ATE199247T1 - Verfahren zur herstellung von 1-aryl-1- cyanocyclobutan-derivaten - Google Patents

Verfahren zur herstellung von 1-aryl-1- cyanocyclobutan-derivaten

Info

Publication number
ATE199247T1
ATE199247T1 AT96941602T AT96941602T ATE199247T1 AT E199247 T1 ATE199247 T1 AT E199247T1 AT 96941602 T AT96941602 T AT 96941602T AT 96941602 T AT96941602 T AT 96941602T AT E199247 T1 ATE199247 T1 AT E199247T1
Authority
AT
Austria
Prior art keywords
derivatives
cyanocyclobutane
aryl
producing
dimethyl sulphoxide
Prior art date
Application number
AT96941602T
Other languages
English (en)
Inventor
Stephen John Barker
Sharon Michelle Clark
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Application granted granted Critical
Publication of ATE199247T1 publication Critical patent/ATE199247T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Catalysts (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
AT96941602T 1995-12-02 1996-11-28 Verfahren zur herstellung von 1-aryl-1- cyanocyclobutan-derivaten ATE199247T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9524681.5A GB9524681D0 (en) 1995-12-02 1995-12-02 Chemical process
PCT/EP1996/005246 WO1997020810A1 (en) 1995-12-02 1996-11-28 Process for the preparation of 1-aryl-1-cyanocyclobutane derivatives

Publications (1)

Publication Number Publication Date
ATE199247T1 true ATE199247T1 (de) 2001-03-15

Family

ID=10784817

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96941602T ATE199247T1 (de) 1995-12-02 1996-11-28 Verfahren zur herstellung von 1-aryl-1- cyanocyclobutan-derivaten

Country Status (28)

Country Link
US (1) US6545173B1 (de)
EP (1) EP0863868B1 (de)
JP (1) JP2000501402A (de)
KR (1) KR19990071838A (de)
CN (1) CN1075057C (de)
AT (1) ATE199247T1 (de)
AU (1) AU717603B2 (de)
BG (1) BG63498B1 (de)
BR (1) BR9611683A (de)
CA (1) CA2235043A1 (de)
CZ (1) CZ164798A3 (de)
DE (1) DE69611835T2 (de)
DK (1) DK0863868T3 (de)
ES (1) ES2154848T3 (de)
GB (1) GB9524681D0 (de)
GR (1) GR3035572T3 (de)
HU (1) HUP9903481A3 (de)
IL (1) IL124341A (de)
MX (1) MX9804022A (de)
NO (1) NO309265B1 (de)
NZ (1) NZ323896A (de)
PL (1) PL185047B1 (de)
PT (1) PT863868E (de)
RU (1) RU2179168C2 (de)
SI (1) SI0863868T1 (de)
SK (1) SK282470B6 (de)
TR (1) TR199800987T2 (de)
WO (1) WO1997020810A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19756091A1 (de) * 1997-12-17 1999-06-24 Hoechst Marion Roussel De Gmbh Verfahren zur Alkylierung von Alkyl- oder Benzylcyanderivaten in Gegenwart von Trialkylaminen oder -phosphinen
US6331571B1 (en) 1998-08-24 2001-12-18 Sepracor, Inc. Methods of treating and preventing attention deficit disorders
US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6974838B2 (en) 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
US6504044B2 (en) 2001-02-28 2003-01-07 Council Of Scientific And Industrial Research Process for the preparation of 1-[cyano(aryl)methyl] cyclohexanol
DE60110364T2 (de) * 2001-02-28 2006-02-16 Council Of Scientific And Industrial Research Verfahren zur Herstellung von 1-(Cyan(aryl)methyl)cyclohexanol
US6610887B2 (en) 2001-04-13 2003-08-26 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
AT503354B1 (de) * 2006-02-22 2008-07-15 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von 3,4-disubstituierten phenylessigsäuren, sowie neue zwischenverbindungen
CZ2008352A3 (cs) * 2008-06-09 2009-09-09 Lucební závody Draslovka a. s. Kolín Zpusob výroby cykloalkankarbonitrilu

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3526656A (en) 1967-05-25 1970-09-01 Parke Davis & Co (1-arylcyclobutyl)carbonyl carbamic acid derivatives
US4220591A (en) 1975-11-26 1980-09-02 Commonwealth Scientific And Industrial Research Organization Insecticidal esters
AU4244478A (en) 1977-12-19 1979-06-28 Commw Scient Ind Res Org Cyclobutane carboxylic acids and esters and insecticides
ZA821577B (en) * 1981-04-06 1983-03-30 Boots Co Plc Therapeutic agents
IE52768B1 (en) 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
GB8501192D0 (en) * 1985-01-17 1985-02-20 Boots Co Plc Therapeutic agents
SU1705280A1 (ru) * 1989-08-14 1992-01-15 Новосибирский институт органической химии СО АН СССР Способ получени пара-алкилбензонитрилов
ZA925185B (en) 1991-07-18 1993-04-29 Hoffmann La Roche Dithianes.
GB9127306D0 (en) 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents
GB9309749D0 (en) 1993-05-12 1993-06-23 Boots Co Plc Therapeutic agents
RO117377B1 (ro) 1993-06-22 2002-02-28 Boots Co Plc Derivati de tetrahidroizochinolina, procedeu de preparare, compozitie farmaceutica care ii contine si metoda de tratament

Also Published As

Publication number Publication date
DE69611835D1 (de) 2001-03-29
ES2154848T3 (es) 2001-04-16
SI0863868T1 (en) 2001-06-30
JP2000501402A (ja) 2000-02-08
BG63498B1 (bg) 2002-03-29
TR199800987T2 (xx) 1998-09-21
SK282470B6 (sk) 2002-02-05
WO1997020810A1 (en) 1997-06-12
SK62698A3 (en) 1999-02-11
BG102473A (en) 1999-05-31
NO982474D0 (no) 1998-05-29
CN1203585A (zh) 1998-12-30
CZ164798A3 (cs) 1998-09-16
NO982474L (no) 1998-05-29
KR19990071838A (ko) 1999-09-27
GB9524681D0 (en) 1996-01-31
EP0863868B1 (de) 2001-02-21
MX9804022A (es) 1998-09-30
NZ323896A (en) 2000-01-28
AU1093997A (en) 1997-06-27
CA2235043A1 (en) 1997-06-12
DE69611835T2 (de) 2001-06-07
HUP9903481A1 (hu) 2001-01-29
EP0863868A1 (de) 1998-09-16
PL185047B1 (pl) 2003-02-28
RU2179168C2 (ru) 2002-02-10
WO1997020810A8 (en) 2000-10-05
US6545173B1 (en) 2003-04-08
DK0863868T3 (da) 2001-03-19
AU717603B2 (en) 2000-03-30
PL326926A1 (en) 1998-11-09
CN1075057C (zh) 2001-11-21
IL124341A0 (en) 1998-12-06
NO309265B1 (no) 2001-01-08
BR9611683A (pt) 1999-03-02
IL124341A (en) 2001-09-13
GR3035572T3 (en) 2001-06-29
HUP9903481A3 (en) 2001-11-28
PT863868E (pt) 2001-06-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee