ATE201195T1 - Tricyclische verbindungen - Google Patents
Tricyclische verbindungenInfo
- Publication number
- ATE201195T1 ATE201195T1 AT96935342T AT96935342T ATE201195T1 AT E201195 T1 ATE201195 T1 AT E201195T1 AT 96935342 T AT96935342 T AT 96935342T AT 96935342 T AT96935342 T AT 96935342T AT E201195 T1 ATE201195 T1 AT E201195T1
- Authority
- AT
- Austria
- Prior art keywords
- tricyclic compounds
- hydrogen
- ch2o
- chem
- useful
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- C07D333/80—Seven-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/12—[b,e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Led Devices (AREA)
- Surgical Instruments (AREA)
- Eye Examination Apparatus (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26723295 | 1995-10-16 | ||
| JP32429895 | 1995-12-13 | ||
| PCT/JP1996/002997 WO1997014672A1 (en) | 1995-10-16 | 1996-10-16 | Triciclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE201195T1 true ATE201195T1 (de) | 2001-06-15 |
Family
ID=26547771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96935342T ATE201195T1 (de) | 1995-10-16 | 1996-10-16 | Tricyclische verbindungen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5726325A (de) |
| EP (1) | EP0798288B1 (de) |
| JP (1) | JP3847786B2 (de) |
| CN (1) | CN1168133A (de) |
| AT (1) | ATE201195T1 (de) |
| AU (1) | AU700386B2 (de) |
| DE (1) | DE69612835T2 (de) |
| ES (1) | ES2159047T3 (de) |
| HU (1) | HUP9801356A3 (de) |
| NO (1) | NO972726L (de) |
| NZ (1) | NZ320580A (de) |
| WO (1) | WO1997014672A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840749A (en) * | 1989-08-25 | 1998-11-24 | Hoechst Marion Roussel, Inc. | N-hydroxy-dibenz b,e!oxepinalkylamines, N-hydroxy-dibenz b,e!oxepinalkanoic acid amides and related heterocyclic analogues |
| CN1080723C (zh) * | 1995-07-24 | 2002-03-13 | 武田药品工业株式会社 | 光学活性苯并硫杂庚英盐类的生产方法 |
| BR9808552A (pt) * | 1997-04-15 | 2000-05-23 | Kyowa Hakko Kogyo Kk | Composto tricìclico ou um sal farmaceuticamente aceitável do mesmo, e, composição farmacêutica |
| EP1074539B1 (de) | 1999-08-04 | 2007-10-17 | Sumitomo Chemical Company, Limited | Verfahren zur Herstellung von optisch aktiver 3,3,3-Trifluor-2-hydroxy-2-methylpropionsäure und deren Salze |
| HUP0303610A3 (en) * | 2001-03-30 | 2005-02-28 | Kyowa Hakko Kogyo Kk | Remedies for vesical stimulation in association with prostatauxe |
| EA200301080A1 (ru) | 2001-03-30 | 2004-04-29 | Киова Хакко Когио Ко., Лтд. | Терапевтический агент для лечения гиперфункции мочевого пузыря |
| CN1498109A (zh) * | 2001-03-30 | 2004-05-19 | Э�ͷ���ҵ��ʽ���� | 膀胱感觉过敏治疗剂 |
| US20040248926A1 (en) * | 2001-11-13 | 2004-12-09 | Hayashi Ken-Ichi | Preventive or remedy for pruritus |
| TW200400816A (en) * | 2002-06-26 | 2004-01-16 | Lilly Co Eli | Tricyclic steroid hormone nuclear receptor modulators |
| WO2004087131A1 (ja) * | 2003-03-31 | 2004-10-14 | Kyowa Hakko Kogyo Co., Ltd. | 鎮咳剤 |
| TW200501938A (en) * | 2003-06-27 | 2005-01-16 | Kyowa Hakko Kogyo Kk | A medicament for therapeutic treating overactive urinary bladder accompany with cerebrovascular disorder |
| WO2005007154A1 (ja) * | 2003-07-16 | 2005-01-27 | Kyowa Hakko Kogyo Co., Ltd. | 疼痛の予防及び／または治療剤 |
| WO2005011674A1 (ja) * | 2003-08-05 | 2005-02-10 | Kyowa Hakko Kogyo Co., Ltd. | 気管支喘息の予防及び／または治療剤 |
| FR2872159B1 (fr) * | 2004-06-28 | 2007-10-05 | Merck Sante Soc Par Actions Si | Nouveaux derives acides carboxyliques phenyliques et leur utilisation dans le traitement du diabete |
| TW200606133A (en) * | 2004-06-30 | 2006-02-16 | Sankyo Co | Substituted benzene compounds |
| DE102005022020A1 (de) * | 2005-05-12 | 2006-11-23 | Merckle Gmbh | Dibenzocycloheptanverbindungen und pharmazeutische Mittel, welche diese Verbindungen enthalten |
| RU2408584C2 (ru) | 2005-06-23 | 2011-01-10 | Мерк Шарп Энд Домэ Корп. | Ингибиторы тирозинкиназы |
| AU2006306499A1 (en) * | 2005-10-21 | 2007-05-03 | Merck Sharp & Dohme Corp. | Tyrosine kinase inhibitors |
| AU2006306517A1 (en) * | 2005-10-21 | 2007-05-03 | Merck Sharp & Dohme Corp. | Tyrosine kinase inhibitors |
| AU2006306496A1 (en) * | 2005-10-21 | 2007-05-03 | Merck Sharp & Dohme Corp. | Tyrosine kinase inhibitors |
| TW200813021A (en) * | 2006-07-10 | 2008-03-16 | Merck & Co Inc | Tyrosine kinase inhibitors |
| TW200827367A (en) * | 2006-10-26 | 2008-07-01 | Kyowa Hakko Kogyo Kk | A therapeutic agent for irritable bowel syndrome |
| EP3700334B1 (de) * | 2017-10-27 | 2026-04-08 | Immunebridge Inc. | Zusammensetzungen und verfahren zur herstellung von expandierten hämatopoetischen stammzellen unter verwendung von fluorenderivaten |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3458578A (en) * | 1965-03-22 | 1969-07-29 | Sandoz Ag | Aminodibenzocycloalkenones |
| US4477465A (en) * | 1983-03-10 | 1984-10-16 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 4,10-dihydro-10-oxothieno benzoxepins |
| JPS6310784A (ja) * | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
| GB9214120D0 (en) * | 1991-07-25 | 1992-08-12 | Ici Plc | Therapeutic amides |
-
1996
- 1996-10-16 AU AU73326/96A patent/AU700386B2/en not_active Ceased
- 1996-10-16 JP JP51568797A patent/JP3847786B2/ja not_active Expired - Fee Related
- 1996-10-16 ES ES96935342T patent/ES2159047T3/es not_active Expired - Lifetime
- 1996-10-16 HU HU9801356A patent/HUP9801356A3/hu unknown
- 1996-10-16 CN CN96191517A patent/CN1168133A/zh active Pending
- 1996-10-16 DE DE69612835T patent/DE69612835T2/de not_active Expired - Fee Related
- 1996-10-16 WO PCT/JP1996/002997 patent/WO1997014672A1/ja not_active Ceased
- 1996-10-16 US US08/849,399 patent/US5726325A/en not_active Expired - Fee Related
- 1996-10-16 NZ NZ320580A patent/NZ320580A/xx unknown
- 1996-10-16 EP EP96935342A patent/EP0798288B1/de not_active Expired - Lifetime
- 1996-10-16 AT AT96935342T patent/ATE201195T1/de active
-
1997
- 1997-06-13 NO NO972726A patent/NO972726L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1168133A (zh) | 1997-12-17 |
| ES2159047T3 (es) | 2001-09-16 |
| NO972726L (no) | 1997-08-05 |
| HUP9801356A3 (en) | 2000-07-28 |
| DE69612835D1 (de) | 2001-06-21 |
| DE69612835T2 (de) | 2001-10-04 |
| EP0798288A4 (de) | 1999-06-16 |
| AU700386B2 (en) | 1999-01-07 |
| AU7332696A (en) | 1997-05-07 |
| NZ320580A (en) | 1998-12-23 |
| US5726325A (en) | 1998-03-10 |
| EP0798288A1 (de) | 1997-10-01 |
| NO972726D0 (no) | 1997-06-13 |
| JP3847786B2 (ja) | 2006-11-22 |
| EP0798288B1 (de) | 2001-05-16 |
| WO1997014672A1 (en) | 1997-04-24 |
| HUP9801356A2 (hu) | 1998-10-28 |
| MX9704411A (es) | 1998-07-31 |
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