ATE199394T1 - Gag-env fusion-antigen aus hiv - Google Patents

Gag-env fusion-antigen aus hiv

Info

Publication number: ATE199394T1
Authority: AT; Austria
Prior art keywords: gag; env; hiv antigen; hiv; peptide
Prior art date: 1992-06-04

Application number

AT92311006T

Other languages

English (en)

Inventor

Atsushi Saito

Hideo Sinagawa

Atsuo Nakata

Original Assignee

Univ Osaka Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-06-04

Filing date

1992-12-02

Publication date

2001-03-15

1992-12-02 Application filed by Univ Osaka Res Found filed Critical Univ Osaka Res Found

2001-03-15 Application granted granted Critical

2001-03-15 Publication of ATE199394T1 publication Critical patent/ATE199394T1/de

Links

239000000427 antigen Substances 0.000 title abstract 6
102000036639 antigens Human genes 0.000 title abstract 6
108091007433 antigens Proteins 0.000 title abstract 6
230000004927 fusion Effects 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 4
125000003275 alpha amino acid group Chemical group 0.000 abstract 2
239000003153 chemical reaction reagent Substances 0.000 abstract 2
208000030507 AIDS Diseases 0.000 abstract 1
101710177291 Gag polyprotein Proteins 0.000 abstract 1
101710125418 Major capsid protein Proteins 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
108020001507 fusion proteins Proteins 0.000 abstract 1
102000037865 fusion proteins Human genes 0.000 abstract 1
108700004026 gag Genes Proteins 0.000 abstract 1
101150098622 gag gene Proteins 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
229960005486 vaccine Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/974—Aids related test

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Pharmacology & Pharmacy (AREA)
Microbiology (AREA)
Mycology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT92311006T 1992-06-04 1992-12-02 Gag-env fusion-antigen aus hiv ATE199394T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP17027092		1992-06-04

Publications (1)

Publication Number	Publication Date
ATE199394T1 true ATE199394T1 (de)	2001-03-15

Family

ID=15901829

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92311006T ATE199394T1 (de)	1992-06-04	1992-12-02	Gag-env fusion-antigen aus hiv

Country Status (8)

Country	Link
US (2)	US5576421A (de)
EP (1)	EP0572737B1 (de)
KR (1)	KR0143977B1 (de)
CN (1)	CN1079509A (de)
AT (1)	ATE199394T1 (de)
BR (1)	BR9204851A (de)
CA (1)	CA2084386C (de)
DE (1)	DE69231705T2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995016040A2 (en) *	1993-12-10	1995-06-15	The Canadian Red Cross Society	Immunofluorescence assay for the detection of antibodies using recombinant antigens in insoluble form
DE4411718A1 (de) *	1994-04-05	1995-10-12	Gsf Forschungszentrum Umwelt	RFB-Retrovirusgenom
EP0907740A1 (de) *	1997-01-02	1999-04-14	Universidade Federal De Minas Gerais	VERFAHREN ZUR EXPRESSION UND HERSTELLUNG VON REKOMBINANTEM HYBRIDPROTEIN (p24/p17) AUS DEM HUMANEN IMMUNDEFIZIENZ VIRUS (HIV-1)
US6271354B1 (en)	1997-04-03	2001-08-07	Thomas Jefferson University	Chimeric viral proteins
DE60043856D1 (de) *	1999-12-23	2010-04-01	Medical Res Council	Verbesserungen in oder in bezug auf immunantworten gegen hiv
WO2003004657A1 (en) *	2001-07-05	2003-01-16	Chiron Corporation	Polynucleotides encoding antigenic hiv type b and/or type c polypeptides, polypeptides and uses thereof
US7786288B2 (en) *	2003-10-23	2010-08-31	Karp Nelson M	Immunizing compositions encoding an epitope obtained from the HIV-1 capsid protein cyclophilin A binding site
FR2874612A1 (fr) *	2004-08-27	2006-03-03	Commissariat Energie Atomique	Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications
EP1800126B1 (de) *	2004-09-08	2014-12-17	The United States of America as represented by the Secretary of Health and Human Services, NIH	Zusammensetzungen und verfahren für den nachweis von hiv-1/hiv-2-infektionen
KR101138930B1 (ko) *	2007-02-16	2012-04-25	(주) 에빅스젠	Ｈⅰｖｎｃ 단백질을 포함하는 ａⅰｄｓ 예방 및 치료용조성물
CN101475642B (zh) *	2008-11-07	2013-06-05	深圳市菲鹏生物股份有限公司	一种艾滋病毒重组抗原及其融合蛋白
KR102079761B1 (ko) *	2018-05-14	2020-02-20	서울대학교산학협력단	pMyong2 벡터 시스템을 이용하여 HIV-1 p24를 발현하는 재조합 BCG 및 이의 HIV-1 백신으로의 이용

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE87103T1 (de) *	1985-12-17	1993-04-15	Akzo Nv	Immunochemisches reagenz.
US4925784A (en) *	1986-04-04	1990-05-15	Hoffmann-La Roche Inc.	Expression and purification of an HTLV-III gag/env gene protein
DE3877294T2 (de) *	1987-09-04	1993-05-06	Int Murex Tech Corp	Festphasenimmunoassay fuer einen antikoerper und hierbei verwendete biologische produkte.
JPH01179687A (ja) *	1987-12-30	1989-07-17	Chemo Sero Therapeut Res Inst	Ｈｉｖ融合蛋白質
IL90048A0 (en) *	1988-04-25	1989-12-15	Merck & Co Inc	Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
ES2059823T3 (es) *	1988-05-06	1994-11-16	Ferropas Ag	Metodos y sistemas para producir antigenos de hiv.
CA2003383A1 (en) *	1988-11-23	1990-05-23	Sushil G. Devare	Synthetic dna derived recombinant hiv antigens
WO1990014355A1 (en)	1989-05-17	1990-11-29	Research Corporation Technologies, Inc.	Retrovirus-mediated secretion of recombinant products
ATE183235T1 (de) *	1990-03-21	1999-08-15	Wolf Hans Joachim Prof Dr	Für abgeänderte retrovirale gag-polypeptide kodierende dna-sequenzen und diese enthaltende impfstoffe oder aggregate davon

1992
- 1992-12-02 CA CA002084386A patent/CA2084386C/en not_active Expired - Fee Related
- 1992-12-02 DE DE69231705T patent/DE69231705T2/de not_active Expired - Fee Related
- 1992-12-02 AT AT92311006T patent/ATE199394T1/de not_active IP Right Cessation
- 1992-12-02 EP EP92311006A patent/EP0572737B1/de not_active Expired - Lifetime
- 1992-12-04 CN CN92115396A patent/CN1079509A/zh active Pending
- 1992-12-04 BR BR9204851A patent/BR9204851A/pt not_active Application Discontinuation
- 1992-12-04 KR KR1019920023362A patent/KR0143977B1/ko not_active Expired - Fee Related
1995
- 1995-01-18 US US08/375,510 patent/US5576421A/en not_active Expired - Fee Related
- 1995-06-07 US US08/487,657 patent/US5834267A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US5576421A (en)	1996-11-19
EP0572737A2 (de)	1993-12-08
CA2084386C (en)	2001-02-20
DE69231705D1 (de)	2001-04-05
BR9204851A (pt)	1994-06-07
US5834267A (en)	1998-11-10
CA2084386A1 (en)	1993-12-05
KR0143977B1 (ko)	1998-07-15
EP0572737B1 (de)	2001-02-28
KR940000117A (ko)	1994-01-03
DE69231705T2 (de)	2001-10-18
EP0572737A3 (de)	1994-11-23
CN1079509A (zh)	1993-12-15

Legal Events

Date	Code	Title	Description
2001-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
AU591054B2 (en)	1989-11-30	Pre-S gene coded peptide hepatitis B immunogens, vaccines and diagnostics
PL363071A1 (pl)	2004-11-15	Sposoby i kompozycje dla zmniejszenia replikacji HIV-1
ATE199394T1 (de)	2001-03-15	Gag-env fusion-antigen aus hiv
GR3031817T3 (en)	2000-02-29	DNA sequences encoding modified retroviral gag polypeptides and vaccines containing them or aggregates thereof.
PT1417222E (pt)	2010-10-12	Polipéptidos isolados baseados no epítopo neutralizante da proteína p17 de vih, úteis como vacinas, e anticorpos antip17 neutralizantes que reconhecem especificamente o referido polipéptido neutralizante
EP0298633A2 (de)	1989-01-11	Synthetische Polypeptide
AU630861B2 (en)	1992-11-12	Recombinant hiv-2 polypeptides
RU96108781A (ru)	1999-04-20	Пептиды, создающие нейтрализующие антитела к генетически дифергентным штаммам вич-1
ES2156902T3 (es)	2001-08-01	Peptidos que inducen la produccion de anticuerpos neutralizantes contra cepas de vih-1 geneticamente divergentes.
KR920002629A (ko)	1992-02-28	B형 간염 코어 항원의 아미노산 잔기 서열
WO1997039029A3 (en)	2001-06-28	An antigenic epitope of the a determinant of hepatitis b surface antigen and uses thereof
DK0541753T3 (da)	1997-08-04	Hidtil ukendt hybrid, opløselig og ikke-spaltelig gp160-variant
AU6393990A (en)	1991-04-18	Hiv related peptides
TH13136A (th)	1993-09-10	แอนติเจนของ hiv
KR920703102A (ko)	1992-12-17	인간 면역결핍 바이러스(human immunodeficiency virus)에 대한 항체와 선택적으로 반응하는 폴리펩타이드 및 그를 함유하는 백신(vaccines)
DK362088A (da)	1988-06-30	Fusionsproteiner og fusionsproteinpartikler
CA2085084A1 (en)	1993-06-19	Synthetic peptides comprising a cyclic hiv principal neutralizing determinant and a t-cell stimulatory epitope
GR1000021B (el)	1990-01-31	Αντιπροσωπευτικο προιον ανοσιογενους ανασυνδυαζομενης ζυμης & μεθοδος καθαρισμου της.