ATE199024T1 - Spezifisch und paarweise bindende verbindungen, mit eine kovalent, in der bindungsstelle gebunden chemischen gruppe; ihre herstellung und auswahl - Google Patents

Spezifisch und paarweise bindende verbindungen, mit eine kovalent, in der bindungsstelle gebunden chemischen gruppe; ihre herstellung und auswahl

Info

Publication number
ATE199024T1
ATE199024T1 AT94918979T AT94918979T ATE199024T1 AT E199024 T1 ATE199024 T1 AT E199024T1 AT 94918979 T AT94918979 T AT 94918979T AT 94918979 T AT94918979 T AT 94918979T AT E199024 T1 ATE199024 T1 AT E199024T1
Authority
AT
Austria
Prior art keywords
pct
pair
specific
selection
production
Prior art date
Application number
AT94918979T
Other languages
English (en)
Inventor
Laurent Stephane Anne Jespers
Gregory Paul Winter
Timothy Peter Bonnert
Thomas Martin Simon
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of ATE199024T1 publication Critical patent/ATE199024T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0002—Antibodies with enzymatic activity, e.g. abzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94918979T 1993-06-30 1994-06-30 Spezifisch und paarweise bindende verbindungen, mit eine kovalent, in der bindungsstelle gebunden chemischen gruppe; ihre herstellung und auswahl ATE199024T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939313509A GB9313509D0 (en) 1993-06-30 1993-06-30 Chemisynthetic libraries
PCT/GB1994/001422 WO1995001438A1 (en) 1993-06-30 1994-06-30 Sbp members with a chemical moiety covalently bound within the binding site; production and selection thereof

Publications (1)

Publication Number Publication Date
ATE199024T1 true ATE199024T1 (de) 2001-02-15

Family

ID=10738050

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94918979T ATE199024T1 (de) 1993-06-30 1994-06-30 Spezifisch und paarweise bindende verbindungen, mit eine kovalent, in der bindungsstelle gebunden chemischen gruppe; ihre herstellung und auswahl

Country Status (11)

Country Link
US (1) US6017732A (de)
EP (1) EP0706569B1 (de)
JP (1) JPH09500016A (de)
AT (1) ATE199024T1 (de)
AU (1) AU691817B2 (de)
CA (1) CA2163979A1 (de)
DE (1) DE69426649T2 (de)
DK (1) DK0706569T3 (de)
ES (1) ES2156154T3 (de)
GB (1) GB9313509D0 (de)
WO (1) WO1995001438A1 (de)

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CN119255825A (zh) 2022-05-24 2025-01-03 第一三共株式会社 抗-cdh6抗体-药物缀合物的剂量方案
KR20250090297A (ko) 2022-10-25 2025-06-19 다이이찌 산쿄 가부시키가이샤 억제형 kir 에 대한 아고니스트를 사용한 면역 거절의 회피 방법
KR20250138255A (ko) 2023-01-27 2025-09-19 다이이찌 산쿄 가부시키가이샤 항 lrrc15 항체
TW202444760A (zh) 2023-03-29 2024-11-16 日商第一三共股份有限公司 抗ｃｄ２５抗體及抗ｃｄ２５抗體－藥物複合體
WO2024214811A1 (ja) 2023-04-14 2024-10-17 中外製薬株式会社 タンパク質含有医薬製剤の安定化方法
EP4699622A1 (de) 2023-04-19 2026-02-25 Daiichi Sankyo Company, Limited Kombination aus einem antikörper-wirkstoff-konjugat und einem anderen medikament
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DE69426649T2 (de) 2001-06-28
DE69426649D1 (de) 2001-03-08
EP0706569A1 (de) 1996-04-17
US6017732A (en) 2000-01-25
ES2156154T3 (es) 2001-06-16
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