ATE199099T1 - Verfahren und zusammensetzungen für die gen therapie zur behandlung von fehlern im lipoproteinmetalbolismus - Google Patents

Verfahren und zusammensetzungen für die gen therapie zur behandlung von fehlern im lipoproteinmetalbolismus

Info

Publication number
ATE199099T1
ATE199099T1 AT96909592T AT96909592T ATE199099T1 AT E199099 T1 ATE199099 T1 AT E199099T1 AT 96909592 T AT96909592 T AT 96909592T AT 96909592 T AT96909592 T AT 96909592T AT E199099 T1 ATE199099 T1 AT E199099T1
Authority
AT
Austria
Prior art keywords
metalbolism
lipoprotein
compositions
methods
gene therapy
Prior art date
Application number
AT96909592T
Other languages
English (en)
Inventor
James M Wilson
Karen Kozarsky
Jerome Strauss Iii
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Application granted granted Critical
Publication of ATE199099T1 publication Critical patent/ATE199099T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10344—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT96909592T 1995-02-24 1996-02-23 Verfahren und zusammensetzungen für die gen therapie zur behandlung von fehlern im lipoproteinmetalbolismus ATE199099T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/393,734 US5652224A (en) 1995-02-24 1995-02-24 Methods and compositions for gene therapy for the treatment of defects in lipoprotein metabolism
PCT/US1996/003041 WO1996026286A1 (en) 1995-02-24 1996-02-23 Methods and compositions for gene therapy for the treatment of defects in lipoprotein metabolism

Publications (1)

Publication Number Publication Date
ATE199099T1 true ATE199099T1 (de) 2001-02-15

Family

ID=23556020

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96909592T ATE199099T1 (de) 1995-02-24 1996-02-23 Verfahren und zusammensetzungen für die gen therapie zur behandlung von fehlern im lipoproteinmetalbolismus

Country Status (13)

Country Link
US (4) US5652224A (de)
EP (1) EP0811074B1 (de)
JP (1) JP3868489B2 (de)
AT (1) ATE199099T1 (de)
AU (1) AU696979B2 (de)
CA (1) CA2213254C (de)
DE (1) DE69611753T2 (de)
DK (1) DK0811074T3 (de)
ES (1) ES2155932T3 (de)
GR (1) GR3035812T3 (de)
MX (1) MX9706485A (de)
PT (1) PT811074E (de)
WO (1) WO1996026286A1 (de)

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Also Published As

Publication number Publication date
DE69611753T2 (de) 2001-08-09
AU696979B2 (en) 1998-09-24
CA2213254A1 (en) 1996-08-29
JPH11500623A (ja) 1999-01-19
EP0811074B1 (de) 2001-02-07
US6887463B2 (en) 2005-05-03
EP0811074A1 (de) 1997-12-10
ES2155932T3 (es) 2001-06-01
WO1996026286A1 (en) 1996-08-29
JP3868489B2 (ja) 2007-01-17
DE69611753D1 (de) 2001-03-15
US20050112103A1 (en) 2005-05-26
US5652224A (en) 1997-07-29
US6174527B1 (en) 2001-01-16
CA2213254C (en) 2009-05-12
US20020182182A1 (en) 2002-12-05
US7306794B2 (en) 2007-12-11
PT811074E (pt) 2001-07-31
DK0811074T3 (da) 2001-06-18
AU5303196A (en) 1996-09-11
GR3035812T3 (en) 2001-07-31
MX9706485A (es) 1997-11-29

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