ATE199095T1 - Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf) - Google Patents

Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf)

Info

Publication number
ATE199095T1
ATE199095T1 AT92900987T AT92900987T ATE199095T1 AT E199095 T1 ATE199095 T1 AT E199095T1 AT 92900987 T AT92900987 T AT 92900987T AT 92900987 T AT92900987 T AT 92900987T AT E199095 T1 ATE199095 T1 AT E199095T1
Authority
AT
Austria
Prior art keywords
cells
ehm
growth factor
pct
heparin binding
Prior art date
Application number
AT92900987T
Other languages
English (en)
Inventor
Michael Klagsbrun
Judith A Abraham
Shigeki Higashiyama
Gail E Besner
Original Assignee
Childrens Medical Center
Scios Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24394159&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE199095(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Childrens Medical Center, Scios Inc filed Critical Childrens Medical Center
Application granted granted Critical
Publication of ATE199095T1 publication Critical patent/ATE199095T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT92900987T 1990-10-16 1991-10-16 Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf) ATE199095T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59808290A 1990-10-16 1990-10-16
PCT/US1991/007691 WO1992006705A1 (en) 1990-10-16 1991-10-16 Heparin binding mitogen with homology to epidermal growth factor (egf)

Publications (1)

Publication Number Publication Date
ATE199095T1 true ATE199095T1 (de) 2001-02-15

Family

ID=24394159

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92900987T ATE199095T1 (de) 1990-10-16 1991-10-16 Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf)

Country Status (8)

Country Link
US (1) US5811393A (de)
EP (1) EP0559769B1 (de)
JP (1) JPH06502538A (de)
AT (1) ATE199095T1 (de)
AU (1) AU663298B2 (de)
CA (1) CA2094045A1 (de)
DE (1) DE69132530D1 (de)
WO (1) WO1992006705A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996008293A1 (en) * 1992-12-23 1996-03-21 Patrick Edison Kane Injection molded water-soluble golf ball
WO1996008274A2 (en) * 1994-09-13 1996-03-21 Prizm Pharmaceuticals, Inc. Conjugates of heparin-binding epidermal growth factor-like growth factor with targeted agents
WO1999001738A2 (en) 1997-06-30 1999-01-14 University Of Maryland, Baltimore Heparin binding-epidermal growth factor in the diagnosis of interstitial cystitis
US5876730A (en) 1997-08-07 1999-03-02 Childrens Hospital Research Foundation Heparin-binding growth factor (HBGF) polypeptides
US6191109B1 (en) 1997-10-31 2001-02-20 Children's Hospital, Inc. Methods of treating intestinal ischemia using heparin-binding epidermal growth factor
WO1999054706A2 (en) * 1998-04-17 1999-10-28 Univ Maryland Method of treating interstitial cystitis with recombinant hb-egf
EP1100523A4 (de) * 1998-08-07 2005-02-02 Gen Hospital Corp Behandlung von einer ischämie oder verletzung des zentralen nervensystems mit epidermalem wachstumsfaktor-ähnlichen polypeptiden
WO2000077195A1 (en) * 1999-06-09 2000-12-21 Biopharm Gesellschaft Zur Biotechnologischen Entw Icklung Und Zum Vertrieb Von Pharmaka Mbh Nucleic acid encoding novel egf-like growth factors
US8980952B2 (en) * 2002-03-20 2015-03-17 University Of Maryland, Baltimore Methods for treating brain swelling with a compound that blocks a non-selective cation channel
DK2438913T3 (da) 2002-03-20 2020-06-22 Univ Maryland Ikke-selektiv kationkanal i neurale celler og forbindelser, der blokerer kanalen, til anvendelse i behandling af opsvulmning af hjernen
US7498127B2 (en) * 2002-12-20 2009-03-03 Shigeki Higashiyama Method of screening cell growth inhibitor and cell growth inhibitor
US9079936B2 (en) * 2003-07-01 2015-07-14 University Of Maryland, Baltimore Derivatives of APF and methods of use
US20050096263A1 (en) 2003-10-30 2005-05-05 Keay Susan K. Novel antiproliferative factor and methods of use
ATE486606T1 (de) * 2004-09-18 2010-11-15 Univ Maryland Therapeutische mittel zum targeting des ncca-atp- kanals und verwendungsverfahren dafür
AU2005287090A1 (en) * 2004-09-18 2006-03-30 Department Of Veterans Affairs Therapeutic agents targeting the NCca-ATP channel and methods of use thereof
US20080233053A1 (en) * 2005-02-07 2008-09-25 Pharmalight Inc. Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
WO2007058843A2 (en) * 2005-11-15 2007-05-24 Lentigen Corporation Web based vector design
WO2007091958A1 (en) * 2006-02-10 2007-08-16 Dermagen Ab Novel antimicrobial peptides and use thereof
EP2069791B1 (de) * 2006-07-27 2012-01-25 University of Maryland, Baltimore Zellulärer rezeptor für antiproliferativen faktor
WO2008089103A2 (en) 2007-01-12 2008-07-24 University Of Maryland, Baltimore Targeting ncca-atp channel for organ protection following ischemic episode
WO2008098160A1 (en) * 2007-02-09 2008-08-14 University Of Maryland, Baltimore Antagonists of a non-selective cation channel in neural cells
US8093213B2 (en) * 2007-04-30 2012-01-10 Nationwide Children's Hospital, Inc. Heparin binding epidermal growth factor (HB-EGF) for use in methods of treating and preventing intestinal injury related to hemorrhagic shock and resuscitation
CA3065983C (en) 2007-06-22 2022-07-26 The United States Of America As Represented By The Department Of Veterans Affairs Inhibitors of ncca-atp channels for therapy
CA2734325A1 (en) 2008-08-18 2010-02-25 University Of Maryland, Baltimore Derivatives of apf and methods of use
WO2014152906A2 (en) 2013-03-14 2014-09-25 Research Institute At Nationwide Children's Hospital, Inc. Tissue engineered intestine
CA2964378A1 (en) * 2014-10-21 2016-04-28 The Board Of Trustees Of The Leland Stanford Junior University Promoting epithelial regeneration post tonsillectomy using heparin binding epidermal growth factor like growth factor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI890312L (fi) * 1988-01-25 1989-07-26 Oncogen Amfiregulin: ett nytt bifunktionellt tillvaext modulerande glykoprotein.
DE8802464U1 (de) * 1988-02-25 1989-06-22 Robert Bosch Gmbh, 7000 Stuttgart Kraftstoffeinspritzventil
AU617795B2 (en) * 1988-03-17 1991-12-05 Leukotech A/S Heparin-binding proteins, dna coding for them, processes for producing them as well as therapeutic preparations containing them
US6511823B1 (en) * 1990-08-20 2003-01-28 American Cyanamid Corporation Heparin binding neurotrophic factor gene sequence

Also Published As

Publication number Publication date
CA2094045A1 (en) 1992-04-17
EP0559769B1 (de) 2001-02-07
DE69132530D1 (de) 2001-03-15
EP0559769A4 (en) 1994-06-08
WO1992006705A1 (en) 1992-04-30
EP0559769A1 (de) 1993-09-15
AU663298B2 (en) 1995-10-05
AU9086991A (en) 1992-05-20
JPH06502538A (ja) 1994-03-24
US5811393A (en) 1998-09-22

Similar Documents

Publication Publication Date Title
DE69132530D1 (de) Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf)
EP0653940A4 (de) Glialmitogene faktoren, ihre herstellung und verwendung.
DE69024291D1 (de) Rezeptoren für Tumornekrosisfaktor-alpha und -beta
NO308310B1 (no) Hovedsakelig rent KGF protein og dets anvendelse
BR8301918A (pt) Proteina,sequencia de dna,veiculo de expressao replicavel,microorganismo ou cultura celular,plasmideo,composicao,cultura de celulas,utilizacao de tal proteina,processo de expressao,processo para producao de um veiculo de expressao e processo para preparacao de uma proteina uroquinase
ES8306324A1 (es) "proceso para la produccion microbiana de interferon fibroblasto humano".
ATE128184T1 (de) Expression des rekombinanten tumor-nekrosisfaktor-bindungsproteins i (tbp-i).
DE68929402D1 (de) Verfahren zur herstellung von wasserlöslichen polypeptiden
SE8900247D0 (sv) Amphiregulin: a novel bifunctional growth modulating glycoprotein
DE69823046D1 (de) Praktische in vitro sialylierung von rekombinanten glykpproteinen
DE3786592D1 (de) Transformation von trichoderma.
ATE252113T1 (de) Verwendung von wnt polypeptiden
ES8502476A1 (es) Un procedimiento para obtener polipeptidos similares a la hormona del crecimiento de ganado bovino
ATE153858T1 (de) Ligand für das neu-gen-produkt
EP0216742A3 (de) Wachstumsfaktoren
ES533485A0 (es) Procedimiento para producir un vehiculo de expresion de adn-replicable.
ATE109829T1 (de) Interleukin-7.
DE69013811D1 (de) Verfahren zur Herstellung von antiviralem Protein unter Benützung von E.coli-Transformant, das Gen, das für dieses Protein kodiert und E.coli-Vektor benützt in diesem Verfahren.
DE69016508D1 (de) Interleukin-7-Rezeptoren.
IE930018L (en) DNA sequences, recombinant DNA molecules and processes for¹producing swine growth hormone-like polypeptides
ES2123582T3 (es) Proteina con capacidad de formacion de huesos y procedimiento para su produccion.
EP0676413A3 (de) Interferon alpha/beta bindendes Protein, seine Herstellung und Anwendung.
ES8802185A1 (es) Un metodo para preparar un anticuerpo util para la deteccion de un factor de crecimiento epidermico