ATE201020T1 - Benzopyranderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen - Google Patents

Benzopyranderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen

Info

Publication number
ATE201020T1
ATE201020T1 AT97402821T AT97402821T ATE201020T1 AT E201020 T1 ATE201020 T1 AT E201020T1 AT 97402821 T AT97402821 T AT 97402821T AT 97402821 T AT97402821 T AT 97402821T AT E201020 T1 ATE201020 T1 AT E201020T1
Authority
AT
Austria
Prior art keywords
alkyl
optionally substituted
alkoxycarbonyl
benzopyran derivatives
production
Prior art date
Application number
AT97402821T
Other languages
English (en)
Inventor
Timothee Muller
Claudie Moulin
Muriel Duflos
Sylvie Robert-Piessard
Baut Guillaume Le
Alain Tonnerre
Daniel-Henri Caignard
Dominique Manechez
Pierre Renard
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE201020T1 publication Critical patent/ATE201020T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT97402821T 1996-11-26 1997-11-24 Benzopyranderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen ATE201020T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9614470A FR2756284B1 (fr) 1996-11-26 1996-11-26 Nouveaux derives du benzopyrane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ATE201020T1 true ATE201020T1 (de) 2001-05-15

Family

ID=9498038

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97402821T ATE201020T1 (de) 1996-11-26 1997-11-24 Benzopyranderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen

Country Status (19)

Country Link
US (1) US5889045A (de)
EP (1) EP0844245B1 (de)
JP (1) JPH10158260A (de)
CN (1) CN1183412A (de)
AT (1) ATE201020T1 (de)
AU (1) AU720479B2 (de)
BR (1) BR9705064A (de)
CA (1) CA2222467C (de)
DE (1) DE69704755T2 (de)
DK (1) DK0844245T3 (de)
ES (1) ES2157539T3 (de)
FR (1) FR2756284B1 (de)
GR (1) GR3036242T3 (de)
HU (1) HUP9702227A3 (de)
NO (1) NO975402L (de)
NZ (1) NZ329264A (de)
PL (1) PL323339A1 (de)
PT (1) PT844245E (de)
ZA (1) ZA9710649B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999000372A1 (fr) 1997-06-27 1999-01-07 Fujisawa Pharmaceutical Co., Ltd. Sulfamides et leur utilisation medicale
WO1999043315A1 (en) * 1998-02-25 1999-09-02 Shionogi & Co., Ltd. Therapeutic agent for complication of diabetes
KR100352986B1 (ko) * 2000-04-28 2002-09-18 주식회사 태평양 세라미드 유사 화합물 및 이의 제조방법, 및 이를함유하는 화장료 조성물
AU2003221281A1 (en) * 2003-02-26 2004-09-17 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences Benzopyran compounds, process for preparing the same and their use
CN103784937B (zh) * 2005-09-16 2017-04-26 科内尔研究基金会 用于减少cd36表达的方法
EP3456707B1 (de) * 2007-11-06 2020-04-15 PTC Therapeutics, Inc. 4-(p-quinonyl)-2-hydroxybutanamid-derivate zur behandlung von mitochondrialen erkrankungen
US10676452B2 (en) 2015-05-22 2020-06-09 Sulfateq B.V. Compound for the prophylaxis or treatment of organ damage
TW201831471A (zh) * 2017-02-24 2018-09-01 盧森堡商艾伯維公司 囊腫纖化症跨膜傳導調節蛋白的調節劑及其使用方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU650036B2 (en) * 1990-07-25 1994-06-09 Teijin Limited Benzopyran derivative, production thereof, and pharmaceutical composition containing the same
FR2676056B1 (fr) * 1991-05-03 1993-07-16 Adir Nouveaux derives du benzopyranne leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
KR950009863B1 (ko) * 1991-05-22 1995-08-29 재단법인한국화학연구소 벤조피란 유도체와 그의 제조방법
TW244350B (de) * 1991-12-14 1995-04-01 Hoechst Ag
ZA93436B (en) * 1992-01-24 1993-08-25 Chugai Pharmaceutical Co Ltd Benzopyran derivatives
US5236935A (en) * 1992-05-21 1993-08-17 Korea Research Institute Of Chemical Technology Benzopyran derivatives and processes for the preparation thereof
US5516917A (en) * 1994-06-08 1996-05-14 G. D. Searle & Co. Leukotriene B4 antagonists
SI0707007T1 (en) * 1994-10-14 2002-04-30 Merck Patent Gmbh (R)-(-)-2-(5-(4-fluorophenyl)-3-pyridylmethylaminomethyl)chromane as CNS active agent
FR2733685B1 (fr) * 1995-05-05 1997-05-30 Adir Utilisation des derives du benzopyrane pour l'obtention de compositions pharmaceutiques destinees au traitement des pathologies liees a l'echangeur c1-/hc03-, na+ independant
DE19546736A1 (de) * 1995-12-14 1997-06-19 Hoechst Ag Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate

Also Published As

Publication number Publication date
HU9702227D0 (en) 1998-01-28
DE69704755D1 (de) 2001-06-13
FR2756284B1 (fr) 2000-04-28
PT844245E (pt) 2001-09-28
EP0844245A1 (de) 1998-05-27
NO975402D0 (no) 1997-11-25
HUP9702227A2 (hu) 1998-12-28
CA2222467A1 (fr) 1998-05-26
US5889045A (en) 1999-03-30
ZA9710649B (en) 1998-06-12
BR9705064A (pt) 1999-07-20
DK0844245T3 (da) 2001-06-11
AU720479B2 (en) 2000-06-01
DE69704755T2 (de) 2002-02-28
EP0844245B1 (de) 2001-05-09
CA2222467C (fr) 2002-05-28
CN1183412A (zh) 1998-06-03
HUP9702227A3 (en) 1999-03-01
ES2157539T3 (es) 2001-08-16
NZ329264A (en) 1998-04-27
FR2756284A1 (fr) 1998-05-29
PL323339A1 (en) 1998-06-08
AU4538397A (en) 1998-05-28
GR3036242T3 (en) 2001-10-31
JPH10158260A (ja) 1998-06-16
NO975402L (no) 1998-05-27

Similar Documents

Publication Publication Date Title
ATE175201T1 (de) Mono-n-substituierte 1,4,7,10- tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
FR2725986B1 (fr) Nouveaux derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EA200000391A1 (ru) Производные тиенопиримидина и тиенопиридина, полезные в качестве противораковых агентов
ATE201020T1 (de) Benzopyranderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
DE69013511D1 (de) Aminosäurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ES2105549T3 (es) Nuevos derivados fenoxi-isobutiricos sustituidos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
AR005233A1 (es) Derivados de 1,2,3,4-tetrahidroquinolina, procesos para su preparacion, una composicion farmaceutica y el uso en la elaboracion de un medicamento
DE69801400D1 (de) Chromenderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
ATE202564T1 (de) Aminomethylheterozyclischederivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ATE172976T1 (de) 3-aminochroman-spiroderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
ATE160338T1 (de) Alpha aminosäurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
KR950702953A (ko) 플루오레논 유도체, 이의 제조방법, 및 변성된 중추 또는 말초신경 복구제 및 중추 또는 말초신경 보호제(Fluorenone derivatives, process for preparing the same and central or peripheral nerve degeneration repair and protective agent)
ATE213496T1 (de) Heterozyclische verbindungen, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
DE69823411D1 (de) 2-Aminoidan Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
ATE160566T1 (de) Amphotere tricyclische verbindungen als antihistaminische und antiallergische mittel
ATE215080T1 (de) 1,2-dithiolan derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
ATE170520T1 (de) Eburnan-derivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ATE195521T1 (de) Indolizinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
TNSN95099A1 (fr) Derives d'acides quinolone et naphtyridone-carboxyliques
DE69526595D1 (de) Pyridoncarbonsäurederivate substituiert von bicyclischer aminogruppe, deren ester und salze, und bicyclisches amin als zwischenprodukt davon
ATE125807T1 (de) Flavonderivate.
DE69500198D1 (de) Zns mittel, verfahren zu seiner herstellung und dieses enthaltende pharmazeutische zubereitungen
ATE134619T1 (de) Neue pyridylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
EP0802179A4 (de) Derivate substituierter amidinonaphthylester
ATE195936T1 (de) Bis-imide derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitung

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee