ATE199095T1 - Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf) - Google Patents

Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf)

Info

Publication number
ATE199095T1
ATE199095T1 AT92900987T AT92900987T ATE199095T1 AT E199095 T1 ATE199095 T1 AT E199095T1 AT 92900987 T AT92900987 T AT 92900987T AT 92900987 T AT92900987 T AT 92900987T AT E199095 T1 ATE199095 T1 AT E199095T1
Authority
AT
Austria
Prior art keywords
cells
ehm
growth factor
pct
heparin binding
Prior art date
Application number
AT92900987T
Other languages
English (en)
Inventor
Michael Klagsbrun
Judith A Abraham
Shigeki Higashiyama
Gail E Besner
Original Assignee
Childrens Medical Center
Scios Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24394159&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE199095(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Childrens Medical Center, Scios Inc filed Critical Childrens Medical Center
Application granted granted Critical
Publication of ATE199095T1 publication Critical patent/ATE199095T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT92900987T 1990-10-16 1991-10-16 Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf) ATE199095T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59808290A 1990-10-16 1990-10-16
PCT/US1991/007691 WO1992006705A1 (en) 1990-10-16 1991-10-16 Heparin binding mitogen with homology to epidermal growth factor (egf)

Publications (1)

Publication Number Publication Date
ATE199095T1 true ATE199095T1 (de) 2001-02-15

Family

ID=24394159

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92900987T ATE199095T1 (de) 1990-10-16 1991-10-16 Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf)

Country Status (8)

Country Link
US (1) US5811393A (de)
EP (1) EP0559769B1 (de)
JP (1) JPH06502538A (de)
AT (1) ATE199095T1 (de)
AU (1) AU663298B2 (de)
CA (1) CA2094045A1 (de)
DE (1) DE69132530D1 (de)
WO (1) WO1992006705A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996008293A1 (en) * 1992-12-23 1996-03-21 Patrick Edison Kane Injection molded water-soluble golf ball
WO1996008274A2 (en) * 1994-09-13 1996-03-21 Prizm Pharmaceuticals, Inc. Conjugates of heparin-binding epidermal growth factor-like growth factor with targeted agents
WO1999001738A2 (en) 1997-06-30 1999-01-14 University Of Maryland, Baltimore Heparin binding-epidermal growth factor in the diagnosis of interstitial cystitis
US5876730A (en) * 1997-08-07 1999-03-02 Childrens Hospital Research Foundation Heparin-binding growth factor (HBGF) polypeptides
US6191109B1 (en) 1997-10-31 2001-02-20 Children's Hospital, Inc. Methods of treating intestinal ischemia using heparin-binding epidermal growth factor
US6232289B1 (en) * 1998-04-17 2001-05-15 University Of Maryland, Baltimore Method of treating interstitial cytitis with recombinant heparin-binding epidermal growth factor-like growth factor (HB-EGF)
EP1100523A4 (de) * 1998-08-07 2005-02-02 Gen Hospital Corp Behandlung von einer ischämie oder verletzung des zentralen nervensystems mit epidermalem wachstumsfaktor-ähnlichen polypeptiden
WO2000077195A1 (en) * 1999-06-09 2000-12-21 Biopharm Gesellschaft Zur Biotechnologischen Entw Icklung Und Zum Vertrieb Von Pharmaka Mbh Nucleic acid encoding novel egf-like growth factors
EP2438913B1 (de) 2002-03-20 2020-05-06 University of Maryland, Baltimore Nicht-selektiver Kationenkanal in neuralen Zellen und Verfahren zur Behandlung von Hirnschwellung
US8980952B2 (en) * 2002-03-20 2015-03-17 University Of Maryland, Baltimore Methods for treating brain swelling with a compound that blocks a non-selective cation channel
AU2003292599A1 (en) * 2002-12-20 2004-07-14 Shigeki Higashiyama Method of screening cell growth inhibitor and cell growth inhibitor
US20050096263A1 (en) 2003-10-30 2005-05-05 Keay Susan K. Novel antiproliferative factor and methods of use
US9079936B2 (en) * 2003-07-01 2015-07-14 University Of Maryland, Baltimore Derivatives of APF and methods of use
CN101043891A (zh) * 2004-09-18 2007-09-26 巴尔的摩马里兰大学 靶向NCCa－ATP通道的治疗剂及其使用方法
CA2580606A1 (en) 2004-09-18 2006-03-30 University Of Maryland, Baltimore Therapeutic agents targeting the ncca-atp channel and methods of use thereof
US20080233053A1 (en) * 2005-02-07 2008-09-25 Pharmalight Inc. Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
WO2007058843A2 (en) * 2005-11-15 2007-05-24 Lentigen Corporation Web based vector design
US20090312265A1 (en) * 2006-02-10 2009-12-17 Dermagen Ab Novel antimicrobial peptides and use thereof
EP2069791B1 (de) * 2006-07-27 2012-01-25 University of Maryland, Baltimore Zellulärer rezeptor für antiproliferativen faktor
CA2674949A1 (en) 2007-01-12 2008-07-24 J. Marc Simard Targeting ncca-atp channel for organ protection following ischemic episode
WO2008098160A1 (en) * 2007-02-09 2008-08-14 University Of Maryland, Baltimore Antagonists of a non-selective cation channel in neural cells
WO2008134635A1 (en) 2007-04-30 2008-11-06 Nationwide Children's Hospital Heparin binding epidermal growth factor (hb-egf) for use in methods of treating and preventing intestinal injury related to hemorrhagic shock and resuscitation
EP2167107B1 (de) 2007-06-22 2016-12-14 University of Maryland, Baltimore Inhibitoren von ncca-atp-kanälen zur therapie
CA2734325A1 (en) 2008-08-18 2010-02-25 University Of Maryland, Baltimore Derivatives of apf and methods of use
US20160022873A1 (en) 2013-03-14 2016-01-28 Research Institute At Nationwide Children's Hospital, Inc. Tissue engineered intestine
CA2964378A1 (en) * 2014-10-21 2016-04-28 The Board Of Trustees Of The Leland Stanford Junior University Promoting epithelial regeneration post tonsillectomy using heparin binding epidermal growth factor like growth factor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI890312A7 (fi) * 1988-01-25 1989-07-26 Oncogen Amfireguliini: uusi bifunktionaalinen kasvua moduloiva glykoproteiini
DE8802464U1 (de) * 1988-02-25 1989-06-22 Robert Bosch Gmbh, 7000 Stuttgart Kraftstoffeinspritzventil
JP2846385B2 (ja) * 1988-03-17 1999-01-13 ノボ・ノルデイスク エー／エス ヘパリン結合タンパク、それらをコードするｄｎａ、それらの製造方法およびそれらを含有する治療用調製品
US6511823B1 (en) * 1990-08-20 2003-01-28 American Cyanamid Corporation Heparin binding neurotrophic factor gene sequence

Also Published As

Publication number Publication date
DE69132530D1 (de) 2001-03-15
JPH06502538A (ja) 1994-03-24
AU663298B2 (en) 1995-10-05
WO1992006705A1 (en) 1992-04-30
AU9086991A (en) 1992-05-20
CA2094045A1 (en) 1992-04-17
EP0559769A1 (de) 1993-09-15
EP0559769B1 (de) 2001-02-07
US5811393A (en) 1998-09-22
EP0559769A4 (en) 1994-06-08

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