ATE199095T1 - Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf) - Google Patents

Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf)

Info

Publication number
ATE199095T1
ATE199095T1 AT92900987T AT92900987T ATE199095T1 AT E199095 T1 ATE199095 T1 AT E199095T1 AT 92900987 T AT92900987 T AT 92900987T AT 92900987 T AT92900987 T AT 92900987T AT E199095 T1 ATE199095 T1 AT E199095T1
Authority
AT
Austria
Prior art keywords
cells
ehm
growth factor
pct
heparin binding
Prior art date
Application number
AT92900987T
Other languages
English (en)
Inventor
Michael Klagsbrun
Judith A Abraham
Shigeki Higashiyama
Gail E Besner
Original Assignee
Childrens Medical Center
Scios Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24394159&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE199095(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Childrens Medical Center, Scios Inc filed Critical Childrens Medical Center
Application granted granted Critical
Publication of ATE199095T1 publication Critical patent/ATE199095T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT92900987T 1990-10-16 1991-10-16 Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf) ATE199095T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59808290A 1990-10-16 1990-10-16
PCT/US1991/007691 WO1992006705A1 (en) 1990-10-16 1991-10-16 Heparin binding mitogen with homology to epidermal growth factor (egf)

Publications (1)

Publication Number Publication Date
ATE199095T1 true ATE199095T1 (de) 2001-02-15

Family

ID=24394159

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92900987T ATE199095T1 (de) 1990-10-16 1991-10-16 Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf)

Country Status (8)

Country Link
US (1) US5811393A (de)
EP (1) EP0559769B1 (de)
JP (1) JPH06502538A (de)
AT (1) ATE199095T1 (de)
AU (1) AU663298B2 (de)
CA (1) CA2094045A1 (de)
DE (1) DE69132530D1 (de)
WO (1) WO1992006705A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996008293A1 (en) * 1992-12-23 1996-03-21 Patrick Edison Kane Injection molded water-soluble golf ball
WO1996008274A2 (en) * 1994-09-13 1996-03-21 Prizm Pharmaceuticals, Inc. Conjugates of heparin-binding epidermal growth factor-like growth factor with targeted agents
AU8283898A (en) 1997-06-30 1999-01-25 University Of Maryland At Baltimore Heparin binding-epidermal growth factor in the diagnosis of interstitial cystitis
US5876730A (en) 1997-08-07 1999-03-02 Childrens Hospital Research Foundation Heparin-binding growth factor (HBGF) polypeptides
US6191109B1 (en) * 1997-10-31 2001-02-20 Children's Hospital, Inc. Methods of treating intestinal ischemia using heparin-binding epidermal growth factor
US6232289B1 (en) * 1998-04-17 2001-05-15 University Of Maryland, Baltimore Method of treating interstitial cytitis with recombinant heparin-binding epidermal growth factor-like growth factor (HB-EGF)
JP2002522394A (ja) * 1998-08-07 2002-07-23 ザ ジュネラル ホスピタル コーポレーション 中枢神経系虚血または外傷の上皮増殖因子様ポリペプチドによる治療
AU6262700A (en) * 1999-06-09 2001-01-02 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Und Zum Vertrieb Von Pharmaka Mbh Nucleic acid encoding novel egf-like growth factors
US8980952B2 (en) * 2002-03-20 2015-03-17 University Of Maryland, Baltimore Methods for treating brain swelling with a compound that blocks a non-selective cation channel
ES2807274T3 (es) 2002-03-20 2021-02-22 Univ Maryland Un canal catiónico no selectivo en células neurales y compuestos que bloquean el canal para su uso en el tratamiento de la inflamación del cerebro
WO2004057330A1 (ja) * 2002-12-20 2004-07-08 Shigeki Higashiyama 細胞増殖抑制剤のスクリーニング方法および細胞増殖抑制剤
US20050096263A1 (en) * 2003-10-30 2005-05-05 Keay Susan K. Novel antiproliferative factor and methods of use
US9079936B2 (en) * 2003-07-01 2015-07-14 University Of Maryland, Baltimore Derivatives of APF and methods of use
JP5085326B2 (ja) 2004-09-18 2012-11-28 ユニバーシティ オブ メリーランド，ボルチモア ＮＣＣａ−ＡＴＰチャネルを標的とする処置剤およびその使用方法
US10583094B2 (en) * 2004-09-18 2020-03-10 University Of Maryland Therapeutic methods that target the NCCA-ATP channel
US20080233053A1 (en) * 2005-02-07 2008-09-25 Pharmalight Inc. Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
WO2007058843A2 (en) * 2005-11-15 2007-05-24 Lentigen Corporation Web based vector design
JP2009526045A (ja) * 2006-02-10 2009-07-16 デルマゲン アクティエボラーグ 新規抗菌ペプチド及びその使用
US20100055113A1 (en) * 2006-07-27 2010-03-04 The University Of Maryland, Baltimore Cellular receptor for antiproliferative factor
WO2008089103A2 (en) 2007-01-12 2008-07-24 University Of Maryland, Baltimore Targeting ncca-atp channel for organ protection following ischemic episode
US20100092469A1 (en) * 2007-02-09 2010-04-15 Simard J Marc Antagonists of a non-selective cation channel in neural cells
US8093213B2 (en) 2007-04-30 2012-01-10 Nationwide Children's Hospital, Inc. Heparin binding epidermal growth factor (HB-EGF) for use in methods of treating and preventing intestinal injury related to hemorrhagic shock and resuscitation
CA2691199C (en) 2007-06-22 2017-09-12 Marc J. Simard Inhibitors of ncca-atp channels for therapy
CA2734325A1 (en) 2008-08-18 2010-02-25 University Of Maryland, Baltimore Derivatives of apf and methods of use
WO2014152906A2 (en) 2013-03-14 2014-09-25 Research Institute At Nationwide Children's Hospital, Inc. Tissue engineered intestine
JP2017537067A (ja) * 2014-10-21 2017-12-14 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー ヘパリン結合性上皮成長因子様成長因子を用いた、扁桃摘出後の上皮再生促進の方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI890312A7 (fi) * 1988-01-25 1989-07-26 Oncogen Amfireguliini: uusi bifunktionaalinen kasvua moduloiva glykoproteiini
DE8802464U1 (de) * 1988-02-25 1989-06-22 Robert Bosch Gmbh, 7000 Stuttgart Kraftstoffeinspritzventil
HU219883B (hu) * 1988-03-17 2001-08-28 Novo-Nordisk A/S Heparinkötő proteinek, ezeket kódoló DNS és a proteineket tartalmazó gyógyszerkészítmények, valamint eljárás ezek előállítására
US6511823B1 (en) * 1990-08-20 2003-01-28 American Cyanamid Corporation Heparin binding neurotrophic factor gene sequence

Also Published As

Publication number Publication date
DE69132530D1 (de) 2001-03-15
AU663298B2 (en) 1995-10-05
JPH06502538A (ja) 1994-03-24
EP0559769B1 (de) 2001-02-07
EP0559769A4 (en) 1994-06-08
US5811393A (en) 1998-09-22
EP0559769A1 (de) 1993-09-15
WO1992006705A1 (en) 1992-04-30
CA2094045A1 (en) 1992-04-17
AU9086991A (en) 1992-05-20

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