ATE200488T1 - Thiophenverbindungen, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen - Google Patents

Thiophenverbindungen, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen

Info

Publication number: ATE200488T1
Authority: AT; Austria
Prior art keywords: production; pharmaceutical compositions; compositions containing; thiophene compounds; alkyl
Prior art date: 1995-02-23

Application number

AT96400359T

Other languages

English (en)

Inventor

Michel Wierzbicki

Frederic Sauveur

Jacqueline Bonnet

Charles Tordjman

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-23

Filing date

1996-02-22

Publication date

2001-04-15

1996-02-22 Application filed by Adir filed Critical Adir

2001-04-15 Application granted granted Critical

2001-04-15 Publication of ATE200488T1 publication Critical patent/ATE200488T1/de

Links

YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical class C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title abstract 3
239000008194 pharmaceutical composition Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004429 atom Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229930192474 thiophene Natural products 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

AT96400359T 1995-02-23 1996-02-22 Thiophenverbindungen, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen ATE200488T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9502061A FR2730996B1 (fr)	1995-02-23	1995-02-23	Nouveaux composes du thiophene, leur procede de preparation et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number	Publication Date
ATE200488T1 true ATE200488T1 (de)	2001-04-15

Family

ID=9476411

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96400359T ATE200488T1 (de)	1995-02-23	1996-02-22	Thiophenverbindungen, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen

Country Status (18)

Country	Link
US (2)	US5705525A (de)
EP (1)	EP0728755B1 (de)
JP (1)	JPH08253470A (de)
CN (1)	CN1058965C (de)
AT (1)	ATE200488T1 (de)
AU (1)	AU697832B2 (de)
CA (1)	CA2170097C (de)
CY (1)	CY2262B1 (de)
DE (1)	DE69612416T2 (de)
DK (1)	DK0728755T3 (de)
ES (1)	ES2158255T3 (de)
FI (1)	FI960795A7 (de)
FR (1)	FR2730996B1 (de)
GR (1)	GR3036192T3 (de)
NO (1)	NO314997B1 (de)
NZ (1)	NZ286045A (de)
PT (1)	PT728755E (de)
ZA (1)	ZA961472B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1019399A1 (de) *	1997-10-03	2000-07-19	Merck Frosst Canada & Co.	Aryl thiophene derivate als pde iv inhibitoren
AUPR283801A0 (en) *	2001-02-01	2001-03-01	Australian National University, The	Chemical compounds and methods
FR2860792B1 (fr)	2003-10-10	2006-02-24	Sanofi Synthelabo	Derives de thiophene-2-carboxamide, leur preparation et leur application en therapeutique
WO2021083060A1 (zh) *	2019-10-28	2021-05-06	中国科学院上海药物研究所	五元杂环氧代羧酸类化合物及其医药用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0055471A1 (de) *	1980-12-29	1982-07-07	E.I. Du Pont De Nemours And Company	Gegen Entzündung wirkende 4,5-Diaryl-alpha,alpha-bis(polyhalomethyl)-2-thiophenmethanamine
GB8525716D0 (en) *	1985-10-18	1985-11-20	Roussel Lab Ltd	Chemical compounds
FR2655043B1 (fr) *	1989-11-24	1992-02-07	Adir	Nouveaux derives du thiophene, leur procede de preparation et les compositions pharmaceutiques les renfermant.
US5571810A (en) *	1990-06-11	1996-11-05	Fujisawa Pharmaceutical Co., Ltd.	Thiophene derivatives
GB9012936D0 (en) *	1990-06-11	1990-08-01	Fujisawa Pharmaceutical Co	Thiophene derivatives,processes for preparation thereof and pharmaceutical composition comprising the same

1995
- 1995-02-23 FR FR9502061A patent/FR2730996B1/fr not_active Expired - Fee Related
1996
- 1996-02-17 CN CN96106004A patent/CN1058965C/zh not_active Expired - Fee Related
- 1996-02-21 AU AU45675/96A patent/AU697832B2/en not_active Ceased
- 1996-02-21 FI FI960795A patent/FI960795A7/fi not_active IP Right Cessation
- 1996-02-22 NZ NZ286045A patent/NZ286045A/en unknown
- 1996-02-22 JP JP8035131A patent/JPH08253470A/ja active Pending
- 1996-02-22 US US08/605,537 patent/US5705525A/en not_active Ceased
- 1996-02-22 DE DE69612416T patent/DE69612416T2/de not_active Expired - Fee Related
- 1996-02-22 CA CA002170097A patent/CA2170097C/fr not_active Expired - Fee Related
- 1996-02-22 PT PT96400359T patent/PT728755E/pt unknown
- 1996-02-22 DK DK96400359T patent/DK0728755T3/da active
- 1996-02-22 ES ES96400359T patent/ES2158255T3/es not_active Expired - Lifetime
- 1996-02-22 EP EP96400359A patent/EP0728755B1/de not_active Expired - Lifetime
- 1996-02-22 NO NO19960706A patent/NO314997B1/no unknown
- 1996-02-22 AT AT96400359T patent/ATE200488T1/de not_active IP Right Cessation
- 1996-02-23 ZA ZA961472A patent/ZA961472B/xx unknown
1999
- 1999-08-03 US US09/368,343 patent/USRE37078E1/en not_active Expired - Fee Related
2001
- 2001-07-09 GR GR20010401040T patent/GR3036192T3/el not_active IP Right Cessation
2002
- 2002-03-27 CY CY0200012A patent/CY2262B1/xx unknown

Also Published As

Publication number	Publication date
GR3036192T3 (en)	2001-10-31
FI960795A7 (fi)	1996-08-24
US5705525A (en)	1998-01-06
FR2730996B1 (fr)	1997-06-20
CN1058965C (zh)	2000-11-29
EP0728755A1 (de)	1996-08-28
USRE37078E1 (en)	2001-02-27
FR2730996A1 (fr)	1996-08-30
CN1142496A (zh)	1997-02-12
EP0728755B1 (de)	2001-04-11
ES2158255T3 (es)	2001-09-01
AU697832B2 (en)	1998-10-15
AU4567596A (en)	1996-08-29
CA2170097A1 (fr)	1996-08-24
DE69612416T2 (de)	2001-11-22
JPH08253470A (ja)	1996-10-01
NO314997B1 (no)	2003-06-23
CA2170097C (fr)	2002-02-26
DK0728755T3 (da)	2001-07-30
PT728755E (pt)	2001-09-28
CY2262B1 (en)	2003-07-04
NO960706D0 (no)	1996-02-22
FI960795A0 (fi)	1996-02-21
DE69612416D1 (de)	2001-05-17
NO960706L (no)	1996-08-26
NZ286045A (en)	1996-10-28
ZA961472B (en)	1996-08-28

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Legal Events

Date	Code	Title	Description
2005-11-15	REN	Ceased due to non-payment of the annual fee