-05-17 Alcon Universal Ltd. 15-hydroxyeicosatetraenoic acid analogs with enhanced metabolic stability and methods of their use in treating dry eye disorders
HK1045985B (en) 1999-11-09 2004-04-23 Alcon, Inc. 15-hydroxyeicosatetraenoic acid-related compounds and methods of use
AU1226001A (en) 1999-11-09 2001-06-06 Alcon Universal Limited Phospholipids of hydroxyeicosatetraenoic acid-like derivatives
US6803385B2 (en) 1999-11-09 2004-10-12 Alcon, Inc. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
PT1228028E (pt) 1999-11-09 2005-10-31 Alcon Inc Sais de hidroxieicosatetraeniato, composicoes e metodos para utilizacao no tratamento de perturbacoes da secura ocular
DE60019322T2 (de) 1999-11-09 2005-09-08 Alcon Inc. Heteroatomunterbrochene analoge von15-hydroxyeicosatetraensäure und verfahren zu deren verwendung
WO2001034553A2 (en) 1999-11-09 2001-05-17 Alcon Universal Ltd. 2,2-difluoro 15-hydroxyeicosatetraenoic acid analogs and methods of use
US6552084B2 (en) 1999-11-09 2003-04-22 Alcon Universal Ltd. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
US6458854B2 (en) 1999-11-09 2002-10-01 Alcon Universal Ltd. Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
US6348508B1 (en) 2000-04-04 2002-02-19 Bausch & Lomb Incorporated Method for treating dry eye
US6702983B2 (en) * 2001-05-15 2004-03-09 Bausch & Lomb Incorporated Low ionic strength method and composition for reducing bacterial attachment to biomaterials
US20050227911A1 (en) * 2001-09-28 2005-10-13 Solubest Ltd. Hydrophilic dispersions of nanoparticles of inclusion complexes of macromolecules
DE10161149B4 (de) * 2001-12-12 2007-03-08 Ursapharm Arzneimittel Gmbh & Co. Kg Verwendung von Heparin-haltigem Ophthalmikum
GB0130603D0 (en) * 2001-12-20 2002-02-06 Renaissance Healthcare Europ L Improvements in or relating to ophthalmic solutions
MXPA04008171A (es) 2002-02-22 2004-11-26 Pharmacia Corp Formulacion oftalmica con sistema de goma.
US20030203032A1 (en) * 2002-04-25 2003-10-30 Schultz Clyde L. Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease
AU2003222668A1 (en) * 2002-04-25 2003-11-10 Rapidheal, Inc. Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease
EP2298338B1 (de) * 2002-09-16 2012-08-22 Agennix Incorporated Lactoferrin-Zusammenfassungen und Verfahren zur Behandlung von Hautwunden
US20040063591A1 (en) * 2002-09-30 2004-04-01 Bausch & Lomb Incorporated Compositions with enhanced antimicrobial efficacy against acanthamoebae
TW200416046A (en) * 2002-12-23 2004-09-01 Alcon Inc Contact lens care compositions containing chitin derivatives
US20040137079A1 (en) * 2003-01-08 2004-07-15 Cook James N. Contact lens and eye drop rewetter compositions and methods
US20050074497A1 (en) * 2003-04-09 2005-04-07 Schultz Clyde L. Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases
US9216106B2 (en) 2003-04-09 2015-12-22 Directcontact Llc Device and method for the delivery of drugs for the treatment of posterior segment disease
US20050255144A1 (en) * 2003-04-09 2005-11-17 Directcontact Llc Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases
US6984628B2 (en) * 2003-07-15 2006-01-10 Allergan, Inc. Ophthalmic compositions comprising trefoil factor family peptides
JP4822092B2 (ja) * 2003-09-01 2011-11-24 大正製薬株式会社 W/o/w型複合エマルション
US20050118129A1 (en) * 2003-12-01 2005-06-02 Erning Xia Gentle and enhanced preservative systems
US8759321B2 (en) * 2007-06-13 2014-06-24 Bausch & Lomb Incorporated Ophthalmic composition with hyaluronic acid and polymeric biguanide
US8119112B2 (en) * 2008-01-31 2012-02-21 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid
US20100286010A1 (en) * 2008-09-03 2010-11-11 Erning Xia Ophthalmic Compositions with Hyaluronic Acid
US20100178317A1 (en) * 2009-01-09 2010-07-15 Burke Susan E Lens Care Solutions with Hyaluronic Acid
WO2016081193A1 (en) 2014-11-18 2016-05-26 Dow Global Technologies Llc Delivering a drug to a mucosal surface
WO2016108634A2 (ko) * 2014-12-30 2016-07-07 (주)셀트리온 표피성장인자와 리포좀의 하이브리드형 다중층 나노구조체 및 그 제조방법
EP3277728B1 (de) * 2015-04-02 2023-10-04 Nutrition & Biosciences USA 1, LLC Zusammensetzung mit kationischer hydroxyethylcellulose
CN117137866A (zh) * 2018-02-28 2023-12-01 参天制药株式会社 含有地夸磷索及阳离子性聚合物的眼科用组合物
JP6966667B2 (ja) * 2019-08-27 2021-11-17 参天製薬株式会社 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472840A (en) * 1965-09-14 1969-10-14 Union Carbide Corp Quaternary nitrogen-containing cellulose ethers
US3947573A (en) * 1969-12-01 1976-03-30 Burton, Parsons And Company, Inc. Opthalmic solution
LU65997A1 (de) * 1972-09-05 1974-03-14
US4168112A (en) * 1978-01-05 1979-09-18 Polymer Technology Corporation Contact lens with a hydrophilic, polyelectrolyte complex coating and method for forming same
US4303676A (en) * 1980-03-21 1981-12-01 Balazs Endre A Hyaluronate based compositions and cosmetic formulations containing same
US4362697A (en) * 1981-04-20 1982-12-07 Miles Laboratories, Inc. Homogeneous specific binding assay test device having copolymer enhancing substance
DE3440352A1 (de) * 1984-11-05 1986-05-07 Dr. Thilo & Co GmbH, 8029 Sauerlach Dry-eye-packung
US4617186A (en) * 1984-12-28 1986-10-14 Alcon Laboratories, Inc. Sustained release drug delivery system utilizing bioadhesive polymers
US4663159A (en) * 1985-02-01 1987-05-05 Union Carbide Corporation Hydrophobe substituted, water-soluble cationic polysaccharides
IL80298A (en) * 1986-10-14 1993-01-31 Res & Dev Co Ltd Eye drops
US4913743A (en) * 1987-04-15 1990-04-03 Biomatrix, Inc. Processes for managing keratinous material using glycosaminoglycan and cationic polymer combinations
US4767463A (en) * 1987-04-15 1988-08-30 Union Carbide Corporation Glycosaminoglycan and cationic polymer combinations
IL95393A0 (en) * 1989-08-18 1991-06-30 John Morris Co Odor-masked and stabilized compositions for treating keratinous tissue,skin conditions,and promoting wound healing
US5171526A (en) * 1990-01-05 1992-12-15 Allergan, Inc. Ophthalmic compositions and methods for preserving and using same

Also Published As

Publication number Publication date
US5358706A (en) 1994-10-25
CA2107301A1 (en) 1994-03-31
JPH06192130A (ja) 1994-07-12
DE69329767D1 (de) 2001-01-25
JP2969584B2 (ja) 1999-11-02
CA2107301C (en) 2000-01-25
DE69329767T2 (de) 2001-08-30
EP0590655A1 (de) 1994-04-06
EP0590655B1 (de) 2000-12-20

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