ATE200226T1 - Zusammensetzungen die verwendbar sind zur verabreichung von therapeutisch wirksamer polynukleotiden in eine zielzelle und ihre verwendung in gentherapie - Google Patents

Zusammensetzungen die verwendbar sind zur verabreichung von therapeutisch wirksamer polynukleotiden in eine zielzelle und ihre verwendung in gentherapie

Info

Publication number
ATE200226T1
ATE200226T1 AT98112151T AT98112151T ATE200226T1 AT E200226 T1 ATE200226 T1 AT E200226T1 AT 98112151 T AT98112151 T AT 98112151T AT 98112151 T AT98112151 T AT 98112151T AT E200226 T1 ATE200226 T1 AT E200226T1
Authority
AT
Austria
Prior art keywords
therapeutically active
target cell
gene therapy
administration
active substance
Prior art date
Application number
AT98112151T
Other languages
English (en)
Inventor
Rainer Bischoff
Hanno Kolbe
Klaus Schughart
Original Assignee
Transgene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene Sa filed Critical Transgene Sa
Application granted granted Critical
Publication of ATE200226T1 publication Critical patent/ATE200226T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98112151T 1997-07-01 1998-07-01 Zusammensetzungen die verwendbar sind zur verabreichung von therapeutisch wirksamer polynukleotiden in eine zielzelle und ihre verwendung in gentherapie ATE200226T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9708267 1997-07-01
FR9712950 1997-10-16

Publications (1)

Publication Number Publication Date
ATE200226T1 true ATE200226T1 (de) 2001-04-15

Family

ID=26233650

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98112151T ATE200226T1 (de) 1997-07-01 1998-07-01 Zusammensetzungen die verwendbar sind zur verabreichung von therapeutisch wirksamer polynukleotiden in eine zielzelle und ihre verwendung in gentherapie

Country Status (12)

Country Link
US (1) US6656734B1 (de)
EP (1) EP0890362B1 (de)
JP (1) JP3499137B2 (de)
CN (1) CN1212890A (de)
AT (1) ATE200226T1 (de)
AU (1) AU707186B2 (de)
CA (1) CA2242035C (de)
DE (1) DE69800659T2 (de)
DK (1) DK0890362T3 (de)
ES (1) ES2156421T3 (de)
GR (1) GR3035797T3 (de)
PT (1) PT890362E (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1006197A1 (de) * 1998-12-04 2000-06-07 Transgene S.A. Verwendung einer Immunkomplex zur Herstellung eines therapeutischen Mittels zur Verwendung für die Transfektion von einem Polynukleotid in Makropinozyte-Zellen
EP1013772A1 (de) * 1998-12-21 2000-06-28 Transgene S.A. Verfahren zur Herstellung einer stabilen Posiplexe-Suspension
DE60023285D1 (de) * 1999-05-05 2006-03-02 Merrion Res I Ltd Gesteigerte abgabe von auf nukleinsäuren basierenden arzneimitteln
DE19933506A1 (de) * 1999-07-16 2001-01-25 Deutsches Krebsforsch Zelluläre Aufnahme von DNA
AU1013601A (en) * 1999-10-22 2001-05-08 Aventis Pasteur Limited Method of inducing and/or enhancing an immune response to tumor antigens
ATE346925T1 (de) 2000-05-10 2006-12-15 Sanofi Pasteur Ltd Durch mage minigene kodierte immunogene polypeptide und ihre verwendungen
AU2003278036B2 (en) * 2002-10-22 2009-12-10 Aventis Pasteur Limited Anti-cancer vaccines and high-dose cytokines as adjuvants
DE602004031681D1 (de) 2003-07-21 2011-04-14 Transgene Sa Multifunktionelle Cytokine
US20120269886A1 (en) 2004-12-22 2012-10-25 Nitto Denko Corporation Therapeutic agent for pulmonary fibrosis
AU2005320014B2 (en) 2004-12-22 2011-05-26 Nitto Denko Corporation Drug carrier and drug carrier kit for inhibiting fibrosis
US9572886B2 (en) 2005-12-22 2017-02-21 Nitto Denko Corporation Agent for treating myelofibrosis
TWI407971B (zh) 2007-03-30 2013-09-11 日東電工股份有限公司 Cancer cells and tumor-related fibroblasts
US8357531B2 (en) 2007-07-03 2013-01-22 Transgene S.A. Immortalized avian cell lines
KR20100065190A (ko) 2007-09-14 2010-06-15 닛토덴코 가부시키가이샤 약물 담체
EP2636757B1 (de) * 2008-05-27 2016-11-23 Dako Denmark A/S Zusammensetzungen und Verfahren zum Nachweis von chromosomalen Abweichungen mit neuen Hybridisierungspuffern
US9303287B2 (en) 2009-02-26 2016-04-05 Dako Denmark A/S Compositions and methods for RNA hybridization applications
ES2601237T3 (es) * 2009-12-02 2017-02-14 Dako Denmark A/S Composiciones y métodos para realizar hibridaciones sin desnaturalización
GB2499480A (en) 2010-03-31 2013-08-21 Stabilitech Ltd Method for preserving alum adjuvants and alum-adjuvanted vaccines
JP5960120B2 (ja) 2010-03-31 2016-08-02 スタビリテック リミテッド ウイルス粒子の安定化
JP5869553B2 (ja) 2010-03-31 2016-02-24 スタビリテック リミテッド ウイルス粒子、ポリペプチド又は生体材料を安定化させる添加剤
WO2013046033A1 (en) 2011-09-30 2013-04-04 Dako Denmark A/S Hybridization compositions and methods using formamide
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
US11118226B2 (en) 2011-10-21 2021-09-14 Agilent Technologies, Inc. Hybridization compositions and methods
EP3587455A1 (de) 2012-10-23 2020-01-01 Emory University Gm-csf- und il-4-konjugate, zusammensetzungen und zugehörige verfahren
GB201406569D0 (en) 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
US11826423B2 (en) 2016-11-16 2023-11-28 Immunomic Therapeutics, Inc. Nucleic acids for treatment of allergies
US11203629B2 (en) 2017-04-22 2021-12-21 Immunomic Therapeutics, Inc. LAMP constructs
CA3061950A1 (en) 2017-05-02 2018-11-08 Immunomic Therapeutics, Inc. Lamp (lysosomal associated membrane protein) constructs comprising cancer antigens
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions
EP3793595A1 (de) 2018-05-15 2021-03-24 Immunomic Therapeutics, Inc. Verbesserte lamp-konstrukte mit allergenen
EP3833398A4 (de) 2018-09-21 2021-12-22 University of Connecticut Zusammensetzungen und verfahren zur wiederherstellung der paternalen ube3a-genexpression bei angelman-syndrom beim menschen
JP2022551732A (ja) 2019-10-18 2022-12-13 イミュノミック セラピューティックス， インコーポレイテッド がん抗原を含む改良ｌａｍｐ構築物
CA3247515A1 (en) 2022-04-10 2023-10-19 Immunomic Therapeutics, Inc. Bicistronic lamp constructions comprising genes that enhance the immune response and methods of their use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711955A (en) 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
JPS61139387A (ja) * 1984-12-11 1986-06-26 Nakano Vinegar Co Ltd グルコノバクタ−属酢酸菌の形質転換方法
US6048729A (en) * 1987-05-01 2000-04-11 Transkaryotic Therapies, Inc. In vivo protein production and delivery system for gene therapy
DE3911765A1 (de) 1989-04-11 1990-10-18 Zinser Textilmaschinen Gmbh Vorgarnspulenwechselwagen
US5028726A (en) * 1990-02-07 1991-07-02 The University Of Vermont And State Agricultural College Platinum amine sulfoxide complexes
FR2701953B1 (fr) 1993-02-22 1995-05-24 Centre Nat Rech Scient Protéine de fusion multi-VIP et procédé de préparation de VIP recombinant.
ATE277640T1 (de) * 1994-03-07 2004-10-15 Dow Chemical Co Bioaktive und/oder gezielte dendrimere-konjugate enthaltend genetisches material
US5739118A (en) 1994-04-01 1998-04-14 Apollon, Inc. Compositions and methods for delivery of genetic material
US5525711A (en) 1994-05-18 1996-06-11 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pteridine nucleotide analogs as fluorescent DNA probes
US5650135A (en) 1994-07-01 1997-07-22 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
US6040295A (en) * 1995-01-13 2000-03-21 Genemedicine, Inc. Formulated nucleic acid compositions and methods of administering the same for gene therapy
AU723325B2 (en) 1995-06-23 2000-08-24 President And Fellows Of Harvard College Transcriptional regulation of genes encoding vascular endothelial growth factor receptors
AUPN741696A0 (en) * 1996-01-05 1996-01-25 Commonwealth Scientific And Industrial Research Organisation Delivery of nucleic acids ii

Also Published As

Publication number Publication date
CA2242035A1 (en) 1999-01-01
DE69800659D1 (de) 2001-05-10
AU7394298A (en) 1999-01-28
EP0890362A1 (de) 1999-01-13
AU707186B2 (en) 1999-07-01
DE69800659T2 (de) 2001-10-18
ES2156421T3 (es) 2001-06-16
US6656734B1 (en) 2003-12-02
CN1212890A (zh) 1999-04-07
JP3499137B2 (ja) 2004-02-23
PT890362E (pt) 2001-09-28
DK0890362T3 (da) 2001-06-11
GR3035797T3 (en) 2001-07-31
EP0890362B1 (de) 2001-04-04
CA2242035C (en) 2004-11-23
JPH11106355A (ja) 1999-04-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee